Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression

Brain, Behavior, and Immunity

Volumn 21, Issue 1, 2007, Pages 9-19

  Pace, Thaddeus W W ^a   Hu, Fang ^a   Miller, Andrew H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP; Cyclooxygenase; Cytokine; Depression; Glucocorticoid receptor; HPA axis; Mitogen activated protein kinase; Nuclear factor B; Protein kinase A; Signal transducers and activators of transcription; Signal transduction

Indexed keywords

ALPHA INTERFERON; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CELECOXIB; CITALOPRAM; CLOMIPRAMINE; CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP; CYTOKINE; DESIPRAMINE; DEXAMETHASONE; FLUOXETINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NONSTEROID ANTIINFLAMMATORY AGENT; PAROXETINE; PHOSPHOLIPASE; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; REBOXETINE; STAT PROTEIN;

ADRENERGIC SYSTEM; ANHEDONIA; ANXIETY; CANCER; CELL PROLIFERATION; COGNITIVE DEFECT; DECREASED APPETITE; DEPRESSION; DNA POLYMORPHISM; FATIGUE; HEPATITIS C; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFLAMMATION; IRRITABILITY; MAJOR DEPRESSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PSYCHOMOTOR RETARDATION; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SLEEP DISORDER; STRESS;

CYTOKINES; DEPRESSIVE DISORDER, MAJOR; ENDOCRINE SYSTEM DISEASES; HUMANS; INFLAMMATION; NEUROIMMUNOMODULATION; RECEPTORS, GLUCOCORTICOID; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL;

EID: 33845291521     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2006.08.009     Document Type: Review

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