-
2
-
-
36348934620
-
Aspects of beta-amyloid as a biomarker for Alzheimers disease
-
Andreasson U, Portelius E, Andersson ME, Blennow K, Zetterberg H. Aspects of beta-amyloid as a biomarker for Alzheimers disease. Biomarkers Med 2007; 1: 59-78.
-
(2007)
Biomarkers Med
, vol.1
, pp. 59-78
-
-
Andreasson, U.1
Portelius, E.2
Andersson, M.E.3
Blennow, K.4
Zetterberg, H.5
-
3
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG, Wong CW. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1984; 120: 885-890.
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
4
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 1985; 82: 4245-4249.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
5
-
-
0026595567
-
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs
-
Burdick D, Soreghan B, Kwon M, et al. Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. J Biol Chem 1992; 267: 546-554.
-
(1992)
J Biol Chem
, vol.267
, pp. 546-554
-
-
Burdick, D.1
Soreghan, B.2
Kwon, M.3
-
6
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett JT, Berger EP, Lansbury PT Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32: 4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
7
-
-
0028169925
-
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
-
Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43). Neuron 1994; 13: 45-53.
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
Mizusawa, H.4
Nukina, N.5
Ihara, Y.6
-
8
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol 2003; 2: 605-613.
-
(2003)
Lancet Neurol
, vol.2
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
9
-
-
34848921838
-
Impact of amyloid imaging on drug development in Alzheimer's disease
-
Mathis CA, Lopresti BJ, Klunk WE. Impact of amyloid imaging on drug development in Alzheimer's disease. Nucl Med Biol 2007; 34: 809-822.
-
(2007)
Nucl Med Biol
, vol.34
, pp. 809-822
-
-
Mathis, C.A.1
Lopresti, B.J.2
Klunk, W.E.3
-
10
-
-
4344673143
-
Biomarkers of Alzheimer disease in plasma
-
Irizarry MC. Biomarkers of Alzheimer disease in plasma. NeuroRx 2004; 1: 226-234.
-
(2004)
NeuroRx
, vol.1
, pp. 226-234
-
-
Irizarry, M.C.1
-
11
-
-
33745920161
-
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo
-
Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med 2006; 12: 856-861.
-
(2006)
Nat Med
, vol.12
, pp. 856-861
-
-
Bateman, R.J.1
Munsell, L.Y.2
Morris, J.C.3
Swarm, R.4
Yarasheski, K.E.5
Holtzman, D.M.6
-
12
-
-
33644832047
-
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta 42 in humans
-
Fagan AM, Mintun MA, Mach RH, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta 42 in humans. Ann Neurol 2006; 59: 512-519.
-
(2006)
Ann Neurol
, vol.59
, pp. 512-519
-
-
Fagan, A.M.1
Mintun, M.A.2
Mach, R.H.3
-
13
-
-
49349092320
-
PET imaging of amyloid deposition in patients with mild cognitive impairment
-
in press
-
Forsberg A, Engler H, Almkvist O, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging 2008, in press.
-
(2008)
Neurobiol Aging
-
-
Forsberg, A.1
Engler, H.2
Almkvist, O.3
-
14
-
-
0037465449
-
CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study
-
Strozyk D, Blennow K, White LR, Launer LJ. CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study. Neurology 2003; 60: 652-656.
-
(2003)
Neurology
, vol.60
, pp. 652-656
-
-
Strozyk, D.1
Blennow, K.2
White, L.R.3
Launer, L.J.4
-
15
-
-
33947223454
-
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
-
Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 2007; 64: 343-349.
-
(2007)
Arch Neurol
, vol.64
, pp. 343-349
-
-
Fagan, A.M.1
Roe, C.M.2
Xiong, C.3
Mintun, M.A.4
Morris, J.C.5
Holtzman, D.M.6
-
16
-
-
32544435900
-
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: A follow-up study
-
Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: A follow-up study. Lancet Neurol 2006; 5: 228-234.
-
(2006)
Lancet Neurol
, vol.5
, pp. 228-234
-
-
Hansson, O.1
Zetterberg, H.2
Buchhave, P.3
Londos, E.4
Blennow, K.5
Minthon, L.6
-
17
-
-
16844382811
-
CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment
-
Herukka SK, Hallikainen M, Soininen H, Pirttila T. CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment. Neurology 2005; 64: 1294-1297.
-
(2005)
Neurology
, vol.64
, pp. 1294-1297
-
-
Herukka, S.K.1
Hallikainen, M.2
Soininen, H.3
Pirttila, T.4
-
18
-
-
0242627597
-
Cerebrospinal fluid markers for prediction of Alzheimer's disease
-
Zetterberg H, Wahlund LO, Blennow K. Cerebrospinal fluid markers for prediction of Alzheimer's disease. Neurosci Lett 2003; 352: 67-69.
-
(2003)
Neurosci Lett
, vol.352
, pp. 67-69
-
-
Zetterberg, H.1
Wahlund, L.O.2
Blennow, K.3
-
19
-
-
0027373325
-
Low frequency of post-lumbar puncture headache in demented patients
-
Blennow K, Wallin A, Hager O. Low frequency of post-lumbar puncture headache in demented patients. Acta Neurol Scand 1993; 88: 221-223.
-
(1993)
Acta Neurol Scand
, vol.88
, pp. 221-223
-
-
Blennow, K.1
Wallin, A.2
Hager, O.3
-
21
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D, Eckman C, Jensen M, et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 1996; 2: 864-870.
-
(1996)
Nat Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
-
22
-
-
0242412140
-
Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: Relation to age, mortality, and risk
-
Mayeux R, Honig LS, Tang MX, et al. Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: Relation to age, mortality, and risk. Neurology 2003; 61: 1185-1190.
-
(2003)
Neurology
, vol.61
, pp. 1185-1190
-
-
Mayeux, R.1
Honig, L.S.2
Tang, M.X.3
-
23
-
-
33745959062
-
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: A prospective case-cohort study
-
van Oijen M, Hofman A, Soares HD, Koudstaal PJ, Breteler MM. Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: A prospective case-cohort study. Lancet Neurol 2006; 5: 655-660.
-
(2006)
Lancet Neurol
, vol.5
, pp. 655-660
-
-
van Oijen, M.1
Hofman, A.2
Soares, H.D.3
Koudstaal, P.J.4
Breteler, M.M.5
-
24
-
-
39049156035
-
Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: A prospective, population-based cohort study
-
Sundelof J, Giedraitis V, Irizarry MC, et al. Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: A prospective, population-based cohort study. Arch Neurol 2008; 65: 256-263.
-
(2008)
Arch Neurol
, vol.65
, pp. 256-263
-
-
Sundelof, J.1
Giedraitis, V.2
Irizarry, M.C.3
-
25
-
-
33947282076
-
Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
-
Graff-Radford NR, Crook JE, Lucas J, et al. Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol 2007; 64: 354-362.
-
(2007)
Arch Neurol
, vol.64
, pp. 354-362
-
-
Graff-Radford, N.R.1
Crook, J.E.2
Lucas, J.3
-
26
-
-
16944364644
-
Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma
-
Biere AL, Ostaszewski B, Stimson ER, Hyman BT, Maggio JE, Selkoe DJ. Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma. J Biol Chem 1996; 271: 32916-32922.
-
(1996)
J Biol Chem
, vol.271
, pp. 32916-32922
-
-
Biere, A.L.1
Ostaszewski, B.2
Stimson, E.R.3
Hyman, B.T.4
Maggio, J.E.5
Selkoe, D.J.6
-
27
-
-
0032539723
-
Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation
-
Hughes SR, Khorkova O, Goyal S, et al. Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation. Proc Natl Acad Sci U S A 1998; 95: 3275-3280.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3275-3280
-
-
Hughes, S.R.1
Khorkova, O.2
Goyal, S.3
-
28
-
-
34948888151
-
Clearance of amyloid-beta by circulating lipoprotein receptors
-
Sagare A, Deane R, Bell RD, et al. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med 2007; 13: 1029-1031.
-
(2007)
Nat Med
, vol.13
, pp. 1029-1031
-
-
Sagare, A.1
Deane, R.2
Bell, R.D.3
-
29
-
-
0035907123
-
Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease
-
Mehta PD, Pirttila T, Patrick BA, Barshatzky M, Mehta SP. Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease. Neurosci Lett 2001; 304: 102-106.
-
(2001)
Neurosci Lett
, vol.304
, pp. 102-106
-
-
Mehta, P.D.1
Pirttila, T.2
Patrick, B.A.3
Barshatzky, M.4
Mehta, S.P.5
-
30
-
-
0033637408
-
Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma
-
Vanderstichele H, Van Kerschaver E, Hesse C, et al. Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma. Amyloid 2000; 7: 245-258.
-
(2000)
Amyloid
, vol.7
, pp. 245-258
-
-
Vanderstichele, H.1
Van Kerschaver, E.2
Hesse, C.3
-
31
-
-
34147105393
-
Plasma Abeta levels do not reflect brain Abeta levels
-
Freeman SH, Raju S, Hyman BT, Frosch MP, Irizarry MC. Plasma Abeta levels do not reflect brain Abeta levels. J Neuropathol Exp Neurol 2007; 66: 264-271.
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 264-271
-
-
Freeman, S.H.1
Raju, S.2
Hyman, B.T.3
Frosch, M.P.4
Irizarry, M.C.5
-
32
-
-
35448942648
-
The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease
-
Giedraitis V, Sundelof J, Irizarry MC, et al. The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease. Neurosci Lett 2007; 427: 127-131.
-
(2007)
Neurosci Lett
, vol.427
, pp. 127-131
-
-
Giedraitis, V.1
Sundelof, J.2
Irizarry, M.C.3
-
33
-
-
55649111504
-
-
Younkin, S.G., Younkin, L.H., Graff-Radford, N., Crook, J.E., Lucas, J.A.: WO06014723 (2006).
-
Younkin, S.G., Younkin, L.H., Graff-Radford, N., Crook, J.E., Lucas, J.A.: WO06014723 (2006).
-
-
-
-
34
-
-
55649107631
-
-
US20080057593
-
Vanderstichele, H., Vanmechelen, E., De Meyer, G., Blennow, K., Kostanjevecki, V.: US20080057593 (2008).
-
(2008)
-
-
Vanderstichele, H.1
Vanmechelen, E.2
De Meyer, G.3
Blennow, K.4
Kostanjevecki, V.5
-
35
-
-
21544458621
-
Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers
-
Siemers E, Skinner M, Dean RA, et al. Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers. Clin Neuropharmacol 2005; 28: 126-132.
-
(2005)
Clin Neuropharmacol
, vol.28
, pp. 126-132
-
-
Siemers, E.1
Skinner, M.2
Dean, R.A.3
-
36
-
-
33645013015
-
Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease
-
Siemers ER, Quinn JF, Kaye J, et al. Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease. Neurology 2006; 66: 602-604.
-
(2006)
Neurology
, vol.66
, pp. 602-604
-
-
Siemers, E.R.1
Quinn, J.F.2
Kaye, J.3
-
37
-
-
4644267911
-
Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment
-
Assini A, Cammarata S, Vitali A, et al. Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment. Neurology 2004; 63: 828-831.
-
(2004)
Neurology
, vol.63
, pp. 828-831
-
-
Assini, A.1
Cammarata, S.2
Vitali, A.3
-
38
-
-
36048982129
-
Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: Prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine
-
Blasko I, Jellinger K, Kemmler G, et al. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: Prediction by plasma amyloid beta 42, medial temporal lobe atrophy and homocysteine. Neurobiol Aging 2008; 29: 1-11.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1-11
-
-
Blasko, I.1
Jellinger, K.2
Kemmler, G.3
-
39
-
-
0037699792
-
Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels
-
Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, Irizarry MC. Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels. Arch Neurol 2003; 60: 958-964.
-
(2003)
Arch Neurol
, vol.60
, pp. 958-964
-
-
Fukumoto, H.1
Tennis, M.2
Locascio, J.J.3
Hyman, B.T.4
Growdon, J.H.5
Irizarry, M.C.6
-
40
-
-
35748972941
-
The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels
-
Abdullah L, Paris D, Luis C, et al. The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels. Neurosci Lett 2007; 428: 53-58.
-
(2007)
Neurosci Lett
, vol.428
, pp. 53-58
-
-
Abdullah, L.1
Paris, D.2
Luis, C.3
|