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Volumn 11, Issue 2, 1997, Pages 251-262

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INSULIN; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 9;

EID: 0000772655     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.2.9885     Document Type: Article
Times cited : (128)

References (55)
  • 1
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger J, Ullrich A 1992 Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 2
    • 0026484261 scopus 로고
    • SH2 and SH3 domains: From structure to function
    • Pawson T, Gish GD 1992 SH2 and SH3 domains: from structure to function. Cell 71:359-362
    • (1992) Cell , vol.71 , pp. 359-362
    • Pawson, T.1    Gish, G.D.2
  • 3
    • 0023686033 scopus 로고
    • Signal transduction by allosteric receptor oligomerization
    • Schlessinger J 1988 Signal transduction by allosteric receptor oligomerization. Trends Biochem Sci 13:443-447
    • (1988) Trends Biochem Sci , vol.13 , pp. 443-447
    • Schlessinger, J.1
  • 5
    • 0026332810 scopus 로고
    • Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
    • Cunningham BC, Ultsch M, de Vos AM, Mulkerrin MG, Clauser KR, Wells JA 1992 Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 254:821-825
    • (1992) Science , vol.254 , pp. 821-825
    • Cunningham, B.C.1    Ultsch, M.2    De Vos, A.M.3    Mulkerrin, M.G.4    Clauser, K.R.5    Wells, J.A.6
  • 7
    • 0028582185 scopus 로고
    • Crystal structure of the tyrosine kinase domain of the human insulin receptor
    • Hubbard SR, Wei L, Ellis L, Hendrickson WA 1994 Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 372:746-754
    • (1994) Nature , vol.372 , pp. 746-754
    • Hubbard, S.R.1    Wei, L.2    Ellis, L.3    Hendrickson, W.A.4
  • 8
    • 0028157728 scopus 로고
    • The IRS-1 signaling system
    • White MF 1994 The IRS-1 signaling system. Curr Opin Genet Dev 4:47-54
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 47-54
    • White, M.F.1
  • 9
    • 0029135003 scopus 로고
    • New frontiers in insulin receptor substrate signaling
    • Myers Jr MG, White MF 1995 New frontiers in insulin receptor substrate signaling. Trends Endocrinol Metab 6:209-215
    • (1995) Trends Endocrinol Metab , vol.6 , pp. 209-215
    • Myers Jr., M.G.1    White, M.F.2
  • 12
    • 0027158159 scopus 로고
    • The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp
    • Kuhne MR, Pawson T, Lienhard GE, Feng GS 1993 The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp. J Biol Chem 268:11479-11481
    • (1993) J Biol Chem , vol.268 , pp. 11479-11481
    • Kuhne, M.R.1    Pawson, T.2    Lienhard, G.E.3    Feng, G.S.4
  • 14
    • 15844409347 scopus 로고    scopus 로고
    • The fyn tyrosine kinase binds IRS-1 and forms a distinct signaling complex during insulin stimulation
    • Sun XJ, Pons S, Asano T, Myers Jr MG, Glasheen EM, White MF 1996 The fyn tyrosine kinase binds IRS-1 and forms a distinct signaling complex during insulin stimulation. J Biol Chem 271:10583-10587
    • (1996) J Biol Chem , vol.271 , pp. 10583-10587
    • Sun, X.J.1    Pons, S.2    Asano, T.3    Myers Jr., M.G.4    Glasheen, E.M.5    White, M.F.6
  • 17
    • 0029923193 scopus 로고    scopus 로고
    • Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of GSBP p38 MAP kinase
    • McLaughlin MM, Kumar S, McDonnell PC, Van Horn S, Lee JC, Livi GP, Young PR 1996 Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of GSBP p38 MAP kinase. J Biol Chem 271:8488-8492
    • (1996) J Biol Chem , vol.271 , pp. 8488-8492
    • McLaughlin, M.M.1    Kumar, S.2    McDonnell, P.C.3    Van Horn, S.4    Lee, J.C.5    Livi, G.P.6    Young, P.R.7
  • 18
    • 0027958425 scopus 로고
    • Functional domains of the insulin receptor responsible for chemotactic signaling
    • Yenush L, Kundra V, White MF, Zetter BR 1994 Functional domains of the insulin receptor responsible for chemotactic signaling. J Biol Chem 269:100-104
    • (1994) J Biol Chem , vol.269 , pp. 100-104
    • Yenush, L.1    Kundra, V.2    White, M.F.3    Zetter, B.R.4
  • 19
    • 0028641601 scopus 로고
    • Association of insulin receptor substrate-1 with integrins
    • Vuori K, Ruoslahti E 1994 Association of insulin receptor substrate-1 with integrins. Science 266:1576-1578
    • (1994) Science , vol.266 , pp. 1576-1578
    • Vuori, K.1    Ruoslahti, E.2
  • 26
    • 0018186010 scopus 로고
    • Development of hormone receptors and hormone responsiveness in vitro
    • Rosen OM, Smith CJ, Fung C, Rubin CS 1978 Development of hormone receptors and hormone responsiveness in vitro. J Biol Chem 253:7579-7853
    • (1978) J Biol Chem , vol.253 , pp. 7579-7853
    • Rosen, O.M.1    Smith, C.J.2    Fung, C.3    Rubin, C.S.4
  • 27
    • 0025879715 scopus 로고
    • Isolation and characterization of the 160,000-Da phosphotyrosyl protein, a putative participant in insulin signaling
    • Keller SR, Kitagawa K, Aebersold RH, Lienhard GE, Garner CW 1991 Isolation and characterization of the 160,000-Da phosphotyrosyl protein, a putative participant in insulin signaling. J Biol Chem 266:12817-12820
    • (1991) J Biol Chem , vol.266 , pp. 12817-12820
    • Keller, S.R.1    Kitagawa, K.2    Aebersold, R.H.3    Lienhard, G.E.4    Garner, C.W.5
  • 29
    • 0028912448 scopus 로고
    • Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons
    • Zackenfels K, Oppenheim RW, Rohrer H 1995 Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons. Neuron 14:731-741
    • (1995) Neuron , vol.14 , pp. 731-741
    • Zackenfels, K.1    Oppenheim, R.W.2    Rohrer, H.3
  • 30
    • 0028430195 scopus 로고
    • From embryonal carcionoma cells to neurons: The P19 pathway
    • Bain G, Ray WJ, Yao M, Gottlieb DI 1994 From embryonal carcionoma cells to neurons: the P19 pathway. BioEssays 16:343-348
    • (1994) BioEssays , vol.16 , pp. 343-348
    • Bain, G.1    Ray, W.J.2    Yao, M.3    Gottlieb, D.I.4
  • 31
    • 0027174455 scopus 로고
    • Participation of tyrosine kinase in capping, internalization, and antigen presentation through membrane immunoglobulin in BAL17B lymphoma cells
    • Shimo K, Gyotoku Y, Arimitsu Y, Kakiuchi T, Mizuguchi J 1993 Participation of tyrosine kinase in capping, internalization, and antigen presentation through membrane immunoglobulin in BAL17B lymphoma cells. FEBS Lett 323:171-174
    • (1993) FEBS Lett , vol.323 , pp. 171-174
    • Shimo, K.1    Gyotoku, Y.2    Arimitsu, Y.3    Kakiuchi, T.4    Mizuguchi, J.5
  • 34
    • 0027969225 scopus 로고
    • Characterization of an interaction between insulin receptor substrate-1 and the insulin receptor by using the two-hybrid system
    • O'Neill TJ, Craparo A, Gustafson TA 1994 Characterization of an interaction between insulin receptor substrate-1 and the insulin receptor by using the two-hybrid system. Mol Cell Biol 14:6433-6442
    • (1994) Mol Cell Biol , vol.14 , pp. 6433-6442
    • O'Neill, T.J.1    Craparo, A.2    Gustafson, T.A.3
  • 35
    • 0028912999 scopus 로고
    • Phosphotyrosine-dependent interaction of She and IRS-1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain
    • Gustafson TA, He W, Craparo A, Schaub CD, O'Neill TJ 1995 Phosphotyrosine-dependent interaction of She and IRS-1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain. Mol Cell Biol 15:2500-2508
    • (1995) Mol Cell Biol , vol.15 , pp. 2500-2508
    • Gustafson, T.A.1    He, W.2    Craparo, A.3    Schaub, C.D.4    O'Neill, T.J.5
  • 36
    • 0029074148 scopus 로고
    • Non-SH2 domains within the insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor 1 receptor
    • Craparo A, O'Neill TJ, Gustafson TA 1995 Non-SH2 domains within the insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor 1 receptor. J Biol Chem 270:15639-15643
    • (1995) J Biol Chem , vol.270 , pp. 15639-15643
    • Craparo, A.1    O'Neill, T.J.2    Gustafson, T.A.3
  • 38
    • 0025735112 scopus 로고
    • A linkage map of mouse chromosome 8: Further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19
    • Howard TA, Rochelle JM, Saunders AM, Seldin MF 1991 A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19. Genomics 10:207-213
    • (1991) Genomics , vol.10 , pp. 207-213
    • Howard, T.A.1    Rochelle, J.M.2    Saunders, A.M.3    Seldin, M.F.4
  • 39
    • 0027164156 scopus 로고
    • Human skeletal muscle insulin receptor substrate-1: Characterization of the cDNA, gene and chromosomal localization
    • Araki E, Sun XJ, Haag BL, III, Zhang Y, Chuang LM, Yang-Feng T, White MF, Kahn CR 1993 Human skeletal muscle insulin receptor substrate-1: characterization of the cDNA, gene and chromosomal localization. Diabetes 42:1041-1054
    • (1993) Diabetes , vol.42 , pp. 1041-1054
    • Araki, E.1    Sun, X.J.2    Haag III, B.L.3    Zhang, Y.4    Chuang, L.M.5    Yang-Feng, T.6    White, M.F.7    Kahn, C.R.8
  • 40
    • 0027367546 scopus 로고
    • Amino acid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus
    • Almind K, Biorbaek C, Vestergaard H, Hansen T, Echwald SM, Pedersen O 1993 Amino acid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus. Lancet 342:828-832
    • (1993) Lancet , vol.342 , pp. 828-832
    • Almind, K.1    Biorbaek, C.2    Vestergaard, H.3    Hansen, T.4    Echwald, S.M.5    Pedersen, O.6
  • 41
    • 0027994029 scopus 로고
    • Insulin receptor substrate-1 variants in non-insulin-dependent diabetes
    • Laakso M, Malkki M, Kekalainen P, Kuusisto J, Deeb SS 1994 Insulin receptor substrate-1 variants in non-insulin-dependent diabetes. J Clin Invest 94:1141-1146
    • (1994) J Clin Invest , vol.94 , pp. 1141-1146
    • Laakso, M.1    Malkki, M.2    Kekalainen, P.3    Kuusisto, J.4    Deeb, S.S.5
  • 43
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budvari A, Ellis RW, White MF, Spiegelman BM 1996 IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance. Science 271:665-668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budvari, A.3    Ellis, R.W.4    White, M.F.5    Spiegelman, B.M.6
  • 45
    • 0023798826 scopus 로고
    • Two dominant-acting selectable markers for gene transfer studies in mammalian cells
    • Hartman SC, Mulligan RC 1988 Two dominant-acting selectable markers for gene transfer studies in mammalian cells. Proc Natl Acad Sci USA 85:8047-8051
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8047-8051
    • Hartman, S.C.1    Mulligan, R.C.2
  • 46
    • 0024352305 scopus 로고
    • Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats
    • Kahn BB, Charron MJ, Lodish HF, Cushman SW, Flier JS 1989 Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J Clin Invest 84:404-411
    • (1989) J Clin Invest , vol.84 , pp. 404-411
    • Kahn, B.B.1    Charron, M.J.2    Lodish, H.F.3    Cushman, S.W.4    Flier, J.S.5
  • 47
    • 0023705646 scopus 로고
    • Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity
    • Kahn BB, Simpson IA, Cushman SW 1988 Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity. J Clin Invest 82:691-699
    • (1988) J Clin Invest , vol.82 , pp. 691-699
    • Kahn, B.B.1    Simpson, I.A.2    Cushman, S.W.3
  • 48
    • 0000163138 scopus 로고
    • Analysis and cloning of eukaryotic genomic DNA
    • Cold Spring Harbor: Cold Spring Harbor Laboratory Press, NY
    • Sambrook J, Fritch EF, Maniatis T 1990 Analysis and cloning of eukaryotic genomic DNA. Molecular Cloning: A Laboratory Manual. ed 2. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, NY, 9, pp 9.1-9.62
    • (1990) Molecular Cloning: A Laboratory Manual. Ed 2 , vol.9 , pp. 91-962
    • Sambrook, J.1    Fritch, E.F.2    Maniatis, T.3
  • 49
    • 0026032128 scopus 로고
    • Development and applications of a molecular genetic linkage map of the mouse genome
    • Copeland NG, Jenkins NA 1991 Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet 7:113-118
    • (1991) Trends Genet , vol.7 , pp. 113-118
    • Copeland, N.G.1    Jenkins, N.A.2
  • 50
    • 0019949189 scopus 로고
    • Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus
    • Jenkins NA, Copeland NG, Taylor BA, Lee BK 1982 Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J Virol 43:26-36
    • (1982) J Virol , vol.43 , pp. 26-36
    • Jenkins, N.A.1    Copeland, N.G.2    Taylor, B.A.3    Lee, B.K.4
  • 53
    • 0024386366 scopus 로고
    • Conformational changes in the α- and β-subunits of the insulin receptor identified by anti-peptide antibodies
    • Perlman R, Bottaro DG, White MF, Kahn CR 1989 Conformational changes in the α- and β-subunits of the insulin receptor identified by anti-peptide antibodies. J Biol Chem 264:8946-8950
    • (1989) J Biol Chem , vol.264 , pp. 8946-8950
    • Perlman, R.1    Bottaro, D.G.2    White, M.F.3    Kahn, C.R.4
  • 54
    • 0026005158 scopus 로고
    • Preparation and use of antiphosphotyrosine antibodies to study structure and function of insulin receptors
    • White MF, Backer JM 1991 Preparation and use of antiphosphotyrosine antibodies to study structure and function of insulin receptors. Methods Enzymol (7):65-79
    • (1991) Methods Enzymol , Issue.7 , pp. 65-79
    • White, M.F.1    Backer, J.M.2


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