-
1
-
-
0037052544
-
Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes
-
Rulifson E.J., Kim S.K., Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science. 296:2002;1118-1120.
-
(2002)
Science
, vol.296
, pp. 1118-1120
-
-
Rulifson, E.J.1
Kim, S.K.2
Nusse, R.3
-
2
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M., Bartke A., Antebi A. The endocrine regulation of aging by insulin-like signals. Science. 299:2003;1346-1351.
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
3
-
-
0033664539
-
Insulin receptors and insulin action in the brain: Review and clinical implications
-
Schulingkamp R., Pagano T., Hung D., Raffa R. Insulin receptors and insulin action in the brain: review and clinical implications. Neurosci Biobehav Rev. 24:2000;855-872.
-
(2000)
Neurosci Biobehav Rev
, vol.24
, pp. 855-872
-
-
Schulingkamp, R.1
Pagano, T.2
Hung, D.3
Raffa, R.4
-
5
-
-
0030664286
-
Transport of insulin across the blood-brain barrier: Saturability at euglycemic doses of insulin
-
Banks W.A., Jaspan J.B., Huang W., Kastin A.J. Transport of insulin across the blood-brain barrier: saturability at euglycemic doses of insulin. Peptides. 18:1997;1423-1429.
-
(1997)
Peptides
, vol.18
, pp. 1423-1429
-
-
Banks, W.A.1
Jaspan, J.B.2
Huang, W.3
Kastin, A.J.4
-
6
-
-
0031456345
-
Selective, physiological transport of insulin across the blood-brain barrier: Novel demonstration by species-specific radioimmunoassays
-
Banks W.A., Jaspan J.B., Kastin A.J. Selective, physiological transport of insulin across the blood-brain barrier: novel demonstration by species-specific radioimmunoassays. Peptides. 18:1997;1257-1262.
-
(1997)
Peptides
, vol.18
, pp. 1257-1262
-
-
Banks, W.A.1
Jaspan, J.B.2
Kastin, A.J.3
-
7
-
-
0027361094
-
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo: A mechanism for regulated insulin delivery to the brain
-
Baura G.D., Foster D.M., Porte D. Jr, et al. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo: a mechanism for regulated insulin delivery to the brain. J Clin Invest. 92:1993;1824-1830.
-
(1993)
J Clin Invest
, vol.92
, pp. 1824-1830
-
-
Baura, G.D.1
Foster, D.M.2
Porte Jr., D.3
-
8
-
-
0023161139
-
Insulin in the brain
-
Baskin D., Figlewicz D., Woods S., Porte D., Dorsa D. Insulin in the brain. Annu Rev Physiol. 49:1987;335-347.
-
(1987)
Annu Rev Physiol
, vol.49
, pp. 335-347
-
-
Baskin, D.1
Figlewicz, D.2
Woods, S.3
Porte, D.4
Dorsa, D.5
-
9
-
-
0023153353
-
Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man
-
Wallum B.J., Taborsky G.J., Porte D., et al. Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man. J Clin Endocrinol Metab. 64:1987;190-194.
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 190-194
-
-
Wallum, B.J.1
Taborsky, G.J.2
Porte, D.3
-
10
-
-
0033197996
-
The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses
-
Abbott M., Wells D., Fallon J. The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses. J Neurosci. 19:1999;7300-7308.
-
(1999)
J Neurosci
, vol.19
, pp. 7300-7308
-
-
Abbott, M.1
Wells, D.2
Fallon, J.3
-
12
-
-
0018090354
-
Insulin receptors are widely distributed in the central nervous system of the rat
-
Havrankova J., Roth J., Brownstein M. Insulin receptors are widely distributed in the central nervous system of the rat. Nature. 272:1978;827-829.
-
(1978)
Nature
, vol.272
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
Brownstein, M.3
-
13
-
-
0025847968
-
Insulin receptors in the central nervous system: Localization, signalling mechanisms and functional aspects
-
Unger J.W., Livingston J.N., Moss A.M. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol. 36:1991;343-362.
-
(1991)
Prog Neurobiol
, vol.36
, pp. 343-362
-
-
Unger, J.W.1
Livingston, J.N.2
Moss, A.M.3
-
14
-
-
0032497504
-
Parkinson's disease: First of two parts
-
Lang A.E., Lozano A.M. Parkinson's disease: first of two parts. N Engl J Med. 339:1998;1044-1053.
-
(1998)
N Engl J Med
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
15
-
-
0028310417
-
Insulin gene expression and insulin synthesis in mammalian neuronal cells
-
Devaskar S.U., Giddings S.J., Rajakumar P.A., Carnaghi L.R., Menon R.K., Zahm D.S. Insulin gene expression and insulin synthesis in mammalian neuronal cells. J Biol Chem. 269:1994;8445-8454.
-
(1994)
J Biol Chem
, vol.269
, pp. 8445-8454
-
-
Devaskar, S.U.1
Giddings, S.J.2
Rajakumar, P.A.3
Carnaghi, L.R.4
Menon, R.K.5
Zahm, D.S.6
-
16
-
-
0023778457
-
Insulin synthesis by isolated rabbit neurons
-
Schechter R., Holtzclaw L., Sadiq F., Kahn A., Devaskar S. Insulin synthesis by isolated rabbit neurons. Endocrinology. 23:1988;505-513.
-
(1988)
Endocrinology
, vol.23
, pp. 505-513
-
-
Schechter, R.1
Holtzclaw, L.2
Sadiq, F.3
Kahn, A.4
Devaskar, S.5
-
17
-
-
0030965751
-
Insulin gene expression in immortalized rat hippocampal and pheochromocytoma-12 cell lines
-
Singh B.S., Rajakumar P.A., Eves E.M., Rosner M.R., Wainer B.H., Devaskar S.U. Insulin gene expression in immortalized rat hippocampal and pheochromocytoma-12 cell lines. Regul Pept. 69:1997;7-14.
-
(1997)
Regul Pept
, vol.69
, pp. 7-14
-
-
Singh, B.S.1
Rajakumar, P.A.2
Eves, E.M.3
Rosner, M.R.4
Wainer, B.H.5
Devaskar, S.U.6
-
18
-
-
0034012731
-
Intracerebroventricular insulin enhances memory in a passive-avoidance task
-
Park C.R., Seeley R.J., Craft S., Woods S.C. Intracerebroventricular insulin enhances memory in a passive-avoidance task. Physiol Behav. 68:2000;509-514.
-
(2000)
Physiol Behav
, vol.68
, pp. 509-514
-
-
Park, C.R.1
Seeley, R.J.2
Craft, S.3
Woods, S.C.4
-
19
-
-
0032737079
-
Enhancement of memory in Alzheimer's disease with insulin and somatostatin, but not glucose
-
Craft S., Asthana S., Newcomer J.W., et al. Enhancement of memory in Alzheimer's disease with insulin and somatostatin, but not glucose. Arch Gen Psychiatry. 56:1999;1135-1140.
-
(1999)
Arch Gen Psychiatry
, vol.56
, pp. 1135-1140
-
-
Craft, S.1
Asthana, S.2
Newcomer, J.W.3
-
20
-
-
0034730443
-
Manipulating neuropeptidergic pathways in humans: A novel approach to neuropharmacology?
-
Fehm H.L., Perras B., Smolnik R., Kern W., Born J. Manipulating neuropeptidergic pathways in humans: a novel approach to neuropharmacology? Eur J Pharmacol. 405:2000;43-54.
-
(2000)
Eur J Pharmacol
, vol.405
, pp. 43-54
-
-
Fehm, H.L.1
Perras, B.2
Smolnik, R.3
Kern, W.4
Born, J.5
-
21
-
-
0033521130
-
Brain insulin receptors and spatial memory: Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of the water maze trained rats
-
Zhao W., Chen H., Xu H., et al. Brain insulin receptors and spatial memory: correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of the water maze trained rats. J Biol Chem. 274:1999;34893-34902.
-
(1999)
J Biol Chem
, vol.274
, pp. 34893-34902
-
-
Zhao, W.1
Chen, H.2
Xu, H.3
-
22
-
-
0035706134
-
Glucose treatment reduces memory deficits in young rats fed high-fat diets
-
Greenwood C., Winocur G. Glucose treatment reduces memory deficits in young rats fed high-fat diets. Neurobiol Learn Mem. 75:2001;179-189.
-
(2001)
Neurobiol Learn Mem
, vol.75
, pp. 179-189
-
-
Greenwood, C.1
Winocur, G.2
-
23
-
-
0029064320
-
Altered conditioned taste aversion and glucose utilization in related brain nuclei of diabetic GK rats
-
Marfaing-Jallat P., Portha B., Penicaud L. Altered conditioned taste aversion and glucose utilization in related brain nuclei of diabetic GK rats. Brain Res Bull. 37:1995;639-643.
-
(1995)
Brain Res Bull
, vol.37
, pp. 639-643
-
-
Marfaing-Jallat, P.1
Portha, B.2
Penicaud, L.3
-
24
-
-
0030873815
-
NIDDM and blood pressure as risk factors for poor cognitive performance: The Framingham Study
-
Elias P.K., Elias M.F., D'Agostino R.B., et al. NIDDM and blood pressure as risk factors for poor cognitive performance: the Framingham Study. Diabetes Care. 20:1997;1388-1395.
-
(1997)
Diabetes Care
, vol.20
, pp. 1388-1395
-
-
Elias, P.K.1
Elias, M.F.2
D'Agostino, R.B.3
-
25
-
-
0029040180
-
Short-term and long-term memory in elderly patients with NIDDM
-
Helkala E-L, Niskanen L., Viinamaki H., Partanen J., Uusitupa M. Short-term and long-term memory in elderly patients with NIDDM. Diabetes Care. 18:1995;681-685.
-
(1995)
Diabetes Care
, vol.18
, pp. 681-685
-
-
Helkala, E.-L.1
Niskanen, L.2
Viinamaki, H.3
Partanen, J.4
Uusitupa, M.5
-
26
-
-
0021682933
-
Decreased cognitive function in aging non-insulin-dependent diabetic patients
-
Perlmuter L.C., Hakami M.K., Hodgson-Harrington C., et al. Decreased cognitive function in aging non-insulin-dependent diabetic patients. Am J Med. 77:1984;1043-1048.
-
(1984)
Am J Med
, vol.77
, pp. 1043-1048
-
-
Perlmuter, L.C.1
Hakami, M.K.2
Hodgson-Harrington, C.3
-
27
-
-
0031025854
-
Is type II diabetes associated with an increased risk of cognitive dysfunction? a critical review of published studies
-
Strachan M.W., Deary I.J., Ewing F.M., Frier B.M. Is type II diabetes associated with an increased risk of cognitive dysfunction? A critical review of published studies. Diabetes Care. 20:1997;438-445.
-
(1997)
Diabetes Care
, vol.20
, pp. 438-445
-
-
Strachan, M.W.1
Deary, I.J.2
Ewing, F.M.3
Frier, B.M.4
-
28
-
-
0032769625
-
Type-2 diabetes and cognitive function in a non-demented population
-
Vanhanen M., Kuusisto J., Koivisto K., et al. Type-2 diabetes and cognitive function in a non-demented population. Acta Neurol Scand. 100:1999;97-101.
-
(1999)
Acta Neurol Scand
, vol.100
, pp. 97-101
-
-
Vanhanen, M.1
Kuusisto, J.2
Koivisto, K.3
-
29
-
-
0031888289
-
Cognitive function in an elderly population with persistent impaired glucose tolerance
-
Vanhanen M., Koivisto K., Kuusisto J., et al. Cognitive function in an elderly population with persistent impaired glucose tolerance. Diabetes Care. 21:1998;398-402.
-
(1998)
Diabetes Care
, vol.21
, pp. 398-402
-
-
Vanhanen, M.1
Koivisto, K.2
Kuusisto, J.3
-
30
-
-
0029018829
-
Four-day hyperinsulinemia in euglycemic conditions alters local cerebral glucose utilization in specific brain nuclei of freely moving rats
-
Doyle P., Cusin I., Rohner-Jeanrenaud F., Jeanrenaud B. Four-day hyperinsulinemia in euglycemic conditions alters local cerebral glucose utilization in specific brain nuclei of freely moving rats. Brain Res. 684:1995;47-55.
-
(1995)
Brain Res
, vol.684
, pp. 47-55
-
-
Doyle, P.1
Cusin, I.2
Rohner-Jeanrenaud, F.3
Jeanrenaud, B.4
-
31
-
-
0023260209
-
Effects of insulin on local cerebral glucose utilization in the rat
-
Lucignani G., Namba H., Nehlig A., Porrino L., Kennedy C., Sokoloff L. Effects of insulin on local cerebral glucose utilization in the rat. J Cereb Blood Flow Metab. 7:1987;309-314.
-
(1987)
J Cereb Blood Flow Metab
, vol.7
, pp. 309-314
-
-
Lucignani, G.1
Namba, H.2
Nehlig, A.3
Porrino, L.4
Kennedy, C.5
Sokoloff, L.6
-
32
-
-
0025301069
-
Effects of hyperinsulinemia on local cerebral insulin binding and glucose utilization in normoglycemic awake rats
-
Marfaing P., Penicaud L., Broer Y., Mraovitch S., Calando Y., Picon L. Effects of hyperinsulinemia on local cerebral insulin binding and glucose utilization in normoglycemic awake rats. Neurosci Lett. 115:1990;279-285.
-
(1990)
Neurosci Lett
, vol.115
, pp. 279-285
-
-
Marfaing, P.1
Penicaud, L.2
Broer, Y.3
Mraovitch, S.4
Calando, Y.5
Picon, L.6
-
33
-
-
0031658958
-
Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes
-
Fanelli C., Dence C., Markham J., et al. Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes. Diabetes. 47:1998;1444-1450.
-
(1998)
Diabetes
, vol.47
, pp. 1444-1450
-
-
Fanelli, C.1
Dence, C.2
Markham, J.3
-
34
-
-
0032883250
-
No effect of insulin on glucose blood-brain barrier transport and cerebral metabolism in humans
-
Hasselbalch S., Knudsen G., Videback C., et al. No effect of insulin on glucose blood-brain barrier transport and cerebral metabolism in humans. Diabetes. 48:1999;1915-1921.
-
(1999)
Diabetes
, vol.48
, pp. 1915-1921
-
-
Hasselbalch, S.1
Knudsen, G.2
Videback, C.3
-
35
-
-
0036895563
-
The role of insulin in human brain glucose metabolism: An 18-fluoro-deoxyglucose positron emission tomography study
-
Bingham E.M., Hopkins D., Smith D., et al. The role of insulin in human brain glucose metabolism: an 18-fluoro-deoxyglucose positron emission tomography study. Diabetes. 51:2002;3384-3390.
-
(2002)
Diabetes
, vol.51
, pp. 3384-3390
-
-
Bingham, E.M.1
Hopkins, D.2
Smith, D.3
-
36
-
-
0033199378
-
Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuron-specific localization in rat brain
-
Apelt J., Mehlhorn G., Schliebs R. Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuron-specific localization in rat brain. J Neurosci Res. 57:1999;693-705.
-
(1999)
J Neurosci Res
, vol.57
, pp. 693-705
-
-
Apelt, J.1
Mehlhorn, G.2
Schliebs, R.3
-
37
-
-
0027321678
-
Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system
-
Brant A., Jess T., Milligan G., Brown C., Gould G. Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system. Biochem Biophys Res Commun. 192:1993;1297-1302.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 1297-1302
-
-
Brant, A.1
Jess, T.2
Milligan, G.3
Brown, C.4
Gould, G.5
-
38
-
-
0032487335
-
Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system
-
El-Messari S., Leloup C., Quignon M., Brisorgueil M.J., Penicaud L., Arluison M. Immunocytochemical localization of the insulin-responsive glucose transporter 4 (Glut4) in the rat central nervous system. J Comp Neurol. 399:1998;492-512.
-
(1998)
J Comp Neurol
, vol.399
, pp. 492-512
-
-
El-Messari, S.1
Leloup, C.2
Quignon, M.3
Brisorgueil, M.J.4
Penicaud, L.5
Arluison, M.6
-
39
-
-
0028890116
-
Hypothalamic GLUT 4 expression: A glucose- and insulin-sensing mechanism?
-
Livingstone C., Lyall H., Gould G. Hypothalamic GLUT 4 expression: a glucose- and insulin-sensing mechanism? Mol Cell Endocrinol. 107:1995;67-70.
-
(1995)
Mol Cell Endocrinol
, vol.107
, pp. 67-70
-
-
Livingstone, C.1
Lyall, H.2
Gould, G.3
-
40
-
-
0034681328
-
GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues
-
Ibberson M., Uldry M., Thorens B. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J Biol Chem. 275:2000;4607-4612.
-
(2000)
J Biol Chem
, vol.275
, pp. 4607-4612
-
-
Ibberson, M.1
Uldry, M.2
Thorens, B.3
-
41
-
-
0035956883
-
Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats
-
Reagan L., Gorovits N., Hoskin E., et al. Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats. Proc Natl Acad Sci USA. 98:2001;2820-2825.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2820-2825
-
-
Reagan, L.1
Gorovits, N.2
Hoskin, E.3
-
42
-
-
0035947044
-
Role of insulin and insulin receptor in learning and memory
-
Zhao W-T, Alkon D.L. Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol. 177:2001;125-134.
-
(2001)
Mol Cell Endocrinol
, vol.177
, pp. 125-134
-
-
Zhao, W.-T.1
Alkon, D.L.2
-
43
-
-
0035853124
-
Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis
-
Skeberdis V., Lan J-y, Zheng X., Zuklin R., Bennett M. Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis. Proc Natl Acad Sci USA. 98:2001;3561-3566.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3561-3566
-
-
Skeberdis, V.1
Lan, J.-Y.2
Zheng, X.3
Zuklin, R.4
Bennett, M.5
-
44
-
-
0032863618
-
Effects of posttraining administration of insulin on retention of a habituation response in mice: Participation of a central cholinergic mechanism
-
Kopf S., Baratti C. Effects of posttraining administration of insulin on retention of a habituation response in mice: participation of a central cholinergic mechanism. Neurobiol Learn Mem. 71:1999;50-61.
-
(1999)
Neurobiol Learn Mem
, vol.71
, pp. 50-61
-
-
Kopf, S.1
Baratti, C.2
-
45
-
-
0027400795
-
Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus
-
Figlewicz D.P., Szot P., Israel P.A., Payne C., Dorsa D.M. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus. Brain Res. 602:1993;161-164.
-
(1993)
Brain Res
, vol.602
, pp. 161-164
-
-
Figlewicz, D.P.1
Szot, P.2
Israel, P.A.3
Payne, C.4
Dorsa, D.M.5
-
46
-
-
0030053556
-
Memory improvement following induced hyperinsulinemia in Alzheimer's disease
-
Craft S., Newcomer J., Kanne S., et al. Memory improvement following induced hyperinsulinemia in Alzheimer's disease. Neurobiol Aging. 17:1996;123-130.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 123-130
-
-
Craft, S.1
Newcomer, J.2
Kanne, S.3
-
47
-
-
12944268985
-
Clinical criteria for the diagnosis of vascular dementia: A multicenter study of comparability and interrater reliability
-
Chui H., Mack W., Jackson J., et al. Clinical criteria for the diagnosis of vascular dementia: a multicenter study of comparability and interrater reliability. Arch Neurol. 57:2000;191-196.
-
(2000)
Arch Neurol
, vol.57
, pp. 191-196
-
-
Chui, H.1
MacK, W.2
Jackson, J.3
-
48
-
-
0034603512
-
The role of cerebral ischemia in Alzheimer's disease
-
Kalaria R.N. The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging. 21:2000;321-330.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 321-330
-
-
Kalaria, R.N.1
-
49
-
-
0031897103
-
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults: The Third National Health and Nutrition Examination Survey, 1988-1994
-
Harris M.I., Flegal K.M., Cowie C.C., et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults: The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care. 21:1998;518-524.
-
(1998)
Diabetes Care
, vol.21
, pp. 518-524
-
-
Harris, M.I.1
Flegal, K.M.2
Cowie, C.C.3
-
50
-
-
0034707612
-
Is diabetes associated with cognitive impairment and cognitive decline among older women?
-
Gregg E.W., Yaffe K., Cauley J.A., et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Arch Intern Med. 160:2000;174-180.
-
(2000)
Arch Intern Med
, vol.160
, pp. 174-180
-
-
Gregg, E.W.1
Yaffe, K.2
Cauley, J.A.3
-
51
-
-
0029966901
-
Association of diabetes mellitus and dementia: The Rotterdam Study
-
Ott A., Stolk R.P., Hofman A., van Harskamp F., Grobbee D.E., Breteler M.M. Association of diabetes mellitus and dementia: the Rotterdam Study. Diabetologia. 39:1996;1392-1397.
-
(1996)
Diabetologia
, vol.39
, pp. 1392-1397
-
-
Ott, A.1
Stolk, R.P.2
Hofman, A.3
Van Harskamp, F.4
Grobbee, D.E.5
Breteler, M.M.6
-
52
-
-
0031050268
-
Risk of dementia among persons with diabetes mellitus: A population-based cohort study
-
Leibson C.L., Rocca W.A., Hanson V.A., et al. Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am J Epidemiol. 145:1997;301-308.
-
(1997)
Am J Epidemiol
, vol.145
, pp. 301-308
-
-
Leibson, C.L.1
Rocca, W.A.2
Hanson, V.A.3
-
53
-
-
0031918631
-
Vascular risks and incident dementia: Results from a cohort study of the very old
-
Brayne C., Gill C., Huppert F. Vascular risks and incident dementia: results from a cohort study of the very old. Dement Geriatr Cogn Disord. 9:1998;175-180.
-
(1998)
Dement Geriatr Cogn Disord
, vol.9
, pp. 175-180
-
-
Brayne, C.1
Gill, C.2
Huppert, F.3
-
54
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A., Stolk R.P., van Harskamp F., Pols H.A., Hofman A., Breteler M.M. Diabetes mellitus and the risk of dementia: the Rotterdam Study. Neurology. 10:1999;1937-1942.
-
(1999)
Neurology
, vol.10
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
Van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
56
-
-
0033596837
-
Longitudinal association of vascular and Alzheimer's dementias, diabetes, and glucose tolerance
-
Curb J.D., Rodriguez B.L., Abbott R.D., et al. Longitudinal association of vascular and Alzheimer's dementias, diabetes, and glucose tolerance. Neurology. 52:1999;971-975.
-
(1999)
Neurology
, vol.52
, pp. 971-975
-
-
Curb, J.D.1
Rodriguez, B.L.2
Abbott, R.D.3
-
57
-
-
0036227542
-
Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
-
Peila R., Rodriguez B.L., Launer L.J. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes. 51:2002;1256-1262.
-
(2002)
Diabetes
, vol.51
, pp. 1256-1262
-
-
Peila, R.1
Rodriguez, B.L.2
Launer, L.J.3
-
58
-
-
9844229370
-
Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study
-
Kuusisto J., Koivisto K., Mykkanen L., et al. Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based study. BMJ. 315:1997;1045-1049.
-
(1997)
BMJ
, vol.315
, pp. 1045-1049
-
-
Kuusisto, J.1
Koivisto, K.2
Mykkanen, L.3
-
59
-
-
1242266796
-
Hyperinsulinemia and risk of Alzheimer's disease
-
Gothenborg, Sweden
-
Luchsinger JA, Tang MX, Shea S, Mayeux R. Hyperinsulinemia and risk of Alzheimer's disease. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). Gothenborg, Sweden, 2003.
-
(2003)
First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003)
-
-
Luchsinger, J.A.1
Tang, M.X.2
Shea, S.3
Mayeux, R.4
-
60
-
-
0035743089
-
Improving influence of insulin on cognitive functions in humans
-
Kern W., Peters A., Fruehwald-Schultes B., Deininger E., Born J., Fehm H. Improving influence of insulin on cognitive functions in humans. Neuroendocrinology. 74:2001;270-280.
-
(2001)
Neuroendocrinology
, vol.74
, pp. 270-280
-
-
Kern, W.1
Peters, A.2
Fruehwald-Schultes, B.3
Deininger, E.4
Born, J.5
Fehm, H.6
-
61
-
-
0032841571
-
Insulin metabolism in Alzheimer's disease differs according to apolipoprotein e genotype and gender
-
Craft S., Asthana S., Schellenberg G.D., et al. Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender. Neuroendocrinology. 70:1999;146-152.
-
(1999)
Neuroendocrinology
, vol.70
, pp. 146-152
-
-
Craft, S.1
Asthana, S.2
Schellenberg, G.D.3
-
62
-
-
0036311771
-
The aging brain: Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD)
-
Hoyer S. The aging brain: changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). J Neural Transm. 109:2002;991-1002.
-
(2002)
J Neural Transm
, vol.109
, pp. 991-1002
-
-
Hoyer, S.1
-
63
-
-
15444339756
-
Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease
-
Frolich L., Blum-Degen D., Bernstein H.G., et al. Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease. J Neural Transm. 105:1998;423-438.
-
(1998)
J Neural Transm
, vol.105
, pp. 423-438
-
-
Frolich, L.1
Blum-Degen, D.2
Bernstein, H.G.3
-
64
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
-
Craft S., Peskind E., Schwartz M.W., Schellenberg G.D., Raskind M., Porte D. Jr. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology. 50:1998;164-168.
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
Schellenberg, G.D.4
Raskind, M.5
Porte Jr., D.6
-
65
-
-
0026332340
-
Increased insulin levels after OGTT load in peripheral blood and cerebrospinal fluid of patients with dementia of Alzheimer type
-
Fujisawa Y., Sasaki K., Akiyama K. Increased insulin levels after OGTT load in peripheral blood and cerebrospinal fluid of patients with dementia of Alzheimer type. Biol Psychiatry. 30:1991;1219-1228.
-
(1991)
Biol Psychiatry
, vol.30
, pp. 1219-1228
-
-
Fujisawa, Y.1
Sasaki, K.2
Akiyama, K.3
-
66
-
-
0035871641
-
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L., Gouras G.K., Wang R., et al. Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci. 21:2001;2561-2570.
-
(2001)
J Neurosci
, vol.21
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
-
68
-
-
0028176821
-
Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
Kurochkin I.V., Goto S. Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett. 345:1994;33-37.
-
(1994)
FEBS Lett
, vol.345
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
69
-
-
0031044352
-
Degradation of Alzheimer's β-amyloid protein by human and rat brain peptidases: Involvement of insulin-degrading enzyme
-
McDermott J.R., Gibson A.M. Degradation of Alzheimer's β-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem Res. 22:1997;49-56.
-
(1997)
Neurochem Res
, vol.22
, pp. 49-56
-
-
McDermott, J.R.1
Gibson, A.M.2
-
70
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid β-protein by degradation
-
Qiu W.Q., Walsh D.M., Ye Z., et al. Insulin-degrading enzyme regulates extracellular levels of amyloid β-protein by degradation. J Biol Chem. 273:1998;32730-32738.
-
(1998)
J Biol Chem
, vol.273
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
-
71
-
-
0037192120
-
Differential effects of proteases involved in intracellular degradation of amyloid β-protein between detergent-soluble and insoluble pools in CHO-695 cells
-
Sudoh S., Frosch M.P., Wolf B.A. Differential effects of proteases involved in intracellular degradation of amyloid β-protein between detergent-soluble and insoluble pools in CHO-695 cells. Biochemistry (Mosc). 41:2002;1091-1099.
-
(2002)
Biochemistry (Mosc)
, vol.41
, pp. 1091-1099
-
-
Sudoh, S.1
Frosch, M.P.2
Wolf, B.A.3
-
72
-
-
0037134505
-
Insulin-degrading enzyme rapidly removes the β-amyloid precursor protein intracellular domain (AICD)
-
Edbauer D., Willem M., Lammich S., Steiner H., Haass C. Insulin-degrading enzyme rapidly removes the β-amyloid precursor protein intracellular domain (AICD). J Biol Chem. 277:2002;279-288.
-
(2002)
J Biol Chem
, vol.277
, pp. 279-288
-
-
Edbauer, D.1
Willem, M.2
Lammich, S.3
Steiner, H.4
Haass, C.5
-
73
-
-
0034038036
-
Degradation of soluble amyloid β-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
-
Perez A., Morelli L., Cresto J.C., Castano E.M. Degradation of soluble amyloid β-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. Neurochem Res. 25:2000;247-255.
-
(2000)
Neurochem Res
, vol.25
, pp. 247-255
-
-
Perez, A.1
Morelli, L.2
Cresto, J.C.3
Castano, E.M.4
-
74
-
-
0037219221
-
Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele
-
Cook D.G., Leverenz J.B., McMillan P.J., et al. Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. Am J Pathol. 162:2003;313-319.
-
(2003)
Am J Pathol
, vol.162
, pp. 313-319
-
-
Cook, D.G.1
Leverenz, J.B.2
McMillan, P.J.3
-
75
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
-
Farris W., Mansourian S., Chang Y., et al. Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci USA. 100:2003;4162-4167.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
-
76
-
-
85030903359
-
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
-
in press
-
Ho L, Qin W, Pompl PL, et al. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J (in press).
-
FASEB J
-
-
Ho, L.1
Qin, W.2
Pompl, P.L.3
-
77
-
-
0038038865
-
Insulin Increases CSF Aβ42 levels in normal older adults
-
Watson G.S., Peskind E.R., Asthana S., et al. Insulin Increases CSF Aβ42 levels in normal older adults. Neurology. 60:2003;1899-1903.
-
(2003)
Neurology
, vol.60
, pp. 1899-1903
-
-
Watson, G.S.1
Peskind, E.R.2
Asthana, S.3
-
78
-
-
0035907325
-
Amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised
-
Tong L., Thornton P.L., Balazs R., Cotman C.W. amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised. J Biol Chem. 276:2001;17301-17306.
-
(2001)
J Biol Chem
, vol.276
, pp. 17301-17306
-
-
Tong, L.1
Thornton, P.L.2
Balazs, R.3
Cotman, C.W.4
-
79
-
-
0036489445
-
The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease
-
Westerman M., Cooper-Blacketer D., Mariash A. The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci. 22:2002;1858-1867.
-
(2002)
J Neurosci
, vol.22
, pp. 1858-1867
-
-
Westerman, M.1
Cooper-Blacketer, D.2
Mariash, A.3
-
80
-
-
0037059598
-
Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
-
Wang H.W., Pasternak J.F., Kuo H., et al. Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus. Brain Res. 924:2002;133-140.
-
(2002)
Brain Res
, vol.924
, pp. 133-140
-
-
Wang, H.W.1
Pasternak, J.F.2
Kuo, H.3
-
81
-
-
0025279593
-
Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats
-
Schwartz M.W., Figlewicz D.F., Kahn S.E., Baskin D.G., Greenwood M.R., Porte D.J. Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats. Peptides. 11:1990;467-472.
-
(1990)
Peptides
, vol.11
, pp. 467-472
-
-
Schwartz, M.W.1
Figlewicz, D.F.2
Kahn, S.E.3
Baskin, D.G.4
Greenwood, M.R.5
Porte, D.J.6
-
82
-
-
0027223525
-
Basal and hyperinsulinemia-induced immunoreactive hypothalamic insulin changes in lean and genetically obese Zucker rats revealed by microdialysis
-
Gerozissis K., Orosco M., Rouch C., Nicolaidis S. Basal and hyperinsulinemia-induced immunoreactive hypothalamic insulin changes in lean and genetically obese Zucker rats revealed by microdialysis. Brain Res. 611:1993;258-263.
-
(1993)
Brain Res
, vol.611
, pp. 258-263
-
-
Gerozissis, K.1
Orosco, M.2
Rouch, C.3
Nicolaidis, S.4
-
83
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
Oddo S., Caccamo A., Shepherd J.D., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron. 39:2003;409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
-
84
-
-
0030748390
-
Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons
-
Hong M., Lee V. Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. J Biol Chem. 272:1997;19547-19553.
-
(1997)
J Biol Chem
, vol.272
, pp. 19547-19553
-
-
Hong, M.1
Lee, V.2
-
85
-
-
0043127453
-
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
-
Schubert M., Brazil D.P., Burks D.J., et al. Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. J Neurosci. 23:2003;7084-7092.
-
(2003)
J Neurosci
, vol.23
, pp. 7084-7092
-
-
Schubert, M.1
Brazil, D.P.2
Burks, D.J.3
-
86
-
-
0035693924
-
Inflamation, autotoxicity and Alzheimer's disease
-
McGeer P.L., McGeer E.G. Inflamation, autotoxicity and Alzheimer's disease. Neurobiol Aging. 22:2001;799-809.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
87
-
-
0036706725
-
Endothelium, inflammation, and diabetes
-
Dandona P. Endothelium, inflammation, and diabetes. Curr Diab Rep. 2:2002;311-315.
-
(2002)
Curr Diab Rep
, vol.2
, pp. 311-315
-
-
Dandona, P.1
-
88
-
-
0034672599
-
Hyperinsulinemia: The missing link among oxidative stress and age-related disease?
-
Facchini F.S., Hua N.W., Reaven G.M., Stoohs R.A. Hyperinsulinemia: the missing link among oxidative stress and age-related disease? Free Radic Biol Med. 29:2000;1302-1306.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 1302-1306
-
-
Facchini, F.S.1
Hua, N.W.2
Reaven, G.M.3
Stoohs, R.A.4
-
89
-
-
0025949417
-
Insulin, prostaglandins, and the pathogenesis of hypertension
-
Axelrod L. Insulin, prostaglandins, and the pathogenesis of hypertension. Diabetes. 40:1991;1223-1227.
-
(1991)
Diabetes
, vol.40
, pp. 1223-1227
-
-
Axelrod, L.1
-
90
-
-
0032588412
-
F2-isoprostane evidence of oxidant stress in the insulin resistant, obese Zucker rat: Effects of vitamin e
-
Laight D., Desai K., Gopul N. F2-isoprostane evidence of oxidant stress in the insulin resistant, obese Zucker rat: effects of vitamin E. Eur J Pharmacol. 377:1999;89-92.
-
(1999)
Eur J Pharmacol
, vol.377
, pp. 89-92
-
-
Laight, D.1
Desai, K.2
Gopul, N.3
-
91
-
-
0036086942
-
Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans
-
Soop M., Duxbury H., Agwunobi A. Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans. Am J Physiol Endocrinol Metab. 282:2002;E1276-1285.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
, pp. 1276-1285
-
-
Soop, M.1
Duxbury, H.2
Agwunobi, A.3
-
92
-
-
0036724836
-
Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease
-
Liolitsa D., Powell J., Lovestone S. Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease. J Neurol Neurosurg Psychiatry. 73:2002;261-266.
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.73
, pp. 261-266
-
-
Liolitsa, D.1
Powell, J.2
Lovestone, S.3
-
93
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram L., Blacker D., Mullin K., et al. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science. 290:2000;2302-2303.
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
-
94
-
-
0037036168
-
Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample
-
Ait-Ghezala G., Abdullah L., Crescentini R., et al. Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample. Neurosci Lett. 325:2002;87-90.
-
(2002)
Neurosci Lett
, vol.325
, pp. 87-90
-
-
Ait-Ghezala, G.1
Abdullah, L.2
Crescentini, R.3
-
95
-
-
0037162647
-
Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease
-
Boussaha M., Hannequin D., Verpillat B., Frebourg T., Campior D. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci Lett. 329:2002;121-123.
-
(2002)
Neurosci Lett
, vol.329
, pp. 121-123
-
-
Boussaha, M.1
Hannequin, D.2
Verpillat, B.3
Frebourg, T.4
Campior, D.5
-
96
-
-
0035687018
-
Substanial linkage disequilibrium across the insulin degrading enzyme locus but no association with late-onset Alzheimer's disease
-
Abraham R., Myers A., Wayrant-DeVrieze F. Substanial linkage disequilibrium across the insulin degrading enzyme locus but no association with late-onset Alzheimer's disease. Hum Genet. 109:2001;646-652.
-
(2001)
Hum Genet
, vol.109
, pp. 646-652
-
-
Abraham, R.1
Myers, A.2
Wayrant-Devrieze, F.3
-
97
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers A., Holmans P., Marshal H., et al. Susceptibility locus for Alzheimer's disease on chromosome 10. Science. 290:2000;2304-2305.
-
(2000)
Science
, vol.290
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshal, H.3
-
98
-
-
0034703979
-
Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N., Graff-Radford N., Younkin L.H., et al. Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science. 290:2000;2303-2304.
-
(2000)
Science
, vol.290
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
-
99
-
-
0038519618
-
Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: Evidence of effect modification by apolipoprotein e (APOE)
-
Edland S.D., Wavrant-De Vriese F., Compton D., et al. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). Neurosci Lett. 345:2003;21-24.
-
(2003)
Neurosci Lett
, vol.345
, pp. 21-24
-
-
Edland, S.D.1
Wavrant-De Vriese, F.2
Compton, D.3
-
100
-
-
0037131385
-
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
-
Pandini G., Frasca F., Mineo R., Sciacca L., Vigneri R., Belfiore A. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. J Biol Chem. 277:2002;39684-39695.
-
(2002)
J Biol Chem
, vol.277
, pp. 39684-39695
-
-
Pandini, G.1
Frasca, F.2
Mineo, R.3
Sciacca, L.4
Vigneri, R.5
Belfiore, A.6
-
101
-
-
0035742583
-
Insulin and insulin-like growth factor I receptors: Similarities and differences in signal transduction
-
Dupont J., LeRoith D. Insulin and insulin-like growth factor I receptors: similarities and differences in signal transduction. Horm Res. 55:(suppl 2):2001;22-26.
-
(2001)
Horm Res
, vol.55
, Issue.SUPPL. 2
, pp. 22-26
-
-
Dupont, J.1
Leroith, D.2
-
102
-
-
0036550234
-
Signalling through IGF-I and insulin receptors: Where is the specificity?
-
Kim J.J., Accili D. Signalling through IGF-I and insulin receptors: where is the specificity? Growth Horm IGF Res. 12:2002;84-90.
-
(2002)
Growth Horm IGF Res
, vol.12
, pp. 84-90
-
-
Kim, J.J.1
Accili, D.2
-
103
-
-
0036917631
-
Serum insulin-like growth factor I regulates brain amyloid-β levels
-
Carro E., Trejo J.L., Gomez-Isla T., LeRoith D., Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-β levels. Nat Med. 8:2002;1390-1397.
-
(2002)
Nat Med
, vol.8
, pp. 1390-1397
-
-
Carro, E.1
Trejo, J.L.2
Gomez-Isla, T.3
Leroith, D.4
Torres-Aleman, I.5
-
104
-
-
0142026832
-
Potential roles of insulin and IGF-1 in Alzheimer's disease
-
Gasparini L., Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci. 26:2003;404-406.
-
(2003)
Trends Neurosci
, vol.26
, pp. 404-406
-
-
Gasparini, L.1
Xu, H.2
-
105
-
-
0025038730
-
Increased transcapillary escape rate of albumin in nondiabetic men in response to hyperinsulinemia
-
Nestler J.E., Barlascini C.O., Tetrault G.A., Fratkin M.J., Clore J.N., Blackard W.G. Increased transcapillary escape rate of albumin in nondiabetic men in response to hyperinsulinemia. Diabetes. 39:1990;1212-1217.
-
(1990)
Diabetes
, vol.39
, pp. 1212-1217
-
-
Nestler, J.E.1
Barlascini, C.O.2
Tetrault, G.A.3
Fratkin, M.J.4
Clore, J.N.5
Blackard, W.G.6
-
106
-
-
0037900056
-
Pathophysiological implications of insulin resistance on vascular endothelial function
-
Wheatcroft S.B., Williams I.L., Shah A.M., Kearney M.T. Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet Med. 20:2003;255-268.
-
(2003)
Diabet Med
, vol.20
, pp. 255-268
-
-
Wheatcroft, S.B.1
Williams, I.L.2
Shah, A.M.3
Kearney, M.T.4
-
107
-
-
0036851743
-
The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome
-
Baird T., Parsons M., Barber P., et al. The influence of diabetes mellitus and hyperglycaemia on stroke incidence and outcome. J Clin Neurosci. 9:2002;618-626.
-
(2002)
J Clin Neurosci
, vol.9
, pp. 618-626
-
-
Baird, T.1
Parsons, M.2
Barber, P.3
-
108
-
-
0037316809
-
Epidemiology of the insulin resistance syndrome
-
Meigs J. Epidemiology of the insulin resistance syndrome. Curr Diab Rep. 3:2003;73-79.
-
(2003)
Curr Diab Rep
, vol.3
, pp. 73-79
-
-
Meigs, J.1
-
109
-
-
0027435481
-
Essential hypertension and cognitive function: The role of hyperinsulinaemia
-
Kuusisto J., Koivisto K., Mykkanen L., et al. Essential hypertension and cognitive function: the role of hyperinsulinaemia. Hypertension. 22:1993;771-779.
-
(1993)
Hypertension
, vol.22
, pp. 771-779
-
-
Kuusisto, J.1
Koivisto, K.2
Mykkanen, L.3
-
110
-
-
0024270344
-
Aetiological considerations and risk factors for multi-infarct dementia
-
Meyer J.S., McClintic K.L., Rogers R.L., Sims P., Mortel K.F. Aetiological considerations and risk factors for multi-infarct dementia. J Neurol Neurosurg Psychiatry. 51:1988;1489-1497.
-
(1988)
J Neurol Neurosurg Psychiatry
, vol.51
, pp. 1489-1497
-
-
Meyer, J.S.1
McClintic, K.L.2
Rogers, R.L.3
Sims, P.4
Mortel, K.F.5
-
111
-
-
0033595203
-
Characterization of risk factors for vascular dementia: The Honolulu-Asia Aging Study
-
Ross G.W., Petrovitch H., White L.R., et al. Characterization of risk factors for vascular dementia: the Honolulu-Asia Aging Study. Neurology. 53:1999;337-343.
-
(1999)
Neurology
, vol.53
, pp. 337-343
-
-
Ross, G.W.1
Petrovitch, H.2
White, L.R.3
-
112
-
-
0037318833
-
Prevalence of dementia in older latinos: The influence of type 2 diabetes mellitus, stroke and genetic factors
-
Haan M.N., Mungas D.M., Gonzalez H.M., Ortiz T.A., Acharya A., Jagust W.J. Prevalence of dementia in older latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors. J Am Geriatr Soc. 51:2003;169-177.
-
(2003)
J Am Geriatr Soc
, vol.51
, pp. 169-177
-
-
Haan, M.N.1
Mungas, D.M.2
Gonzalez, H.M.3
Ortiz, T.A.4
Acharya, A.5
Jagust, W.J.6
-
113
-
-
0033999608
-
Alzheimer disease and vascular dementia: Relationships with fasting glucose and insulin levels
-
Carantoni M., Zuliani G., Munari M.R., D'Elia K., Palmieri E., Fellin R. Alzheimer disease and vascular dementia: relationships with fasting glucose and insulin levels. Dement Geriatr Cogn Disord. 11:2000;176-180.
-
(2000)
Dement Geriatr Cogn Disord
, vol.11
, pp. 176-180
-
-
Carantoni, M.1
Zuliani, G.2
Munari, M.R.3
D'Elia, K.4
Palmieri, E.5
Fellin, R.6
-
114
-
-
0036759508
-
Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest old
-
Hassing L.B., Johansson B., Nilsson S.E., et al. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr. 14:2002;239-248.
-
(2002)
Int Psychogeriatr
, vol.14
, pp. 239-248
-
-
Hassing, L.B.1
Johansson, B.2
Nilsson, S.E.3
-
115
-
-
0037167548
-
Insulin resistance and risk for stroke
-
Kernan W., Inzucchi S., Viscoli C., Brass L., Bravata D., Horwitz R. Insulin resistance and risk for stroke. Neurology. 59:2002;809-815.
-
(2002)
Neurology
, vol.59
, pp. 809-815
-
-
Kernan, W.1
Inzucchi, S.2
Viscoli, C.3
Brass, L.4
Bravata, D.5
Horwitz, R.6
-
116
-
-
0027561888
-
The relationship between diabetes mellitus and Parkinson's disease
-
Sandyk R. The relationship between diabetes mellitus and Parkinson's disease. Int J Neurosci. 69:1993;125-130.
-
(1993)
Int J Neurosci
, vol.69
, pp. 125-130
-
-
Sandyk, R.1
-
117
-
-
0037435524
-
The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism
-
Pressley J.C., Louis E.D., Tang M.X., et al. The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism. Neurology. 60:2003;87-93.
-
(2003)
Neurology
, vol.60
, pp. 87-93
-
-
Pressley, J.C.1
Louis, E.D.2
Tang, M.X.3
-
118
-
-
0015029469
-
Glucose, insulin, and free fatty acid metabolism in Parkinson's disease treated with levodopa
-
Van Woert M.H., Mueller P.S. Glucose, insulin, and free fatty acid metabolism in Parkinson's disease treated with levodopa. Clin Pharmacol Ther. 12:1971;360-367.
-
(1971)
Clin Pharmacol Ther
, vol.12
, pp. 360-367
-
-
Van Woert, M.H.1
Mueller, P.S.2
-
119
-
-
0015504340
-
Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism
-
Sirtori C.R., Bolme P., Azarnoff D.L. Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism. N Engl J Med. 287:1972;729-733.
-
(1972)
N Engl J Med
, vol.287
, pp. 729-733
-
-
Sirtori, C.R.1
Bolme, P.2
Azarnoff, D.L.3
-
120
-
-
0015145828
-
Endocrine function and glucose metabolism in patients with Parkinson's disease and their alternation by L-Dopa
-
Boyd AE III, Lebovitz H.E., Feldman J.M. Endocrine function and glucose metabolism in patients with Parkinson's disease and their alternation by L-Dopa. J Clin Endocrinol Metab. 33:1971;829-837.
-
(1971)
J Clin Endocrinol Metab
, vol.33
, pp. 829-837
-
-
Boyd III, A.E.1
Lebovitz, H.E.2
Feldman, J.M.3
-
122
-
-
0034776121
-
Vascular parkinsonism: A distinct, heterogeneous clinical entity
-
Demirkiran M., Bozdemir H., Sarica Y. Vascular parkinsonism: a distinct, heterogeneous clinical entity. Acta Neurol Scand. 104:2001;63-67.
-
(2001)
Acta Neurol Scand
, vol.104
, pp. 63-67
-
-
Demirkiran, M.1
Bozdemir, H.2
Sarica, Y.3
-
123
-
-
0036138209
-
Vascular parkinsonism: A review of the precision and frequency of the diagnosis
-
Foltynie T., Barker R., Brayne C. Vascular parkinsonism: a review of the precision and frequency of the diagnosis. Neuroepidemiology. 21:2002;1-7.
-
(2002)
Neuroepidemiology
, vol.21
, pp. 1-7
-
-
Foltynie, T.1
Barker, R.2
Brayne, C.3
-
124
-
-
0038798102
-
Prevalence of cerebrovascular lesions in Parkinson's disease: A postmortem study
-
Jellinger K.A. Prevalence of cerebrovascular lesions in Parkinson's disease: a postmortem study. Acta Neuropathol (Berl). 105:2003;415-419.
-
(2003)
Acta Neuropathol (Berl)
, vol.105
, pp. 415-419
-
-
Jellinger, K.A.1
-
125
-
-
0039267710
-
Progession and prognosis in Parkinson's disease
-
Schwab R.S. Progession and prognosis in Parkinson's disease. J Nerv Ment Dis. 130:1960;556-566.
-
(1960)
J Nerv Ment Dis
, vol.130
, pp. 556-566
-
-
Schwab, R.S.1
-
126
-
-
0026854957
-
The association of diabetes mellitus with dementia in Parkinson's disease
-
Sandyk R., Awerbuch G.I. The association of diabetes mellitus with dementia in Parkinson's disease. Int J Neurosci. 64:1992;209-212.
-
(1992)
Int J Neurosci
, vol.64
, pp. 209-212
-
-
Sandyk, R.1
Awerbuch, G.I.2
-
127
-
-
0025167871
-
Risk factors for dementia in Parkinson's disease
-
Salgnik I., Korczyn A. Risk factors for dementia in Parkinson's disease. Adv Neurol. 53:1990;343-347.
-
(1990)
Adv Neurol
, vol.53
, pp. 343-347
-
-
Salgnik, I.1
Korczyn, A.2
-
128
-
-
0036523773
-
Do risk factors for Alzheimer's disease predict dementia in Parkinson's disease? An exploratory study
-
Levy G., Tang M.X., Cote L.J., et al. Do risk factors for Alzheimer's disease predict dementia in Parkinson's disease? An exploratory study. Mov Disord. 17:2002;250-257.
-
(2002)
Mov Disord
, vol.17
, pp. 250-257
-
-
Levy, G.1
Tang, M.X.2
Cote, L.J.3
-
129
-
-
0028344810
-
Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease
-
Moroo I., Yamada T., Makino H., et al. Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease. Acta Neuropathol (Berl). 87:1994;343-348.
-
(1994)
Acta Neuropathol (Berl)
, vol.87
, pp. 343-348
-
-
Moroo, I.1
Yamada, T.2
Makino, H.3
-
130
-
-
0030047594
-
Insulin receptor mRNA in the substantia nigra in Parkinson's disease
-
Takahashi M., Yamada T., Tooyama I., et al. Insulin receptor mRNA in the substantia nigra in Parkinson's disease. Neurosci Lett. 204:1996;201-204.
-
(1996)
Neurosci Lett
, vol.204
, pp. 201-204
-
-
Takahashi, M.1
Yamada, T.2
Tooyama, I.3
-
131
-
-
0034108740
-
Normal cerebrospinal fluid levels of insulin in patients with Parkinson's disease
-
Jimenez-Jimenez F.J., Molina J.A., Vargas C., et al. Normal cerebrospinal fluid levels of insulin in patients with Parkinson's disease. J Neural Transm. 107:2000;445-449.
-
(2000)
J Neural Transm
, vol.107
, pp. 445-449
-
-
Jimenez-Jimenez, F.J.1
Molina, J.A.2
Vargas, C.3
-
132
-
-
0033048184
-
Intracerebroventricular administration of bromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters
-
Luo S., Liang Y., Cincotta A.H. Intracerebroventricular administration of bromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters. Neuroendocrinology. 69:1999;160-166.
-
(1999)
Neuroendocrinology
, vol.69
, pp. 160-166
-
-
Luo, S.1
Liang, Y.2
Cincotta, A.H.3
-
133
-
-
0028230437
-
Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra
-
Figlewicz D.P., Szot P., Chavez M., Woods S.C., Veith R.C. Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra. Brain Res. 644:1994;331-334.
-
(1994)
Brain Res
, vol.644
, pp. 331-334
-
-
Figlewicz, D.P.1
Szot, P.2
Chavez, M.3
Woods, S.C.4
Veith, R.C.5
-
134
-
-
0034869027
-
Peptide derived from insulin with regulatory activity of dopamine transporter
-
Liu Z., Wang Y., Zhao W., et al. Peptide derived from insulin with regulatory activity of dopamine transporter. Neuropharmacology. 41:2001;464-471.
-
(2001)
Neuropharmacology
, vol.41
, pp. 464-471
-
-
Liu, Z.1
Wang, Y.2
Zhao, W.3
-
135
-
-
0030583628
-
Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: A molecular study
-
Figlewicz D.P., Brot M.D., McCall A.L., Szot P. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Res. 736:1996;54-60.
-
(1996)
Brain Res
, vol.736
, pp. 54-60
-
-
Figlewicz, D.P.1
Brot, M.D.2
McCall, A.L.3
Szot, P.4
-
136
-
-
0030052817
-
Diabetes decreases limbic extracellular dopamine in rats
-
Murzi E., Contreras Q., Teneud L., et al. Diabetes decreases limbic extracellular dopamine in rats. Neurosci Lett. 202:1996;141-144.
-
(1996)
Neurosci Lett
, vol.202
, pp. 141-144
-
-
Murzi, E.1
Contreras, Q.2
Teneud, L.3
-
137
-
-
0019865177
-
Dopamine receptor binding is increased in diabetic rats
-
Lozovsky D., Saller C.F., Kopin I.J. Dopamine receptor binding is increased in diabetic rats. Science. 214:1981;1031-1033.
-
(1981)
Science
, vol.214
, pp. 1031-1033
-
-
Lozovsky, D.1
Saller, C.F.2
Kopin, I.J.3
-
138
-
-
0017369458
-
Abnormal glucose tolerance and arginine tolerance tests in Huntington's disease
-
Podolsky S., Leopold N.A. Abnormal glucose tolerance and arginine tolerance tests in Huntington's disease. Gerontology. 23:1977;55-63.
-
(1977)
Gerontology
, vol.23
, pp. 55-63
-
-
Podolsky, S.1
Leopold, N.A.2
-
139
-
-
0021927818
-
Diabetes mellitus in Huntington disease
-
Farrer L.A. Diabetes mellitus in Huntington disease. Clin Genet. 27:1985;62-67.
-
(1985)
Clin Genet
, vol.27
, pp. 62-67
-
-
Farrer, L.A.1
-
140
-
-
0017127204
-
Fatty acid patterns and glucose tolerance in Huntington's chorea
-
Schobotz R., Hausmann L., Kaffarnik H., Zehner J., Oepen H. Fatty acid patterns and glucose tolerance in Huntington's chorea. Res Exp Med (Berl). 167:1976;203-215.
-
(1976)
Res Exp Med (Berl)
, vol.167
, pp. 203-215
-
-
Schobotz, R.1
Hausmann, L.2
Kaffarnik, H.3
Zehner, J.4
Oepen, H.5
-
141
-
-
0033009587
-
Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes
-
Hurlbert M.S., Zhou W., Wasmeier C., Kaddis F.G., Hutton J.C., Freed C.R. Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes. Diabetes. 48:1999;649-651.
-
(1999)
Diabetes
, vol.48
, pp. 649-651
-
-
Hurlbert, M.S.1
Zhou, W.2
Wasmeier, C.3
Kaddis, F.G.4
Hutton, J.C.5
Freed, C.R.6
-
142
-
-
0037002444
-
Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression
-
Andreassen O.A., Dedeoglu A., Stanojevic V., et al. Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression. Neurobiol Dis. 11:2002;410-424.
-
(2002)
Neurobiol Dis
, vol.11
, pp. 410-424
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Stanojevic, V.3
-
143
-
-
0035979811
-
Insulin receptor substrate protein p53 localization in rats suggests mechanism for specific polyglutamine neurodegeneration
-
Thomas E., Foye P., Alvarez C., Usui H., Stucliffe J. Insulin receptor substrate protein p53 localization in rats suggests mechanism for specific polyglutamine neurodegeneration. Neurosci Lett. 309:2001;145-148.
-
(2001)
Neurosci Lett
, vol.309
, pp. 145-148
-
-
Thomas, E.1
Foye, P.2
Alvarez, C.3
Usui, H.4
Stucliffe, J.5
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