Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice

Diabetologia

Volumn 49, Issue 3, 2006, Pages 552-561

  Simmgen, M ^a   Knauf, C ^b   Lopez, M ^c   Choudhury, A I ^a   Charalambous, M ^a   Cantley, J ^a   Bedford, D C ^a   Claret, M ^a   Iglesias, M A ^b   Heffron, H ^a   Cani, P D ^b   Vidal Puig, A ^c   Burcelin, R ^b   Withers, D J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CNRS   (France)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Insulin receptor substrate protein; Insulin resistance; Insulin signalling; Liver

Indexed keywords

FAT; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 3BETA; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; LIPID; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLAMP; CONTROLLED STUDY; FAT INTAKE; GENE DELETION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HORMONE ACTION; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT GENE; LIPID ANALYSIS; LIPID DIET; LIPID METABOLISM; LIVER FUNCTION; LIVER METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMAL FEED; ANIMALS; GENE DELETION; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; LIVER; MICE; MICE, KNOCKOUT; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION;

EID: 33244459343     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-0084-4     Document Type: Article

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