-
1
-
-
0021268289
-
Tumor progression, oncogenes and the evolution of metastatic phenotypic diversity
-
Nicolson, G. L. (1984). Tumor progression, oncogenes and the evolution of metastatic phenotypic diversity. Clinical and Experimental Metastasis, 2, 85-105.
-
(1984)
Clinical and Experimental Metastasis
, vol.2
, pp. 85-105
-
-
Nicolson, G.L.1
-
2
-
-
0025324197
-
Cellular interactions in metastasis
-
DOI 10.1007/BF00047586
-
Miller, F. R., & Heppner, G. H. (1990). Cellular interactions in metastasis. Cancer and Metastasis Reviews, 9, 21-34. (Pubitemid 20237641)
-
(1990)
Cancer and Metastasis Reviews
, vol.9
, Issue.1
, pp. 21-34
-
-
Miller, F.R.1
Heppner, G.H.2
-
3
-
-
46449130084
-
Tumor-microenvironment interactions: Dangerous liaisons
-
Witz, I. P. (2008). Tumor-microenvironment interactions: dangerous liaisons. Advances in Cancer Research, 100, 203-229.
-
(2008)
Advances in Cancer Research
, vol.100
, pp. 203-229
-
-
Witz, I.P.1
-
4
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
Nguyen, D. X., Bos, P. D., & Massague, J. (2009). Metastasis: from dissemination to organ-specific colonization. Nature Reviews Cancer, 9, 274-284.
-
(2009)
Nature Reviews Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
5
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce, J. A., & Pollard, J. W. (2009). Microenvironmental regulation of metastasis. Nature Reviews Cancer, 9, 239-252.
-
(2009)
Nature Reviews Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
6
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso, J. A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nature Reviews Cancer, 7, 834-846.
-
(2007)
Nature Reviews Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
7
-
-
46449115631
-
Contact interactions between cells that suppress neoplastic development: Can they also explain metastatic dormancy?
-
Rubin, H. (2008). Contact interactions between cells that suppress neoplastic development: can they also explain metastatic dormancy? Advances in Cancer Research, 100, 159-202.
-
(2008)
Advances in Cancer Research
, vol.100
, pp. 159-202
-
-
Rubin, H.1
-
8
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
Tammela, T., & Alitalo, K. (2010). Lymphangiogenesis: molecular mechanisms and future promise. Cell, 140, 460-476.
-
(2010)
Cell
, vol.140
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
10
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
DOI 10.1038/ni1013
-
Karkkainen, M. J., Haiko, P., Sainio, K., Partanen, J., Taipale, J., Petrova, T. V., et al. (2004). Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nature Immunology, 5, 74-80. (Pubitemid 38081471)
-
(2004)
Nature Immunology
, vol.5
, Issue.1
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
Betsholtz, C.11
Alitalo, K.12
-
11
-
-
34447258681
-
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
-
DOI 10.1002/jcb.21187
-
Fukumura, D., & Jain, R. K. (2007). Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. Journal of Cellular Biochemistry, 101, 937-949. (Pubitemid 47040874)
-
(2007)
Journal of Cellular Biochemistry
, vol.101
, Issue.4
, pp. 937-949
-
-
Fukumura, D.1
Jain, R.K.2
-
12
-
-
0016300146
-
History of the Pasteur effect and its pathobiology
-
Racker, E. (1974). History of the Pasteur effect and its pathobiology. Molecular and Cellular Biochemistry, 5, 17-23.
-
(1974)
Molecular and Cellular Biochemistry
, vol.5
, pp. 17-23
-
-
Racker, E.1
-
13
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
DOI 10.1038/nrc1478
-
Gatenby, R. A., & Gillies, R. J. (2004). Why do cancers have high aerobic glycolysis? Nature Reviews Cancer, 4, 891-899. (Pubitemid 39472955)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.11
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
14
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science, 324, 1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
15
-
-
84856364753
-
Is there a role for carbohydrate restriction in the treatment and prevention of cancer?
-
Klement, R. J., & Kämmerer, U. (2011). Is there a role for carbohydrate restriction in the treatment and prevention of cancer? Nutrition & Metabolism (London), 8, 75.
-
(2011)
Nutrition & Metabolism (London)
, vol.8
, pp. 75
-
-
Klement, R.J.1
Kämmerer, U.2
-
16
-
-
50149097983
-
Hypoxia, HIF1 and glucose metabolism in the solid tumour
-
Denko, N. C. (2008). Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nature Reviews Cancer, 8, 705-713.
-
(2008)
Nature Reviews Cancer
, vol.8
, pp. 705-713
-
-
Denko, N.C.1
-
17
-
-
57449087215
-
Is cancer a disease of abnormal cellular metabolism? New angles on an old idea
-
DeBerardinis, R. J. (2008). Is cancer a disease of abnormal cellular metabolism? New angles on an old idea. Genetics in Medicine, 10, 767-777.
-
(2008)
Genetics in Medicine
, vol.10
, pp. 767-777
-
-
DeBerardinis, R.J.1
-
18
-
-
81155126061
-
Lactate: A metabolic key player in cancer
-
Hirschhaeuser, F., Sattler, U. G., & Mueller-Klieser, W. (2011). Lactate: a metabolic key player in cancer. Cancer Research, 71(22), 6921-6925.
-
(2011)
Cancer Research
, vol.71
, Issue.22
, pp. 6921-6925
-
-
Hirschhaeuser, F.1
Sattler, U.G.2
Mueller-Klieser, W.3
-
19
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
DOI 10.1074/jbc.M202487200
-
Lu, H., Forbes, R. A., & Verma, A. (2002). Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. Journal of Biological Chemistry, 277, 23111-23115. (Pubitemid 34952134)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.26
, pp. 23111-23115
-
-
Lu, H.1
Forbes, R.A.2
Verma, A.3
-
20
-
-
0028805375
-
Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences
-
Ebert, B. L., Firth, J. D., & Ratcliffe, P. J. (1995). Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences. Journal of Biological Chemistry, 270(49), 29083-29089.
-
(1995)
Journal of Biological Chemistry
, vol.270
, Issue.49
, pp. 29083-29089
-
-
Ebert, B.L.1
Firth, J.D.2
Ratcliffe, P.J.3
-
21
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switchrequired for cellular adaptation to hypoxia
-
Kim, J. W., Tchernyshyov, I., Semenza, G. L., & Dang, C. V. (2006). HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switchrequired for cellular adaptation to hypoxia. Cell Metabolism, 3, 177-185.
-
(2006)
Cell Metabolism
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
22
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G. L., Jiang, B. H., Leung, S. W., Passantino, R., Concordet, J. P., Maire, P., et al. (1996). Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. Journal of Biological Chemistry, 271(51), 32529-32537.
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.51
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
-
23
-
-
84867422886
-
Cancer cell metabolism
-
Cairns, R. A., Harris, I., McCracken, S., & Mak, T. W. (2011). Cancer cell metabolism. Cold Spring Harbor Symposia on Quantitative Biology, 76, 299-311.
-
(2011)
Cold Spring Harbor Symposia on Quantitative Biology
, vol.76
, pp. 299-311
-
-
Cairns, R.A.1
Harris, I.2
McCracken, S.3
Mak, T.W.4
-
24
-
-
57449097020
-
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
-
Sonveaux, P., Vegran, F., Schroeder, T., Wergin, M. C., Verrax, J., Rabbani, Z. N., et al. (2008). Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. Journal of Clinical Investigation, 118, 3930-3942.
-
(2008)
Journal of Clinical Investigation
, vol.118
, pp. 3930-3942
-
-
Sonveaux, P.1
Vegran, F.2
Schroeder, T.3
Wergin, M.C.4
Verrax, J.5
Rabbani, Z.N.6
-
25
-
-
69949124867
-
Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
-
Feron, O. (2009). Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiotherapy and Oncology, 92, 329-333.
-
(2009)
Radiotherapy and Oncology
, vol.92
, pp. 329-333
-
-
Feron, O.1
-
26
-
-
79957922046
-
Evidence for a stromal-epithelial 'lactate shuttle' in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts
-
Whitaker-Menezes, D., Martinez-Outschoorn, U. E., Lin, Z., Ertel, A., Flomenberg, N., Witkiewicz, A. K., et al. (2011). Evidence for a stromal-epithelial 'lactate shuttle' in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts. Cell Cycle, 10, 1772-1783.
-
(2011)
Cell Cycle
, vol.10
, pp. 1772-1783
-
-
Whitaker-Menezes, D.1
Martinez-Outschoorn, U.E.2
Lin, Z.3
Ertel, A.4
Flomenberg, N.5
Witkiewicz, A.K.6
-
27
-
-
71249103087
-
Cell-cell and intracellular lactate shuttles
-
Brooks, G. A. (2009). Cell-cell and intracellular lactate shuttles. Journal of Physiology, 587, 5591-5600.
-
(2009)
Journal of Physiology
, vol.587
, pp. 5591-5600
-
-
Brooks, G.A.1
-
28
-
-
4043110513
-
Lactate metabolism: A new paradigm for the third millennium
-
Gladden, L. B. (2004). Lactate metabolism: a new paradigm for the third millennium. Journal of Physiology, 558, 5-30.
-
(2004)
Journal of Physiology
, vol.558
, pp. 5-30
-
-
Gladden, L.B.1
-
29
-
-
84865335195
-
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with "Warburg- like" cancer metabolism and L-lactate production
-
Guido, C., Whitaker-Menezes, D., Capparelli, C., Balliet, R., Lin, Z., Pestell, R. G., et al. (2012). Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle, 11(16), 3019-3035.
-
(2012)
Cell Cycle
, vol.11
, Issue.16
, pp. 3019-3035
-
-
Guido, C.1
Whitaker-Menezes, D.2
Capparelli, C.3
Balliet, R.4
Lin, Z.5
Pestell, R.G.6
-
30
-
-
84867112200
-
Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay
-
Fiaschi, T., Marini, A., Giannoni, E., Taddei, M. L., Gandellini, P., De Donatis, A., et al. (2012). Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay. Cancer Research, 72, 5130-5140.
-
(2012)
Cancer Research
, vol.72
, pp. 5130-5140
-
-
Fiaschi, T.1
Marini, A.2
Giannoni, E.3
Taddei, M.L.4
Gandellini, P.5
De Donatis, A.6
-
32
-
-
84883182637
-
Disrupting proton dynamics and energy metabolism for cancer therapy
-
Parks, S. K., Chiche, J., & Pouysségur, J. (2013). Disrupting proton dynamics and energy metabolism for cancer therapy. Nature Reviews Cancer, 13(9), 611-623.
-
(2013)
Nature Reviews Cancer
, vol.13
, Issue.9
, pp. 611-623
-
-
Parks, S.K.1
Chiche, J.2
Pouysségur, J.3
-
33
-
-
84865963556
-
Extracellular acidity as favouring factor of tumor progression and metastatic dissemination
-
Calorini, L., Peppicelli, S., & Bianchini, F. (2012). Extracellular acidity as favouring factor of tumor progression and metastatic dissemination. Experimental Oncology, 34(2), 79-84.
-
(2012)
Experimental Oncology
, vol.34
, Issue.2
, pp. 79-84
-
-
Calorini, L.1
Peppicelli, S.2
Bianchini, F.3
-
34
-
-
0034652620
-
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
-
Walenta, S., Wetterling, M., Lehrke, M., Schwickert, G., Sundfør, K., Rofstad, E. K., et al. (2000). High lactate levels predict likelihood ofmetastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Research, 60, 916-921. (Pubitemid 30129526)
-
(2000)
Cancer Research
, vol.60
, Issue.4
, pp. 916-921
-
-
Walenta, S.1
Wetterling, M.2
Lehrke, M.3
Schwickert, G.4
Sundfor, K.5
Rofstad, E.K.6
Mueller-Klieser, W.7
-
35
-
-
0026623304
-
Clastogenicity of low pH to various cultured mammalian cells
-
Morita, T., Nagaki, T., Fukuda, I., & Okumura, K. (1992). Clastogenicity of low pH to various cultured mammalian cells. Mutation Research, 268, 297-305.
-
(1992)
Mutation Research
, vol.268
, pp. 297-305
-
-
Morita, T.1
Nagaki, T.2
Fukuda, I.3
Okumura, K.4
-
36
-
-
0034884690
-
Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone
-
DOI 10.1038/sj.neo.7900151
-
Raghunand, N., Mahoney, B., van Sluis, R., Baggett, B., & Gillies, R. J. (2001). Acute metabolic alkalosis enhances response of C3H mousemammary tumors to the weak basemitoxantrone. Neoplasia, 3, 227-235. (Pubitemid 32747571)
-
(2001)
Neoplasia
, vol.3
, Issue.3
, pp. 227-235
-
-
Raghunand, N.1
Mahoney, B.2
Van Sluis, R.3
Baggett, B.4
Gillies, R.J.5
-
37
-
-
0019964896
-
Radioresistance secondary to low pH in human glial cells and Chinese hamster ovary cells
-
Rottinger, E. M., & Mendonca, M. (1982). Radioresistance secondary to low pH in human glial cells and Chinese hamster ovary cells. International Journal of Radiation Oncology, Biology, and Physics, 8, 1309-1314. (Pubitemid 12031979)
-
(1982)
International Journal of Radiation Oncology Biology Physics
, vol.8
, Issue.8
, pp. 1309-1314
-
-
Rottinger, E.M.1
Mendonca, M.2
-
38
-
-
81155159685
-
Dysregulated pH: A perfect storm for cancer progression
-
Webb, B. A., Chimenti, M., Jacobson, M. P., & Barber, D. L. (2011). Dysregulated pH: a perfect storm for cancer progression. Nature Reviews Cancer, 11, 671-677.
-
(2011)
Nature Reviews Cancer
, vol.11
, pp. 671-677
-
-
Webb, B.A.1
Chimenti, M.2
Jacobson, M.P.3
Barber, D.L.4
-
39
-
-
34548038993
-
Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis
-
DOI 10.1158/0008-5472.CAN-06-3459
-
Provent, P., Benito, M., Hiba, B., Farion, R., López-Larrubia, P., Ballesteros, P., et al. (2007). Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis. Cancer Research, 67, 7638-7645. (Pubitemid 47281356)
-
(2007)
Cancer Research
, vol.67
, Issue.16
, pp. 7638-7645
-
-
Provent, P.1
Benito, M.2
Hiba, B.3
Farion, R.4
Lopez-Larrubia, P.5
Ballesteros, P.6
Remy, C.7
Segebarth, C.8
Cerdan, S.9
Coles, J.A.10
Garcia-Martin, M.L.11
-
40
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
DOI 10.1038/nature04871, PII NATURE04871
-
Pouyssegur, J., Dayan, F., & Mazure, N. M. (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature, 441, 437-443. (Pubitemid 44050138)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
41
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
DOI 10.1038/nm0297-177
-
Helmlinger, G., Yuan, F., Dellian, M., & Jain, R. K. (1997). Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nature Medicine, 3, 177-182. (Pubitemid 27064702)
-
(1997)
Nature Medicine
, vol.3
, Issue.2
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
42
-
-
0344305784
-
Cell Migration: Integrating Signals from Front to Back
-
DOI 10.1126/science.1092053
-
Ridley, A. J., Schwartz, M. A., Burridge, K., Firtel, R. A., Ginsberg, M. H., Borisy, G., et al. (2003). Cell migration: integrating signals from front to back. Science, 302, 1704-1709. (Pubitemid 37505725)
-
(2003)
Science
, vol.302
, Issue.5651
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
Borisy, G.6
Parsons, J.T.7
Horwitz, A.R.8
-
43
-
-
1042289739
-
Solution structure of human cofilin. Actin binding, pH sensitivity, and relationship to actin-depolymerizing factor
-
DOI 10.1074/jbc.M310148200
-
Pope, B. J., Zierler-Gould, K. M., Kühne, R., Weeds, A. G., & Ball, L. J. (2004). Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor. Journal of Biological Chemistry, 279(6), 4840-4848. (Pubitemid 38199079)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4840-4848
-
-
Pope, B.J.1
Zierler-Gould, K.M.2
Kuhne, R.3
Weeds, A.G.4
Ball, L.J.5
-
44
-
-
34250199732
-
Acid-induced equilibrium folding intermediate of human platelet profilin
-
DOI 10.1021/bi0602359
-
McLachlan, G. D., Cahill, S. M., Girvin, M. E., & Almo, S. C. (2007). Acid-induced equilibrium folding intermediate of human platelet profiling. Biochemistry, 46, 6931-6943. (Pubitemid 46906422)
-
(2007)
Biochemistry
, vol.46
, Issue.23
, pp. 6931-6943
-
-
McLachlan, G.D.1
Cahill, S.M.2
Girvin, M.E.3
Almo, S.C.4
-
45
-
-
33646704772
-
Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo
-
DOI 10.1242/jcs.02860
-
Moseley, J. B., Okada, K., Balcer, H. I., Kovar, D. R., Pollard, T. D., & Goode, B. L. (2006). Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo. Journal of Cell Science, 119, 1547-1557. (Pubitemid 43732981)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.8
, pp. 1547-1557
-
-
Moseley, J.B.1
Okada, K.2
Balcer, H.I.3
Kovar, D.R.4
Pollard, T.D.5
Goode, B.L.6
-
46
-
-
29444454319
-
Characterizing a partially folded intermediate of the villin headpiece domain under non-denaturing conditions: Contribution of His41 to the pH-dependent stability of the N-terminal subdomain
-
DOI 10.1016/j.jmb.2005.11.001, PII S0022283605013641
-
Grey, M. J., Tang, Y., Alexov, E., McKnight, C. J., Raleigh, D. P., & Palmer, A. G., III. (2006). Characterizing a partially folded intermediate of the villin headpiece domain under non-denaturing conditions: contribution of His41 to the pH dependent stability of the N-terminal subdomain. Journal of Molecular Biology, 355, 1078-1094. (Pubitemid 43012149)
-
(2006)
Journal of Molecular Biology
, vol.355
, Issue.5
, pp. 1078-1094
-
-
Grey, M.J.1
Tang, Y.2
Alexov, E.3
McKnight, C.J.4
Raleigh, D.P.5
Palmer III, A.G.6
-
47
-
-
55749092149
-
Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling
-
Srivastava, J., Barreiro, G., Groscurth, S., Gingras, A. R., Goult, B. T., Critchley, D. R., et al. (2008). Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling. Proceedings of the National Academy of Sciences of the United States of America, 105, 14436-14441.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 14436-14441
-
-
Srivastava, J.1
Barreiro, G.2
Groscurth, S.3
Gingras, A.R.4
Goult, B.T.5
Critchley, D.R.6
-
48
-
-
35949000834
-
+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells
-
DOI 10.1083/jcb.200704169
-
Frantz, C., Karydis, A., Nalbant, P., Hahn, K. M., & Barber, D. L. (2007). Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells. The Journal of Cell Biology, 179, 403-410. (Pubitemid 350074786)
-
(2007)
Journal of Cell Biology
, vol.179
, Issue.3
, pp. 403-410
-
-
Frantz, C.1
Karydis, A.2
Nalbant, P.3
Hahn, K.M.4
Barber, D.L.5
-
49
-
-
49049086915
-
Protons extruded by NHE1: Digestive or glue?
-
Stock, C., Cardone, R. A., Busco, G., Krähling, H., Schwab, A., & Reshkin, S. J. (2008). Protons extruded by NHE1: digestive or glue? European Journal of Cell Biology, 87, 591-599.
-
(2008)
European Journal of Cell Biology
, vol.87
, pp. 591-599
-
-
Stock, C.1
Cardone, R.A.2
Busco, G.3
Krähling, H.4
Schwab, A.5
Reshkin, S.J.6
-
50
-
-
79251633163
-
Acidic extracellular pH promotes activation of integrin αvβ3
-
Paradise, R. K., Lauffenburger, D. A., & Van Vliet, K. J. (2011). Acidic extracellular pH promotes activation of integrin αvβ3. PLoS ONE, 6, e15746.
-
(2011)
PLoS ONE
, vol.6
-
-
Paradise, R.K.1
Lauffenburger, D.A.2
Van Vliet, K.J.3
-
51
-
-
84867405330
-
pH regulators in invadosomal functioning: Proton delivery for matrix tasting
-
Brisson, L., Reshkin, S. J., Goré, J., & Roger, S. (2012). pH regulators in invadosomal functioning: proton delivery for matrix tasting. European Journal of Cell Biology, 91, 847-860.
-
(2012)
European Journal of Cell Biology
, vol.91
, pp. 847-860
-
-
Brisson, L.1
Reshkin, S.J.2
Goré, J.3
Roger, S.4
-
52
-
-
84455170179
-
Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK)
-
Lucien, F., Brochu-Gaudreau, K., Arsenault, D., Harper, K., & Dubois, C. M. (2011). Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK). PLoS One, 6, e28851.
-
(2011)
PLoS One
, vol.6
-
-
Lucien, F.1
Brochu-Gaudreau, K.2
Arsenault, D.3
Harper, K.4
Dubois, C.M.5
-
53
-
-
79151480835
-
Novel invadopodia components revealed by differential proteomic analysis
-
Attanasio, F., Caldieri, G., Giacchetti, G., van Horssen, R., Wieringa, B., & Buccione, R. (2011). Novel invadopodia components revealed by differential proteomic analysis. European Journal of Cell Biology, 90, 115-127.
-
(2011)
European Journal of Cell Biology
, vol.90
, pp. 115-127
-
-
Attanasio, F.1
Caldieri, G.2
Giacchetti, G.3
Van Horssen, R.4
Wieringa, B.5
Buccione, R.6
-
54
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin, J., Sameni, M., Ziegler, G., & Sloane, F. B. (1994). Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Research, 54, 6517-6525.
-
(1994)
Cancer Research
, vol.54
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, F.B.4
-
55
-
-
0033380522
-
Alterations in proteolytic activity at low pH and its association with invasion: A theoretical model
-
DOI 10.1023/A:1006667303583
-
Webb, S. D., Sherratt, J. A., & Fish, R. G. (1999). Alterations in proteolytic activity at low pH and its association with invasion: a theoretical model. Clinical and Experimental Metastasis, 17, 397-407. (Pubitemid 30019997)
-
(1999)
Clinical and Experimental Metastasis
, vol.17
, Issue.5
, pp. 397-407
-
-
Webb, S.D.1
Sherratt, J.A.2
Fish, R.G.3
-
56
-
-
0026516022
-
Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L
-
Goretzki, L., Schmitt, M., Mann, K., Calvete, J., Chucholowski, N., Kramer, M., et al. (1992). Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L. FEBS Letters, 297, 112-118.
-
(1992)
FEBS Letters
, vol.297
, pp. 112-118
-
-
Goretzki, L.1
Schmitt, M.2
Mann, K.3
Calvete, J.4
Chucholowski, N.5
Kramer, M.6
-
57
-
-
0029943568
-
Plasminogen activators and matrix metalloproteinases in angiogenesis
-
Mignatti, P., & Rifkin, D. B. (1996). Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme and Protein, 49, 117-137. (Pubitemid 26181742)
-
(1996)
Enzyme and Protein
, vol.49
, Issue.1-3
, pp. 117-137
-
-
Mignatti, P.1
Rifkin, D.B.2
-
58
-
-
0023916551
-
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium
-
Lyons, R. M., Keski-Oja, J., & Moses, H. L. (1988). Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. Journal of Cell Biology, 106, 1659-1665.
-
(1988)
Journal of Cell Biology
, vol.106
, pp. 1659-1665
-
-
Lyons, R.M.1
Keski-Oja, J.2
Moses, H.L.3
-
59
-
-
0027076170
-
The urokinase receptor: Involvement in cell surface proteolysis and cancer invasion
-
DOI 10.1111/j.1749-6632.1992.tb51591.x
-
Ellis, V., Pyke, C., Eriksen, J., Solberg, H., & Danø, K. (1992). The urokinase receptor: involvement in cell surface proteolysis and cancer invasion. Annals of the New York Academy of Sciences, 667, 13-31. (Pubitemid 23061557)
-
(1992)
Annals of the New York Academy of Sciences
, vol.667
, pp. 13-31
-
-
Ellis, V.1
Pyke, C.2
Eriksen, J.3
Solberg, H.4
Dano, K.5
-
60
-
-
0033618337
-
Matrix metalloproteinases
-
Nagase, H., & Woessner, J. F. (1999). Matrix metalloproteinases. Journal of Biological Chemistry, 274, 21491-21494. (Pubitemid 129519680)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.31
, pp. 21491-21494
-
-
Nagase, H.1
Woessner Jr., J.F.2
-
61
-
-
0037052641
-
Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets
-
DOI 10.1002/ijc.10329
-
Vihinen, P., & Kähäri, V. M. (2002). Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. International Journal of Cancer, 99(2), 157-166. (Pubitemid 34309470)
-
(2002)
International Journal of Cancer
, vol.99
, Issue.2
, pp. 157-166
-
-
Vihinen, P.1
Kahari, V.-M.2
-
62
-
-
0032789885
-
Experimental metastasis is suppressed in MMP-9-deficient mice
-
DOI 10.1023/A:1006603723759
-
Itoh, T., Tanioka, M., Matsuda, H., Nishimoto, H., Yoshioka, T., Suzuki, R., et al. (1999). Experimental metastasis is suppressed in MMP-9-deficient mice. Clinical and Experimental Metastasis, 17(2), 177-181. (Pubitemid 29335445)
-
(1999)
Clinical and Experimental Metastasis
, vol.17
, Issue.2
, pp. 177-181
-
-
Itoh, T.1
Tanioka, M.2
Matsuda, H.3
Nishimoto, H.4
Yoshioka, T.5
Suzuki, R.6
Uchira, M.7
-
63
-
-
0032031861
-
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice
-
Itoh, T., Tanioka, M., Yoshida, H., Yoshioka, T., Nishimoto, H., & Itohara, S. (1998). Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Research, 58(5), 1048-1051. (Pubitemid 28182477)
-
(1998)
Cancer Research
, vol.58
, Issue.5
, pp. 1048-1051
-
-
Itoh, T.1
Tanioka, M.2
Yoshida, H.3
Yoshioka, T.4
Nishimoto, H.5
Itohara, S.6
-
64
-
-
0026667311
-
Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines
-
Kato, Y., Nakayama, Y., Umeda, M., & Miyazaki, K. (1992). Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines. Journal of Biological Chemistry, 267(16), 11424-11430.
-
(1992)
Journal of Biological Chemistry
, vol.267
, Issue.16
, pp. 11424-11430
-
-
Kato, Y.1
Nakayama, Y.2
Umeda, M.3
Miyazaki, K.4
-
65
-
-
0033588093
-
Human heparanase. Purification, characterization, cloning, and expression
-
Toyoshima, M., & Nakajima, M. (1999). Human heparanase. Purification, characterization, cloning, and expression. Journal of Biological Chemistry, 274, 24153-24160.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 24153-24160
-
-
Toyoshima, M.1
Nakajima, M.2
-
66
-
-
0035927544
-
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells
-
DOI 10.1038/sj.onc.1204500
-
Shi, Q., Le, X., Wang, B., Abbruzzese, J. L., Xiong, Q., He, Y., et al. (2001). Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. Oncogene, 20, 3751-3756. (Pubitemid 32624967)
-
(2001)
Oncogene
, vol.20
, Issue.28
, pp. 3751-3756
-
-
Shi, Q.1
Le, X.2
Wang, B.3
Abbruzzese, J.L.4
Xiong, Q.5
He, Y.6
Xie, K.7
-
67
-
-
0035881307
-
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo
-
Fukumura, D., Xu, L., Chen, Y., Gohongi, T., Seed, B., & Jain, R. K. (2000). Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Research, 61, 6020-6024.
-
(2000)
Cancer Research
, vol.61
, pp. 6020-6024
-
-
Fukumura, D.1
Xu, L.2
Chen, Y.3
Gohongi, T.4
Seed, B.5
Jain, R.K.6
-
68
-
-
0034662635
-
Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells
-
Xu, L., & Fidler, I. J. (2000). Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells. Cancer Research, 60(16), 4610-4616. (Pubitemid 32103647)
-
(2000)
Cancer Research
, vol.60
, Issue.16
, pp. 4610-4616
-
-
Xu, L.1
Fidler, I.J.2
-
69
-
-
84890430472
-
Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells
-
Peppicelli, S., Bianchini, F., Contena, C., Tombaccini, D., & Calorini, L. (2013). Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells. Clinical and Experimental Metastasis, 30(8), 957-967.
-
(2013)
Clinical and Experimental Metastasis
, vol.30
, Issue.8
, pp. 957-967
-
-
Peppicelli, S.1
Bianchini, F.2
Contena, C.3
Tombaccini, D.4
Calorini, L.5
-
70
-
-
33644822574
-
The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells
-
Su, J. L., Yang, P. C., Shih, J. Y., Yang, C. Y., Wei, L. H., Hsieh, C. Y., et al. (2006). The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell, 9, 209-223.
-
(2006)
Cancer Cell
, vol.9
, pp. 209-223
-
-
Su, J.L.1
Yang, P.C.2
Shih, J.Y.3
Yang, C.Y.4
Wei, L.H.5
Hsieh, C.Y.6
-
71
-
-
27644473229
-
Epithelial-mesenchymal transition
-
Radisky, D. C. (2005). Epithelial-mesenchymal transition. Journal of Cell Science, 118(Pt 19), 4325-4326.
-
(2005)
Journal of Cell Science
, vol.118
, Issue.PART 19
, pp. 4325-4326
-
-
Radisky, D.C.1
-
72
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
DOI 10.1172/JCI200320530
-
Kalluri, R., & Neilson, E. G. (2003). Epithelial-mesenchymal transition and its implications for fibrosis. The Journal of Clinical Investigation, 112(12), 1776-1784. (Pubitemid 38063698)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
73
-
-
67651005404
-
EMT: When epithelial cells decide to become mesenchymal-like cells
-
Kalluri, R. (2009). EMT: when epithelial cells decide to become mesenchymal-like cells. The Journal of Clinical Investigation, 119(6), 1417-1419.
-
(2009)
The Journal of Clinical Investigation
, vol.119
, Issue.6
, pp. 1417-1419
-
-
Kalluri, R.1
-
74
-
-
84898596660
-
Contribution of acidic melanoma cells undergoing epithelial-to- mesenchymal transition to aggressiveness of non-acidic melanoma cells
-
Peppicelli, S., Bianchini, F., Torre, E., Calorini, L. (2014). Contribution of acidic melanoma cells undergoing epithelial-to-mesenchymal transition to aggressiveness of non-acidic melanoma cells. Clinical and Experimental Metastasis.
-
(2014)
Clinical and Experimental Metastasis
-
-
Peppicelli, S.1
Bianchini, F.2
Torre, E.3
Calorini, L.4
-
75
-
-
0031577714
-
Low extracellular pH induces activation of ERK 2, JNK, and p38 in A431 and Swiss 3T3 cells
-
DOI 10.1006/bbrc.1997.7759
-
Xue, L., & Lucocq, J. M. (1997). Low extracellular pH induces activation of ERK 2, JNK, and p38 in A431 and Swiss 3 T3 cells. Biochemical and Biophysical Research Communications, 241(2), 236-242. (Pubitemid 28020086)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.241
, Issue.2
, pp. 236-242
-
-
Xue, L.1
Lucocq, J.M.2
-
76
-
-
27644439083
-
- exchanger
-
DOI 10.1152/ajpgi.00215.2005
-
Sarosi, G. A., Jr., Jaiswal, K., Herndon, E., Lopez-Guzman, C., Spechler, S. J., & Souza, R. F. (2005). Acid increases MAPK-mediated proliferation in Barrett's esophageal adenocarcinoma cells via intracellular acidification through a Cl-/HCO3- exchanger. American Journal of Physiology - Gastrointestinal and Liver Physiology, 289(6), G991-G997. (Pubitemid 41740602)
-
(2005)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.289
, Issue.6
-
-
Sarosi Jr., G.A.1
Jaiswal, K.2
Herndon, E.3
Lopez-Guzman, C.4
Spechler, S.J.5
Souza, R.F.6
-
77
-
-
54049087754
-
Acidic preconditioning suppresses apoptosis and increases expression of Bcl-xL in coronary endothelial cells under simulated ischaemia
-
Kumar, S., Reusch, H. P., & Ladilov, Y. (2008). Acidic preconditioning suppresses apoptosis and increases expression of Bcl-xL in coronary endothelial cells under simulated ischaemia. Journal of Cellular and Molecular Medicine, 12(5A), 1584-1592.
-
(2008)
Journal of Cellular and Molecular Medicine
, vol.12
, Issue.5 A
, pp. 1584-1592
-
-
Kumar, S.1
Reusch, H.P.2
Ladilov, Y.3
-
78
-
-
84864974250
-
Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: Involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk
-
Ryder, C., McColl, K., Zhong, F., & Distelhorst, C. W. (2012). Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. Journal of Biological Chemistry, 287(33), 27863-27875.
-
(2012)
Journal of Biological Chemistry
, vol.287
, Issue.33
, pp. 27863-27875
-
-
Ryder, C.1
McColl, K.2
Zhong, F.3
Distelhorst, C.W.4
-
79
-
-
84865147552
-
Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments
-
Wojtkowiak, J. W., Rothberg, J. M., Kumar, V., Schramm, K. J., Haller, E., Proemsey, J. B., et al. (2012). Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Research, 72(16), 3938-3947.
-
(2012)
Cancer Research
, vol.72
, Issue.16
, pp. 3938-3947
-
-
Wojtkowiak, J.W.1
Rothberg, J.M.2
Kumar, V.3
Schramm, K.J.4
Haller, E.5
Proemsey, J.B.6
-
80
-
-
34250864795
-
Protein turnover via autophagy: Implications for metabolism
-
DOI 10.1146/annurev.nutr.27.061406.093749
-
Mizushima, N., & Klionsky, D. J. (2007). Protein turnover via autophagy: implications for metabolism. Annual Review of Nutrition, 27, 19-40. (Pubitemid 351373346)
-
(2007)
Annual Review of Nutrition
, vol.27
, pp. 19-40
-
-
Mizushima, N.1
Klionsky, D.J.2
-
81
-
-
43049165453
-
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani, S. A., Guo, W., Liao, M. J., Eaton, E. N., Ayyanan, A., Zhou, A. Y., et al. (2008). The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell, 133, 704-715. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
82
-
-
84860578009
-
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumorinitiating cells
-
Celià-Terrassa, T., Meca-Cortés, O., Mateo, F., de Paz, A. M., Rubio, N., Arnal-Estapé, A., et al. (2012). Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumorinitiating cells. The Journal of Clinical Investigation, 122, 1849-1868.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, pp. 1849-1868
-
-
Celià-Terrassa, T.1
Meca-Cortés, O.2
Mateo, F.3
De Paz, A.M.4
Rubio, N.5
Arnal-Estapé, A.6
-
83
-
-
79954423356
-
Acidic stress promotes a glioma stem cell phenotype
-
Hjelmeland, A. B., Wu, Q., Heddleston, J. M., Choudhary, G. S., MacSwords, J., Lathia, J. D., et al. (2011). Acidic stress promotes a glioma stem cell phenotype. Cell Death and Differentiation, 18, 829-840.
-
(2011)
Cell Death and Differentiation
, vol.18
, pp. 829-840
-
-
Hjelmeland, A.B.1
Wu, Q.2
Heddleston, J.M.3
Choudhary, G.S.4
MacSwords, J.5
Lathia, J.D.6
-
84
-
-
84880120014
-
Cancer-generated lactic acid: A regulatory, immunosuppressive metabolite?
-
Choi, S. Y., Collins, C. C., Gout, P. W., & Wang, Y. (2013). Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite? The Journal of Pathology, 230(4), 350-355.
-
(2013)
The Journal of Pathology
, vol.230
, Issue.4
, pp. 350-355
-
-
Choi, S.Y.1
Collins, C.C.2
Gout, P.W.3
Wang, Y.4
-
85
-
-
0035071662
-
The effects of extracellular pH on immune function
-
Lardner, A. (2001). The effects of extracellular pH on immune function. Journal of Leukocyte Biology, 69, 522-530.
-
(2001)
Journal of Leukocyte Biology
, vol.69
, pp. 522-530
-
-
Lardner, A.1
-
86
-
-
33344467760
-
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression
-
DOI 10.1182/blood-2005-05-1795
-
Gottfried, E., Kunz-Schughart, L. A., Ebner, S., Mueller-Klieser, W., Hoves, S., Andreesen, R., et al. (2006). Tumor-derived lactic acid modulates dendritic cell activation and antigen expression. Blood, 107, 2013-2021. (Pubitemid 43289385)
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 2013-2021
-
-
Gottfried, E.1
Kunz-Schughart, L.A.2
Ebner, S.3
Mueller-Klieser, W.4
Hoves, S.5
Andreesen, R.6
Mackensen, A.7
Kreutz, M.8
-
87
-
-
84861861104
-
Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes
-
Calcinotto, A., Filipazzi, P., Grioni, M., Iero, M., De Milito, A., Ricupito, A., et al. (2012). Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes. Cancer Research, 72, 2746-2756.
-
(2012)
Cancer Research
, vol.72
, pp. 2746-2756
-
-
Calcinotto, A.1
Filipazzi, P.2
Grioni, M.3
Iero, M.4
De Milito, A.5
Ricupito, A.6
-
88
-
-
84861545489
-
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
-
Mendler, A. N., Hu, B., Prinz, P. U., Kreutz, M., Gottfried, E., & Noessner, E. (2012). Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation. International Journal of Cancer, 131, 633-640.
-
(2012)
International Journal of Cancer
, vol.131
, pp. 633-640
-
-
Mendler, A.N.1
Hu, B.2
Prinz, P.U.3
Kreutz, M.4
Gottfried, E.5
Noessner, E.6
-
89
-
-
84879203221
-
Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity
-
Ohashi, T., Akazawa, T., Aoki, M., Kuze, B., Mizuta, K., Ito, Y., et al. (2013). Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity. International Journal of Cancer, 133, 1107-1118.
-
(2013)
International Journal of Cancer
, vol.133
, pp. 1107-1118
-
-
Ohashi, T.1
Akazawa, T.2
Aoki, M.3
Kuze, B.4
Mizuta, K.5
Ito, Y.6
-
90
-
-
84857716739
-
Multiple biological activities of lactic acid in cancer: Influences on tumor growth, angiogenesis and metastasis
-
Dhup, S., Dadhich, R. K., Porporato, P. E., & Sonveaux, P. (2012). Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis. Current Pharmaceutical Design, 18, 1319 - 1330.
-
(2012)
Current Pharmaceutical Design
, vol.18
, pp. 1319-1330
-
-
Dhup, S.1
Dadhich, R.K.2
Porporato, P.E.3
Sonveaux, P.4
-
91
-
-
79960029992
-
Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release
-
Goetze, K., Walenta, S., Ksiazkiewicz, M., Kunz-Schughart, L. A., & Mueller-Klieser, W. (2011). Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release. International Journal of Oncology, 9, 453-463.
-
(2011)
International Journal of Oncology
, vol.9
, pp. 453-463
-
-
Goetze, K.1
Walenta, S.2
Ksiazkiewicz, M.3
Kunz-Schughart, L.A.4
Mueller-Klieser, W.5
-
92
-
-
33745519159
-
Lactate stimulates endothelial cell migration
-
DOI 10.1111/j.1743-6109.2006.00127.x
-
Beckert, S., Farrahi, F., Aslam, R. S., Scheuenstuhl, H., Königsrainer, A., Hussain, M. Z., et al. (2006). Lactate stimulates endothelial cell migration. Wound Repair and Regeneration, 14, 321-324. (Pubitemid 43979262)
-
(2006)
Wound Repair and Regeneration
, vol.14
, Issue.3
, pp. 321-324
-
-
Beckert, S.1
Farrahi, F.2
Aslam, R.S.3
Scheuenstuhl, H.4
Konigsrainer, A.5
Hussain, M.Z.6
Hunt, T.K.7
-
93
-
-
79953329777
-
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis
-
Végran, F., Boidot, R., Michiels, C., Sonveaux, P., & Feron, O. (2011). Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis. Cancer Research, 71(7), 2550-2560.
-
(2011)
Cancer Research
, vol.71
, Issue.7
, pp. 2550-2560
-
-
Végran, F.1
Boidot, R.2
Michiels, C.3
Sonveaux, P.4
Feron, O.5
-
94
-
-
58149157900
-
The genomic analysis of lactic acidosis and acidosis response in human cancers
-
Chen, J. L., Lucas, J. E., Schroeder, T., Mori, S., Wu, J., Nevins, J., et al. (2008). The genomic analysis of lactic acidosis and acidosis response in human cancers. PLoS Genetics, 4, e1000293.
-
(2008)
PLoS Genetics
, vol.4
-
-
Chen, J.L.1
Lucas, J.E.2
Schroeder, T.3
Mori, S.4
Wu, J.5
Nevins, J.6
-
95
-
-
33646428345
-
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs
-
Thews, O., Gassner, B., Kelleher, D. K., Schwerdt, G., & Gekle, M. (2006). Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia, 8, 14352.
-
(2006)
Neoplasia
, vol.8
, pp. 14352
-
-
Thews, O.1
Gassner, B.2
Kelleher, D.K.3
Schwerdt, G.4
Gekle, M.5
-
96
-
-
0034143570
-
pH and drug resistance in tumors
-
DOI 10.1054/drup.2000.0119
-
Raghunand, N., & Gillies, R. J. (2002). pH and drug resistance in tumors. Drug Resistance Updates, 3, 39-47. (Pubitemid 30246567)
-
(2000)
Drug Resistance Updates
, vol.3
, Issue.1
, pp. 39-47
-
-
Raghunand, N.1
Gillies, R.J.2
-
97
-
-
0026720341
-
Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours
-
Newell, K., Wood, P., Stratford, I., & Tannock, I. (1992). Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours. British Journal of Cancer, 66, 311-317.
-
(1992)
British Journal of Cancer
, vol.66
, pp. 311-317
-
-
Newell, K.1
Wood, P.2
Stratford, I.3
Tannock, I.4
-
98
-
-
0035312445
-
Acidic environment modifies heat- or radiation-induced apoptosis in human maxillary cancer cells
-
Ohtsubo, T., Igawa, H., Saito, T., Matsumoto, H., Park, H. J., Song, C. W., et al. (2001). Acidic environment modifies heat- or radiation-induced apoptosis in human maxillary cancer cells. International Journal of Radiation Oncology, Biology, and Physics, 49, 1391-8131.
-
(2001)
International Journal of Radiation Oncology, Biology, and Physics
, vol.49
, pp. 1391-8131
-
-
Ohtsubo, T.1
Igawa, H.2
Saito, T.3
Matsumoto, H.4
Park, H.J.5
Song, C.W.6
-
99
-
-
0001829242
-
The effect of environmental factors on the radiosensitivity of lymph nodes cultured in vitro
-
Trowell, O. A. (1953). The effect of environmental factors on the radiosensitivity of lymph nodes cultured in vitro. British Journal of Radiology, 306, 302-309.
-
(1953)
British Journal of Radiology
, vol.306
, pp. 302-309
-
-
Trowell, O.A.1
-
100
-
-
0018877325
-
The influence of pH on the survival after X-irradiation of cultured malignant cells. Effects of carbonylcyanide-3-chlorophenylhydrazone
-
Haveman, J. (1980). The influence of pH on the survival after X-irradiation of cultured malignant cells. Effects of carbonylcyanide-3- chlorophenylhydrazone. International Journal of Radiation Biology, 37, 201-205.
-
(1980)
International Journal of Radiation Biology
, vol.37
, pp. 201-205
-
-
Haveman, J.1
-
101
-
-
0030869505
-
p53-dependent induction of WAF1 by a low-ph culture condition in human glioblastoma cells
-
Ohtsubo, T., Wang, X., Takahashi, A., Ohnishi, K., Saito, H., Song, C. W., et al. (1997). p53-dependent induction of WAF1 by a low-pH culture condition in human glioblastoma cells. Cancer Research, 57(18), 3910-3913. (Pubitemid 27427674)
-
(1997)
Cancer Research
, vol.57
, Issue.18
, pp. 3910-3913
-
-
Ohtsubo, T.1
Wang, X.2
Takahashi, A.3
Ohnishi, K.4
Saito, H.5
Song, C.W.6
Ohnishi, T.7
-
102
-
-
0030742976
-
Radiation-induced apoptosis in different pH environments in vitro
-
DOI 10.1016/S0360-3016(97)00073-4, PII S0360301697000734
-
Lee, H. S., Park, H. J., Lyons, J. C., Griffin, R. J., Auger, E. A., & Song, C. W. (1997). Radiation-induced apoptosis in different pH environments in vitro. International Journal of Radiation Oncology, Biology, and Physics, 38(5), 1079-1087. (Pubitemid 27353689)
-
(1997)
International Journal of Radiation Oncology Biology Physics
, vol.38
, Issue.5
, pp. 1079-1087
-
-
Lee, H.-S.1
Park, H.J.2
Lyons, J.C.3
Griffin, R.J.4
Auger, E.A.5
Song, C.W.6
-
103
-
-
7444232599
-
Effect of pH on radiation-induced p53 expression
-
DOI 10.1016/j.ijrobp.2004.04.043, PII S0360301604006819
-
Choi, E. K., Roberts, K. P., Griffin, R. J., Han, T., Park, H. J., Song, C. W., et al. (2004). Effect of pH on radiation-induced p53 expression. International Journal of Radiation Oncology, Biology, and Physics, 60, 1264-1271. (Pubitemid 39440813)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.60
, Issue.4
, pp. 1264-1271
-
-
Choi, E.K.1
Roberts, K.P.2
Griffin, R.J.3
Han, T.4
Park, H.-J.5
Song, C.W.6
Park, H.J.7
-
104
-
-
0037230108
-
2-phase arrest caused by ionizing radiation
-
DOI 10.1667/0033-7587(2003)159[0086:IOEPOG]2.0.CO;2
-
Park, H. J., Lee, S. H., Chung, H., Rhee, Y. H., Lim, B. U., Ha, S. W., et al. (2003). Influence of environmental pH on G2-phase arrest caused by ionizing radiation. Radiation Research, 159, 86-93. (Pubitemid 36078158)
-
(2003)
Radiation Research
, vol.159
, Issue.1
, pp. 86-93
-
-
Park, H.J.1
Lee, S.H.2
Chung, H.3
Rhee, Y.H.4
Lim, B.U.5
Ha, S.W.6
Griffin, R.J.7
Lee, H.S.8
Song, C.W.9
Choi, E.K.10
-
105
-
-
77956212249
-
Tumor pH and its measurement
-
Zhang, X., Lin, Y., & Gillies, R. J. (2010). Tumor pH and its measurement. Journal of Nuclear Medicine, 51(8), 1167-1170.
-
(2010)
Journal of Nuclear Medicine
, vol.51
, Issue.8
, pp. 1167-1170
-
-
Zhang, X.1
Lin, Y.2
Gillies, R.J.3
-
106
-
-
33745575054
-
18F-FDG PET/CT 1.0
-
Delbeke, D., Coleman, R. E., Guiberteau, M. J., Brown, M. L., Royal, H. D., Siegel, B. A., et al. (2006). Procedure guideline for tumor imaging with 18F-FDG PET/CT 1.0. Journal of Nuclear Medicine, 47(5), 885-895. (Pubitemid 46768453)
-
(2006)
Journal of Nuclear Medicine
, vol.47
, Issue.5
, pp. 885-895
-
-
Delbeke, D.1
Coleman, R.E.2
Guiberteau, M.J.3
Brown, M.L.4
Royal, H.D.5
Siegel, B.A.6
Townsend, D.W.7
Berland, L.L.8
Parker, J.A.9
Hubner, K.10
Stabin, M.G.11
Zubal, G.12
Kachelriess, M.13
Cronin, V.14
Holbrook, S.15
-
107
-
-
33646272211
-
Translocation of a molecules into cells by pH-dependent insertion of a transmembrane helix
-
Reshetnyak, Y. K., Andreev, O. A., Lehnert, U., & Engelman, D. M. (2006). Translocation of a molecules into cells by pH-dependent insertion of a transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America, 103, 6460-6465.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 6460-6465
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Lehnert, U.3
Engelman, D.M.4
-
108
-
-
34848885103
-
A monomeric membrane peptide that lives in three worlds: In solution, attached to, and inserted across lipid bilayers
-
DOI 10.1529/biophysj.107.109967
-
Reshetnyak, Y. K., Segala, M., Andreev, O. A., & Engelman, D. M. (2007). A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers. Biophysical Journal, 93, 2363-2372. (Pubitemid 47511136)
-
(2007)
Biophysical Journal
, vol.93
, Issue.7
, pp. 2363-2372
-
-
Reshetnyak, Y.K.1
Segala, M.2
Andreev, O.A.3
Engelman, D.M.4
-
109
-
-
34249949775
-
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo
-
DOI 10.1073/pnas.0702439104
-
Andreev, O. A., Dupuy, A. D., Segala, M., Sandugu, S., Serra, D. A., Chichester, C. O., et al. (2007). Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo. Proceedings of the National Academy of Sciences of the United States of America, 104, 7893-7898. (Pubitemid 47185847)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.19
, pp. 7893-7898
-
-
Andreev, O.A.1
Dupuy, A.D.2
Segala, M.3
Sandugu, S.4
Serra, D.A.5
Chichester, C.O.6
Engelman, D.M.7
Reshetnyak, Y.K.8
-
110
-
-
66249099231
-
A novel technology for the imaging of acidic prostate tumors by positron emission tomography
-
Vāvere, A. L., Biddlecombe, G. B., Spees, W. M., Garbow, J. R., Wijesinghe, D., Andreev, O. A., et al. (2009). A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer Research, 69(10), 4510-4516.
-
(2009)
Cancer Research
, vol.69
, Issue.10
, pp. 4510-4516
-
-
Vavere, A.L.1
Biddlecombe, G.B.2
Spees, W.M.3
Garbow, J.R.4
Wijesinghe, D.5
Andreev, O.A.6
-
111
-
-
0033592178
-
A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications
-
Aime, S., Botta, M., Crich, S. G., Giovenzana, G., Palmisano, G., & Sisti, M. (1999). A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications. Chemical communications (Cambridge), 16, 1577-1578. (Pubitemid 29391229)
-
(1999)
Chemical Communications
, Issue.16
, pp. 1577-1578
-
-
Aime, S.1
Botta, M.2
Crich, S.G.3
Giovenzana, G.4
Palmisano, G.5
Sisti, M.6
-
112
-
-
0033517750
-
A novel pH-sensitive MRI contrast agent
-
DOI 10.1002/(SICI)1521-3773(19991102)38:21<3192::AI
-
Zhang, S., Wu, K., & Sherry, A. D. (1999). A novel pH-sensitive MRI contrast agent. Angewandte Chemie International Edition in English, 38, 3192-3194. (Pubitemid 29533893)
-
(1999)
Angewandte Chemie - International Edition
, vol.38
, Issue.21
, pp. 3192-3194
-
-
Zhang, S.1
Wu, K.2
Dean, S.A.3
-
113
-
-
32544443295
-
e imaging of rat glioma using pH-dependent relaxivity
-
DOI 10.1002/mrm.20773
-
Garcia-Martin, M. L., Martinez, G. V., Raghunand, N., Sherry, A. D., Zhang, S. R., & Gillies, R. J. (2006). High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity. Magnetic Resonance in Medicine, 55, 309-315. (Pubitemid 43238099)
-
(2006)
Magnetic Resonance in Medicine
, vol.55
, Issue.2
, pp. 309-315
-
-
Garcia-Martin, M.L.1
Martinez, G.V.2
Raghunand, N.3
Sherry, A.D.4
Zhang, S.5
Gillies, R.J.6
-
114
-
-
65549166946
-
Bicarbonate increases tumor pH and inhibits spontaneous metastases
-
Robey, I. F., Baggett, B. K., Kirkpatrick, N. D., Roe, D. J., Dosescu, J., Sloane, B. F., et al. (2009). Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Research, 69, 2260-2268.
-
(2009)
Cancer Research
, vol.69
, pp. 2260-2268
-
-
Robey, I.F.1
Baggett, B.K.2
Kirkpatrick, N.D.3
Roe, D.J.4
Dosescu, J.5
Sloane, B.F.6
-
115
-
-
65549170684
-
The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion
-
Silva, A. S., Yunes, J. A., Gillies, R. J., & Gatenby, R. A. (2009). The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion. Cancer Research, 69, 2677-2684.
-
(2009)
Cancer Research
, vol.69
, pp. 2677-2684
-
-
Silva, A.S.1
Yunes, J.A.2
Gillies, R.J.3
Gatenby, R.A.4
-
116
-
-
82355173293
-
Reduction of metastasis using a non-volatile buffer
-
Ibrahim Hashim, A., Cornnell, H. H., Coelho Ribeiro Mde, L., Abrahams, D., Cunningham, J., Lloyd, M., et al. (2011). Reduction of metastasis using a non-volatile buffer. Clinical and Experimental Metastasis, 28, 841-849.
-
(2011)
Clinical and Experimental Metastasis
, vol.28
, pp. 841-849
-
-
Ibrahim Hashim, A.1
Cornnell, H.H.2
Coelho Ribeiro Mde, L.3
Abrahams, D.4
Cunningham, J.5
Lloyd, M.6
-
117
-
-
36349001899
-
+-ATPases as a new strategy against cancer
-
DOI 10.1158/0008-5472.CAN-07-1805
-
Fais, S., De Milito, A., You, H., & Qin, W. (2007). Targeting vacuolar H+-ATPases as a new strategy against cancer. Cancer Research, 67, 10627-10630. (Pubitemid 350145883)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 10627-10630
-
-
Fais, S.1
De Milito, A.2
You, H.3
Qin, W.4
-
118
-
-
77953463274
-
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
-
De Milito, A., Canese, R., Marino, M. L., Borghi, M., Iero, M., Villa, A., et al. (2010). pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity. International Journal of Cancer, 127, 207-219.
-
(2010)
International Journal of Cancer
, vol.127
, pp. 207-219
-
-
De Milito, A.1
Canese, R.2
Marino, M.L.3
Borghi, M.4
Iero, M.5
Villa, A.6
-
119
-
-
36948999655
-
Erratum (Retracted Article): Blockage of intracellular proton extrusion with proton pump inhibitor induces apoptosis in gastric cancer (Cancer Science)
-
DOI 10.1111/j.1349-7006.2007.00642.x
-
Yeo, M., Kim, D. K., Park, H. J., Cho, S. W., Cheong, J. Y., & Lee, K. J. (2008). Retraction: blockage of intracellular proton extrusion with proton pump inhibitor induces apoptosis in gastric cancer. Cancer Science, 99, 185. (Pubitemid 350239049)
-
(2008)
Cancer Science
, vol.99
, Issue.1
, pp. 185
-
-
Yeo, M.1
Kim, D.-K.2
Park, H.-J.3
Cho, S.-W.4
Cheong, J.Y.5
Lee, K.J.6
-
120
-
-
69149104880
-
Biological effects of a new vacuolar-H,- ATPase inhibitor in colon carcinoma cell lines
-
Supino, R., Scovassi, A. I., Croce, A. C., Dal Bo, L., Favini, E., Corbelli, A., et al. (2009). Biological effects of a new vacuolar-H,- ATPase inhibitor in colon carcinoma cell lines. Annals of the New York Academy of Sciences, 1171, 606-616.
-
(2009)
Annals of the New York Academy of Sciences
, vol.1171
, pp. 606-616
-
-
Supino, R.1
Scovassi, A.I.2
Croce, A.C.3
Dal Bo, L.4
Favini, E.5
Corbelli, A.6
-
121
-
-
84856612269
-
The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
-
Lauritzen, G., Stock, C. M., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., et al. (2012). The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2. Cancer Letters, 317, 172-183.
-
(2012)
Cancer Letters
, vol.317
, pp. 172-183
-
-
Lauritzen, G.1
Stock, C.M.2
Lemaire, J.3
Lund, S.F.4
Jensen, M.F.5
Damsgaard, B.6
-
122
-
-
33846708762
-
+ exchanger
-
DOI 10.1016/j.leukres.2006.06.015, PII S014521260600230X
-
He, B., Deng, C., Zhang, M., Zou, D., & Xu, M. (2007). Reduction of intracellular pH inhibits the expression of VEGF in K562 cells after targeted inhibition of the Na+/H+ exchanger. Leukemia Research, 2007(31), 507-514. (Pubitemid 46198933)
-
(2007)
Leukemia Research
, vol.31
, Issue.4
, pp. 507-514
-
-
He, B.1
Deng, C.2
Zhang, M.3
Zou, D.4
Xu, M.5
-
123
-
-
84870013632
-
Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity
-
Provost, J. J., Rastedt, D., Canine, J., Ngyuen, T., Haak, A., Kutz, C., et al. (2012). Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity. Cellular Oncology, 2012(35), 95-110.
-
(2012)
Cellular Oncology
, vol.2012
, Issue.35
, pp. 95-110
-
-
Provost, J.J.1
Rastedt, D.2
Canine, J.3
Ngyuen, T.4
Haak, A.5
Kutz, C.6
-
124
-
-
84878396462
-
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
-
Commisso, C., Davidson, S. M., Soydaner-Azeloglu, R. G., Parker, S. J., Kamphorst, J. J., Hackett, S., et al. (2013). Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature, 497, 633-637.
-
(2013)
Nature
, vol.497
, pp. 633-637
-
-
Commisso, C.1
Davidson, S.M.2
Soydaner-Azeloglu, R.G.3
Parker, S.J.4
Kamphorst, J.J.5
Hackett, S.6
-
125
-
-
0037100861
-
Cytostatic potential of novel agents that inhibit the regulation of intracellular pH
-
Wong, P., Kleemann, H. W., & Tannock, I. F. (2002). Cytostatic potential of novel agents that inhibit the regulation of intracellular pH. British Journal of Cancer, 87(2), 238-245.
-
(2002)
British Journal of Cancer
, vol.87
, Issue.2
, pp. 238-245
-
-
Wong, P.1
Kleemann, H.W.2
Tannock, I.F.3
-
126
-
-
84887070095
-
Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs - An integral molecular/biochemical/metabolic/ clinical approach after one hundred years of cancer research
-
Harguindey, S., Arranz, J. L., Polo Orozco, J. D., Rauch, C., Fais, S., Cardone, R. A., et al. (2013). Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs - an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research. Journal of Translational Medicine, 11(1), 282.
-
(2013)
Journal of Translational Medicine
, vol.11
, Issue.1
, pp. 282
-
-
Harguindey, S.1
Arranz, J.L.2
Polo Orozco, J.D.3
Rauch, C.4
Fais, S.5
Cardone, R.A.6
-
127
-
-
80053932947
-
Inhibition of K562 leukemia angiogenesis and growth by selective Na+/H+ exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF
-
Gao, W., Chang, G., Wang, J., Jin, W., Wang, L., Lin, Y., et al. (2011). Inhibition of K562 leukemia angiogenesis and growth by selective Na+/H+ exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF. Leukemia Research, 11, 1506-1511.
-
(2011)
Leukemia Research
, vol.11
, pp. 1506-1511
-
-
Gao, W.1
Chang, G.2
Wang, J.3
Jin, W.4
Wang, L.5
Lin, Y.6
-
128
-
-
4544279148
-
+-ATPase in cancer biology
-
DOI 10.1385/CBB:40:2:185
-
Sennoune, S. R., Luo, D., & Martínez-Zaguilán, R. (2004). Plasmalemmal vacuolar-type H+-ATPase in cancer biology. Cell Biochemistry and Biophysics, 40(2), 185-206. (Pubitemid 41270787)
-
(2004)
Cell Biochemistry and Biophysics
, vol.40
, Issue.2
, pp. 185-206
-
-
Sennoune, S.R.1
Luo, D.2
Martinez-Zaguilan, R.3
-
129
-
-
9744260934
-
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs
-
DOI 10.1093/jnci/djh305
-
Luciani, F., Spada, M., De Milito, A., Molinari, A., Rivoltini, L., Montinaro, A., et al. (2004). Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. Journal of the National Cancer Institute, 96, 1702-1713. (Pubitemid 39585639)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.22
, pp. 1702-1713
-
-
Luciani, F.1
Spada, M.2
De Milito, A.3
Molinari, A.4
Rivoltini, L.5
Montinaro, A.6
Marra, M.7
Lugini, L.8
Logozzi, M.9
Lozupone, F.10
Federici, C.11
Iessi, E.12
Parmiani, G.13
Arancia, G.14
Belardelli, F.15
Fais, S.16
-
130
-
-
84863822889
-
Effects of pantoprazole as a HIF-1α inhibitor on human gastric adenocarcinoma sgc-7901 cells
-
Shen, Y., Wu, Y., Chen, M., Shen, W., Huang, S., Zhang, L., et al. (2012). Effects of pantoprazole as a HIF-1α inhibitor on human gastric adenocarcinoma sgc-7901 cells. Neoplasma, 59, 142-149.
-
(2012)
Neoplasma
, vol.59
, pp. 142-149
-
-
Shen, Y.1
Wu, Y.2
Chen, M.3
Shen, W.4
Huang, S.5
Zhang, L.6
-
131
-
-
0036594889
-
Regulation of intracellular pH in human melanoma: Potential therapeutic implications
-
Wahl, M. L., Owen, J. A., Burd, R., Herlands, R. A., Nogami, S. S., Rodeck, U., et al. (2002). Regulation of intracellular pH in human melanoma: potential therapeutic implications. Molecular Cancer Therapeutics, 1(8), 617-628.
-
(2002)
Molecular Cancer Therapeutics
, vol.1
, Issue.8
, pp. 617-628
-
-
Wahl, M.L.1
Owen, J.A.2
Burd, R.3
Herlands, R.A.4
Nogami, S.S.5
Rodeck, U.6
-
132
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran, C. T. (2008). Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nature Reviews Drug Discovery, 7, 168-181.
-
(2008)
Nature Reviews Drug Discovery
, vol.7
, pp. 168-181
-
-
Supuran, C.T.1
|