A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure

Hypertension

Volumn 58, Issue 6, 2011, Pages 1086-1092

  Stokes, Leanne ^a   Scurrah, Katrina ^b   Ellis, Justine A ^b,c   Cromer, Brett A ^b,d   Skarratt, Kristen K ^a   Gu, Ben J ^a   Harrap, Stephen B ^b   Wiley, James S ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^d RMIT UNIVERSITY   (Australia)

Author keywords

ATP; P2RX4; P2X4 receptor; Polymorphism; Pulse pressure; SNP

Indexed keywords

PURINERGIC P2X4 RECEPTOR;

ALLELE; ARTERY COMPLIANCE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; HYPERTENSION; INHERITANCE; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; PULSE PRESSURE;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; BLOOD PRESSURE; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE FREQUENCY; GENOTYPE; HUMANS; MODELS, MOLECULAR; NEW SOUTH WALES; PATCH-CLAMP TECHNIQUES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PURINERGIC P2X4; RECOMBINANT FUSION PROTEINS; VASCULAR RESISTANCE; ZEBRAFISH PROTEINS;

EID: 83155180250     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.176180     Document Type: Article

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