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Volumn 427, Issue 3, 2007, Pages 127-131

The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease

Author keywords

Alzheimer's disease; Amyloid beta; APOE; Case control studies; Cerebrospinal fluid; Mild cognitive impairment (MCI)

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E;

EID: 35448942648     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.09.023     Document Type: Article
Times cited : (116)

References (27)
  • 2
    • 0036355751 scopus 로고    scopus 로고
    • Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine
    • Basun H., Nilsberth C., Eckman C., Lannfelt L., and Younkin S. Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine. Dement. Geriatr. Cogn. Disord. 14 (2002) 156-160
    • (2002) Dement. Geriatr. Cogn. Disord. , vol.14 , pp. 156-160
    • Basun, H.1    Nilsberth, C.2    Eckman, C.3    Lannfelt, L.4    Younkin, S.5
  • 3
    • 7444253126 scopus 로고    scopus 로고
    • Cerebrospinal fluid protein biomarkers for Alzheimer's disease
    • Blennow K. Cerebrospinal fluid protein biomarkers for Alzheimer's disease. NeuroRx 1 (2004) 213-225
    • (2004) NeuroRx , vol.1 , pp. 213-225
    • Blennow, K.1
  • 4
    • 0036319503 scopus 로고    scopus 로고
    • Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease
    • DeMattos R.B., Bales K.R., Parsadanian M., O'Dell M.A., Foss E.M., Paul S.M., and Holtzman D.M. Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease. J. Neurochem. 81 (2002) 229-236
    • (2002) J. Neurochem. , vol.81 , pp. 229-236
    • DeMattos, R.B.1    Bales, K.R.2    Parsadanian, M.3    O'Dell, M.A.4    Foss, E.M.5    Paul, S.M.6    Holtzman, D.M.7
  • 5
    • 0029886811 scopus 로고    scopus 로고
    • The Clinical Dementia Rating scale: community-based validation of "profound' and "terminal' stages
    • Dooneief G., Marder K., Tang M.X., and Stern Y. The Clinical Dementia Rating scale: community-based validation of "profound' and "terminal' stages. Neurology 46 (1996) 1746-1749
    • (1996) Neurology , vol.46 , pp. 1746-1749
    • Dooneief, G.1    Marder, K.2    Tang, M.X.3    Stern, Y.4
  • 6
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau/beta-amyloid42 ratio as a prediction of cognitive decline in nondemented older adults
    • Fagan A.M., Roe C.M., Xiong C., Mintun M.A., Morris J.C., and Holtzman D.M. Cerebrospinal fluid tau/beta-amyloid42 ratio as a prediction of cognitive decline in nondemented older adults. Arch. Neurol. 64 (2007) 343-349
    • (2007) Arch. Neurol. , vol.64 , pp. 343-349
    • Fagan, A.M.1    Roe, C.M.2    Xiong, C.3    Mintun, M.A.4    Morris, J.C.5    Holtzman, D.M.6
  • 7
    • 0036233168 scopus 로고    scopus 로고
    • Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease
    • Fagan A.M., Watson M., Parsadanian M., Bales K.R., Paul S.M., and Holtzman D.M. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 9 (2002) 305-318
    • (2002) Neurobiol. Dis. , vol.9 , pp. 305-318
    • Fagan, A.M.1    Watson, M.2    Parsadanian, M.3    Bales, K.R.4    Paul, S.M.5    Holtzman, D.M.6
  • 9
    • 15244340676 scopus 로고    scopus 로고
    • Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model
    • Fryer J.D., Simmons K., Parsadanian M., Bales K.R., Paul S.M., Sullivan P.M., and Holtzman D.M. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. J. Neurosci. 25 (2005) 2803-2810
    • (2005) J. Neurosci. , vol.25 , pp. 2803-2810
    • Fryer, J.D.1    Simmons, K.2    Parsadanian, M.3    Bales, K.R.4    Paul, S.M.5    Sullivan, P.M.6    Holtzman, D.M.7
  • 11
    • 0030035294 scopus 로고    scopus 로고
    • Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries
    • Ghersi-Egea J.F., Gorevic P.D., Ghiso J., Frangione B., Patlak C.S., and Fenstermacher J.D. Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J. Neurochem. 67 (1996) 880-883
    • (1996) J. Neurochem. , vol.67 , pp. 880-883
    • Ghersi-Egea, J.F.1    Gorevic, P.D.2    Ghiso, J.3    Frangione, B.4    Patlak, C.S.5    Fenstermacher, J.D.6
  • 12
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • Hixson J.E., and Vernier D.T. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J. Lipid Res. 31 (1990) 545-548
    • (1990) J. Lipid Res. , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 14
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., and Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21 (2001) 372-381
    • (2001) J. Neurosci. , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 15
    • 1642296212 scopus 로고    scopus 로고
    • Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-l-alaninamide (LY-411575)
    • Lanz T.A., Hosley J.D., Adams W.J., and Merchant K.M. Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-l-alaninamide (LY-411575). J. Pharmacol. Exp. Ther. 309 (2004) 49-55
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 49-55
    • Lanz, T.A.1    Hosley, J.D.2    Adams, W.J.3    Merchant, K.M.4
  • 17
    • 33947614736 scopus 로고    scopus 로고
    • Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-beta protein transport across the blood-brain barrier in Alzheimer's disease
    • Matsumoto Y., Yanase D., Noguchi-Shinohara M., Ono K., Yoshita M., and Yamada M. Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-beta protein transport across the blood-brain barrier in Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 23 (2007) 241-245
    • (2007) Dement. Geriatr. Cogn. Disord. , vol.23 , pp. 241-245
    • Matsumoto, Y.1    Yanase, D.2    Noguchi-Shinohara, M.3    Ono, K.4    Yoshita, M.5    Yamada, M.6
  • 18
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology 34 (1984) 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 19
    • 33744503967 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid A beta38/A beta42 ratio in Alzheimer disease
    • Mehta P.D., and Pirttila T. Increased cerebrospinal fluid A beta38/A beta42 ratio in Alzheimer disease. Neurodegener. Dis. 2 (2005) 242-245
    • (2005) Neurodegener. Dis. , vol.2 , pp. 242-245
    • Mehta, P.D.1    Pirttila, T.2
  • 20
    • 0035907123 scopus 로고    scopus 로고
    • Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease
    • Mehta P.D., Pirttila T., Patrick B.A., Barshatzky M., and Mehta S.P. Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease. Neurosci. Lett. 304 (2001) 102-106
    • (2001) Neurosci. Lett. , vol.304 , pp. 102-106
    • Mehta, P.D.1    Pirttila, T.2    Patrick, B.A.3    Barshatzky, M.4    Mehta, S.P.5
  • 25
    • 21044447551 scopus 로고    scopus 로고
    • Plasma levels of alpha beta peptides are altered in amnestic mild cognitive impairment but not in sporadic Alzheimer's disease
    • Sobow T., Flirski M., Kloszewska I., and Liberski P.P. Plasma levels of alpha beta peptides are altered in amnestic mild cognitive impairment but not in sporadic Alzheimer's disease. Acta. Neurobiol. Exp. (Wars) 65 (2005) 117-124
    • (2005) Acta. Neurobiol. Exp. (Wars) , vol.65 , pp. 117-124
    • Sobow, T.1    Flirski, M.2    Kloszewska, I.3    Liberski, P.P.4
  • 27


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.