Amyloid-β42 activates the expression of BACE1 through the JNK pathway

Journal of Alzheimer's Disease

Volumn 27, Issue 4, 2011, Pages 871-883

  Guglielmotto, Michela ^a   Monteleone, Debora ^a   Giliberto, Luca ^b   Fornaro, Michele ^c   Borghi, Roberta ^c   Tamagno, Elena ^a   Tabaton, Massimo ^d  

^a UNIVERSITY OF TURIN   (Italy)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Alzheimer's disease; BACE1; JNK c jun pathway; secretase

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; GAMMA SECRETASE; PROTEIN C JUN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; ENZYME INHIBITOR; PEPTIDE FRAGMENT; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; MALE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; C57BL MOUSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MUTATION; NEUROBLASTOMA; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CELL LINE, TUMOR; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEUROBLASTOMA; PEPTIDE FRAGMENTS; TRANSFECTION;

EID: 84455193364     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110884     Document Type: Article

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