-
1
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
-
DOI 10.1016/S0140-6736(06)68770-9, PII S0140673606687709
-
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006;367:1747-1757. (Pubitemid 43767064)
-
(2006)
Lancet
, vol.367
, Issue.9524
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
2
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
-
DOI 10.1016/S0140-6736(96)07492-2
-
Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997;349:1498-1504. (Pubitemid 27216360)
-
(1997)
Lancet
, vol.349
, Issue.9064
, pp. 1498-1504
-
-
Murray, C.J.L.1
Lopez, A.D.2
-
3
-
-
0034721232
-
Chronic obstructive pulmonary disease
-
DOI 10.1056/NEJM200007273430407
-
Barnes PJ. Chronic obstructive pulmonary disease. N Engl J Med 2000;343:269-280. (Pubitemid 30490396)
-
(2000)
New England Journal of Medicine
, vol.343
, Issue.4
, pp. 269-280
-
-
Barnes, P.J.1
-
5
-
-
73149091434
-
Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease
-
Aoshiba K, Nagai A. Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6:596-601.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 596-601
-
-
Aoshiba, K.1
Nagai, A.2
-
6
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965;37:614-636.
-
(1965)
Exp Cell Res
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
7
-
-
48149109243
-
Jörres RA. Aging and induced senescence as factors in the pathogenesis of lung emphysema
-
Karrasch S, Holz O, Jörres RA. Aging and induced senescence as factors in the pathogenesis of lung emphysema. Respir Med 2008;102:1215-1230.
-
(2008)
Respir Med
, vol.102
, pp. 1215-1230
-
-
Karrasch, S.1
Holz, O.2
-
10
-
-
68249096784
-
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
-
Rodier F, Coppé JP, Patil CK, Hoeijmakers WA, Muñoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol 2009;11:973-979.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 973-979
-
-
Rodier, F.1
Coppé, J.P.2
Patil, C.K.3
Hoeijmakers, W.A.4
Muñoz, D.P.5
Raza, S.R.6
Freund, A.7
Campeau, E.8
Davalos, A.R.9
Campisi, J.10
-
11
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hay flick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961;25:585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hay Flick, L.1
Moorhead, P.S.2
-
12
-
-
0015184804
-
Principle of marginotomy in template synthesis of polynucleotides
-
in Russian
-
Olovnikov AM. Principle of marginotomy in template synthesis of polynucleotides [in Russian]. Dokl Akad Nauk SSSR 1971;201:1496-1499.
-
(1971)
Dokl Akad Nauk SSSR
, vol.201
, pp. 1496-1499
-
-
Olovnikov, A.M.1
-
13
-
-
0015515155
-
Origin of concatemeric T7 DNA
-
Watson JD. Origin of concatemeric T7 DNA. Nat New Biol 1972;239:197-201.
-
(1972)
Nat New Biol
, vol.239
, pp. 197-201
-
-
Watson, J.D.1
-
14
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990;345:458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
15
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
DOI 10.1038/nature02118
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003;426:194-198. (Pubitemid 37442589)
-
(2003)
Nature
, vol.426
, Issue.6963
, pp. 194-198
-
-
D'Adda, D.F.F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
16
-
-
69949171557
-
p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence
-
Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, Bowman ED, Mathe EA, Schetter AJ, Pine SR, et al. p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat Cell Biol 2009;11:1135-1142.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1135-1142
-
-
Fujita, K.1
Mondal, A.M.2
Horikawa, I.3
Nguyen, G.H.4
Kumamoto, K.5
Sohn, J.J.6
Bowman, E.D.7
Mathe, E.A.8
Schetter, A.J.9
Pine, S.R.10
-
17
-
-
45849099050
-
Living on a break: Cellular senescence as a DNA-damage response
-
d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer 2008;8:512 -522.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 512-522
-
-
D'Adda Di Fagagna, F.1
-
18
-
-
0034682721
-
Cellular senescence: Mitotic clock or culture shock?
-
Sherr CJ, DePinho RA. Cellular senescence: mitotic clock or culture shock? Cell 2000;102:407-410.
-
(2000)
Cell
, vol.102
, pp. 407-410
-
-
Sherr, C.J.1
DePinho, R.A.2
-
19
-
-
0029040101
-
Developmental and tissue-specific regulation of mouse telomerase and telomere length
-
Prowse KR, Greider CW. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci USA 1995;92:4818-4822.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
20
-
-
0025029030
-
Hypervariable ultra-long telomeres in mice
-
Kipling D, Cooke HJ. Hypervariable ultra-long telomeres in mice. Nature 1990;347:400-402.
-
(1990)
Nature
, vol.347
, pp. 400-402
-
-
Kipling, D.1
Cooke, H.J.2
-
21
-
-
0017405185
-
Low oxygen concentration extends the lifespan of cultured human diploid cells
-
Packer L, Fuehr K. Low oxygen concentration extends the lifespan of cultured human diploid cells. Nature 1977;267:423-425. (Pubitemid 8105518)
-
(1977)
Nature
, vol.267
, Issue.5610
, pp. 423-425
-
-
Packer, L.1
Fuehr, L.2
-
22
-
-
0029051426
-
Oxidative DNA damage and senescence of human diploid fibroblast cells
-
Chen Q, Fischer A, Reagan JD, Yan LJ, Ames BN. Oxidative DNA damage and senescence of human diploid fibroblast cells. Proc Natl Acad Sci USA 1995;92:4337-4341.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4337-4341
-
-
Chen, Q.1
Fischer, A.2
Reagan, J.D.3
Yan, L.J.4
Ames, B.N.5
-
23
-
-
0029037578
-
Relevance of oxidative stress to the limited replicative capacity of cultured human diploid cells: The limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole
-
Yuan H, Kaneko T, Matsuo M. Relevance of oxidative stress to the limited replicative capacity of cultured human diploid cells: the limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole. Mech Ageing Dev 1995;81:159-168.
-
(1995)
Mech Ageing Dev
, vol.81
, pp. 159-168
-
-
Yuan, H.1
Kaneko, T.2
Matsuo, M.3
-
24
-
-
0035114576
-
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
-
DOI 10.1101/gad.859201
-
Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 2001;15:398-403. (Pubitemid 32187001)
-
(2001)
Genes and Development
, vol.15
, Issue.4
, pp. 398-403
-
-
Ramirez, R.D.1
Morales, C.P.2
Herbert, B.-S.3
Rohde, J.M.4
Passons, C.5
Shay, J.W.6
Wright, W.E.7
-
25
-
-
0035989912
-
Molecular regulation of melanocyte senescence
-
DOI 10.1034/j.1600-0749.2002.02036.x
-
Bennett DC, Medrano EE. Molecular regulation of melanocyte senescence. Pigment Cell Res 2002;15:242-250. (Pubitemid 34829528)
-
(2002)
Pigment Cell Research
, vol.15
, Issue.4
, pp. 242-250
-
-
Bennett, D.C.1
Medrano, E.E.2
-
26
-
-
0038457477
-
Human melanocyte senescence and melanoma susceptibility genes
-
DOI 10.1038/sj.onc.1206446, Melanoma
-
Bennett DC. Human melanocyte senescence and melanoma susceptibility genes. Oncogene 2003;22:3063-3069. (Pubitemid 36713756)
-
(2003)
Oncogene
, vol.22
, Issue.20
, pp. 3063-3069
-
-
Bennett, D.C.1
-
27
-
-
0028276685
-
Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1
-
DOI 10.1016/0092-8674(94)90132-5
-
Tanaka N, Ishihara M, Kitagawa M, Harada H, Kimura T, Matsuyama T, Lamphier MS, Aizawa S, Mak TW, Taniguchi T. Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Cell 1994;77:829-839. (Pubitemid 24187681)
-
(1994)
Cell
, vol.77
, Issue.6
, pp. 829-839
-
-
Tanaka, N.1
Ishihara, M.2
Kitagawa, M.3
Harada, H.4
Kimura, T.5
Matsuyama, T.6
Lamphier, M.S.7
Aizawa, S.8
Mak, T.W.9
Taniguchi, T.10
-
28
-
-
0033635597
-
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
-
Dannenberg JH, van Rossum A, Schuijff L, te Riele H. Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev 2000;14:3051-3064.
-
(2000)
Genes Dev
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
Van Rossum, A.2
Schuijff, L.3
Te Riele, H.4
-
29
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 2000;14:3037-3050.
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
30
-
-
0035793381
-
Lack of replicative senescence in normal rodent glia
-
DOI 10.1126/science.1056782
-
Mathon NF, Malcolm DS, Harrisingh MC, Cheng L, Lloyd AC. Lack of replicative senescence in normal rodent glia. Science 2001;291:872-875. (Pubitemid 32120757)
-
(2001)
Science
, vol.291
, Issue.5505
, pp. 872-875
-
-
Mathon, N.F.1
Malcolm, D.S.2
Harrisingh, M.C.3
Cheng, L.4
Lloyd, A.C.5
-
31
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983;304:596-602. (Pubitemid 13035496)
-
(1983)
Nature
, vol.304
, Issue.5927
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
32
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
DOI 10.1016/S0092-8674(00)81902-9
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602. (Pubitemid 27152402)
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
33
-
-
0033119189
-
Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts
-
Wei S, Wei S, Sedivy JM. Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts. Cancer Res 1999;59:1539-1543. (Pubitemid 29160123)
-
(1999)
Cancer Research
, vol.59
, Issue.7
, pp. 1539-1543
-
-
Wei, S.1
Wei, W.2
Sedivy, J.M.3
-
34
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
DOI 10.1038/nature03841
-
Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005;436:660-665. (Pubitemid 41117262)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
Rudolph, C.4
Peters, A.H.F.M.5
Schlegelberger, B.6
Stein, H.7
Dorken, B.8
Jenuwein, T.9
Schmitt, C.A.10
-
35
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
DOI 10.1038/nature03918
-
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005;436:725-730. (Pubitemid 41117277)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.-K.4
Dotan, Z.A.5
Niki, M.6
Koutcher, J.A.7
Scher, H.I.8
Ludwig, T.9
Gerald, W.10
Cordon-Cardo, C.11
Pandolfi, P.P.12
-
36
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
DOI 10.1038/436642a
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguría A, Zaballos A, Flores JM, Barbacid M, et al. Tumour biology: senescence in premalignant tumours. Nature 2005;436:642. (Pubitemid 41117258)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguria, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
37
-
-
23244447037
-
E600-associated senescence-like cell cycle arrest of human naevi
-
DOI 10.1038/nature03890
-
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005;436:720-724. (Pubitemid 41117276)
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.W.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
Van Der, H.C.M.A.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
38
-
-
33745712849
-
The power and the promise of oncogene-induced senescence markers
-
Collado M, Serrano M. The power and the promise of oncogene-induced senescence markers. Nat Rev Cancer 2006;6:472-476.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 472-476
-
-
Collado, M.1
Serrano, M.2
-
39
-
-
61849107031
-
SASP reflects senescence
-
Young AR, Narita M. SASP reflects senescence. EMBO Rep 2009;10:228-230.
-
(2009)
EMBO Rep
, vol.10
, pp. 228-230
-
-
Young, A.R.1
Narita, M.2
-
40
-
-
33845292259
-
A negative feedback signaling network underlies oncogene-induced senescence
-
DOI 10.1016/j.ccr.2006.10.003, PII S1535610806002893
-
Courtois-Cox S, Genther Williams SM, Reczek EE, Johnson BW, McGillicuddy LT, Johannessen CM, Hollstein PE, MacCollin M, Cichowski K. A negative feedback signaling network underlies oncogene-induced senescence. Cancer Cell 2006;10:459-472. (Pubitemid 44872980)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 459-472
-
-
Courtois-Cox, S.1
Genther, W.S.M.2
Reczek, E.E.3
Johnson, B.W.4
McGillicuddy, L.T.5
Johannessen, C.M.6
Hollstein, P.E.7
MacCollin, M.8
Cichowski, K.9
-
41
-
-
40249100323
-
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
-
DOI 10.1038/ncb1699, PII NCB1699
-
Young AP, Schlisio S, Minamishima YA, Zhang Q, Li L, Grisanzio C, Signoretti S, Kaelin WG Jr. VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. Nat Cell Biol 2008;10:361-369. (Pubitemid 351331024)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.3
, pp. 361-369
-
-
Young, A.P.1
Schisio, S.2
Minamishima, Y.A.3
Zhang, Q.4
Li, L.5
Grisanzio, C.6
Signoretti, S.7
Kaelin Jr., W.G.8
-
42
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
DOI 10.1016/S1357-2725(02)00053-5, PII S1357272502000535
-
Krtolica A, Campisi J. Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 2002;34:1401-1414. (Pubitemid 35251811)
-
(2002)
International Journal of Biochemistry and Cell Biology
, vol.34
, Issue.11
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
43
-
-
0033539169
-
Microarray analysis of replicative senescence
-
DOI 10.1016/S0960-9822(99)80420-5
-
Shelton DN, Chang E, Whittier PS, Choi D, Funk WD. Microarray analysis of replicative senescence. Curr Biol 1999;9:939-945. (Pubitemid 29442477)
-
(1999)
Current Biology
, vol.9
, Issue.17
, pp. 939-945
-
-
Shelton, D.N.1
Chang, E.2
Whittier, P.S.3
Choi, D.4
Funk, W.D.5
-
44
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 2008;6:2853-2868.
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppé, J.P.1
Patil, C.K.2
Rodier, F.3
Sun, Y.4
Muñoz, D.P.5
Goldstein, J.6
Nelson, P.S.7
Desprez, P.Y.8
Campisi, J.9
-
45
-
-
58849154235
-
Senescence-messaging secretome: SMS-ing cellular stress
-
Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer 2009;9:81-94.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 81-94
-
-
Kuilman, T.1
Peeper, D.S.2
-
46
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
DOI 10.1038/nrm2233, PII NRM2233
-
Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007;8:729-740. (Pubitemid 47312822)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
D'Adda, D.F.F.2
-
47
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol 2011;192:547-556.
-
(2011)
J Cell Biol
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
48
-
-
0036906303
-
Checkpoint signalling: Focusing on 53BP1
-
DOI 10.1038/ncb1202-e277
-
Abraham RT. Checkpoint signalling: focusing on 53BP1. Nat Cell Biol 2002;4:E277-E279. (Pubitemid 35469413)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.12
-
-
Abraham, R.T.1
-
49
-
-
77949881221
-
The senescence-associated secretory phenotype: The dark side of tumor suppression
-
Coppé JP, Desprez PY, Krtolica A, Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 2010;5:99-118.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 99-118
-
-
Coppé, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
50
-
-
7044231343
-
INK4a-RB pathway: Molecular link between cellular senescence and tumor suppression
-
DOI 10.2152/jmi.51.146
-
Ohtani N, Yamakoshi K, Takahashi A, Hara E. The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression. J Med Invest 2004;51:146-153. (Pubitemid 39610908)
-
(2004)
Journal of Medical Investigation
, vol.51
, Issue.3-4
, pp. 146-153
-
-
Ohtani, N.1
Yamakoshi, K.2
Takahashi, A.3
Hara, E.4
-
51
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
DOI 10.1016/j.cell.2005.02.003
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005;120:513-522. (Pubitemid 40269765)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 513-522
-
-
Campisi, J.1
-
52
-
-
72949096792
-
Senescence in tumours: Evidence from mice and humans
-
Collado M, Serrano M. Senescence in tumours: evidence from mice and humans. Nat Rev Cancer 2010;10:51-57.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 51-57
-
-
Collado, M.1
Serrano, M.2
-
53
-
-
79551683487
-
Cellular senescence: Putting the paradoxes in perspective
-
Campisi J. Cellular senescence: putting the paradoxes in perspective. Curr Opin Genet Dev 2011;21:107-112.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 107-112
-
-
Campisi, J.1
-
54
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky V, Yon M, Dickins RA, Hearn S, Simon J, Miething C, Yee H, Zender L, Lowe SW. Senescence of activated stellate cells limits liver fibrosis. Cell 2008;134:657-667.
-
(2008)
Cell
, vol.134
, pp. 657-667
-
-
Krizhanovsky, V.1
Yon, M.2
Dickins, R.A.3
Hearn, S.4
Simon, J.5
Miething, C.6
Yee, H.7
Zender, L.8
Lowe, S.W.9
-
55
-
-
77954243065
-
The matricellular protein CCN1 induces fibroblast senescence and restricts fi brosis in cutaneous wound healing
-
Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fi brosis in cutaneous wound healing. Nat Cell Biol 2010;12:676-685.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 676-685
-
-
Jun, J.I.1
Lau, L.F.2
-
57
-
-
80054715764
-
Telomere length is a determinant of emphysema susceptibility
-
Alder JK, Guo NN, Kembou F, Parry EM, Anderson CJ, Gorgy AI, Walsh MF, Sussan T, Biswal S, Mitzner W, et al. Telomere length is a determinant of emphysema susceptibility. Am J Respir Crit Care Med 2011;184:904-912.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 904-912
-
-
Alder, J.K.1
Guo, N.N.2
Kembou, F.3
Parry, E.M.4
Anderson, C.J.5
Gorgy, A.I.6
Walsh, M.F.7
Sussan, T.8
Biswal, S.9
Mitzner, W.10
-
58
-
-
33645781050
-
Lung fibroblasts from patients with emphysema show markers of senescence in vitro
-
Müller KC, Welker L, Paasch K, Feindt B, Erpenbeck VJ, Hohlfeld JM, Krug N, Nakashima M, Branscheid D, Magnussen H, et al . Lung fibroblasts from patients with emphysema show markers of senescence in vitro. Respir Res 2006;7:32.
-
(2006)
Respir Res
, vol.7
, pp. 32
-
-
Müller, K.C.1
Welker, L.2
Paasch, K.3
Feindt, B.4
Erpenbeck, V.J.5
Hohlfeld, J.M.6
Krug, N.7
Nakashima, M.8
Branscheid, D.9
Magnussen, H.10
-
59
-
-
2542609402
-
Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture
-
DOI 10.1183/09031936.04.00143703
-
Holz O, Zuhlke I, Jaksztat E, Muller KC, Welker L, Nakashima M, Diemel KD, Branscheid D, Magnussen H, Jorres RA. Lung fibroblasts from patients with emphysema show a reduced proliferation rate in culture. Eur Respir J 2004;24:575-579. (Pubitemid 39406130)
-
(2004)
European Respiratory Journal
, vol.24
, Issue.4
, pp. 575-579
-
-
Holz, O.1
Zuhlke, I.2
Jaksztat, E.3
Muller, K.C.4
Welker, L.5
Nakashima, M.6
Diemel, K.D.7
Branscheid, D.8
Magnussen, H.9
Jorres, R.A.10
-
60
-
-
34548277025
-
From COPD to chronic systemic inflammatory syndrome?
-
DOI 10.1016/S0140-6736(07)61383-X, PII S014067360761383X
-
Fabbri LM, Rabe KF. From COPD to chronic systemic inflammatory syndrome? Lancet 2007;370:797-799. (Pubitemid 47320803)
-
(2007)
Lancet
, vol.370
, Issue.9589
, pp. 797-799
-
-
Fabbri, L.M.1
Rabe, K.F.2
-
61
-
-
35148893108
-
Systemic effects of chronic obstructive pulmonary disease: What we know and what we don 't know (but should)
-
Agustí A. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don 't know (but should). Proc Am Thorac Soc 2007;4:522-525.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 522-525
-
-
Agustí, A.1
-
62
-
-
0033035039
-
Physiological changes in respiratory function associated with ageing
-
DOI 10.1034/j.1399-3003.1999.13a36.x
-
Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J 1999;13:197-205. (Pubitemid 29079244)
-
(1999)
European Respiratory Journal
, vol.13
, Issue.1
, pp. 197-205
-
-
Janssens, J.P.1
Pache, J.C.2
Nicod, L.P.3
-
63
-
-
0017402583
-
The natural history of chronic airflow obstruction
-
Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977;1:1645-1648. (Pubitemid 8124466)
-
(1977)
British Medical Journal
, vol.1
, Issue.6077
, pp. 1645-1648
-
-
Fletcher, C.1
Peto, R.2
-
64
-
-
0026577683
-
The senile lung: Comparison with normal and emphysematous lungs. 2. Functional aspects
-
Verbeken EK, Cauberghs M, Mertens I, Clement J, Lauweryns JM, Van de Woestijne KP. The senile lung: comparison with normal and emphysematous lungs. 2. Functional aspects. Chest 1992;101:800-809.
-
(1992)
Chest
, vol.101
, pp. 800-809
-
-
Verbeken, E.K.1
Cauberghs, M.2
Mertens, I.3
Clement, J.4
Lauweryns, J.M.5
Van De Woestijne, K.P.6
-
65
-
-
33846332748
-
Aging, the aging lung, and senile emphysema are different
-
author reply 198
-
Teramoto S, Ishii M. Aging, the aging lung, and senile emphysema are different. Am J Respir Crit Care 2007;175:197-198; author reply 198.
-
(2007)
Am J Respir Crit Care
, vol.175
, pp. 197-198
-
-
Teramoto, S.1
Ishii, M.2
-
66
-
-
0034763419
-
Smoking effect on skin wrinkling in the aged population
-
DOI 10.1046/j.1365-4362.2001.01238.x
-
Aizen E, Gilhar A. Smoking effect on skin wrinkling in the aged population. Int J Dermatol 2001;40:431-433. (Pubitemid 32982293)
-
(2001)
International Journal of Dermatology
, vol.40
, Issue.7
, pp. 431-433
-
-
Aizen, E.1
Gilhar, A.2
-
67
-
-
33745866599
-
Smoking related COPD and facial wrinkling: Is there a common susceptibility?
-
DOI 10.1136/thx.2005.053827
-
Patel BD, Loo WJ, Tasker AD, Screaton NJ, Burrows NP, Silverman EK, Lomas DA. Smoking related COPD and facial wrinkling: is there a common susceptibility? Thorax 2006;61:568-571. (Pubitemid 44035135)
-
(2006)
Thorax
, vol.61
, Issue.7
, pp. 568-571
-
-
Patel, B.D.1
Loo, W.J.2
Tasker, A.D.3
Screaton, N.J.4
Burrows, N.P.5
Silverman, E.K.6
Lomas, D.A.7
-
68
-
-
33845517056
-
Effect of smoking on skin elastic fibres: Morphometric and immunohistochemical analysis
-
DOI 10.1111/j.1365-2133.2006.07575.x
-
Just M, Ribera M, Monsó E, Lorenzo JC, Ferrándiz C. Effect of smoking on skin elastic fi bres: morphometric and immunohistochemical analysis. Br J Dermatol 2007;156:85-91. (Pubitemid 44924150)
-
(2007)
British Journal of Dermatology
, vol.156
, Issue.1
, pp. 85-91
-
-
Just, M.1
Ribera, M.2
Monso, E.3
Lorenzo, J.C.4
Ferrandiz, C.5
-
71
-
-
0029824431
-
Antioxidants in human health and disease
-
Halliwell B. Antioxidants in human health and disease. Annu Rev Nutr 1996;16:33-50. (Pubitemid 26286845)
-
(1996)
Annual Review of Nutrition
, vol.16
, pp. 33-50
-
-
Halliwell, B.1
-
72
-
-
22544463681
-
The role of oxidative stress in the pathogenesis of COPD: Implications for therapy
-
DOI 10.2165/00151829-200504030-00003
-
Rahman I. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treat Respir Med 2005;4:175-200. (Pubitemid 41018366)
-
(2005)
Treatments in Respiratory Medicine
, vol.4
, Issue.3
, pp. 175-200
-
-
Rahman, I.1
-
74
-
-
84882925367
-
Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
-
Chilosi M, Carloni A, Rossi A, Poletti V. Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema. Transl Res 2013;162:156-173.
-
(2013)
Transl Res
, vol.162
, pp. 156-173
-
-
Chilosi, M.1
Carloni, A.2
Rossi, A.3
Poletti, V.4
-
75
-
-
24344493434
-
Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease
-
Gessner C, Scheibe R, Wötzel M, Hammerschmidt S, Kuhn H, Engelmann L, Hoheisel G, Gillissen A, Sack U, Wirtz H. Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. Respir Med 2005;99:1229-1240.
-
(2005)
Respir Med
, vol.99
, pp. 1229-1240
-
-
Gessner, C.1
Scheibe, R.2
Wötzel, M.3
Hammerschmidt, S.4
Kuhn, H.5
Engelmann, L.6
Hoheisel, G.7
Gillissen, A.8
Sack, U.9
Wirtz, H.10
-
76
-
-
4344677172
-
Characterization of mainstream cigarette smoke-induced biomarker responses in ICR and C57BI/6 mice
-
DOI 10.1080/08958370490476604
-
Obot C, Lee K, Fuciarelli A, Renne R, McKinney W. Characterization of mainstream cigarette smoke-induced biomarker responses in ICR and C57Bl/6 mice. Inhal Toxicol 2004;16:701-719. (Pubitemid 39121800)
-
(2004)
Inhalation Toxicology
, vol.16
, Issue.10
, pp. 701-719
-
-
Obot, C.J.1
Lee, K.M.2
Fuciarelli, A.F.3
Renne, R.A.4
McKinney, W.J.5
-
77
-
-
0034025481
-
Monocyte chemoattractant protein 1, interleukin 8, and chronic airways inflammation in COPD
-
DOI 10.1002/(SICI)1096-9896(200004)190:5<619::AID
-
de Boer WI, Sont JK, van Schadewijk A, Stolk J, van Krieken JH, Hiemstra PS. Monocyte chemoattractant protein 1, interleukin 8, and chronic airways in fl ammation in COPD. J Pathol 2000;190:619-626. (Pubitemid 30164493)
-
(2000)
Journal of Pathology
, vol.190
, Issue.5
, pp. 619-626
-
-
De Boer, W.I.1
Sont, J.K.2
Van Schadewijk, A.3
Stolk, J.4
Van Han, K.J.5
Hiemstra, P.S.6
-
78
-
-
0036311347
-
Increased levels of the chemokines GROalpha and MCP-1 in sputum samples from patients with COPD
-
DOI 10.1136/thorax.57.7.590
-
Traves SL, Culpitt SV, Russell RE, Barnes PJ, Donnelly LE. Increased levels of the chemokines GROalpha and MCP-1 in sputum samples from patients with COPD. Thorax 2002;57:590-595. (Pubitemid 34761760)
-
(2002)
Thorax
, vol.57
, Issue.7
, pp. 590-595
-
-
Traves, S.L.1
Culpitt, S.V.2
Russell, R.E.K.3
Barnes, P.J.4
Donnelly, L.E.5
-
79
-
-
83455260199
-
Airway angiogenesis in stable and exacerbated chronic obstructive pulmonary disease
-
Kristan SS, Marc MM, Kern I, Flezar M, Suskovic S, Kosnik M, Korosec P. Airway angiogenesis in stable and exacerbated chronic obstructive pulmonary disease. Scand J Immunol 2012;75:109-114.
-
(2012)
Scand J Immunol
, vol.75
, pp. 109-114
-
-
Kristan, S.S.1
Marc, M.M.2
Kern, I.3
Flezar, M.4
Suskovic, S.5
Kosnik, M.6
Korosec, P.7
-
80
-
-
31544462308
-
Expression of epidermal growth factors and their receptors in the bronchial epithelium off subjects with chronic obstructive pulmonary disease
-
DOI 10.1309/W1AX-KGT7-UA37-X257
-
de Boer WI, Hau CM, van Schadewijk A, Stolk J, van Krieken JH, Hiemstra PS. Expression of epidermal growth factors and their receptors in the bronchial epithelium of subjects with chronic obstructive pulmonary disease. Am J Clin Pathol 2006;125:184-192. (Pubitemid 43167158)
-
(2006)
American Journal of Clinical Pathology
, vol.125
, Issue.2
, pp. 184-192
-
-
De Boer, W.I.1
Hau, C.M.2
Van Schadewijk, A.3
Stolk, J.4
Van Krieken, J.H.J.M.5
Hiemstra, P.S.6
-
81
-
-
0030595971
-
Characterization of IGFBP-3, PAI-1 and SPARC mRNA expression in senescent fibroblasts
-
DOI 10.1016/S0047-6374(96)01814-3, PII S0047637496018143
-
Wang S, Moerman EJ, Jones RA, Thweatt R, Goldstein S. Characterization of IGFBP-3, PAI-1 and SPARC mRNA expression in senescent fibroblasts. Mech Ageing Dev 1996;92:121-132. (Pubitemid 27129284)
-
(1996)
Mechanisms of Ageing and Development
, vol.92
, Issue.2-3
, pp. 121-132
-
-
Wang, S.1
Moerman, E.J.2
Jones, R.A.3
Thweatt, R.4
Goldstein, S.5
-
82
-
-
0034080896
-
Subtractive hybridization of mRNA from early passage and senescent endothelial cells
-
DOI 10.1016/S0531-5565(00)00080-2, PII S0531556500000802
-
Grillari J, Hohenwarter O, Grabherr RM, Katinger H. Subtractive hybridization of mRNA from early passage and senescent endothelial cells. Exp Gerontol 2000;35:187-197. (Pubitemid 30190084)
-
(2000)
Experimental Gerontology
, vol.35
, Issue.2
, pp. 187-197
-
-
Grillari, J.1
Hohenwarter, O.2
Grabherr, R.M.3
Katinger, H.4
-
83
-
-
0030933120
-
Increased bronchoalveolar granulocytes and granulocyte/macrophage colony-stimulating factor during exacerbations of chronic bronchitis
-
Balbi B, Bason C, Balleari E, Fiasella F, Pesci A, Ghio R, Fabiano F. Increased bronchoalveolar granulocytes and granulocyte/macrophage colony-stimulating factor during exacerbations of chronic bronchitis. Eur Respir J 1997;10:846-850. (Pubitemid 27180197)
-
(1997)
European Respiratory Journal
, vol.10
, Issue.4
, pp. 846-850
-
-
Balbi, B.1
Bason, C.2
Balleari, E.3
Fiasella, F.4
Pesci, A.5
Ghio, R.6
Fabiano, F.7
-
84
-
-
0038575443
-
Extracellular matrix remodelling: The role of matrix metalloproteinases
-
DOI 10.1002/path.1400
-
Stamenkovic I. Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol 2003;200:448-464. (Pubitemid 36818245)
-
(2003)
Journal of Pathology
, vol.200
, Issue.4
, pp. 448-464
-
-
Stamenkovic, I.1
-
85
-
-
0024445960
-
Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity
-
DOI 10.1016/0014-4827(89)90372-8
-
West MD, Pereira-Smith OM, Smith JR. Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity. Exp Cell Res 1989;184:138-147. (Pubitemid 19233395)
-
(1989)
Experimental Cell Research
, vol.184
, Issue.1
, pp. 138-147
-
-
West, M.D.1
Pereira-Smith, O.M.2
Smith, J.R.3
-
86
-
-
0026793281
-
Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts
-
Millis AJ, Hoyle M, McCue HM, Martini H. Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts. Exp Cell Res 1992;201:373-379.
-
(1992)
Exp Cell Res
, vol.201
, pp. 373-379
-
-
Millis, A.J.1
Hoyle, M.2
McCue, H.M.3
Martini, H.4
-
87
-
-
0030042853
-
Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts
-
DOI 10.1006/excr.1996.0019
-
Zeng G, Millis AJ. Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts. Exp Cell Res 1996;222:150-156. (Pubitemid 26043720)
-
(1996)
Experimental Cell Research
, vol.222
, Issue.1
, pp. 150-156
-
-
Zeng, G.1
Millis, A.J.T.2
-
88
-
-
13944260728
-
Stromal-epithelial interactions in aging and cancer: Senescent fi broblasts alter epithelial cell differentiation
-
Parrinello S, Coppe JP, Krtolica A, Campisi J. Stromal-epithelial interactions in aging and cancer: senescent fi broblasts alter epithelial cell differentiation. J Cell Sci 2005;118:485 -496.
-
(2005)
J Cell Sci
, vol.118
, pp. 485-496
-
-
Parrinello, S.1
Coppe, J.P.2
Krtolica, A.3
Campisi, J.4
-
89
-
-
34248197982
-
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
-
DOI 10.1158/0008-5472.CAN-06-3452
-
Liu D, Hornsby PJ. Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion. Cancer Res 2007;67:3117-3126. (Pubitemid 46724848)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3117-3126
-
-
Liu, D.1
Hornsby, P.J.2
-
90
-
-
0030825320
-
Matrix metalloproteinase expression and production by alveolar macrophages in emphysema
-
Finlay GA, O'Driscoll LR, Russell KJ, D'Arcy EM, Masterson JB, FitzGerald MX, O'Connor CM. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med 1997;156:240-247. (Pubitemid 27293196)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.156
, Issue.1
, pp. 240-247
-
-
Finlay, G.A.1
O'Driscoll, L.R.2
Russell, K.J.3
D'Arcy, E.M.4
Masterson, J.B.5
Fitzgerald, M.X.6
O'Connor, C.M.7
-
91
-
-
0032989453
-
Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema
-
Betsuyaku T, Nishimura M, Takeyabu K, Tanino M, Venge P, Xu S, Kawakami Y. Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema. Am J Respir Crit Care Med 1999;159:1985-1991. (Pubitemid 29275073)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.6
, pp. 1985-1991
-
-
Betsuyaku, T.1
Nishimura, M.2
Takeyabu, K.3
Tanino, M.4
Venge, P.5
Xu, S.6
Kawakami, Y.7
-
92
-
-
0032696013
-
Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease
-
Culpitt SV, Maziak W, Loukidis S, Nightingale JA, Matthews JL, Barnes PJ. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:1635-1639.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1635-1639
-
-
Culpitt, S.V.1
Maziak, W.2
Loukidis, S.3
Nightingale, J.A.4
Matthews, J.L.5
Barnes, P.J.6
-
93
-
-
0033773688
-
Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers: Regulation by interleukin-10
-
Lim S, Roche N, Oliver BG, Mattos W, Barnes PJ, Chung KF. Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers: regulation by interleukin-10. Am J Respir Crit Care Med 2000;162:1355-1360.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1355-1360
-
-
Lim, S.1
Roche, N.2
Oliver, B.G.3
Mattos, W.4
Barnes, P.J.5
Chung, K.F.6
-
94
-
-
0036010527
-
Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease
-
Russell RE, Culpitt SV, DeMatos C, Donnelly L, Smith M, Wiggins J, Barnes PJ. Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2002;26:602-609. (Pubitemid 34315869)
-
(2002)
American Journal of Respiratory Cell and Molecular Biology
, vol.26
, Issue.5
, pp. 602-609
-
-
Russell, R.E.K.1
Culpitt, S.V.2
DeMatos, C.3
Donnelly, L.4
Smith, M.5
Wiggins, J.6
Barnes, P.J.7
-
95
-
-
0036783727
-
Alveolar macrophage-mediated elastolysis: Roles of matrix metalloproteinases, cysteine, and serine proteases
-
Russell RE, Thorley A, Culpitt SV, Dodd S, Donnelly LE, Demattos C, Fitzgerald M, Barnes PJ. Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases. Am J Physiol Lung Cell Mol Physiol 2002;283:L867-L873.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Russell, R.E.1
Thorley, A.2
Culpitt, S.V.3
Dodd, S.4
Donnelly, L.E.5
Demattos, C.6
Fitzgerald, M.7
Barnes, P.J.8
-
96
-
-
0033663165
-
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease
-
Cataldo D, Munaut C, Noël A, Frankenne F, Bartsch P, Foidart JM, Louis R. MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol 2000;123:259-267.
-
(2000)
Int Arch Allergy Immunol
, vol.123
, pp. 259-267
-
-
Cataldo, D.1
Munaut, C.2
Noël, A.3
Frankenne, F.4
Bartsch, P.5
Foidart, J.M.6
Louis, R.7
-
97
-
-
0037637437
-
Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects
-
DOI 10.1053/rmed.2003.1493
-
Beeh KM, Beier J, Kornmann O, Buhl R. Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1, and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects. Respir Med 2003;97:634-639. (Pubitemid 36675664)
-
(2003)
Respiratory Medicine
, vol.97
, Issue.6
, pp. 634-639
-
-
Beeh, K.M.1
Beier, J.2
Kornmann, O.3
Buhl, R.4
-
99
-
-
0029089162
-
Senescence-dependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells
-
Comi P, Chiaramonte R, Maier JA. Senescence-dependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells. Exp Cell Res 1995;219:304-308.
-
(1995)
Exp Cell Res
, vol.219
, pp. 304-308
-
-
Comi, P.1
Chiaramonte, R.2
Maier, J.A.3
-
100
-
-
0029962187
-
Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence
-
DOI 10.1016/0531-5565(95)02013-6
-
West MD, Shay JW, Wright WE, Linskens MH. Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence. Exp Gerontol 1996;31:175-193. (Pubitemid 26079671)
-
(1996)
Experimental Gerontology
, vol.31
, Issue.1-2
, pp. 175-193
-
-
West, M.D.1
Shay, J.W.2
Wright, W.E.3
Linskens, M.H.K.4
-
101
-
-
0029559374
-
Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts
-
DOI 10.1002/jcp.1041650324
-
Mu XC, Higgins PJ. Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts. J Cell Physiol 1995;165:647-657. (Pubitemid 26004323)
-
(1995)
Journal of Cellular Physiology
, vol.165
, Issue.3
, pp. 647-657
-
-
Mu, X.-C.1
Higgins, P.J.2
-
102
-
-
0031973050
-
Increased Transcription and Modified Growth State-Dependent Expression of the Plasminogen Activator Inhibitor Type-1 Gene Characterize the Senescent Phenotype in Human Diploid Fibroblasts
-
Mu XC, Staiano-Coico L, Higgins PJ. Increased transcription and modified growth state-dependent expression of the plasminogen activator inhibitor type-1 gene characterize the senescent phenotype in human diploid fibroblasts. J Cell Physiol 1998;174:90-98. (Pubitemid 128492436)
-
(1998)
Journal of Cellular Physiology
, vol.174
, Issue.1
, pp. 90-98
-
-
Mu, X.-C.1
Staiano-Coico, L.2
Higgins, P.J.3
-
103
-
-
0037329040
-
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression
-
Martens JW, Sieuwerts AM, Bolt-deVries J, Bosma PT, Swiggers SJ, Klijn JG, Foekens JA. Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression. Thromb Haemost 2003;89:393-404. (Pubitemid 36227292)
-
(2003)
Thrombosis and Haemostasis
, vol.89
, Issue.2
, pp. 393-404
-
-
Martens, J.W.M.1
Siewertz, A.M.2
Bolt-De, V.J.3
Bosma, P.T.4
Swiggers, S.J.J.5
Klijn, J.G.M.6
Foekens, J.A.7
-
104
-
-
77149162409
-
Higher levels of urokinase plasminogen activator system components in the airways of chronic obstructive pulmonary disease patients
-
in Chinese
-
Xiao W, Tong WL, Ma DD. Higher levels of urokinase plasminogen activator system components in the airways of chronic obstructive pulmonary disease patients [in Chinese]. Zhonghua Jie He He Hu Xi Za Zhi 2006;29:723-726.
-
(2006)
Zhonghua Jie He He Hu Xi Za Zhi
, vol.29
, pp. 723-726
-
-
Xiao, W.1
Tong, W.L.2
Ma, D.D.3
-
105
-
-
0028265386
-
Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis
-
Di Stefano A, Maestrelli P, Roggeri A, Turato G, Calabro S, Potena A, Mapp CE, Ciaccia A, Covacev L, Fabbri LM, et al. Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis. Am J Respir Crit Care Med 1994;149:803-810. (Pubitemid 24082245)
-
(1994)
American Journal of Respiratory and Critical Care Medicine
, vol.149
, Issue.3 I
, pp. 803-810
-
-
Di, S.A.1
Maestrelli, P.2
Roggeri, A.3
Turato, G.4
Calabro, S.5
Potena, A.6
Mapp, C.E.7
Ciaccia, A.8
Covacev, L.9
Fabbri, L.M.10
Saetta, M.11
-
106
-
-
0033193284
-
Role of adhesion molecules in the pathogenesis of COPD
-
in Japanese
-
Ishii Y. Role of adhesion molecules in the pathogenesis of COPD [in Japanese]. Nihon Rinsho 1999;57:1965-1971.
-
(1999)
Nihon Rinsho
, vol.57
, pp. 1965-1971
-
-
Ishii, Y.1
-
107
-
-
0036181715
-
Expression of adhesion molecules in allergic lung diseases
-
DOI 10.1007/s004280100507
-
Popper HH, Pailer S, Wurzinger G, Feldner H, Hesse C, Eber E. Expression of adhesion molecules in allergic lung diseases. Virchows Arch 2002;440:172-180. (Pubitemid 34169855)
-
(2002)
Virchows Archiv
, vol.440
, Issue.2
, pp. 172-180
-
-
Popper, H.H.1
Pailer, S.2
Wurzinger, G.3
Feldner, H.4
Hesse, C.5
Eber, E.6
-
108
-
-
79960418124
-
Osteoprotegerin in sputum is a potential biomarker in COPD
-
To M, Ito K, Ausin PM, Kharitonov SA, Barnes PJ. Osteoprotegerin in sputum is a potential biomarker in COPD. Chest 2011;140:76-83.
-
(2011)
Chest
, vol.140
, pp. 76-83
-
-
To, M.1
Ito, K.2
Ausin, P.M.3
Kharitonov, S.A.4
Barnes, P.J.5
-
109
-
-
33745600572
-
Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte
-
Lu SY, Chang KW, Liu CJ, Tseng YH, Lu HH, Lee SY, Lin SC. Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte. Carcinogenesis 2006;27:1273-1284.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1273-1284
-
-
Lu, S.Y.1
Chang, K.W.2
Liu, C.J.3
Tseng, Y.H.4
Lu, H.H.5
Lee, S.Y.6
Lin, S.C.7
-
110
-
-
0038015372
-
Exhaled leukotrienes and prostaglandins in COPD
-
DOI 10.1136/thorax.58.7.585
-
Montuschi P, Kharitonov SA, Ciabattoni G, Barnes PJ. Exhaled leukotrienes and prostaglandins in COPD. Thorax 2003;58:585-588. (Pubitemid 36808128)
-
(2003)
Thorax
, vol.58
, Issue.7
, pp. 585-588
-
-
Montuschi, P.1
Kharitonov, S.A.2
Ciabattoni, G.3
Barnes, P.J.4
-
111
-
-
0038755585
-
2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages
-
DOI 10.1023/A:1023495626568
-
Jiang YJ, Lu B, Choy PC, Hatch GM. Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages. Mol Cell Biochem 2003;246:31-38. (Pubitemid 36798719)
-
(2003)
Molecular and Cellular Biochemistry
, vol.246
, Issue.1-2
, pp. 31-38
-
-
Jiang, Y.J.1
Lu, B.2
Choy, P.C.3
Hatch, G.M.4
-
112
-
-
0034014278
-
Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease
-
Taha R, Olivenstein R, Utsumi T, Ernst P, Barnes PJ, Rodger IW, Giaid A. Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000;161:636-640. (Pubitemid 30129478)
-
(2000)
American Journal of Respiratory and Critical Care Medicine
, vol.161
, Issue.2 I
, pp. 636-640
-
-
Taha, R.1
Olivenstein, R.2
Utsumi, T.3
Ernst, P.4
Barnes, P.J.5
Rodger, I.W.6
Giaid, A.7
-
113
-
-
0028245337
-
Altered regulation of fibronectin gene expression in Werner syndrome fibroblasts
-
DOI 10.1006/excr.1994.1181
-
Rasoamanantena P, Thweatt R, Labat-Robert J, Goldstein S. Altered regulation of fi bronectin gene expression in Werner syndrome fibroblasts. Exp Cell Res 1994;213:121-127. (Pubitemid 24227391)
-
(1994)
Experimental Cell Research
, vol.213
, Issue.1
, pp. 121-127
-
-
Rasoamanantena, P.1
Thweatt, R.2
Labat-Robert, J.3
Goldstein, S.4
-
114
-
-
0027277014
-
Enhanced expression of fibronectin during in vivo cellular aging of human vascular endothelial cells and skin fibroblasts
-
DOI 10.1006/excr.1993.1103
-
Kumazaki T, Kobayashi M, Mitsui Y. Enhanced expression of fibronectin during in vivo cellular aging of human vascular endothelial cells and skin fibroblasts. Exp Cell Res 1993;205:396-402. (Pubitemid 23192148)
-
(1993)
Experimental Cell Research
, vol.205
, Issue.2
, pp. 396-402
-
-
Kumazaki, T.1
Kobayashi, M.2
Mitsui, Y.3
-
115
-
-
33750717856
-
Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease
-
DOI 10.1309/JC47-7FAE-L1YK-V54W
-
Kranenburg AR, Willems-Widyastuti A, Moori WJ, Sterk PJ, Alagappan VK, de Boer WI, Sharma HS. Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease. Am J Clin Pathol 2006;126:725-735. (Pubitemid 44707623)
-
(2006)
American Journal of Clinical Pathology
, vol.126
, Issue.5
, pp. 725-735
-
-
Kranenburg, A.R.1
Willems-Widyastuti, A.2
Mooi, W.J.3
Sterk, P.J.4
Alagappan, V.K.T.5
De Boer, W.I.6
Sharma, H.S.7
-
116
-
-
0027296739
-
Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell
-
DOI 10.1006/bbrc.1993.2153
-
Sato I, Morita I, Kaji K, Ikeda M, Nagao M, Murota S. Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell. Biochem Biophys Res Commun 1993;195:1070-1076. (Pubitemid 23280524)
-
(1993)
Biochemical and Biophysical Research Communications
, vol.195
, Issue.2
, pp. 1070-1076
-
-
Sato, I.1
Morita, I.2
Kaji, K.3
Ikeda, M.4
Nagao, M.5
Murota, S.6
-
117
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T, Yu ZX, Ferrans VJ, Howard BH, Finkel T. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 1999;274:7936-7940.
-
(1999)
J Biol Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
118
-
-
0034684652
-
Enhanced peroxynitrite formation is associated with vascular aging
-
van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, et al. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 2000;192:1731 -1744.
-
(2000)
J Exp Med
, vol.192
, pp. 1731-1744
-
-
Van Der Loo, B.1
Labugger, R.2
Skepper, J.N.3
Bachschmid, M.4
Kilo, J.5
Powell, J.M.6
Palacios-Callender, M.7
Erusalimsky, J.D.8
Quaschning, T.9
Malinski, T.10
-
119
-
-
0036566326
-
Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence
-
DOI 10.1093/emboj/21.9.2180
-
Macip S, Igarashi M, Fang L, Chen A, Pan ZQ, Lee SW, Aaronson SA. Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. EMBO J 2002;21:2180-2188. (Pubitemid 34516777)
-
(2002)
EMBO Journal
, vol.21
, Issue.9
, pp. 2180-2188
-
-
Macip, S.1
Igarashi, M.2
Fang, L.3
Chen, A.4
Pan, Z.-Q.5
Lee, S.W.6
Aaronson, S.A.7
-
120
-
-
0141763944
-
Senescence-enhanced oxidative stress is associated with deficiency of mitochondrial cytochrome c oxidase in vascular endothelial cells
-
DOI 10.1016/S0047-6374(03)00163-5
-
Xin MG, Zhang J, Block ER, Patel JM. Senescence-enhanced oxidative stress is associated with deficiency of mitochondrial cytochrome c oxidase in vascular endothelial cells. Mech Ageing Dev 2003;124:911-919. (Pubitemid 37138688)
-
(2003)
Mechanisms of Ageing and Development
, vol.124
, Issue.8-9
, pp. 911-919
-
-
Xin, M.-G.1
Zhang, J.2
Block, E.R.3
Patel, J.M.4
-
121
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
122
-
-
34547941973
-
The common biology of cancer and ageing
-
DOI 10.1038/nature05985, PII NATURE05985
-
Finkel T, Serrano M, Blasco MA. The common biology of cancer and ageing. Nature 2007;448:767-774. (Pubitemid 47266334)
-
(2007)
Nature
, vol.448
, Issue.7155
, pp. 767-774
-
-
Finkel, T.1
Serrano, M.2
Blasco, M.A.3
-
123
-
-
0035840849
-
Oxidative stress and lung inflammation in airways disease
-
DOI 10.1016/S0014-2999(01)01320-6, PII S0014299901013206
-
MacNee W. Oxidative stress and lung inflammation in airways disease. Eur J Pharmacol 2001;429:195-207. (Pubitemid 33043996)
-
(2001)
European Journal of Pharmacology
, vol.429
, Issue.1-3
, pp. 195-207
-
-
MacNee, W.1
-
124
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996;271:C1424-C1437.
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
125
-
-
80054696408
-
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice
-
Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, et al. Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice. Cell 2011;147:293-305.
-
(2011)
Cell
, vol.147
, pp. 293-305
-
-
Seimetz, M.1
Parajuli, N.2
Pichl, A.3
Veit, F.4
Kwapiszewska, G.5
Weisel, F.C.6
Milger, K.7
Egemnazarov, B.8
Turowska, A.9
Fuchs, B.10
-
126
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
DOI 10.1038/nature02789
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004;430:686-689. (Pubitemid 39061685)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 686-689
-
-
Wood, J.G.1
Regina, B.2
Lavu, S.3
Hewitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
127
-
-
84861831957
-
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
-
Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, et al. SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest 2012;122:2032-2045.
-
(2012)
J Clin Invest
, vol.122
, pp. 2032-2045
-
-
Yao, H.1
Chung, S.2
Hwang, J.W.3
Rajendrasozhan, S.4
Sundar, I.K.5
Dean, D.A.6
McBurney, M.W.7
Guarente, L.8
Gu, W.9
Rönty, M.10
-
128
-
-
84906854819
-
Endothelial progenitor cells in smokers are dysfunctional because of increased DNA damage and senescence
-
Paschalaki KE, Starke RD, Mercado N, Gorgoulis VG, Barnes PJ, Randi AM. Endothelial progenitor cells in smokers are dysfunctional because of increased DNA damage and senescence. Lancet 2013;381:S84.
-
(2013)
Lancet
, vol.381
-
-
Paschalaki, K.E.1
Starke, R.D.2
Mercado, N.3
Gorgoulis, V.G.4
Barnes, P.J.5
Randi, A.M.6
-
129
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
DOI 10.1038/nature06261, PII NATURE06261
-
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, et al . Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007;450:712-716. (Pubitemid 350207685)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
Jin, L.7
Boss, O.8
Perni, R.B.9
Vu, C.B.10
Bemis, J.E.11
Xie, R.12
Disch, J.S.13
Ng, P.Y.14
Nunes, J.J.15
Lynch, A.V.16
Yang, H.17
Galonek, H.18
Israelian, K.19
Choy, W.20
Iffland, A.21
Lavu, S.22
Medvedik, O.23
Sinclair, D.A.24
Olefsky, J.M.25
Jirousek, M.R.26
Elliott, P.J.27
Westphal, C.H.28
more..
-
130
-
-
84864010194
-
Glucocorticoids suppress selected components of the senescence-associated secretory phenotype
-
Laberge R-M, Zhou L, Sarantos MR, Rodier F, Freund A, de Keizer PLJ, Liu S, Demaria M, Cong Y-S, Kapahi P, et al. Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell 2012;11:569-578.
-
(2012)
Aging Cell
, vol.11
, pp. 569-578
-
-
Laberge, R.-M.1
Zhou, L.2
Sarantos, M.R.3
Rodier, F.4
Freund, A.5
De Keizer, P.L.J.6
Liu, S.7
Demaria, M.8
Cong, Y.-S.9
Kapahi, P.10
-
131
-
-
84906883353
-
COX inhibitors abolish senescence and related inflammation in COPD fi broblasts
-
abstract
-
Maylis D, Jean-Marie G, Sandra C, Marie-Claude B, Philippe C, Laurent B, Sophie H, Jean-Baptiste S, Pierre V, Jean Luc Dubois R, et al. COX inhibitors abolish senescence and related inflammation in COPD fi broblasts [abstract]. Am J Respir Crit Care Med 2013;187:A1097.
-
(2013)
Am J Respir Crit Care Med
, vol.187
-
-
Maylis, D.1
Jean-Marie, G.2
Sandra, C.3
Marie-Claude, B.4
Philippe, C.5
Laurent, B.6
Sophie, H.7
Jean-Baptiste, S.8
Pierre, V.9
Jean Luc Dubois, R.10
-
132
-
-
33744799127
-
Cytokines as targets in chronic obstructive pulmonary disease
-
DOI 10.2174/138945006777435263
-
Chung KF. Cytokines as targets in chronic obstructive pulmonary disease. Curr Drug Targets 2006;7:675-681. (Pubitemid 43827263)
-
(2006)
Current Drug Targets
, vol.7
, Issue.6
, pp. 675-681
-
-
Chung, K.F.1
-
133
-
-
0034043154
-
Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice
-
Korsgren M, Källström L, Uller L, Bjerke T, Sundler F, Persson CG, Korsgren O. Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice. Mediators Inflamm 2000;9:15-23. (Pubitemid 30399113)
-
(2000)
Mediators of Inflammation
, vol.9
, Issue.1
, pp. 15-23
-
-
Korsgren, M.1
Kallstrom, L.2
Uller, L.3
Bjerke, T.4
Sundler, F.5
Persson, C.G.A.6
Korsgren, O.7
-
134
-
-
0033020245
-
Epidermal growth factor system regulates mucin production in airways
-
DOI 10.1073/pnas.96.6.3081
-
Takeyama K, Dabbagh K, Lee HM, Agustí C, Lausier JA, Ueki IF, Grattan KM, Nadel JA. Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci USA 1999;96:3081-3086. (Pubitemid 29148847)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.6
, pp. 3081-3086
-
-
Takeyama, K.1
Dabbagh, K.2
Lee, H.-M.3
Agusti, C.4
Lausier, J.A.5
Ueki, I.F.6
Grattan, K.M.7
Nadel, J.A.8
-
135
-
-
0036846226
-
Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease
-
Kranenburg AR, De Boer WI, Van Krieken JH, Mooi WJ, Walters JE, Saxena PR, Sterk PJ, Sharma HS. Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2002;27:517-525. (Pubitemid 35301805)
-
(2002)
American Journal of Respiratory Cell and Molecular Biology
, vol.27
, Issue.5
, pp. 517-525
-
-
Kranenburg, A.R.1
De Boer, W.I.2
Van Krieken, J.H.J.M.3
Mooi, W.J.4
Walters, J.E.5
Saxena, P.R.6
Sterk, P.J.7
Sharma, H.S.8
-
136
-
-
33746616991
-
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
-
Kortlever RM, Higgins PJ, Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 2006;8:877-884.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 877-884
-
-
Kortlever, R.M.1
Higgins, P.J.2
Bernards, R.3
-
137
-
-
27144462218
-
Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation
-
DOI 10.1378/chest.128.4.2316
-
Xiao W, Hsu YP, Ishizaka A, Kirikae T, Moss RB. Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation. Chest 2005;128:2316-2326. (Pubitemid 41507575)
-
(2005)
Chest
, vol.128
, Issue.4
, pp. 2316-2326
-
-
Xiao, W.1
Hsu, Y.-P.2
Ishizaka, A.3
Kirikae, T.4
Moss, R.B.5
-
138
-
-
68949158393
-
Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells
-
Stewart CE, Sayers I. Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells. BMC Mol Biol 2009;10:75.
-
(2009)
BMC Mol Biol
, vol.10
, pp. 75
-
-
Stewart, C.E.1
Sayers, I.2
-
139
-
-
0021074445
-
Cathepsin B-like cysteine proteinase activity in sputum and immunohistologic identification of cathepsin B in alveolar macrophages
-
Burnett D, Crocker J, Stockley RA. Cathepsin B-like cysteine proteinase activity in sputum and immunohistologic identi fication of cathepsin B in alveolar macrophages. Am Rev Respir Dis 1983;128:915-919. (Pubitemid 14231349)
-
(1983)
American Review of Respiratory Disease
, vol.128
, Issue.5
, pp. 915-919
-
-
Burnett, D.1
Crocker, J.2
Stockley, R.A.3
-
140
-
-
33845478128
-
High ICAM-1 gene expression in pulmonary fibroblasts of COPD patients: A reflection of an enhanced immunological function
-
DOI 10.1183/09031936.06.00116205
-
Zandvoort A, van der Geld YM, Jonker MR, Noordhoek JA, Vos JT, Wesseling J, Kauffman HF, Timens W, Postma DS. High ICAM-1 gene expression in pulmonary fibroblasts of COPD patients: a reflection of an enhanced immunological function. Eur Respir J 2006;28:113-122. (Pubitemid 44914268)
-
(2006)
European Respiratory Journal
, vol.28
, Issue.1
, pp. 113-122
-
-
Zandvoort, A.1
Van Der Geld, Y.M.2
Jonker, M.R.3
Noordhoek, J.A.4
Vos, J.T.W.M.5
Wesseling, J.6
Kauffman, H.F.7
Timens, W.8
Postma, D.S.9
-
141
-
-
79960418124
-
Osteoprotegerin in sputum is a potential biomarker in COPD osteoprotegerin in COPD
-
To M, Ito K, Ausin PM, Kharitonov SA, Barnes PJ. Osteoprotegerin in sputum is a potential biomarker in COPD osteoprotegerin in COPD. Chest 2011;140:76-83.
-
(2011)
Chest
, vol.140
, pp. 76-83
-
-
To, M.1
Ito, K.2
Ausin, P.M.3
Kharitonov, S.A.4
Barnes, P.J.5
-
142
-
-
0034518719
-
Circulating levels of soluble Fas ligand and soluble Fas in patients with chronic obstructive pulmonary disease
-
DOI 10.1053/rmed.2000.0941
-
Takabatake N, Nakamura H, Inoue S, Terashita K, Yuki H, Kato S, Yasumura S, Tomoike H. Circulating levels of soluble Fas ligand and soluble Fas in patients with chronic obstructive pulmonary disease. Respir Med 2000;94:1215-1220. (Pubitemid 32049249)
-
(2000)
Respiratory Medicine
, vol.94
, Issue.12
, pp. 1215-1220
-
-
Takabatake, N.1
Nakamura, H.2
Inoue, S.3
Terashita, K.4
Yuki, H.5
Kato, S.6
Yasumura, S.7
Tomoike, H.8
-
144
-
-
0026461115
-
Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema
-
D'Armiento J, Dalal SS, Okada Y, Berg RA, Chada K. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell 1992;71:955-961.
-
(1992)
Cell
, vol.71
, pp. 955-961
-
-
D'Armiento, J.1
Dalal, S.S.2
Okada, Y.3
Berg, R.A.4
Chada, K.5
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