A mouse model of accelerated liver aging caused by a defect in DNA repair

Hepatology

Volumn 55, Issue 2, 2012, Pages 609-621

  Gregg, Siobhán Q ^a,b   Gutiérrez, Verónica ^a,b   Rasile Robinson, Andria ^b,c   Woodell, Tyler ^b   Nakao, Atsunori ^d   Ross, Mark A ^a   Michalopoulos, George K ^a   Rigatti, Lora ^a   Rothermel, Carrie E ^a   Kamileri, Irene ^e,f   Garinis, George ^e,f   Beer Stolz, Donna ^a   Niedernhofer, Laura J ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e INSTITUTE OF COMPUTER SCIENCE   (Greece)

^f UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALANINE AMINOTRANSFERASE; ALBUMIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; HYDROPEROXIDE; LIPOFUSCIN;

ADULTHOOD; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEGENERATION; DNA REPAIR; ENDOTHELIUM; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; HISTOPATHOLOGY; INFLAMMATION; INHERITANCE; LIPID STORAGE; LIVER DISEASE; LIVER DYSFUNCTION; LIVER INJURY; LIVER NECROSIS; LIVER PERFUSION; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTIAL HEPATECTOMY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCANNING ELECTRON MICROSCOPY; SENESCENCE; STELLATE CELL; TRANSCRIPTION REGULATION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WILD TYPE;

AGING; ANIMALS; CELL AGING; DISEASE MODELS, ANIMAL; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; GENE EXPRESSION PROFILING; LIVER; MICE; OXIDATIVE STRESS; PROGERIA;

EID: 84856404122     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24713     Document Type: Article

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