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Volumn 66, Issue 2, 2009, Pages 190-199

A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer Disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY; CYSTEINE; DISULFIDE; MERCAPTOETHANOL; MONOMER; OLIGOMER; PRESENILIN; SERINE;

EID: 60549107033     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneurol.2008.565     Document Type: Article
Times cited : (192)

References (39)
  • 1
    • 33645775230 scopus 로고    scopus 로고
    • Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry
    • portelius E, Westman-Brinkmalm A, Zetterberg H, Blennow K. Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry. J proteome Res. 2006;5(4):1010-1016.
    • (2006) J proteome Res , vol.5 , Issue.4 , pp. 1010-1016
    • portelius, E.1    Westman-Brinkmalm, A.2    Zetterberg, H.3    Blennow, K.4
  • 2
    • 0027379395 scopus 로고    scopus 로고
    • Vigo-pelfrey C, Lee D, Keim pS, Lieberburg I, Schenk D. Characterization of p-amyloid peptide from human cerebrospinal fluid. J Neurochem. 1993;61(5): 1965-1968.
    • Vigo-pelfrey C, Lee D, Keim pS, Lieberburg I, Schenk D. Characterization of p-amyloid peptide from human cerebrospinal fluid. J Neurochem. 1993;61(5): 1965-1968.
  • 3
    • 0027258525 scopus 로고    scopus 로고
    • Jarrett JT, Berger Ep, Lansbury pT Jr. The carboxy terminus of the p amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry. 1993;32(18):4693-4697.
    • Jarrett JT, Berger Ep, Lansbury pT Jr. The carboxy terminus of the p amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry. 1993;32(18):4693-4697.
  • 4
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron. 2004;44(1):181-193.
    • (2004) Neuron , vol.44 , Issue.1 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 5
    • 36048982129 scopus 로고    scopus 로고
    • Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: Prediction by plasma amyloid p 42, medial temporal lobe atrophy and homocysteine
    • Blasko I, Jellinger K, Kemmler G, et al. Conversion from cognitive health to mild cognitive impairment and Alzheimer's disease: prediction by plasma amyloid p 42, medial temporal lobe atrophy and homocysteine. Neurobiol Aging. 2008; 29(1):1-11.
    • (2008) Neurobiol Aging , vol.29 , Issue.1 , pp. 1-11
    • Blasko, I.1    Jellinger, K.2    Kemmler, G.3
  • 6
    • 0032869023 scopus 로고    scopus 로고
    • plasma amyloid p-peptide 1-42 and incipient Alzheimer's disease
    • Mayeux R, Tang MX, Jacobs DM, et al. plasma amyloid p-peptide 1-42 and incipient Alzheimer's disease. Ann Neurol. 1999;46(3):412-416.
    • (1999) Ann Neurol , vol.46 , Issue.3 , pp. 412-416
    • Mayeux, R.1    Tang, M.X.2    Jacobs, D.M.3
  • 7
    • 0242412140 scopus 로고    scopus 로고
    • plasma Aβ40 and Aβ42 and Alzheimer's disease: Relation to age, mortality, and risk
    • Mayeux R, Honig LS, Tang MX, et al. plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology. 2003;61(9):1185-1190.
    • (2003) Neurology , vol.61 , Issue.9 , pp. 1185-1190
    • Mayeux, R.1    Honig, L.S.2    Tang, M.X.3
  • 8
    • 34447275455 scopus 로고    scopus 로고
    • Elevated plasma β-amyloid peptide Aβ(42) levels, incident dementia, and mortality in Down syndrome
    • Schupf N, patel B, pang D, et al. Elevated plasma β-amyloid peptide Aβ(42) levels, incident dementia, and mortality in Down syndrome. Arch Neurol. 2007; 64(7):1007-1013.
    • (2007) Arch Neurol , vol.64 , Issue.7 , pp. 1007-1013
    • Schupf, N.1    patel, B.2    pang, D.3
  • 9
    • 16044373524 scopus 로고    scopus 로고
    • Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the pre-senilin 1 and 2 and App mutations linked to familial Alzheimer's disease
    • Scheuner D, Eckman C, Jensen M, et al. Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the pre-senilin 1 and 2 and App mutations linked to familial Alzheimer's disease. Nat Med. 1996;2(8):864-870.
    • (1996) Nat Med , vol.2 , Issue.8 , pp. 864-870
    • Scheuner, D.1    Eckman, C.2    Jensen, M.3
  • 10
    • 47549117283 scopus 로고    scopus 로고
    • Biochemical markers in persons with preclinical familial Alzheimer disease
    • Ringman JM, Younkin SG, pratico D, et al. Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology. 2008;71(2):85-92.
    • (2008) Neurology , vol.71 , Issue.2 , pp. 85-92
    • Ringman, J.M.1    Younkin, S.G.2    pratico, D.3
  • 11
    • 0034703979 scopus 로고    scopus 로고
    • Ertekin-Taner N, Graff-Radford N, Younkin LH, et al. Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset alzheimer's disease pedigrees. Science. 2000;290(5500):2303-2304.
    • Ertekin-Taner N, Graff-Radford N, Younkin LH, et al. Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset alzheimer's disease pedigrees. Science. 2000;290(5500):2303-2304.
  • 12
    • 0034936365 scopus 로고    scopus 로고
    • Ertekin-Taner N, Graff-Radford N, Younkin LH, et al. Heritability of plasma amyloid β in typical late-onset alzheimer's disease pedigrees. Genet Epidemiol. 2001; 21(1):19-30.
    • Ertekin-Taner N, Graff-Radford N, Younkin LH, et al. Heritability of plasma amyloid β in typical late-onset alzheimer's disease pedigrees. Genet Epidemiol. 2001; 21(1):19-30.
  • 13
    • 39749090577 scopus 로고    scopus 로고
    • Ertekin-Taner N, Younkin LH, Yager DM, et al. plasma amyloid β protein is elevated in late-onset Alzheimer disease families. Neurology. 2008;70(8):596-606.
    • Ertekin-Taner N, Younkin LH, Yager DM, et al. plasma amyloid β protein is elevated in late-onset Alzheimer disease families. Neurology. 2008;70(8):596-606.
  • 14
    • 35948933394 scopus 로고    scopus 로고
    • Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    • Ray S, Britschgi M, Herbert C, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med. 2007;13 (11):1359-1362.
    • (2007) Nat Med , vol.13 , Issue.11 , pp. 1359-1362
    • Ray, S.1    Britschgi, M.2    Herbert, C.3
  • 15
    • 33750596715 scopus 로고    scopus 로고
    • proteome-based plasma biomarkers for Alzheimer's disease
    • Hye A, Lynham S, Thambisetty M, et al. proteome-based plasma biomarkers for Alzheimer's disease. Brain. 2006;129(pt 11):3042-3050.
    • (2006) Brain , vol.129 , Issue.PART 11 , pp. 3042-3050
    • Hye, A.1    Lynham, S.2    Thambisetty, M.3
  • 16
    • 4644267911 scopus 로고    scopus 로고
    • plasma levels of amyloid β-protein 42 are increased in women with mild cognitive impairment
    • Assini A, Cammarata S, Vitali A, et al. plasma levels of amyloid β-protein 42 are increased in women with mild cognitive impairment. Neurology. 2004;63(5):828-831.
    • (2004) Neurology , vol.63 , Issue.5 , pp. 828-831
    • Assini, A.1    Cammarata, S.2    Vitali, A.3
  • 17
    • 39049156035 scopus 로고    scopus 로고
    • plasma β amyloid and the risk of Alzheimer disease and dementia in elderly men: A prospective, population-based cohort study
    • Sundelöf J, Giedraitis V, I rizarry MC, et al. plasma β amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study. Arch Neurol. 2008;65(2):256-263.
    • (2008) Arch Neurol , vol.65 , Issue.2 , pp. 256-263
    • Sundelöf, J.1    Giedraitis, V.2    rizarry MC, I.3
  • 18
    • 33947282076 scopus 로고    scopus 로고
    • Association of low plasma Aβ42/ Aβ40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
    • Graff-Radford NR, Crook JE, Lucas J, et al. Association of low plasma Aβ42/ Aβ40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol. 2007;64(3):354-362.
    • (2007) Arch Neurol , vol.64 , Issue.3 , pp. 354-362
    • Graff-Radford, N.R.1    Crook, J.E.2    Lucas, J.3
  • 19
    • 33745959062 scopus 로고    scopus 로고
    • Koudstaal pJ, Breteler MM. plasma Aβ(1-40) and Aβ(1-42) and the risk of dementia: A prospective case-cohort study
    • van Oijen M, Hofman A, Soares HD, Koudstaal pJ, Breteler MM. plasma Aβ(1-40) and Aβ(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol. 2006;5(8):655-660.
    • (2006) Lancet Neurol , vol.5 , Issue.8 , pp. 655-660
    • van Oijen, M.1    Hofman, A.2    Soares, H.D.3
  • 20
    • 77049084060 scopus 로고    scopus 로고
    • Hansson O, Zetterberg H, Blennow K, et al. Evaluation of plasmaAβ(40) and Aβ (42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment [published online ahead of print October 25,2008]. Neurobiol Aging. doi:10.1016/j.neurobiolaging. 2008.09.006.
    • Hansson O, Zetterberg H, Blennow K, et al. Evaluation of plasmaAβ(40) and Aβ (42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment [published online ahead of print October 25,2008]. Neurobiol Aging. doi:10.1016/j.neurobiolaging. 2008.09.006.
  • 21
    • 33750695954 scopus 로고    scopus 로고
    • plasma amyloid-β concentrations in Alzheimer's disease: An alternative hypothesis
    • Fullwood NJ, Hayashi Y, Allsop D. plasma amyloid-β concentrations in Alzheimer's disease: an alternative hypothesis. Lancet Neurol. 2006;5(12):1000-1003.
    • (2006) Lancet Neurol , vol.5 , Issue.12 , pp. 1000-1003
    • Fullwood, N.J.1    Hayashi, Y.2    Allsop, D.3
  • 22
    • 49149124343 scopus 로고    scopus 로고
    • Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
    • Shankar GM, Li S, Mehta TH, et al. Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008;14(8):837-842.
    • (2008) Nat Med , vol.14 , Issue.8 , pp. 837-842
    • Shankar, G.M.1    Li, S.2    Mehta, T.H.3
  • 23
    • 0031020909 scopus 로고    scopus 로고
    • Amyloid precursor protein processing and Aβ42 deposition in a transgenic mouse model of Alzheimer disease. proc
    • Johnson-Wood K, Lee M, Motter R, et al. Amyloid precursor protein processing and Aβ42 deposition in a transgenic mouse model of Alzheimer disease. proc Natl Acad Sci USA. 1997;94(4):1550-1555.
    • (1997) Natl Acad Sci USA , vol.94 , Issue.4 , pp. 1550-1555
    • Johnson-Wood, K.1    Lee, M.2    Motter, R.3
  • 24
    • 0027459686 scopus 로고    scopus 로고
    • Seubert p, Oltersdorf T, Lee MG, et al. Secretion of β-amyloid precursor protein cleaved at the amino-terminus of the β-amyloid peptide. Nature. 1993;361 (6409):260-263.
    • Seubert p, Oltersdorf T, Lee MG, et al. Secretion of β-amyloid precursor protein cleaved at the amino-terminus of the β-amyloid peptide. Nature. 1993;361 (6409):260-263.
  • 25
    • 16944365745 scopus 로고    scopus 로고
    • Enhanced production and oligomerization of the 42-residue amyloid p-protein by Chinese hamster ovary cells stably expressing mutant presenilins
    • Xia W, Zhang J, Kholodenko D, et al. Enhanced production and oligomerization of the 42-residue amyloid p-protein by Chinese hamster ovary cells stably expressing mutant presenilins. J Biol Chem. 1997;272(12):7977-7982.
    • (1997) J Biol Chem , vol.272 , Issue.12 , pp. 7977-7982
    • Xia, W.1    Zhang, J.2    Kholodenko, D.3
  • 26
    • 0032480771 scopus 로고    scopus 로고
    • The presence of amyloid β-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells
    • Morishima-Kawashima M, Ihara Y. The presence of amyloid β-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells. Biochemistry. 1998;37(44):15247-15253.
    • (1998) Biochemistry , vol.37 , Issue.44 , pp. 15247-15253
    • Morishima-Kawashima, M.1    Ihara, Y.2
  • 27
    • 0034647786 scopus 로고    scopus 로고
    • El-Agnaf OM, Mahil DS, patel Bp, Austen BM. Oligomerization and toxicity of β-amyloid-42 implicated in Alzheimer's disease. Biochem Biophys Res Commun. 2000;273(3):1003-1007.
    • El-Agnaf OM, Mahil DS, patel Bp, Austen BM. Oligomerization and toxicity of β-amyloid-42 implicated in Alzheimer's disease. Biochem Biophys Res Commun. 2000;273(3):1003-1007.
  • 28
    • 0033563079 scopus 로고    scopus 로고
    • Inhibition of fibril formation in β-amyloid peptide by a novel series of benzofurans
    • Howlett DR, perry AE, Godfrey F, et al. Inhibition of fibril formation in β-amyloid peptide by a novel series of benzofurans. Biochem J. 1999;340(pt 1):283-289.
    • (1999) Biochem J , vol.340 , Issue.PART 1 , pp. 283-289
    • Howlett, D.R.1    perry, A.E.2    Godfrey, F.3
  • 29
    • 38949121975 scopus 로고    scopus 로고
    • Hu MK, Liao YF, Chen JF, et al. New 1,2,3,4-tetrahydroisoquinoline derivatives as modulators of proteolytic cleavage of amyloid precursor proteins. Bioorg Med Chem. 2008;16(4):1957-1965.
    • Hu MK, Liao YF, Chen JF, et al. New 1,2,3,4-tetrahydroisoquinoline derivatives as modulators of proteolytic cleavage of amyloid precursor proteins. Bioorg Med Chem. 2008;16(4):1957-1965.
  • 30
    • 0028952749 scopus 로고
    • Aggregation of secreted amyloid β-protein into sodium dodecyl sulfate-stable oligomers in cell culture
    • podlisny MB, Ostaszewski BL, Squazzo SL, et al. Aggregation of secreted amyloid β-protein into sodium dodecyl sulfate-stable oligomers in cell culture. J Biol Chem. 1995;270(16):9564-9570.
    • (1995) J Biol Chem , vol.270 , Issue.16 , pp. 9564-9570
    • podlisny, M.B.1    Ostaszewski, B.L.2    Squazzo, S.L.3
  • 31
    • 0030799122 scopus 로고    scopus 로고
    • Amyloid β-protein fibrillogenesis: Detection of aprotofib rillar intermediate
    • Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB. Amyloid β-protein fibrillogenesis: detection of aprotofib rillar intermediate. J Biol Chem. 1997;272(35):22364-22372.
    • (1997) J Biol Chem , vol.272 , Issue.35 , pp. 22364-22372
    • Walsh, D.M.1    Lomakin, A.2    Benedek, G.B.3    Condron, M.M.4    Teplow, D.B.5
  • 32
    • 14044279957 scopus 로고    scopus 로고
    • Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. proc
    • Georganopoulou DG, Chang L, Nam JM, et al. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. proc Natl Acad Sci U S A. 2005;102(7):2273-2276.
    • (2005) Natl Acad Sci U S A , vol.102 , Issue.7 , pp. 2273-2276
    • Georganopoulou, D.G.1    Chang, L.2    Nam, J.M.3
  • 33
    • 33645220400 scopus 로고    scopus 로고
    • Targeting amyloid-β peptide (Aβ) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Aβ precursor protein (App) transgenic mice
    • Lee EB, Leng LZ, Zhang B, et al. Targeting amyloid-β peptide (Aβ) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Aβ precursor protein (App) transgenic mice. J Biol Chem. 2006;281(7):4292-4299.
    • (2006) J Biol Chem , vol.281 , Issue.7 , pp. 4292-4299
    • Lee, E.B.1    Leng, L.Z.2    Zhang, B.3
  • 34
    • 34548614101 scopus 로고    scopus 로고
    • Sensitive ELISA detection of amyloid-β protofibrils in biological samples
    • Englund H, Sehlin D, Johansson AS, et al. Sensitive ELISA detection of amyloid-β protofibrils in biological samples. J Neurochem. 2007;103(1):334-345.
    • (2007) J Neurochem , vol.103 , Issue.1 , pp. 334-345
    • Englund, H.1    Sehlin, D.2    Johansson, A.S.3
  • 35
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospi-nal fluid tau/β-amyloid(42) ratio as a prediction of cognitive decline in nonde-mented older adults
    • Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM. Cerebrospi-nal fluid tau/β-amyloid(42) ratio as a prediction of cognitive decline in nonde-mented older adults. Arch Neurol. 2007;64(3):343-349.
    • (2007) Arch Neurol , vol.64 , Issue.3 , pp. 343-349
    • Fagan, A.M.1    Roe, C.M.2    Xiong, C.3    Mintun, M.A.4    Morris, J.C.5    Holtzman, D.M.6
  • 36
    • 32544435900 scopus 로고    scopus 로고
    • Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study [published correction appears in Lancet Neurol. 2006;5(4):293]. Lancet Neurol. 2006;5(3):228-234.
    • Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study [published correction appears in Lancet Neurol. 2006;5(4):293]. Lancet Neurol. 2006;5(3):228-234.
  • 37
    • 71349085112 scopus 로고    scopus 로고
    • Stomrud E, Hansson O, Minthon L, Blennow K, Rosen I, Londos E. Slowing of EEG correlates with CSF biomarkers and reduced cognitive speed in elderly with normal cognition over 4 years [published online ahead of print May 5, 2008]. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2008.03.025.
    • Stomrud E, Hansson O, Minthon L, Blennow K, Rosen I, Londos E. Slowing of EEG correlates with CSF biomarkers and reduced cognitive speed in elderly with normal cognition over 4 years [published online ahead of print May 5, 2008]. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2008.03.025.
  • 38
    • 0036738076 scopus 로고    scopus 로고
    • A mathematical model of the impact of novel treatments on the Aβ burden in the Alzheimer's brain, CSF and plasma
    • Craft DL, Wein LM, Selkoe DJ. A mathematical model of the impact of novel treatments on the Aβ burden in the Alzheimer's brain, CSF and plasma. Bull Math Biol. 2002;64(5):1011-1031.
    • (2002) Bull Math Biol , vol.64 , Issue.5 , pp. 1011-1031
    • Craft, D.L.1    Wein, L.M.2    Selkoe, D.J.3
  • 39
    • 39749105380 scopus 로고    scopus 로고
    • Davies p. Toward a plasma marker for Alzheimer disease: Some progress, but still a long way to go
    • Crystal HA, Davies p. Toward a plasma marker for Alzheimer disease: some progress, but still a long way to go. Neurology. 2008;70(8):586-587.
    • (2008) Neurology , vol.70 , Issue.8 , pp. 586-587
    • Crystal, H.A.1


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