Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca 2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells

Diabetes

Volumn 60, Issue 11, 2011, Pages 2892-2902

  Demozay, Damien ^a   Tsunekawa, Shin ^a   Briaud, Isabelle ^b   Shah, Ramila ^a   Rhodes, Christopher J ^a  

^a University of Chicago ^*  (United States)

^b Theriac Pharmaceutical Corp   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM ION; CYCLOSPORIN A; GLUCOSE; INSULIN RECEPTOR SUBSTRATE 2; NIFEDIPINE; TACROLIMUS; TRANSCRIPTION FACTOR NFAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; GENE EXPRESSION; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCINEURIN; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CELL LINE; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; NFATC TRANSCRIPTION FACTORS; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR; RNA, MESSENGER; TISSUE CULTURE TECHNIQUES;

EID: 80755168889     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0341     Document Type: Article

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