Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 43, 2008, Pages 16653-16658

  Dixon, Scott J ^a,b   Fedyshyn, Yaroslav ^a   Koh, Judice L Y ^a   Prasad, T S Keshava ^c   Chahwan, Charly ^a   Chua, Gordon ^d   Toufighi, Kiana ^a   Baryshnikova, Anastasija ^a   Hayles, Jacqueline ^e   Hoe, Kwang Lae ^f   Kim, Dong Uk ^f   Park, Han Oh ^g   Myers, Chad L ^h   Pandey, Akhilesh ^c,i   Durocher, Daniel ^b   Andrewsa, Brenda J ^a   Boone, Charles ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c Institute of Bioinformatics   (India)

^d UNIVERSITY OF CALGARY   (Canada)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^f Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^g Bioneer Corporation   (South Korea)

^h University of Minnesota   (United States)

ⁱ JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Comparative genomics; Saccharomyces cerevisiae; Schizosaccharomyces pombe; Synthetic genetic array

Indexed keywords

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA REPLICATION; EUKARYOTE; GENE INTERACTION; GENETIC ANALYSIS; GENETIC CONSERVATION; INTRACELLULAR TRANSPORT; LETHAL GENE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

GENE REGULATORY NETWORKS; GENES, FUNGAL; GENES, LETHAL; PHYLOGENY; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES;

EUKARYOTA; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

EID: 55949124306     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806261105     Document Type: Article

References (34)

1. Maxwell CA, et al. (2008) Genetic interactions: The missing links for a better understanding of cancer susceptibility, progression and treatment. Mol Cancer 7:4.
2. Hartman JLt, Garvik B, Hartwell L (2001) Principles for the buffering of genetic variation. Science 291(5506):1001-1004.
3. Boone C, Bussey H, Andrews BJ (2007) Exploring genetic interactions and networks with yeast. Nat Rev Genet 8(6):437-449.
4. Hartwell LH, Szankasi P, Roberts CJ, Murray AW, Friend SH (1997) Integrating genetic approaches into the discovery of anticancer drugs. Science 278(5340):1064-1068.
5. Tong AH, et al. (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-2368.
6. Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-813.
7. Pan X, et al. (2004) A robust toolkit for functional profiling of the yeast genome. Mol Cell 16(3):487-496.
8. Byrne AB, et al. (2007) A global analysis of genetic interactions in Caenorhabditis elegans. J Biol 6(3):8.
9. Lehner B, Crombie C, Tischler J, Fortunato A, Fraser AG (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat Genet 38(8):896-903.
10. Tischler J, Lehner B, Fraser AG (2008) Evolutionary plasticity of genetic interaction networks. Nat Genet 40(4):390-391.
11. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-391.
12. Fire A, et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391(6669):806-811.
13. Simmer F, et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1(1):E12.
14. Mani R, St Onge RP, Hartman JLt, Giaever G, Roth FP (2008) Defining genetic interaction. Proc Natl Acad Sci USA 105(9):3461-3466.
15. Hedges SB (2002) The origin and evolution of model organisms. Nat Rev Genet 3(11):838-849.
16. Aravind L, Watanabe H, Lipman DJ, Koonin EV (2000) Lineage-specific loss and divergence of functionally linked genes in eukaryotes. Proc Natl Acad Sci USA 97(21):11319-11324.
17. Sunnerhagen P (2002) Prospects for functional genomics in Schizosaccharomyces pombe. Curr Genet 42(2):73- 84.
18. Clarke L (1990) Centromeres of budding and fission yeasts. Trends Genet 6(5):150-154.
19. Rustici G, et al. (2004) Periodic gene expression program of the fission yeast cell cycle. Nat Genet 36(8):809-817.
20. Matsuyama A, et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24(7):841-847.
21. Schmidt MW, Houseman A, Ivanov AR, Wolf DA (2007) Comparative proteomic and transcriptomic profiling of the fission yeast Schizosaccharomyces pombe. Mol Syst Biol 3:79.
22. Decottignies A, Sanchez-Perez I, Nurse P (2003) Schizosaccharomyces pombe essential genes: A pilot study. Genome Res 13(3):399-406.
23. Breitkreutz BJ, et al. (2008) The BioGRID Interaction Database: 2008 update. Nucleic Acids Res 36(Database issue):D637-640.
24. Roguev A, Wiren M, Weissman JS, Krogan NJ (2007) High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nat Methods 4(10):861-866.
25. Reguly T, et al. (2006) Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. J Biol 5(4):11.
26. Zolezzi F, Fuss J, Uzawa S, Linn S (2002) Characterization of a Schizosaccharomyces pombe strain deleted for a sequence homologue of the human damaged DNA binding 1 (DDB1) gene. J Biol Chem 277(43):41183-41191.
27. Sakaguchi C, Morishita T, Shinagawa H, Hishida T (2008) Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair. BMC Mol Biol 9:27.
28. Lopez-Fanarraga M, Avila J, Guasch A, Coll M, Zabala JC (2001) Review: Postchaperonin tubulin folding cofactors and their role in microtubule dynamics. J Struct Biol 135(2):219-229.
29. Boyartchuk VL, Ashby MN, Rine J (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275(5307):1796-1800.
30. Tam A, Schmidt WK, Michaelis S (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-46806.
31. Tarailo M, Tarailo S, Rose AM (2007) Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components. Genetics 177(4):2525-2530.
32. Polevoda B, Sherman F (2001) NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p. J Biol Chem 276(23):20154-20159.
33. Kaelin WG, Jr. (2005) The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 5(9):689-698.
34. Zheng L, et al. (2007) Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nat Med 13(7):812-819.