Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells

Genome Medicine

Volumn 6, Issue 9, 2014, Pages

  Tosti, Elena ^a   Katakowski, Joseph A ^a   Schaetzlein, Sonja ^a   Kim, Hyun Soo ^a   Ryan, Colm J ^b,c,d   Shales, Michael ^b   Roguev, Assen ^b   Krogan, Nevan J ^b,c,e   Palliser, Deborah ^a   Keogh, Michael Christopher ^a   Edelmann, Winfried ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e GLADSTONE INSTITUTES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; FLUOROURACIL; MISMATCH REPAIR PROTEIN; OLAPARIB; PROTEIN MUTS; PROTEIN MUTS ALPHA; PROTEIN MUTS BETA; PROTEINASE; SMALL INTERFERING RNA; SUMO PROTEASE ULP2; SUMO PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CHROMOSOME 2; CONSERVATION GENETICS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENDOMETRIAL CANCER CELL LINE; GENE DELETION; GENE INTERACTION; GENE SILENCING; GENETIC CONSERVATION; GENETIC SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LOSS OF FUNCTION MUTATION; MISMATCH REPAIR; MOLECULAR PHYLOGENY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; SINGLE STRANDED DNA BREAK; SUMOYLATION;

EID: 84907627833     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-014-0068-4     Document Type: Article

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