Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: Association with diseases, impact on receptor functions and potential use as diagnosis biomarkers

International Journal of Molecular Sciences

Volumn 15, Issue 8, 2014, Pages 13344-13371

  Caseley, Emily A ^a   Muench, Stephen P ^a   Roger, Sebastien ^b   Mao, Hong Ju ^c   Baldwin, Stephen A ^a   Jiang, Lin Hua ^a,d  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITÉ DE TOURS   (France)

^c SHANGHAI INSTITUTE OF MICROSYSTEM AND INFORMATION TECHNOLOGY   (China)

^d XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Disease association; Loss or gain of function mutation; NS SNP; P2RX; Structure function relationships

Indexed keywords

ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; INTERLEUKIN 1BETA; PURINERGIC P2X RECEPTOR; PURINERGIC P2X1 RECEPTOR; PURINERGIC P2X2 RECEPTOR; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X5 RECEPTOR; PURINERGIC P2X6 RECEPTOR; PURINERGIC P2X7 RECEPTOR;

ARTICLE; CARDIOVASCULAR RISK; CHILDHOOD DISEASE; CHRONIC PAIN; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEBRILE CONVULSION; FRACTURE; GENE MUTATION; GENETIC ASSOCIATION; HEARING IMPAIRMENT; HUMAN; MOOD DISORDER; MULTIPLE SCLEROSIS; NOCICEPTION; NON SYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISM; NONHUMAN; PROTEIN FUNCTION; PULSE PRESSURE; RECEPTOR GENE; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TOXOPLASMOSIS; TUBERCULOSIS; ANIMAL; GENETICS; HEARING LOSS; MACULAR DEGENERATION; METABOLISM; MOOD DISORDERS; PATHOLOGY; SEIZURES;

ANIMALS; BIOLOGICAL MARKERS; HEARING LOSS; HUMANS; MACULAR DEGENERATION; MOOD DISORDERS; MULTIPLE SCLEROSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, PURINERGIC P2X7; SEIZURES; TUBERCULOSIS;

EID: 84905216515     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150813344     Document Type: Article

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