-
1
-
-
46049109335
-
Tumor lymphangiogenesis and melanoma metastasis
-
18481261 10.1002/jcp.21494 1:CAS:528:DC%2BD1cXotFyrt7w%3D
-
Rinderknecht M, Detmar M (2008) Tumor lymphangiogenesis and melanoma metastasis. J Cell Physiol 216:347-354
-
(2008)
J Cell Physiol
, vol.216
, pp. 347-354
-
-
Rinderknecht, M.1
Detmar, M.2
-
2
-
-
0038243830
-
Tumor lymphangiogenesis: A novel prognostic indicator for cutaneous melanoma metastasis and survival
-
12759251 10.1016/S0002-9440(10)64328-3
-
Dadras SS, Paul T, Bertoncini J, Brown LF, Muzikansky A, Jackson DG et al (2003) Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival. Am J Pathol 162:1951-1960
-
(2003)
Am J Pathol
, vol.162
, pp. 1951-1960
-
-
Dadras, S.S.1
Paul, T.2
Bertoncini, J.3
Brown, L.F.4
Muzikansky, A.5
Jackson, D.G.6
-
3
-
-
25444525461
-
Opinion: Emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis
-
16079909 10.1038/nrc1693 1:CAS:528:DC%2BD2MXpsleksL8%3D
-
Cao Y (2005) Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis. Nat Rev Cancer 5:735-743
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 735-743
-
-
Cao, Y.1
-
4
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
20178740 10.1016/j.cell.2010.01.045 1:CAS:528:DC%2BC3cXlt1KltrY%3D
-
Tammela T, Alitalo K (2010) Lymphangiogenesis: molecular mechanisms and future promise. Cell 140:460-476
-
(2010)
Cell
, vol.140
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
5
-
-
30744477450
-
Lymphangiogenesis in development and human disease
-
16355212 10.1038/nature04480 1:CAS:528:DC%2BD2MXhtlSksrnN
-
Alitalo K, Tammela T, Petrova TV (2005) Lymphangiogenesis in development and human disease. Nature 438:946-953
-
(2005)
Nature
, vol.438
, pp. 946-953
-
-
Alitalo, K.1
Tammela, T.2
Petrova, T.V.3
-
6
-
-
0035129906
-
From angiogenesis to lymphangiogenesis
-
11175837 10.1038/84579 1:CAS:528:DC%2BD3MXhtVyht74%3D
-
Plate K (2001) From angiogenesis to lymphangiogenesis. Nat Med 7:151-152
-
(2001)
Nat Med
, vol.7
, pp. 151-152
-
-
Plate, K.1
-
7
-
-
13844265843
-
Focus on lymphangiogenesis in tumor metastasis
-
15710325 10.1016/j.ccr.2005.01.017 1:CAS:528:DC%2BD2MXitFygu70%3D
-
Achen MG, McColl BK, Stacker SA (2005) Focus on lymphangiogenesis in tumor metastasis. Cancer Cell 7:121-127
-
(2005)
Cancer Cell
, vol.7
, pp. 121-127
-
-
Achen, M.G.1
McColl, B.K.2
Stacker, S.A.3
-
8
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
14634646 10.1038/ni1013 1:CAS:528:DC%2BD3sXhtVWhtrzO
-
Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV et al (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5:74-80
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
-
9
-
-
33847198622
-
The role of the VEGF-C/VEGFR-3 axis in cancer progression
-
17164762 10.1038/sj.bjc.6603487 1:CAS:528:DC%2BD2sXhvV2jsbg%3D
-
Su JL, Yen CJ, Chen PS, Chuang SE, Hong CC, Kuo IH et al (2007) The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer 96:541-545
-
(2007)
Br J Cancer
, vol.96
, pp. 541-545
-
-
Su, J.L.1
Yen, C.J.2
Chen, P.S.3
Chuang, S.E.4
Hong, C.C.5
Kuo, I.H.6
-
10
-
-
54249140119
-
Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axis
-
18829538 10.1158/0008-5472.CAN-08-1488 1:CAS:528:DC%2BD1cXhtF2msLzI
-
Burton JB, Priceman SJ, Sung JL, Brakenhielm E, An DS, Pytowski B et al (2008) Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axis. Cancer Res 68:7828-7837
-
(2008)
Cancer Res
, vol.68
, pp. 7828-7837
-
-
Burton, J.B.1
Priceman, S.J.2
Sung, J.L.3
Brakenhielm, E.4
An, D.S.5
Pytowski, B.6
-
11
-
-
21144437844
-
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
-
15930292 10.1158/0008-5472.CAN-04-4576 1:CAS:528:DC%2BD2MXks1OhtbY%3D
-
He Y, Rajantie I, Pajusola K, Jeltsch M, Holopainen T, Yla-Herttuala S et al (2005) Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res 65:4739-4746
-
(2005)
Cancer Res
, vol.65
, pp. 4739-4746
-
-
He, Y.1
Rajantie, I.2
Pajusola, K.3
Jeltsch, M.4
Holopainen, T.5
Yla-Herttuala, S.6
-
12
-
-
0037024472
-
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
-
12048269 10.1093/jnci/94.11.819 1:CAS:528:DC%2BD38Xlt1Sqs7w%3D
-
He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T et al (2002) Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst 94:819-825
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 819-825
-
-
He, Y.1
Kozaki, K.2
Karpanen, T.3
Koshikawa, K.4
Yla-Herttuala, S.5
Takahashi, T.6
-
13
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
11175850 10.1038/84643 1:CAS:528:DC%2BD3MXhtVylu7s%3D
-
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P et al (2001) Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 7:192-198
-
(2001)
Nat Med
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
Prevo, R.4
Janes, L.5
Velasco, P.6
-
14
-
-
33947494918
-
Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis
-
17255343 10.2353/ajpath.2007.060761
-
Harrell MI, Iritani BM, Ruddell A (2007) Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am J Pathol 170:774-786
-
(2007)
Am J Pathol
, vol.170
, pp. 774-786
-
-
Harrell, M.I.1
Iritani, B.M.2
Ruddell, A.3
-
15
-
-
33748075460
-
Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: Therapeutic implications
-
16912183 10.1158/0008-5472.CAN-06-1392 1:CAS:528:DC%2BD28XotFWqtL8%3D
-
Hoshida T, Isaka N, Hagendoorn J, di Tomaso E, Chen YL, Pytowski B, Fukumura D, Padera TP, Jain RK (2006) Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res 66:8065-8075
-
(2006)
Cancer Res
, vol.66
, pp. 8065-8075
-
-
Hoshida, T.1
Isaka, N.2
Hagendoorn, J.3
Di Tomaso, E.4
Chen, Y.L.5
Pytowski, B.6
Fukumura, D.7
Padera, T.P.8
Jain, R.K.9
-
16
-
-
33846180704
-
Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics
-
17160713 10.1007/s10555-006-9026-y
-
Ji RC (2006) Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: new insights into intratumoral and peritumoral lymphatics. Cancer Metastasis Rev 25:677-694
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 677-694
-
-
Ji, R.C.1
-
17
-
-
0037441913
-
Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma
-
12569601 10.1002/cncr.11159 1:CAS:528:DC%2BD3sXhsFOnsbs%3D
-
Kunkel M, Reichert TE, Benz P, Lehr HA, Jeong JH, Wieand S, Bartenstein P, Wagner W, Whiteside TL (2003) Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma. Cancer 97:1015-1024
-
(2003)
Cancer
, vol.97
, pp. 1015-1024
-
-
Kunkel, M.1
Reichert, T.E.2
Benz, P.3
Lehr, H.A.4
Jeong, J.H.5
Wieand, S.6
Bartenstein, P.7
Wagner, W.8
Whiteside, T.L.9
-
18
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
9018236 10.1038/nm0297-177 1:CAS:528:DyaK2sXpsVOktw%3D%3D
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med 3:177-182
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
19
-
-
0037348402
-
Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors
-
12659686 1:CAS:528:DC%2BD3sXjt1ykt7w%3D
-
Schornack PA, Gillies RJ (2003) Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors. Neoplasia 5:135-145
-
(2003)
Neoplasia
, vol.5
, pp. 135-145
-
-
Schornack, P.A.1
Gillies, R.J.2
-
22
-
-
62149142874
-
V-ATPase functions in normal and disease processes
-
18026982 10.1007/s00424-007-0382-4 1:CAS:528:DC%2BD1MXjvFOhtg%3D%3D
-
Hinton A, Bond S, Forgac M (2009) V-ATPase functions in normal and disease processes. Pflugers Arch 457:589-598
-
(2009)
Pflugers Arch
, vol.457
, pp. 589-598
-
-
Hinton, A.1
Bond, S.2
Forgac, M.3
-
23
-
-
72949121897
-
Sensors and regulators of intracellular pH
-
19997129 10.1038/nrm2820 1:CAS:528:DC%2BD1MXhsFaqtL3K
-
Casey JR, Grinstein S, Orlowski J (2010) Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol 11:50-61
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 50-61
-
-
Casey, J.R.1
Grinstein, S.2
Orlowski, J.3
-
24
-
-
0034652620
-
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
-
10706105 1:CAS:528:DC%2BD3cXhs1Shsrk%3D
-
Walenta S, Wetterling M, Lehrke M, Schwickert G, Sundfør K, Rofstad EK, Mueller-Klieser W (2000) High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res 60:916-921
-
(2000)
Cancer Res
, vol.60
, pp. 916-921
-
-
Walenta, S.1
Wetterling, M.2
Lehrke, M.3
Schwickert, G.4
Sundfør, K.5
Rofstad, E.K.6
Mueller-Klieser, W.7
-
25
-
-
0034884690
-
Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone
-
11494116 10.1038/sj.neo.7900151 1:CAS:528:DC%2BD3MXmsVynu7c%3D
-
Raghunand N, Mahoney B, van Sluis R, Baggett B, Gillies RJ (2001) Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia 3:227-235
-
(2001)
Neoplasia
, vol.3
, pp. 227-235
-
-
Raghunand, N.1
Mahoney, B.2
Van Sluis, R.3
Baggett, B.4
Gillies, R.J.5
-
26
-
-
34247352844
-
Inhibitory effect of tumor cell-derived lactic acid on human T cells
-
17255361 10.1182/blood-2006-07-035972 1:CAS:528:DC%2BD2sXkvFCitLs%3D
-
Fischer K, Hoffmann P, Voelkl S, Meidenbauer N, Ammer J, Edinger M et al (2007) Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood 109:3812-3819
-
(2007)
Blood
, vol.109
, pp. 3812-3819
-
-
Fischer, K.1
Hoffmann, P.2
Voelkl, S.3
Meidenbauer, N.4
Ammer, J.5
Edinger, M.6
-
27
-
-
0026623304
-
Clastogenicity of low pH to various cultured mammalian cells
-
1379335 10.1016/0027-5107(92)90235-T 1:STN:280:DyaK38zltVWrsQ%3D%3D
-
Morita T, Nagaki T, Fukuda I, Okumura K (1992) Clastogenicity of low pH to various cultured mammalian cells. Mutat Res 268:297-305
-
(1992)
Mutat Res
, vol.268
, pp. 297-305
-
-
Morita, T.1
Nagaki, T.2
Fukuda, I.3
Okumura, K.4
-
28
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
16818644 10.1158/0008-5472.CAN-06-0983 1:CAS:528:DC%2BD28XmsVamu74%3D
-
Rofstad EK, Mathiesen B, Kindem K, Galappathi K (2006) Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 66:6699-6707
-
(2006)
Cancer Res
, vol.66
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
29
-
-
44449089860
-
Acid treatment of melanoma cells selects for invasive phenotypes
-
18301995 10.1007/s10585-008-9145-7 1:CAS:528:DC%2BD1cXptVWjs74%3D
-
Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ (2008) Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis 25:411-425
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 411-425
-
-
Moellering, R.E.1
Black, K.C.2
Krishnamurty, C.3
Baggett, B.K.4
Stafford, P.5
Rain, M.6
Gatenby, R.A.7
Gillies, R.J.8
-
30
-
-
34548038993
-
Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis
-
17699768 10.1158/0008-5472.CAN-06-3459 1:CAS:528:DC%2BD2sXptVGlsLs%3D
-
Provent P, Benito M, Hiba B, Farion R, López-Larrubia P, Ballesteros P, Rémy C, Segebarth C, Cerdán S, Coles JA, García-Martín ML (2007) Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis. Cancer Res 67:7638-7645
-
(2007)
Cancer Res
, vol.67
, pp. 7638-7645
-
-
Provent, P.1
Benito, M.2
Hiba, B.3
Farion, R.4
López-Larrubia, P.5
Ballesteros, P.6
Rémy, C.7
Segebarth, C.8
Cerdán, S.9
Coles, J.A.10
García-Martín, M.L.11
-
31
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
16724055 10.1038/nature04871
-
Pouysségur J, Dayan F, Mazure NM (2006) Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441:437-443
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouysségur, J.1
Dayan, F.2
Mazure, N.M.3
-
32
-
-
0035927544
-
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells
-
11439338 10.1038/sj.onc.1204500 1:CAS:528:DC%2BD3MXltVKnsbw%3D
-
Shi Q, Le X, Wang B, Abbruzzese JL, Xiong Q, He Y et al (2001) Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. Oncogene 20:3751-3756
-
(2001)
Oncogene
, vol.20
, pp. 3751-3756
-
-
Shi, Q.1
Le, X.2
Wang, B.3
Abbruzzese, J.L.4
Xiong, Q.5
He, Y.6
-
33
-
-
0032473399
-
Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines
-
9495238 10.1002/(SICI)1097-0215(19980302)75:5<706: AID-IJC8>3.0.CO;2-2 1:CAS:528:DyaK1cXhsVyhtLc%3D
-
Scott PA, Gleadle JM, Bicknell R, Harris AL (1998) Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines. Int J Cancer 75:706-712
-
(1998)
Int J Cancer
, vol.75
, pp. 706-712
-
-
Scott, P.A.1
Gleadle, J.M.2
Bicknell, R.3
Harris, A.L.4
-
34
-
-
58649107348
-
Microenvironment changes (in pH) affect VEGF alternative splicing
-
19308691 10.1007/s12307-008-0013-4
-
Elias AP, Dias S (2008) Microenvironment changes (in pH) affect VEGF alternative splicing. Cancer Microenviron 1:131-139
-
(2008)
Cancer Microenviron
, vol.1
, pp. 131-139
-
-
Elias, A.P.1
Dias, S.2
-
35
-
-
84865316843
-
Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells
-
22730244 10.1002/stem.1160 1:CAS:528:DC%2BC38XhsVKlurjF
-
Santini R, Vinci MC, Pandolfi S, Penachioni JY, Montagnani V, Olivito B et al (2012) Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells. Stem Cells 30:1808-1818
-
(2012)
Stem Cells
, vol.30
, pp. 1808-1818
-
-
Santini, R.1
Vinci, M.C.2
Pandolfi, S.3
Penachioni, J.Y.4
Montagnani, V.5
Olivito, B.6
-
36
-
-
0017346890
-
In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain
-
65285 10.1016/0014-4827(77)90089-1 1:STN:280:DyaE2s7hsF2ltg%3D%3D
-
Chen TR (1977) In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. Exp Cell Res 104:255-262
-
(1977)
Exp Cell Res
, vol.104
, pp. 255-262
-
-
Chen, T.R.1
-
37
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] Method
-
11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] Method. Methods 25(4):402-408
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
38
-
-
0030026897
-
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
Apr 1 PubMed PMID: 8612600; PubMed Central PMCID: PMC450088
-
Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, Saksela O,Kalkkinen N, Alitalo K. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 1996 Apr 1;15(7):1751. PubMed PMID: 8612600; PubMed Central PMCID: PMC450088
-
(1996)
EMBO J.
, vol.15
, Issue.7
, pp. 1751
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
Chilov, D.4
Lahtinen, I.5
Kukk, E.6
Saksela, O.7
Kalkkinen, N.8
Alitalo, K.9
-
39
-
-
64249110579
-
Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity
-
19232345 10.1016/j.expneurol.2009.02.002 1:CAS:528:DC%2BD1MXkslKjsbc%3D
-
Hashioka S, Klegeris A, McGeer PL (2009) Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity. Exp Neurol 217:177-183
-
(2009)
Exp Neurol
, vol.217
, pp. 177-183
-
-
Hashioka, S.1
Klegeris, A.2
McGeer, P.L.3
-
40
-
-
2642641324
-
Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C
-
9525952 10.1074/jbc.273.14.8413
-
Ristimäki A, Narko K, Enholm B, Joukov V, Alitalo K (1998) Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J Biol Chem 273:8413-8418
-
(1998)
J Biol Chem
, vol.273
, pp. 8413-8418
-
-
Ristimäki, A.1
Narko, K.2
Enholm, B.3
Joukov, V.4
Alitalo, K.5
-
41
-
-
0030851721
-
Genomic organization of human and mouse genes for vascular endothelial growth factor C
-
9312130 10.1074/jbc.272.40.25176 1:CAS:528:DyaK2sXms1ehsbw%3D
-
Chilov D, Kukk E, Taira S, Jeltsch M, Kaukonen J, Palotie A, Joukov V, Alitalo K (1997) Genomic organization of human and mouse genes for vascular endothelial growth factor C. J Biol Chem 272:25176-25183
-
(1997)
J Biol Chem
, vol.272
, pp. 25176-25183
-
-
Chilov, D.1
Kukk, E.2
Taira, S.3
Jeltsch, M.4
Kaukonen, J.5
Palotie, A.6
Joukov, V.7
Alitalo, K.8
-
42
-
-
33846219169
-
Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes
-
17216674
-
Cha HS, Bae EK, Koh JH, Chai JY, Jeon CH, Ahn KS et al (2007) Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes. J Rheumatol 34:16-19
-
(2007)
J Rheumatol
, vol.34
, pp. 16-19
-
-
Cha, H.S.1
Bae, E.K.2
Koh, J.H.3
Chai, J.Y.4
Jeon, C.H.5
Ahn, K.S.6
-
43
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
14634646 10.1038/ni1013 1:CAS:528:DC%2BD3sXhtVWhtrzO
-
Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, Jeltsch M, Jackson DG, Talikka M, Rauvala H, Betsholtz C, Alitalo K (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5:74-80
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
Betsholtz, C.11
Alitalo, K.12
-
44
-
-
0032516528
-
Extracellular presence of IL-8 in the astrocyte-rich cultured cerebellar granule cells under acidosis
-
9749826 10.1016/S0024-3205(98)00365-8 1:CAS:528:DyaK1cXlsVCrtbc%3D
-
Watanabe Y, Miura I, Ohgami Y, Fujiwara M (1998) Extracellular presence of IL-8 in the astrocyte-rich cultured cerebellar granule cells under acidosis. Life Sci 63:1037-1046
-
(1998)
Life Sci
, vol.63
, pp. 1037-1046
-
-
Watanabe, Y.1
Miura, I.2
Ohgami, Y.3
Fujiwara, M.4
-
45
-
-
0032712997
-
Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic
-
10589791 1:CAS:528:DyaK1MXotV2gt7c%3D
-
Shi Q, Abbruzzese JL, Huang S, Fidler IJ, Xiong Q, Xie K (1999) Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin Cancer Res 5:3711-3721
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3711-3721
-
-
Shi, Q.1
Abbruzzese, J.L.2
Huang, S.3
Fidler, I.J.4
Xiong, Q.5
Xie, K.6
-
46
-
-
0034849755
-
Interleukin-8 and human cancer biology
-
11544106 10.1016/S1359-6101(01)00016-8 1:CAS:528:DC%2BD3MXmsFChtLg%3D
-
Xie K (2001) Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12:375-391
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 375-391
-
-
Xie, K.1
-
47
-
-
0034662635
-
Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells
-
10969814 1:CAS:528:DC%2BD3cXmsVahsLw%3D
-
Xu L, Fidler IJ (2000) Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells. Cancer Res 60:4610-4616
-
(2000)
Cancer Res
, vol.60
, pp. 4610-4616
-
-
Xu, L.1
Fidler, I.J.2
-
48
-
-
0032570596
-
Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation
-
9478960 10.1074/jbc.273.9.5086 1:CAS:528:DyaK1cXhs1Cgurc%3D
-
Bellocq A, Suberville S, Philippe C, Bertrand F, Perez J, Fouqueray B, Cherqui G, Baud L (1998) Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation. J Biol Chem 273:5086-5092
-
(1998)
J Biol Chem
, vol.273
, pp. 5086-5092
-
-
Bellocq, A.1
Suberville, S.2
Philippe, C.3
Bertrand, F.4
Perez, J.5
Fouqueray, B.6
Cherqui, G.7
Baud, L.8
-
49
-
-
2442560191
-
Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: Distribution and functional activity
-
14761893 10.1152/ajpcell.00407.2003 1:CAS:528:DC%2BD2cXkvFGjsrY%3D
-
Sennoune SR, Bakunts K, Martínez GM, Chua-Tuan JL, Kebir Y, Attaya MN, Martínez-Zaguilán R (2004) Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity. Am J Physiol Cell Physiol 286:C1443-C1452
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Sennoune, S.R.1
Bakunts, K.2
Martínez, G.M.3
Chua-Tuan, J.L.4
Kebir, Y.5
Attaya, M.N.6
Martínez-Zaguilán, R.7
-
50
-
-
38349114174
-
Plasmalemmal vacuolar H+-ATPases in angiogenesis, diabetes and cancer
-
18058006 10.1007/s10863-007-9108-8 1:CAS:528:DC%2BD1cXotlyktA%3D%3D
-
Sennoune SR, Martinez-Zaguilan R (2007) Plasmalemmal vacuolar H+-ATPases in angiogenesis, diabetes and cancer. J Bioenerg Biomembr 39:427-433
-
(2007)
J Bioenerg Biomembr
, vol.39
, pp. 427-433
-
-
Sennoune, S.R.1
Martinez-Zaguilan, R.2
-
51
-
-
36349001899
-
Targeting vacuolar H+-ATPases as a new strategy against cancer
-
18006801 10.1158/0008-5472.CAN-07-1805 1:CAS:528:DC%2BD2sXhtlSls7zK
-
Fais S, De Milito A, You H, Qin W (2007) Targeting vacuolar H+-ATPases as a new strategy against cancer. Cancer Res 67:10627-10630
-
(2007)
Cancer Res
, vol.67
, pp. 10627-10630
-
-
Fais, S.1
De Milito, A.2
You, H.3
Qin, W.4
-
53
-
-
67650236818
-
Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells
-
19366680 10.1074/jbc.M901201200 1:CAS:528:DC%2BD1MXmvFSjtL8%3D
-
Hinton A, Sennoune SR, Bond S, Fang M, Reuveni M, Sahagian GG, Jay D, Martinez-Zaguilan R, Forgac M (2009) Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells. J Biol Chem 284:16400-16408
-
(2009)
J Biol Chem
, vol.284
, pp. 16400-16408
-
-
Hinton, A.1
Sennoune, S.R.2
Bond, S.3
Fang, M.4
Reuveni, M.5
Sahagian, G.G.6
Jay, D.7
Martinez-Zaguilan, R.8
Forgac, M.9
-
54
-
-
0027069597
-
A plasma membrane V-type H(+)-ATPase may contribute to elevated intracellular pH (pHin) in some human tumor cells
-
1288345 10.1111/j.1749-6632.1992.tb43834.x
-
Martínez-Zaguilán R, Gillies RJ (1992) A plasma membrane V-type H(+)-ATPase may contribute to elevated intracellular pH (pHin) in some human tumor cells. Ann N Y Acad Sci 671:478-480
-
(1992)
Ann N y Acad Sci
, vol.671
, pp. 478-480
-
-
Martínez-Zaguilán, R.1
Gillies, R.J.2
-
55
-
-
77953463274
-
PH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
-
19876915 10.1002/ijc.25009
-
De Milito A, Canese R, Marino ML, Borghi M, Iero M, Villa A, Venturi G, Lozupone F, Iessi E, Logozzi M, Della Mina P, Santinami M, Rodolfo M, Podo F, Rivoltini L, Fais S (2010) pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity. Int J Cancer 127:207-219
-
(2010)
Int J Cancer
, vol.127
, pp. 207-219
-
-
De Milito, A.1
Canese, R.2
Marino, M.L.3
Borghi, M.4
Iero, M.5
Villa, A.6
Venturi, G.7
Lozupone, F.8
Iessi, E.9
Logozzi, M.10
Della Mina, P.11
Santinami, M.12
Rodolfo, M.13
Podo, F.14
Rivoltini, L.15
Fais, S.16
-
56
-
-
9744260934
-
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs
-
15547183 10.1093/jnci/djh305 1:CAS:528:DC%2BD2cXhtVSqsr%2FF
-
Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Iessi E, Parmiani G, Arancia G, Belardelli F, Fais S (2004) Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst 96:1702-1713
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1702-1713
-
-
Luciani, F.1
Spada, M.2
De Milito, A.3
Molinari, A.4
Rivoltini, L.5
Montinaro, A.6
Marra, M.7
Lugini, L.8
Logozzi, M.9
Lozupone, F.10
Federici, C.11
Iessi, E.12
Parmiani, G.13
Arancia, G.14
Belardelli, F.15
Fais, S.16
-
57
-
-
70350212812
-
Potential anti-inflammatory effects of proton pump inhibitors: A review and discussion of the clinical implications
-
Kedika RR, Souza RF, Spechler SJ (2009) Potential anti-inflammatory effects of proton pump inhibitors: a review and discussion of the clinical implications. Dig Dis Sci 54:2312-2317
-
(2009)
Dig Dis Sci
, vol.54
, pp. 2312-2317
-
-
Kedika, R.R.1
Souza, R.F.2
Spechler, S.J.3
-
58
-
-
84855451921
-
Low extracellular pH stimulates the production of IL-1β by human monocytes
-
22154780 10.1016/j.cyto.2011.11.013 1:CAS:528:DC%2BC38XlsVKqtg%3D%3D
-
Jancic CC, Cabrini M, Gabelloni ML, Rodríguez Rodrigues C, Salamone G, Trevani AS, Geffner J (2012) Low extracellular pH stimulates the production of IL-1β by human monocytes. Cytokine 57:258-268
-
(2012)
Cytokine
, vol.57
, pp. 258-268
-
-
Jancic, C.C.1
Cabrini, M.2
Gabelloni, M.L.3
Rodríguez Rodrigues, C.4
Salamone, G.5
Trevani, A.S.6
Geffner, J.7
-
59
-
-
34948843133
-
Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors
-
17122965 10.1007/s00011-006-6056-4 1:CAS:528:DC%2BD2sXmvFCnsQ%3D%3D
-
Handa O, Yoshida N, Fujita N, Tanaka Y, Ueda M, Takagi T et al (2006) Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors. Inflamm Res 55:476-480
-
(2006)
Inflamm Res
, vol.55
, pp. 476-480
-
-
Handa, O.1
Yoshida, N.2
Fujita, N.3
Tanaka, Y.4
Ueda, M.5
Takagi, T.6
|