Inhibition of K562 leukemia angiogenesis and growth by selective Na +/H + exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF

Leukemia Research

Volumn 35, Issue 11, 2011, Pages 1506-1511

  Gao, Wei ^a   Chang, Guoqiang ^a   Wang, Jian ^a   Jin, Weina ^a   Wang, Lihong ^a   Lin, Yani ^a   Li, Huawen ^a   Ma, Li ^a   Li, Qinghua ^a   Pang, Tianxiang ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

Author keywords

Angiogenesis; Intracellular pH (pHi); K562 cells; Leukemia; Na + H + exchanger isoform1 (NHE1); Vascular endothelial growth factor (VEGF)

Indexed keywords

CARIPORIDE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MICROVASCULATURE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN SECRETION; TUMOR VASCULARIZATION; UMBILICAL VEIN;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GUANIDINES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LEUKEMIA; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; SODIUM-HYDROGEN ANTIPORTER; SULFONES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80053932947     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.07.001     Document Type: Article

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