Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema

American Journal of Respiratory and Critical Care Medicine

Volumn 159, Issue 6, 1999, Pages 1985-1991

  Betsuyaku, Tomoko ^a,b   Nishimura, Masaharu ^a,b   Takeyabu, Kimihiro ^a,b   Tanino, Mishie ^a,b   Venge, Per ^a,b   Xu, Shengyuan ^a,b   Kawakami, Yoshikazu ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE B; LIPOCALIN; METALLOPROTEIN;

ADULT; AGED; ARTICLE; HUMAN; IMMUNOBLOTTING; LEUKOCYTE ACTIVATION; LUNG ALVEOLUS MACROPHAGE; LUNG EMPHYSEMA; LUNG LAVAGE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; ZYMOGRAPHY;

EID: 0032989453     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.159.6.9809043     Document Type: Article

References (32)

1. 1. Senior, R. M., and S. D. Shapiro. 1997. Chronic obstructive pulmonary disease: epidemiology, pathophysiology, and pathogenesis. In Fishman's Pulmonary Diseases and Disorders, 3rd ed. McGraw-Hill, New York, 659-681.
2. 2. Senior, R. M., and N. R. Anthonisen. 1998. Advances in pulmonary biology and medicine: chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 157:S139-S147.
3. 3. Stockley, R. A. 1998. Proteases/antiproteases: pathogenesis and role in therapy. Clin. Pulm. Med. 5: 203-210.
4. 4. Finkelstein, R., R. S. Fraser, H. Ghezzo, and M. G. Cosio. 1995. Alveolar inflammation and its relation to emphysema in smokers. Am. J. Respir. Crit. Care Med. 152:1666-1672.
5. 5. Yoshioka, A., T. Betsuyaku, M. Nishimura, K. Miyamoto, T. Kondo, and Y. Kawakami. 1995. Excessive neutrophil elastase in bronchoalveolar lavage fluid in subclinical emphysema. Am. J. Respir. Crit. Care Med. 152:2127-2132.
6. 6. Betsuyaku, T., M. Nishimura, A. Yoshioka, K. Takeyabu, K. Miyamoto, and Y. Kawakami. 1996. Elastin-derived peptides and neutrophil elastase in bronchoalveolar lavage fluid. Am. J. Respir. Crit. Care Med. 154:720-724.
7. 7. Borregaard, N., and J. B. Cowland. 1997. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 89:3503-3521.
8. 8. Kjeldsen, L., A. H. Johnsen, H. Sengelov, and N. Borregaard. 1993. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268:10425-10432.
9. 9. Xu, S., M. Carlson. A. Engstrom, R. Garcia, and C. G. B. Peterson. 1994. Purification and characterization of a human neutrophil lipocalin (HNL) from the secondary granules of human neutrophils. Scand. J. Clin. Lab. Invest. 54:365-476.
10. 10. Tetley, T. D. 1993. Proteinase imbalance: its role in lung disease. Thorax 48:560-565.
11. 11. O'Connor, C. M., and M. X. FitzGerald. 1994. Matrix metalloproteases and lung disease. Thorax 49:602-609.
12. 12. Tetley, T. D. 1997. Matrix metalloproteinases: a role in emphysema. Thorax 52:495.
13. 13. Vu, T. H., Z. Werb. 1998. Gelatinase B: structure, regulation, and function. In W. C. Parks and R. P. Mecham, editors. Matrix Metalloproteinases. Academic Press, San Diego, CA. 115-148.
14. 14. Hibbs, M. S., K. A. Hasty, J. M. Seyer, A. H. Kang, and C. L. Mainardi. 1985. Biochemical and immunological characterization of the secreted form of human neutrophil gelatinase. J. Biol. Chem. 260:2493-2500.
15. 15. Betsuyaku, T., A. Yoshioka, M. Nishimura, K. Miyamoto, T. Kondo, and Y. Kawakami. 1995. Neutrophil elastase associated with alveolar macrophages from older volunteers. Am. J. Respir. Crit. Care Med. 151: 436-442.
16. 16. Rennard, S. I., M. Ghafouri, A. B. Thompson, J. Linder, W. Vaughan, K. Jones, R. F. Eetl, K. Christensen, A. Prince, M. G. Stahl, and R. A. Robbins. 1990. Fractional processing of sequential bronchoalveolar lavage to separate bronchial and alveolar samples. Am. Rev. Respir. Dis. 141:208-217.
17. 17. Xu, S., C. G. B. Petersson, M. Carlson, and P. Venge. 1994. The development of an assay for human neutrophil lipocalin (HNL) to be used as a specific marker of neutrophil activity in vivo and vitro. J. Immunol. Methods 171:245-252.
18. 18. Fujimoto, N., N. Hosokawa, K. Iwata, T. Shinya, Y. Okada, and T. Hayakawa. 1994. A one-step sandwich enzyme immunoassay for inactive precursor and completed forms of human matrix metalloproteinase-9 (92 kDa gelatinase/typo IV collagenase, gelatinase B) using monoclonal antibodies. Clin. Chim. Acta 231:79-88.
19. 19. Matsuki, H., N. Fujimoto, K. Iwata, V. Knäuper, Y. Okada, and T. Hayakawa. 1996. A one-step sandwich enzyme immunoassay for human matrix metalloproteinase-R (neutrophil collagenase) using monoclonal antibodies. Clin. Chim. Acta 244:129-143.
20. 20. Hautamaki, R. D., D. K. Kobayashi, R. M. Senior, and S. D. Shapiro. 1997. Recuirement of macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277:2002-2004.
21. 21. Sevéus, L., K. Amin, C. G. B. Peterson, G. M. Roomans, and P. Venge. 1997. Human neutrophil lipocalin (HNL) is a specific granule constituent of the neutrophil granulocyte: studies in bronchial and lung parenchymal tissue and peripheral blood cells. Histochem. Cell Biol. 107: 423-432.
22. 22. Cowland, J. B., and N. Borregaard. 1997. Molecular characterisation and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans. Genomics 45:17-23.
23. 23. Kjeldsen, L., D. Bainton, H. Sengelov, and N. Borregaard. 1994. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 83:799-807.
24. 24. Keatings, V. M., and P. J. Barnes. 1997. Granulocyte activation markers in induced sputum in comparison between chronic obstructive pulmonary disease, asthma, and normal subjects. Am. J. Respir. Crit. Care Med. 155:449-453.
25. 25. Finlay, G. A., K. J. Russell, K. J. Mchon, E. M. D'arcy, J. B. Masterson, M. X. FitzGerald, and C. M. O'Connor. 1997. Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients. Thorax 52:502-506.
26. 26. Horwitz, A. L., A. J. Hance, and R. G. Crystal. 1977. Granulocyte collagenase: selective degradation of type I relative to type III collagen. Proc. Natl. Acad. Sci. U.S.A. 74:897-901.
27. 27. Hanemaaijer, R., T. Sorsa, Y. Konttinen, Y. Dings, M. Sutinen, H. Visser, V. W. M. van Hinsbergh, T. Helaakoski, T. Kainulainen, H. Rönka, H. Tschesche, and T. Salo. 1997. Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. J. Biol. Chem. 272:31504-31509.
28. 28. Sibille, Y., and H. Y. Reynolds. 1990. Macrophages and polymorphonuclear neutrophils in lung defense and injury. Am. Rev. Respir. Dis. 141: 471-501.
29. 29. Burnett, D., A. Chamba, S. L. Hill, and R. A. Stockley. 1987. Neutrophils from subjects with chronic obstructive lung disease show enchanced chemotaxis and extracellular proteolysis. Lancet 2:1043-1046.
30. 30. MacNee, W., B. Wiggs, A. S. Belzberg, and J. C. Hogg. 1989. The effect of cigarette smoking on neutrophil kinetics in human lungs. N. Engl. J. Med. 321:924-928.
31. 31. Klut, M. E., C. M. Doerschuk, S. F. V. Eden, A. R. Burns, and J. C. Hogg. 1993. Activation of neutrophils within pulmonary microvessels of rabbits exposed to cigarette smoke. Am. J. Respir. Cell Mol. Biol. 9:82-89.
32. 1. Am. J. Respir. Crit. Care Med. 153:A8222.