The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion

Cancer Research

Volumn 69, Issue 6, 2009, Pages 2677-2684

  Silva, Ariosto S ^a   Yunes, Jose A ^a   Gillies, Robert J ^b   Gatenby, Robert A ^b  

^a CENTRO INFANTIL BOLDRINI   (Brazil)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BUFFER; CARBON DIOXIDE; GLUCOSE; OXYGEN;

ACIDITY; ACIDOSIS; ARTICLE; BLOOD PH; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CELL INVASION; CELL PH; COMPETITIVE INHIBITION; COMPUTER MODEL; COMPUTER SIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXTRACELLULAR SPACE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR; TUMOR CELL; TUMOR GROWTH; BIOLOGICAL MODEL; BLOOD; EXTRACELLULAR FLUID; KINETICS; METABOLISM; MULTICELLULAR SPHEROID; NEOPLASM; PATHOLOGY; PH; PRESSURE; VASCULARIZATION;

BUFFERS; CARBON DIOXIDE; COMPUTER SIMULATION; EXTRACELLULAR FLUID; GLUCOSE; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, BIOLOGICAL; NEOPLASMS; OXYGEN; PARTIAL PRESSURE; SODIUM BICARBONATE; SPHEROIDS, CELLULAR;

EID: 65549170684     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-2394     Document Type: Article

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