Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia

Lancet

Volumn 360, Issue 9349, 2002, Pages 1935-1939

  Thunberg, Ulf ^a   Tobin, Gerard ^a   Johnson, Anna ^a   Söderberg, Ola ^a   Padyukov, Leonid ^b   Hultdin, Magnus ^c   Klareskog, Lars ^b   Enblad, Gunilla ^a   Sundström, Christer ^a   Roos, Göran ^c   Rosenquist, Richard ^a,d  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; PURINE P2X RECEPTOR;

ADULT; AGED; ALLELE; ARTICLE; CANCER PATIENT; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE MUTATION; GENETIC SCREENING; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RESTRICTION MAPPING; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0037079306     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(02)11917-9     Document Type: Article

References (24)

1. Matutes E., Owusu-Ankomah K., Morilla R., et al. The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL. Leukemia. 8:1994;1640-1645.
2. Rai K.R., Sawitsky A., Cronkite E.P., Chanana A.D., Levy R.N., Paternack B.S. Clinical staging of chronic lymphocytic leukemia. Blood. 46:1975;219-234.
3. Binet J.L., Auquier A., Dighiero G., et al. A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate analysis. Cancer. 48:1981;198-206.
4. Hamblin T.J., Davis Z., Gardiner A., Oscier D.G., Stevenson F.K. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 94:1999;1848-1854.
5. Damle R.N., Wasil T., Fais F., et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 94:1999;1840-1847.
6. Thunberg U., Johnson A., Roos G., et al. CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia. Blood. 97:2001;1892-1894.
7. H3-21 genes characterize a new subset of chronic lymphocytic leukemia. Blood. 99:2002;2262-2264.
8. Kröber A., Seiler T., Benner A., et al. VH mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood. 100:2002;1410-1416.
9. Hamblin T.J., Orchard J.A., Ibbotson R.E., et al. CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood. 99:2002;1023-1029.
10. Dohner H., Stilgenbauer S., Benner A., et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med. 343:2000;1910-1916.
11. Di Virgilio F., Chiozzi P., Ferrari D., et al. Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood. 97:2001;587-600.
12. Gu B.J., Zhang W., Worthington R.A., et al. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J Biol Chem. 276:2001;11135-11142.
13. Wiley J.S., Dau-Ung L.P., Gu B.J., et al. A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study. Lancet. 359:2002;1114-1119.
14. Rassendren F., Buell G.N., Virginio C., Collo G., North R.A., Surprenant A. The permeabilizing ATP receptor, P2X7: cloning and expression of a human cDNA. J Biol Chem. 272:1997;5482-5486.
15. Wiley J.S., Gargett C.E., Zhang W., Snook M.B., Jamieson G.P. Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X7 channel. Am J Physiol. 275:1998;C1224-1231.
16. Baricordi O.R., Ferrari D., Melchiorri L., et al. An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes. Blood. 87:1996;682-690.
17. Baricordi O.R., Melchiorri L., Adinolfi E., et al. Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor. J Biol Chem. 274:1999;33206-33208.
18. Adinolfi E., Melchiorri L., Falzoni S., et al. P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia. Blood. 99:2002;706-708.
19. Jaffe E.S., Harris N.L., Stein H., Vardiman J.W. WHO classification of tumours, Pathology and genetics of tumours of haematopoietic and lymphoid tissues. 2001;IARC Press, Lyon.
20. Li A.H., Rosenquist R., Forestier E., et al. Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia: a comparative polymerase chain reaction study using multiple sets of primers. Eur J Haematol. 63:1999;211-218.
21. Lefranc M.P., Giudicelli V., Ginestoux C., et al. IMGT, the international ImMunoGeneTics database. Nucleic Acids Res. 27:1999;209-212.
22. Shahbazi M., Pravica V., Nasreen N., et al. Association between functional polymorphism in the EGF gene and malignant melanoma. Lancet. 359:2002;397-401.
23. Bange J., Prechtl D., Cheburkin Y., et al. Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele. Cancer Res. 62:2002;840-847.
24. Krajinovic M., Costea I., Chiasson S. Polymorphism of the thymidylate synthase gene and outcome of acute lymphoblastic leukaemia. Lancet. 359:2002;1033-1034.