The metabolisable hexoses D-glucose and D-mannose enhance the expression of IRS-2 but not of IRS-1 in pancreatic β-cells

Experimental and Clinical Endocrinology and Diabetes

Volumn 113, Issue 8, 2005, Pages 423-429

  Amacker Francoys I ^a   Mohanty, S ^a   Niessen, Markus ^a   Spinas, G A ^a   Trub T ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cells; Diabetes; IRS 2; Pancreatic islets

Indexed keywords

GLUCOSE; HEXOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MANNOSE;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CARBOHYDRATE METABOLISM; DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INSULIN-SECRETING CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MANNOSE; PHOSPHOPROTEINS; RATS; TRANSCRIPTION, GENETIC;

EID: 25444507156     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865803     Document Type: Article

References (37)

1. Alonso S, Minty A, Bourlet Y, Buckingham M. Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates. J Mol Evol 1986; 23: 11-22
2. Amasino RM. Acceleration of nucleic acid hybridization rate by polyethylene glycol. Anal Biochem 1986; 152: 304-307
3. Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 1992; 130: 167-178
4. Ashcroft SJ. Glucoreceptor mechanisms and the control of insulin release and biosynthesis. Diabetologia 1980; 18: 5-15
5. Ashcroft SJ, Weerasinghe LC, Randle PJ. Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. Biochem J 1973; 132: 223-231
6. Bernard-Kargar C, Ktorza A. Endocrine pancreas plasticity under physiological and pathological conditions. Diabetes 2001; 50 (Suppl 1): S30-S35
7. Bonner-Weir S. Islet growth and development in the adult. J Mol Endocrinol 2000; 24: 297-302
8. Bonner-Weir S, Deery D, Leahy JL, Weir GC. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 1989; 38: 49-53
9. Briaud I, Dickson LM, Lingohr MK, McCuaig JF, Lawrence JC, Rhodes CJ. IRS-2 proteasomal degradation mediated by a mTOR-induced negative feedback downregulates PKB-mediated signaling pathway in beta-cells. J Biol Chem 2004
10. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159
11. Cousin SP, Hügl SR, Myers JM, White MF, Reifel-Miller A, Rhodes CJ. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via Janus kinase 2 (JAK2)/ signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J 1999; 344: 649-658
12. Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Mossa-Basha M, White MF. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes. J Clin Invest 2003; 112: 1521-1532
13. Hoorens A, Van de CM, Klöppel G, Pipeleers D. Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest 1996; 98: 1568-1574
14. Hügl SR, White MF, Rhodes CJ. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem 1998; 273: 17771-17779
15. Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M. cAMP promotes pancreatic {beta}-cell survival via CREB-mediated induction of IRS2. Genes Dev 2003; 17: 1575-1580
16. Kekow J, Ulrichs K, Muller-Ruchholtz W, Gross WL. Measurement of rat insulin. Enzyme-linked immunosorbent assay with increased sensitivity, high accuracy, and greater practicability than established radioimmunoassay. Diabetes 1988; 37: 321-326
17. King DL, Chick WL. Pancreatic beta cell replication: effects of hexose sugars. Endocrinology 1976; 99: 1003-1009
18. King DL, Kitchen KC, Chick WL. Pancreatic beta-cell replication: relation to insulin secretion. Endocrinology 1978; 103: 1321-1327
19. Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes 2000; 49: 1880-1889
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685
21. Leahy JL, Weir GC. Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level. Diabetologia 1991; 34: 640-647
22. Ling Z, Kiekens R, Mahler T, Schuit FC, Pipeleers-Marichal M, Sener A, Kloppel G, Malaisse WJ, Pipeleers DG. Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells. Diabetes 1996; 45: 1774-1782
23. Liu K, Paterson AJ, Chin E, Kudlow JE. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death. Proc Natl Acad Sci USA 2000; 97: 2820-2825
24. Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY. Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 2001; 50: 1683-1690
25. Mohanty S, Spinas GA, Maedler K, Zuellig RA, Lehmann R, Donath MY, Trub T, Niessen M. Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis. Exp Cell Res 2005; 303: 68-78
26. Okazaki T, Ishikawa T, Nishimori S, Igarashi T, Hata K, Fujita T. Hyperosmolarity-induced gene stimulation is mediated by the negative calcium responsive element. J Biol Chem 1997; 272: 32274-32279
27. Oyadomari S, Araki E, Mori M. Endoplasmic reticulum stress-mediated apoptosis in pancreatic α-cells. Apoptosis 2002; 7: 335-345
28. Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306 (5695): 457-461
29. Pirola L, Johnston AM, Van Obberghen E. Modulation of insulin action. Diabetologia 2004; 47: 170-184
30. Ristow M, Mulder H, Pomplun D, Schulz T, Muller-Schmehl K, Krause A, Fex M, Puccio H, Muller J, Isken F, Spranger J, Muller-Wieland D, Magnuson MA, Mohlig M, Koenig M, Pfeiffer AFH. Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass. J Clin Invest 2003; 112: 527-534
31. Schuppin GT, Pons S, Hügl SR, Aiello LP, King GL, White MF, Rhodes CJ. A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth. Diabetes 1998; 47: 1074-1085
32. Sun XJ, Wang LM, Zhang Y, Yenush L, Myers MG Jr, Glasheen E, Lane WS, Pierce JH, White MF. Role of IRS-2 in insulin and cytokine signalling. Nature 1995; 377: 173-177
33. Swenne I. Pancreatic beta-cell growth and diabetes mellitus. Diabetologia 1992; 35: 193-201
34. Webster HV, Bone AJ, Webster KA, Wilkin TJ. Comparison of an enzyme-linked immunosorbent assay (ELISA) with a radioimmunoassay (RIA) for the measurement of rat insulin. J Immunol Methods 1990; 134: 95-100
35. Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF. IRS-2 coordinates IGF-1 receptor-mediated beta-cell development and peripheral insulin signalling. Nat Genet 1999; 23: 32-40
36. Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernai D, Pons S, Shulman GI, Bonner-Weir S, White MF. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 1998; 391: 900-904
37. Yamamoto T, Asano T, Mori A, Kumai C, Okumura M, Soji T. A rapid method for the separation of rat pancreatic islets from collagenase-digested pancreas using Percoll. Endocrinol Jpn 1981; 28: 563-567