Extracellular acidity as favouring factor of tumor progression and metastatic dissemination

Experimental Oncology

Volumn 34, Issue 2, 2012, Pages 79-84

  Calorini, L ^a   Peppicelli, S ^a   Bianchini, F ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Extracellular acidity; Invasiveness, metastatic dissemination; Proton pump inhibitors

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOSTATIN; ANTINEOPLASTIC AGENT; BICARBONATE; CARBONATE DEHYDRATASE INHIBITOR; CATHEPSIN D; CATHEPSIN L; COLLAGEN; DOXORUBICIN; ENDOSTATIN; ESOMEPRAZOLE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MATRIX METALLOPROTEINASE; MITOXANTRONE; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER INHIBITOR; OMEPRAZOLE; OXYGEN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROTON PUMP INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR; VASCULOTROPIN A;

ACIDITY; ACIDOSIS; ANAEROBIC METABOLISM; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; BREAST CARCINOMA; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER RADIOTHERAPY; CANCER RESISTANCE; CELL LINEAGE; CELL MOTILITY; CELL PH; CELL PROLIFERATION; CELL SURVIVAL; COLITIS; COLON CARCINOGENESIS; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CYTOTOXICITY; DRUG SAFETY; EXTRACELLULAR MATRIX; EXTRACELLULAR SPACE; GENOMIC INSTABILITY; GLYCOLYSIS; HUMAN; HYPOXIA; INFLAMMATORY CELL; KIDNEY TUBULE ACIDOSIS; LIVER CARCINOMA; LYMPHOMA CELL; MACROPHAGE; MELANOMA; METABOLIC ALKALOSIS; METASTASIS; METASTASIS INHIBITION; METASTASIS POTENTIAL; MONOCYTE; MYOFIBROBLAST; NONHUMAN; OXYGEN TENSION; PANCREAS CARCINOMA; PROTEIN DEGRADATION; PROTON TRANSPORT; RADIOSENSITIVITY; REVIEW; SENSITIVITY AND SPECIFICITY; SICKLE CELL ANEMIA; TISSUE PERFUSION; TISSUE PRESSURE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR BLOOD FLOW; TUMOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION; ZOLLINGER ELLISON SYNDROME;

ACID-BASE EQUILIBRIUM; ANIMALS; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; EXTRACELLULAR FLUID; HUMANS; HYDROGEN-ION CONCENTRATION; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; PROTON PUMP INHIBITORS;

EID: 84865963556     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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