A systematic review of amyloid-β peptides as putative mediators of the association between affective disorders and Alzheimer's disease

Journal of Affective Disorders

Volumn 168, Issue , 2014, Pages 167-183

  Abbasowa, Leda ^a   Heegaard, Niels H H ^b,c  

^a Department of Medicine ^*  (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

Author keywords

Affective disorder; Alzheimer's disease; Amyloid ; Biomarkers; CSF; Plasma

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BIOLOGICAL MARKER;

ALZHEIMER DISEASE; BIPOLAR DISORDER; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID ANALYSIS; DEPRESSION; DIFFUSE LEWY BODY DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DYSTHYMIA; ETHNICITY; FRONTOTEMPORAL DEMENTIA; HUMAN; MAJOR DEPRESSION; MENTAL DISEASE; MILD COGNITIVE IMPAIRMENT; MOOD DISORDER; MULTIINFARCT DEMENTIA; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN METABOLISM; REVIEW; SYSTEMATIC REVIEW; COGNITION DISORDERS; COMPLICATION; METABOLISM;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BIOLOGICAL MARKERS; COGNITION DISORDERS; HUMANS; MOOD DISORDERS;

EID: 84904898191     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2014.06.050     Document Type: Review

References (150)

1. N. Adab, S.C. Tudur, J. Vinten, P. Williamson, and J. Winterbottom Common antiepileptic drugs in pregnancy in women with epilepsy Cochrane Database Syst. Rev. 3 2004 CD004848
2. A.C. Andreazza, M. Kauer-Sant'anna, B.N. Frey, D.J. Bond, F. Kapczinski, and L.T. Young et al. Oxidative stress markers in bipolar disorder: a meta-analysis J Affect. Disord. 111 2008 135 144
3. H. Baba, Y. Nakano, H. Maeshima, E. Satomura, Y. Kita, and T. Suzuki et al. Metabolism of amyloid-β protein may be affected in depression J. Clin. Psychiatry 73 2012 115 120
4. K. Bechter, H. Reiber, S. Herzog, D. Fuchs, H. Tumani, and H.G. Maxeiner Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction J. Psychiatr. Res. 44 2010 321 330
5. C. Bell, J. Abrams, and D. Nutt Tryptophan depletion and its implications for psychiatry Br. J. Psychiatry 178 2001 399 405 (Pubitemid 32436803)
6. G.E. Berrios, and J.I. Quemada Depressive illness in multiple sclerosis: clinical and theoretical aspects of the association Br. J. Psychiatry 156 1990 10 16 (Pubitemid 20028146)
7. J.L. Beyer, T. Young, M. Kuchibhatla, and K.R.R. Krishnan Hyperintense MRI lesions in bipolar disorder: a meta-analysis and review Int. Rev. Psychiatry 21 2009 394 409
8. M. Bibl, H. Esselmann, M. Otto, P. Lewczuk, L. Cepek, and E. Rüther et al. Cerebrospinal fluid amyloid β peptide patterns in Alzheimer's disease patients and non-demented controls depend on sample pretreatment: indication of carrier-mediated epitope masking of amyloid beta peptides Electrophoresis 25 2004 2912 2918 (Pubitemid 39294839)
9. M. Bibl, H. Esselmann, B. Mollenhauer, G. Weniger, V. Welge, and M. Liess et al. Blood-based neurochemical diagnosis of vascular dementia: a pilot study J. Neurochem. 103 2007 467 474 (Pubitemid 47498016)
10. M. Bibl, V. Welge, H. Esselmann, and J. Wiltfang Stability of amyloid-β peptides in plasma and serum Electrophoresis 33 2012 445 450
11. J.G. Biessels, S. Staekenborg, E. Brunner, C. Brayne, and P. Scheltens Risk of dementia in diabetes mellitus: a systematic review Lancet Neurol. 5 2006 64 74 (Pubitemid 41790697)
12. I. Blasko, W. Lederer, H. Oberbauer, T. Walch, G. Kemmler, and H. Hinterhuber et al. Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias Dement. Geriatr. Cognit. Disord. 21 2006 9 15 (Pubitemid 41797965)
13. I. Blasko, G. Kemmler, S. Jungwirth, I. Wichart, W. Krampla, and S. Weissgram et al. Plasma amyloid beta-42 independently predicts both late-onset depression and Alzheimer disease Am. J. Geriatr. Psychiatry 18 2010 973 982
14. K. Blennow, and H. Hampel CSF markers for incipient Alzheimer's disease Lancet Neurol. 2 2003 605 613 (Pubitemid 37162569)
15. E. Bora, B.J. Harrison, M. Yücel, and C. Pantelis Cognitive impairment in euthymic major depressive disorder: a meta-analysis Psychol. Med. 43 2013 2017 2026
16. K. Bordji, J. Becerril-Ortega, and A. Buisson Synapses, NMDA receptor activity and neuronal Aβ production in Alzheimer's disease Rev. Neurosci. 22 2011 285 294
17. M.A. Butters, W.E. Klunk, C.A. Mathis, J.C. Price, S.K. Ziolko, and J.A. Hoge et al. Imaging Alzheimer pathology in late-life depression with PET and Pittsburgh Compound-B Alzheimer Dis. Assoc. Disord. 22 2008 261 268
18. D. Carnevale, G. Mascio, I. D'Andrea, V. Fardella, R.D. Bell, and I. Branchi et al. Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature Hypertension 60 2012 188 197
19. N. Catteruccia, J. Willingale-Theune, D. Bunke, R. Prior, C.L. Masters, and A. Crisanti et al. Ultrastructural localization of the putative precursors of the A4 amyloid protein associated with Alzheimer's disease Am. J. Pathol. 137 1990 19 26 (Pubitemid 20229586)
20. L. Chami, and F. Checler BACE1 is at the crossroad of a toxic vicous cycle involving cellular stress and β-amyloid production in Alzheimer's disease Mol. Neurodegener. 7 2012 52
21. S. Champaneri, G.S. Wand, S.S. Malhotra, S.S. Casagrande, and S.H. Golden Biological basis of depression in adults with diabetes Curr. Diabetes Rep. 10 2010 396 405
22. M. Chen, N.C. Inestrosa, G.S. Ross, and H.L. Fernandez Platelets are the primary source of amyloid-peptide in human blood Biochem. Biophys. Res. Commun. 213 1995 96 103
23. S.A. Cosentino, Y. Stern, E. Sokolov, N. Scarmeas, J.J. Manly, and M.X. Tang et al. Plasma β-amyloid and cognitive decline Arch. Neurol. 67 2010 1485 1490
24. S. Craft, and G.S. Watson Insulin and neurodegenerative disease: shared and specific mechanisms Lancet Neurol. 3 2004 169 178 (Pubitemid 38229951)
25. D.G. Cruess, D.L. Evans, M.J. Repetto, D. Gettes, S.D. Douglas, and J.M. Petitto Prevalence, diagnosis, and pharmacological treatment of mood disorders in HIV disease Biol. Psychiatry 54 2003 307 316 (Pubitemid 37267860)
26. J.M. Czarna, G. Waldemar, and N.H.H. Heegaard Biochemical markers for Alzheimer disease Ugeskr. Laeger 168 2006 1010 1014
27. R. Deane, Y.S. Du, R.K. Submamaryan, B. LaRue, S. Jovanovic, and E. Hogg et al. RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain Nat. Med. 9 2003 907 913 (Pubitemid 36889934)
28. R. Deane, and B.V. Zlokovic Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease Curr. Alzheimer Res. 4 2007 191 197 (Pubitemid 46562394)
29. O.L. de Klerk, F.J. Bosker, A.T. Willemsen, A. Van Warde, A.K. Visser, and T. de Jager et al. Chronic stress and antidepressant treatment have opposite effects on P-glycoprotein at the blood-brain barrier: an experimental PET study in rats J. Psychopharmacol. 24 2010 1237 1242
30. C. Dickens, L. McGowan, D. Clark-Carter, and F. Creed Depression in rheumatoid arthritis: a systematic review of the literature with meta-analysis Psychosom. Med. 64 2002 52 60 (Pubitemid 34137399)
31. N. Direk, E.M.C. Schrijvers, R.F. de Bruijn, S. Mirza, A. Hofman, and M.A. Ikram et al. Plasma amyloid β, depression, and dementia in community-dwelling elderly J. Psychiatr. Res. 47 2013 479 485
32. J.E. Donahue, S.L. Flaherty, C.E. Johanson, J.A. Duncan, G.D. Silverberg, and M.C. Miller et al. RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease Acta Neuropathol. 112 2006 405 415 (Pubitemid 44469161)
33. P. Eikelenboom, E. van Exel, J.J. Hoozemans, R. Veerhuis, A.J. Rozemuller, and W.A. van Gool Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease Neurodegener. Dis. 7 2010 38 41
34. H. Englund, G.M. Degerman, R.M. Brundin, M. Hedlund, L. Kilander, and L. Lannfelt et al. Oligomerization partially explains the lowering of Aβ42 in Alzheimer's disease cerebrospinal fluid Neurodegener. Dis. 6 2009 139 147
35. B.S. Fernandes, C.S. Gama, K.M. Ceresér, L.N. Yatham, G.R. Fries, and G. Colpo et al. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis J. Psychiatr. Res. 45 2011 995 1004
36. R.A. Frank, D. Galasko, H. Hampel, J. Hardy, M.J. de Leon, and P.D. Mehta et al. Biological markers for therapeutic trials in Alzheimer's disease proceedings of the biological markers group; NIA initiative on neuroimaging in Alzheimer's disease Neurobiol. Aging 24 2003 521 536 (Pubitemid 36519160)
37. N. Fullwood, Y. Hayashi, and D. Allsop Plasma amyloid-beta concentrations in Alzheimer's disease: an alternative hypothesis Lancet Neurol. 5 2006 1000 1001 (Pubitemid 44709976)
38. S.A. Funke Detection of soluble amyloid-β oligomers and insoluble high-molecular-weight particles in CSF: development of methods with potential for diagnosis and therapy monitoring of Alzheimer's disease Int. J. Alzheimers Dis. 2011 2011 (Epub, November 2, ID 151645) 8 pp
39. G. Gelosa, and D.J. Brooks The prognostic value of amyloid imaging Eur. J. Nucl. Med. Mol. Imaging 39 2012 1207 1219
40. J. Ghiso, M. Shayo, M. Calero, D. Ng, Y. Tomidokoro, and S. Gandy et al. Systemic catabolism of Alzheimer's Abeta40 and Abeta42 J. Biol. Chem. 279 2004 45897 45908 (Pubitemid 39491582)
41. V. Giedraitis, J. Sundelöf, M.C. Irizarry, N. Gårevik, B.T. Hyman, and L.O. Wahlund et al. The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease Neurosci. Lett. 427 2007 127 131 (Pubitemid 47633799)
42. P. Gorwood, E. Corruble, B. Falissard, and G.M. Goodwin Toxic effects of depression on brain function: impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients Am. J. Psychiatry 165 2008 731 739 (Pubitemid 351810542)
43. L.A. Graff, J.R. Walker, and C.N. Bernstein Depression and anxiety in inflammatory bowel disease: a review of comorbidity and management Inflamm. Bowel Dis. 15 2009 1105 1118
44. T.C. Gualtieri, and L.G. Johnson Age-related cognitive decline in patients with mood disorders Prog. Neuro-Psychopharmacol. Biol. Psychiatry 32 2008 962 967 (Pubitemid 351622089)
45. P. Gudmundsson, I. Skoog, M. Waern, K. Blennow, S. Palsson, and L. Rosengren et al. The relationship between cerebrospinal fluid biomarkers and depression in elderly women Am. J. Geriatr. Psychiatry 15 2007 832 838
46. 42 activates the expression of BACE1 through the JNK pathway J. Alzheimers Dis. 27 2011 871 883
47. I.W. Hamley The amyloid beta peptide: a chemist's perspective. Role in Alzheimer's and fibrillization Chem. Rev. 112 2012 5147 5192
48. O. Hansson, H. Zetterberg, P. Buchhave, U. Andreasson, E. Londos, and L. Minthon et al. Prediction of Alzheimer's disease using the CSF Aβ42/Aβ40 ratio in patients with mild cognitive impairment Dement. Geriatr. Cognit. Disord. 23 2007 316 320 (Pubitemid 46631938)
49. J. Hertze, L. Minthon, H. Zetterberg, E. Vanmechelen, K. Blennow, and O. Hansson Evaluation of CSF biomarkers as predictors of Alzheimer's disease: a clinical follow-up study of 4.7 years J. Alzheimers Dis. 21 2010 1119 1128
50. R. Herzog, M.J. Alvarez-Pasquin, C. Diaz, J.L. Del Barrio, J.M. Estrada, and A. Gil Are healthcare workers' intentions to vaccinate related to their knowledge, beliefs and attitudes? A systematic review BMC Public Health 13 2013 154
51. C. Hock, S. Golombowski, F. Müller-Spahn, W. Naser, K. Beyreuther, and U. Mönning et al. Cerebrospinal fluid levels of amyloid precursor protein and amyloid β-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity Eur. Neurol. 39 1998 111 118 (Pubitemid 28069802)
52. A. Hofman, A. Ott, M.M. Breteler, M.L. Bots, A.J. Slooter, and F. van Harskamp et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia an Alzheimer's disease in the Rotterdam study Lancet 349 1997 151 154 (Pubitemid 27039193)
53. S. Hu, W.S. Sheng, L.C. Ehrlich, P.K. Peterson, and C.C. Chao Cytokine effects on glutamate uptake by human astrocytes Neuroimmunomodulation 7 2000 153 159 (Pubitemid 30204821)
54. M. Hölttä, O. Hansson, U. Andreasson, J. Hertze, L. Minthon, and K. Nägga et al. Evaluating amyloid-β oligomers in cerebrospinal fluid as a biomarker for Alzheimer's disease PLoS One 8 2013 e66381
55. B.A. Int'Veld, A. Ruitenberg, A. Hofman, L.J. Launer, C.M. van Duijn, and T. Stijnen et al. Nonsteroidal anti-inflammatory drugs and the risk of Alzheimer's disease N. Engl. J. Med. 345 2001 1515 1521 (Pubitemid 33144916)
56. M.C. Irrizary Biomarkers of Alzheimer disease in plasma NeuroRx 1 2004 226 234
57. N. Iwata, M. Higuchi, and C.S. Takaomi Metabolism of amyloid-β peptide and Alzheimer's disease Pharmacol. Ther. 108 2005 129 148 (Pubitemid 41527082)
58. J. Jakobsson, H. Zetterberg, K. Blennow, C.J. Ekman, A.G.M. Johansson, and M. Landén Altered concentrations of amyloid precursor protein metabolites in cerebrospinal fluid of patients with bipolar disorder Neuropsychopharmacology 38 2013 664 672
59. M. Jensen, J. Schröder, M. Blomberg, B. Engvall, J. Pantel, and N. Ida et al. Cerebrospinal fluid Aβ42 is increased early in sporadic Alzheimer's disease and declines with disease progression Ann. Neurol. 45 1999 504 511 (Pubitemid 29165817)
60. F. Kapczinski, F. Dal-Pizzol, A.L. Teixeira, P.V. Magalhaes, M. Kauer-Sant'Anna, and F. Klamt et al. Peripheral biomarkers and illness activity in bipolar disorder J. Pscyhiatr. Res. 45 2011 156 161
61. T. Kawarabayashi, and M. Shoji Plasma biomarkers of Alzheimer's disease Curr. Opin. Psychiatry 21 2008 260 267 (Pubitemid 351489346)
62. R.C. Kessler, S. Aguilar-Gaxiola, J. Alonso, S. Chatterji, S. Lee, and J. Ormel et al. The global burden of mental disorders: an update from the WHO World Mental Health Surveys Epidemiol. Psychiatr. Soc. 18 2009 23 33
63. Y. Kita, H. Baba, H. Maeshima, Y. Nakano, T. Suzuki, and H. Arai Serum amyloid β protein in young and elderly depression: a pilot study Psychogeriatrics 9 2009 180 185
64. A. Koyama, O.I. Okereke, T. Yang, D. Blacker, D.J. Selkoe, and F. Grodstein Plasma Amyloid-β as a predictor of dementia and cognitive decline Arch. Neurol. 69 2012 824 831
65. M.G. Kramberger, V. Jelic, I. Kåreholt, D. Enache, J.M. Eriksdotter, and B. Winblad et al. Cerebrospinal fluid Alzheimer markers in depressed elderly subjects with and without Alzheimer's disease Dement. Geriatr. Cognit. Disord. Extra 2 2012 48 56
66. K.T. Kronmüller, J. Pantel, S. Köhler, D. Victor, F. Giesel, and V.A. Magnotta et al. Hippocampal volume and 2-year outcome in depression Br. J. Psychiatry 192 2008 472 473 (Pubitemid 351809903)
67. Y.M. Kuo, M.R. Emmerling, H.C. Lampert, S.R. Hempelman, T.A. Kokjohn, and A.S. Woods et al. High levels of circulating Aβ42 are sequestered by plasma proteins in Alzheimer's disease Biochem. Biophys. Res. Commun. 257 1999 787 791 (Pubitemid 29301519)
68. Y.M. Kuo, T.A. Kokjohn, W. Kalback, D. Luehrs, D.R. Galasko, and N. Chevallier et al. Amyloid-β peptides interact with plasma proteins and erythrocytes: implications for their quantification in plasma Biochem. Biophys. Res. Commun. 268 2000 750 756 (Pubitemid 30150863)
69. T.M. Lauersen, T. Munk-Olsen, M. Nordentoft, and P.B. Mortensen Increased mortality among patients admitted with major psychiatric disorders: a register-based study comparing mortality in unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia J. Clin. Psychiatry 68 2007 899 907 (Pubitemid 47015490)
70. S. Lesne, C. Ali, C. Gabriel, N. Croci, E.T. MacKenzie, and C.G. Glabe et al. NMDA receptor activation inhibits α-secretase and promotes neuronal amyloid β production J. Neurosci. 25 2005 9367 9377 (Pubitemid 41464749)
71. P. Lewczuk, G. Beck, H. Esselmann, R. Bruckmoser, R. Zimmermann, and M. Fiszer et al. Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid β peptides Clin. Chem. 52 2006 332 334 (Pubitemid 43185505)
72. A. Liaudet-Perret, M. Pelpel, Y. Tholance, B. Dumont, H. Vanderstichele, and W. Zorzi et al. Risk of Alzheimer's disease biological misdiagnosis linked to cerebrospinal collection tubes J. Alzheimers Dis. 31 2012 13 20
73. G.P. Lim, F. Yang, T. Chu, P. Chen, W. Beech, and B. Teter et al. Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease J. Neurosci. 20 2000 5709 5714 (Pubitemid 30636898)
74. G. Lippi, M. Motagnana, E.J. Favaloro, and M. Francini Mental depression and cardiovascular disease: a multifaceted, bidirectional association Semin. Thromb. Hemost. 35 2009 325 336
75. Y. Liu, R.C. Ho, and A. Mak Interleukin(IL)-6, tumor necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and metaregression J. Affect. Disord. 139 2012 230 239
76. J.A. Luchsinger, M.X. Tang, Y. Stern, S. Shea, and R. Mayeux Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort Am. J. Epidemiol. 154 2001 635 641 (Pubitemid 32888781)
77. 11C)PiB binding Neurobiol. Aging 33 2012 2334 2342
78. M. Maes, P. Galecki, Y.S. Chang, and M. Berk A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness Prog. Neuropsychopharmacol. Biol. Psychiatry 35 2011 676 692
79. F. Mangialasche, M.C. Polidori, R. Monastero, S. Ercolani, C. Camarda, and R. Cecchetti et al. Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment Ageing Res. Rev. 8 2009 285 305
80. 1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells Neurosci. Lett. 401 2006 219 224 (Pubitemid 44250979)
81. M.A. Marques, J.J. Kulstad, C.E. Savard, P.S. Green, S.P. Lee, and S. Craft et al. Peripheral amyloid-β levels regulate amyloid-β clearence from the central nervous system J. Alzheimers Dis. 16 2009 325 329
82. A. Martinez-Aran, C. Torrent, R. Tabares-Seisdedos, M. Salamero, C. Daban, and V. Balanza-Martinez et al. Neurocognitive impairment in bipolar patients with and without a history of psychosis J. Clin. Psychiatry 69 2008 233 239 (Pubitemid 351469266)
83. G. Masi, and P. Brovedan The hippocampus, neurotrophic factors and depression CNS Drugs 25 2011 913 931
84. R. Mayeux, L.S. Honig, M.X. Tang, J. Manly, Y. Stern, and N. Schupf et al. Plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk Neurology 61 2003 1185 1190 (Pubitemid 37377535)
85. A.L. Metti, J.A. Cauley, A.B. Newman, H.N. Ayonayon, L.C. Barry, and L.M. Kuller et al. Plasma beta amyloid level and depression in older adults J. Gerontol. A: Biol. Sci. Med. Sci. 68 2013 74 79
86. Y.S. Moon, S.H. Kang, H.J. No, M.H. Won, S.B. Ki, and S.K. Lee et al. The correlation of plasma Aβ42 levels, depressive symptoms, and cognitive function in the Korean elderly Prog. Neuropsychopharmacol. Biol. Psychiatry 35 2011 1603 1606
87. R.E. Mrak, and W.S. Griffin Potential inflammatory biomarkers in Alzheimer's disease J. Alzheimers Dis. 8 2005 369 375
88. R.E. Mrak, J.G. Sheng, and W.S. Griffin Glial cytokines in Alzheimer's disease: review and pathogenic implications Hum. Pathol. 26 1995 816 823
89. D.L. Musselman, D.L. Evans, and C.B. Nemeroff The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment Arch. Gen. Psychiatry 55 1998 580 592 (Pubitemid 28340345)
90. A.M. Myint, M.J. Schwartz, H.W. Steinbusch, and B.E. Leonard Neuropsychiatric disorders related to interferon and interleukins treatment Metab. Brain Dis. 24 2009 55 68
91. Y. Namekawa, H. Baba, H. Maeshima, Y. Nakano, E. Satomura, and N. Takebayashi et al. Heterogeneity of elderly depression: Increased risk of Alzheimer's disease and Aβ protein metabolism Prog. Neuro-Psychopharmacol. Biol. Psychiatry 43 2013 203 208
92. R.L. Nelson, Z. Guo, V.M. Halagappa, M. Pearson, A.J. Gray, and Y. Matsuoka et al. Prophylactic treatment with paroxetine ameliorates behavioural deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice Exp. Neurol. 205 2007 166 176 (Pubitemid 46617502)
93. J.C. O'Connor, C. André, Y. Wang, M.A. Lawson, S.S. Szegedi, and J. Lestage et al. Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin J. Neurosci. 29 2009 4200 4209
94. R.L. Ownby, E. Crocco, A. Acevedo, V. John, and D. Loewenstein Depression and risk for Alzheimer disease Arch. Gen. Psychiatry 63 2006 530 538
95. T.W.W. Pace, F. Hu, and A.H. Miller Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression Brain Behav. Immun. 21 2007 9 19 (Pubitemid 44872932)
96. M. Pakaski, A. Bjelik, M. Hugyecz, P. Kasa, Z. Janka, and J. Kálmán Imipramine and citalopram facilitate amyloid precursor protein secretion in vitro Neurochem. Int. 47 2005 190 195 (Pubitemid 40848681)
97. J.A. Pasco, G.C. Nicholson, L.J. Williams, F.N. Jacka, M.J. Henry, and M.A. Kotowicz et al. Association of high-sensitivity C-reactive protein with de novo major depression Br. J. Psychiatry 197 2010 372 377
98. A. Piccinni, N. Origlia, A. Veltri, C. Vizzacaro, D. Marazziti, and M. Catena-Dell'osso et al. Plasma β-amyloid peptide levels: a pilot study in bipolar depressed patients J Affect. Disord. 138 2012 160 164
99. K.E. Pike, G. Savage, V.L. Villemagne, S. Ng, S.A. Moss, and P. Maruff et al. Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease Brain 130 2007 2837 2844 (Pubitemid 350033975)
100. N. Pomara, and P. Doraiswamy Does increased platelet release of Abeta peptide contribute to brain abnormalities in individuals with depression? Med. Hypotheses 60 2003 640 643 (Pubitemid 36399291)
101. N. Pomara, L.M. Willoughby, J.J. Sidtis, and P.D. Mehta Selective reductions in plasma Aβ 1-42 in healthy elderly subjects during longitudinal follow-up Am. J. Geriatr. Psychiatry 13 2005 914 917 (Pubitemid 46638681)
102. N. Pomara, P.M. Doraiswamy, L.M. Willoughby, A.E. Roth, B.H. Mulsant, and J.J. Sidtis et al. Elevation in plasma Abeta42 in geriatric depression: a pilot study Neurochem. Res. 31 2006 341 349 (Pubitemid 43829323)
103. N. Pomara, D. Bruno, A.S. Sarreal, R.T. Hernando, J. Nierenberg, and E. Petkova et al. Lower CSF amyloid beta peptides and higher F2-isoprostanes in cognitively intact elderly individuals with major depressive disorder Am. J. Psychiatry 169 2012 523 530
104. E. Portelius, U. Andreasson, J.M. Ringman, K. Buerger, J. Daborg, and P. Buchhave et al. Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer disease Mol. Neurodegener. 5 2010 2
105. A. Post, N. Ackl, M. Rücker, Y. Schreiber, E.B. Binder, and M. Ising et al. Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression Biol. Psychiatry 59 2006 858 862
106. H. Qing, G. He, P.T. Ly, C.J. Fox, M. Staufenbiel, and F. Cai et al. Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models J. Exp. Med. 205 2008 2781 2789
107. W.Q. Qiu, X. Sun, D.J. Selkoe, D.M. Mwamburi, T. Huang, and R. Bhadela et al. Depression is associated with low plasma Aβ42 independently of cardiovascular disease in the homebound elderly Int. J. Geriatr. Psychiatry 22 2007 536 542 (Pubitemid 46951751)
108. G.D. Rabinovici, and W.J. Jagust Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo Behav. Neurol. 21 2009 117 128
109. C.L. Raison, L. Capuron, and A.H. Miller Cytokines sing the blues: inflammation and the pathogenesis of depression Trends Immunol. 27 2006 24 31 (Pubitemid 43083561)
110. K. Rees, R. Stowe, S. Patel, N. Ives, K. Breen, and C.E. Clarke et al. Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies Cochrane Database Syst. Rev. 11 2011 CD008454
111. T. Reis, C.O. Brandao, E.S.F. Coutinho, E. Engelhardt, and J. Laks Cerebrospinal fluid biomarkers in Alzheimer's disease and geriatric depression: preliminary findings from Brazil CNS Neurosci. Ther. 18 2012 524 529
112. T.J. Revett, G.B. Baker, J. Jhamandas, and S. Kar Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology J. Psychiatry Neurosci. 38 2013 6 23
113. Zoltan Rihmer Suicide risk in mood disorders Curr. Opin. Psychiatry 20 2007 17 22 (Pubitemid 44901071)
114. L.J. Robinson, J.M. Thompson, P. Gallagher, U. Goswami, A.H. Young, and I.N. Ferrier et al. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder J. Affect. Disord. 93 2006 105 115 (Pubitemid 43816055)
115. A.E. Roher, C.L. Esh, T.A. Kokjohn, E.M. Castano, G.D. Van Vickle, and W.M. Kalback et al. Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease Alzheimers Dement. 5 2009 18 29
116. A. Sagare, R. Deane, R.D. Bell, B. Johnson, K. Hamm, and R. Pendu et al. Clearance of amyloid-beta by circulating lipoprotein receptors Nat. Med. 13 2007 1029 1031 (Pubitemid 47517512)
117. A.N. Santos, M. Ewers, L. Minthon, A. Simm, R.E. Silber, and K. Blennow et al. Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease J. Alzheimers Dis. 29 2012 171 176
118. P. Scheltens, N. Fox, F. Barkhof, and C. De Carli Structural magnetic resonance imaging in the practical assessment of dementia: beyond exclusion Lancet Neurol. 1 2002 13 21 (Pubitemid 37159194)
119. O.J.G. Schiepers, M.C. Wichers, and M. Maes Cytokines and major depression Prog. Neuropsychopharmacol. Biol. Psychiatry 29 2005 201 217 (Pubitemid 40202906)
120. J. Schröder, J. Pantel, N. Ida, M. Essig, T. Hartmann, and M.V. Knopp et al. Cerebral changes and cerebrospinal fluid β-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging Mol. Psychiatry 2 1997 505 507
121. R.A. Shih, P.L. Belmonte, and P.P. Zandi A review of the evidence from family, twin and adoption studies for a genetic contribution to adult psychiatric disorders Int. Rev. Psychiatry 16 2004 260 283 (Pubitemid 39657837)
122. M. Shoji, and M. Kanai Cerebrospinal fluid Aβ40 and Aβ42: natural course and clinical usefulness J. Alzheimers Dis. 3 2001 313 321 (Pubitemid 32577635)
123. G.E. Simon Social and economic burden of mood disorders Biol. Psychiatry 54 2003 208 215 (Pubitemid 37267852)
124. 1-42 and GAP-43 in frontotemporal dementia, other types of dementia and normal aging J. Neural Transm. 107 2000 563 579 (Pubitemid 30251740)
125. I. Skoog, B. Lernfelt, S. Landahl, B. Palmertz, L.A. Andreasson, and L. Nilsson et al. 15-Year longitudinal study of blood pressure and dementia Lancet 347 1996 1141 1145 (Pubitemid 126512042)
126. D.A. Solomon, M.B. Keller, A.C. Leon, T.I. Mueller, P.W. Lavori, and M.T. Shea et al. Multiple recurrences of major depressive disorder Am. J. Psychiatry 157 2000 229 233 (Pubitemid 30080902)
127. D. Spiegel, and J. Giese-Davis Depression and cancer: mechanisms and disease progression Biol. Psychiatry 54 2003 269 282 (Pubitemid 37267857)
128. D. Stellwagen, E.C. Beattie, J.Y. Seo, and R.C. Malenka Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-alpha J. Neurosci. 25 2005 3219 3228 (Pubitemid 40463557)
129. C. Stenh, H. Englund, A. Lord, A.S. Johansson, C.G. Almeida, and P. Gellerfors et al. Amyloid-β oligomers are inefficiently measured by enzyme-linked immunosorbant assay Ann. Neurol. 58 2005 147 150 (Pubitemid 40962471)
130. X. Sun, S. Sato, O. Murayama, M. Murayama, J.M. Park, and H. Yamaguchi et al. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein c100 Neurosci. Lett. 321 2002 61 64 (Pubitemid 34185499)
131. X. Sun, D.M. Mwamburi, K. Bungay, J. Prasad, J. Yee, and Y.M. Lin et al. Depression, antidepressants, and plasma amyloid β (beta) peptides in those elderly who do not have cardiovascular disease Biol. Psychiatry 62 2007 1413 1417 (Pubitemid 350180722)
132. X. Sun, D.C. Steffens, R. Au, M. Folstein, P. Summergrad, and J. Yee et al. Amyloid-associated depression: a prodromal depression of Alzheimer disease? Arch. Gen. Psychiatry 65 2008 542 550 (Pubitemid 351645050)
133. X. Sun, C.C. Chiu, E. Liebson, N.A. Crivello, L. Wang, and J. Claunch et al. Depression and plasma amyloid β peptides in the elderly with and without the apolipoprotein E4 allele Alzheimer Dis. Assoc. Disord. 23 2009 238 244
134. X. Sun, R. Bhadelia, E. Liebson, P. Bergethon, M. Folstein, and J.J. Zhu et al. The relationship between plasma amyloid-β peptides and the medial temporal lobe in the homebound elderly Int. J. Geriatr. Psychiatry 26 2011 593 601
135. C.A. Szekely, J.E. Thorne, P.P. Zandi, M. Ek, E. Messias, and J.C. Breitner et al. Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review Neuroepidemiology 23 2004 159 169 (Pubitemid 38980441)
136. M. Tabaton, and E. Tamagno The molecular link between β- and γ-secretase activity on the amyloid β precursor protein Cell. Mol. Life Sci. 64 2007 2211 2218 (Pubitemid 47347960)
137. E. Tamagno, M. Guglielmotto, M. Aragno, R. Borghi, R. Autelli, and L. Giliberto et al. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein J. Neurochem 104 2008 683 695
138. W.D. Taylor, H.J. Aizenstein, and G.S. Alexopoulos The vascular depression hypothesis: mechanisms linking vascular disease with depression Mol. Psychiatry 18 2013 963 974
139. M.W. Tham, P.S. Woon, M.Y. Sum, T.S. Lee, and K. Sim White matter abnormalities in depression: evidence from post-mortem, neuroimaging and genetic studies J. Affect. Disord. 132 2011 26 36
140. H. Vanderstichele, M. Bibl, S. Engelborghs, N. Le Bastard, P. Lewczuk, and J.L. Molinuevo et al. Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative Alzheimers Dement. 8 2012 65 73
141. V.L. Villemagne, S. Burnham, P. Bourgeat, P. Brown, K.A. Ellis, and O. Salvado et al. Amyloid beta deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study Lancet Neurol. 12 2013 357 367
142. B. Viviani, S. Bartesaghi, F. Gardoni, A. Vezzani, M.M. Behrens, and T. Bartfai et al. Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases J Neurosci. 23 2003 8692 8700 (Pubitemid 37176649)
143. V. Welge, O. Fiege, P. Lewczuk, B. Mollenhauer, H. Esselmann, and H.W. Klafki et al. Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer's disease J Neural Transm. 116 2009 203 212
144. Wells, G.A., Shea, B., O'Connell, D., Peterson, J., Welch, V., Losos, M., et al., 2013. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Non-randomized Studies in Meta-analyses. http://www.ohri.ca/programs/clinical- epidemiology/oxford.asp, September.
145. 18F-florbetapir (AV-45/Amyvid) positron emission tomography Eur. J. Nucl. Med. Mol. Imaging 41 2014 714 722
146. W. Xia, T. Yang, G. Shankar, I.M. Smith, Y. Shen, and D.M. Walsh et al. A specific enzyme-linked immunosorbant assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease Arch. Neurol. 66 2009 190 199
147. Q. Yang, J. Zhang, H. Liu, S. Babu-Khan, R. Vassar, and A.L. Biere et al. Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease J. Neurosci. 23 2003 7504 7509 (Pubitemid 37034066)
148. H. Zetterberg Is plasma Amyloid-β a reliable biomarker for Alzheimer's disease Recent Pat. CNS Drug Discov. 3 2008 109 111
149. L. Zhou, K.H. Chan, L.W. Chu, J.S. Kwan, Y.Q. Song, and L.H. Chen et al. Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis Biochem. Biophys. Res. Commun. 23 2012 697 702
150. J.K. Zubieta, P. Huguelet, R.L. O'Neil, and B.J. Giodani Cognitive function in euthymic bipolar I disorder Psychiatry Res. 102 2001 9 20 (Pubitemid 32463920)