-
1
-
-
84858702540
-
The worldwide epidemiology of type 2 diabetes mellitus - present and future perspectives
-
Chen L., Magliano D.J., Zimmet P.Z. The worldwide epidemiology of type 2 diabetes mellitus - present and future perspectives. Nature Reviews Endocrinology 2012, 8:228-236.
-
(2012)
Nature Reviews Endocrinology
, vol.8
, pp. 228-236
-
-
Chen, L.1
Magliano, D.J.2
Zimmet, P.Z.3
-
2
-
-
4143151942
-
Pathogenesis of type 2 diabetes mellitus
-
ix
-
DeFronzo R.A. Pathogenesis of type 2 diabetes mellitus. Medical Clinics of North America 2004, 88:787-835. ix.
-
(2004)
Medical Clinics of North America
, vol.88
, pp. 787-835
-
-
DeFronzo, R.A.1
-
3
-
-
0026554640
-
Molecular physiology and genetics of NIDDM. Importance of metabolic staging
-
Granner D.K., O'Brien R.M. Molecular physiology and genetics of NIDDM. Importance of metabolic staging. Diabetes Care 1992, 15:369-395.
-
(1992)
Diabetes Care
, vol.15
, pp. 369-395
-
-
Granner, D.K.1
O'Brien, R.M.2
-
4
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C., Bogardus C., Mott D.M., Pratley R.E. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. The Journal of Clinical Investigation 1999, 104:787-794.
-
(1999)
The Journal of Clinical Investigation
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
5
-
-
0031792118
-
Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue
-
Lauro D., Kido Y., Castle A.L., Zarnowski M.J., Hayashi H., Ebina Y., et al. Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue. Nature Genetics 1998, 20:294-298.
-
(1998)
Nature Genetics
, vol.20
, pp. 294-298
-
-
Lauro, D.1
Kido, Y.2
Castle, A.L.3
Zarnowski, M.J.4
Hayashi, H.5
Ebina, Y.6
-
6
-
-
0034034229
-
Glucose-6-phosphatase flux invitro is increased in type 2 diabetes
-
Clore J.N., Stillman J., Sugerman H. Glucose-6-phosphatase flux invitro is increased in type 2 diabetes. Diabetes 2000, 49:969-974.
-
(2000)
Diabetes
, vol.49
, pp. 969-974
-
-
Clore, J.N.1
Stillman, J.2
Sugerman, H.3
-
7
-
-
0024511329
-
Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
-
Consoli A., Nurjhan N., Capani F., Gerich J. Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes 1989, 38:550-557.
-
(1989)
Diabetes
, vol.38
, pp. 550-557
-
-
Consoli, A.1
Nurjhan, N.2
Capani, F.3
Gerich, J.4
-
8
-
-
50249114066
-
Hepatic dysfunction and insulin insensitivity intype 2 diabetes mellitus: a critical target for insulin-sensitizing agents
-
Home P.D., Pacini G. Hepatic dysfunction and insulin insensitivity intype 2 diabetes mellitus: a critical target for insulin-sensitizing agents. Diabetes, Obesity and Metabolism 2008, 10:699-718.
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, pp. 699-718
-
-
Home, P.D.1
Pacini, G.2
-
9
-
-
0026488079
-
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclearmagnetic resonance study
-
Magnusson I., Rothman D.L., Katz L.D., Shulman R.G., Shulman G.I. Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclearmagnetic resonance study. The Journal of Clinical Investigation 1992, 90:1323-1327.
-
(1992)
The Journal of Clinical Investigation
, vol.90
, pp. 1323-1327
-
-
Magnusson, I.1
Rothman, D.L.2
Katz, L.D.3
Shulman, R.G.4
Shulman, G.I.5
-
10
-
-
78049259220
-
Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy
-
Rizza R.A. Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy. Diabetes 2010, 59:2697-2707.
-
(2010)
Diabetes
, vol.59
, pp. 2697-2707
-
-
Rizza, R.A.1
-
12
-
-
79951962147
-
CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
-
Altarejos J.Y., Montminy M. CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nature Reviews Molecular Cell Biology 2011, 12:141-151.
-
(2011)
Nature Reviews Molecular Cell Biology
, vol.12
, pp. 141-151
-
-
Altarejos, J.Y.1
Montminy, M.2
-
14
-
-
7244239341
-
Anovel role for glucose 6-phosphatase in the small intestine in the control of glucose homeostasis
-
Mithieux G., Rajas F., Gautier-Stein A. Anovel role for glucose 6-phosphatase in the small intestine in the control of glucose homeostasis. The Journal of Biological Chemistry 2004, 279:44231-44234.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 44231-44234
-
-
Mithieux, G.1
Rajas, F.2
Gautier-Stein, A.3
-
15
-
-
77956954932
-
Hypothalamic integration of portal glucose signals and control of food intake and insulin sensitivity
-
Delaere F., Magnan C., Mithieux G. Hypothalamic integration of portal glucose signals and control of food intake and insulin sensitivity. Diabetes & Metabolism 2010, 36:257-262.
-
(2010)
Diabetes & Metabolism
, vol.36
, pp. 257-262
-
-
Delaere, F.1
Magnan, C.2
Mithieux, G.3
-
16
-
-
84880935872
-
Nutrient control of hunger by extrinsic gastrointestinal neurons
-
Mithieux G. Nutrient control of hunger by extrinsic gastrointestinal neurons. Trends in Endocrinology & Metabolism (TEM) 2013, 24:378-384.
-
(2013)
Trends in Endocrinology & Metabolism (TEM)
, vol.24
, pp. 378-384
-
-
Mithieux, G.1
-
17
-
-
84864283726
-
Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake
-
Duraffourd C., De Vadder F., Goncalves D., Delaere F., Penhoat A., Brusset B., et al. Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake. Cell 2012, 150:377-388.
-
(2012)
Cell
, vol.150
, pp. 377-388
-
-
Duraffourd, C.1
De Vadder, F.2
Goncalves, D.3
Delaere, F.4
Penhoat, A.5
Brusset, B.6
-
18
-
-
59649108433
-
Proteinfeeding promotes redistribution of endogenous glucose production tothe kidney and potentiates its suppression by insulin
-
Pillot B., Soty M., Gautier-Stein A., Zitoun C., Mithieux G. Proteinfeeding promotes redistribution of endogenous glucose production tothe kidney and potentiates its suppression by insulin. Endocrinology 2009, 150:616-624.
-
(2009)
Endocrinology
, vol.150
, pp. 616-624
-
-
Pillot, B.1
Soty, M.2
Gautier-Stein, A.3
Zitoun, C.4
Mithieux, G.5
-
19
-
-
84892814749
-
Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
-
De Vadder F., Kovatcheva-Datchary P., Goncalves D., Vinera J., Zitoun C., Duchampt A., et al. Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits. Cell 2014, 156:84-96.
-
(2014)
Cell
, vol.156
, pp. 84-96
-
-
De Vadder, F.1
Kovatcheva-Datchary, P.2
Goncalves, D.3
Vinera, J.4
Zitoun, C.5
Duchampt, A.6
-
20
-
-
82255185902
-
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon
-
Mutel E., Gautier-Stein A., Abdul-Wahed A., Amigó-Correig M., Zitoun C., Stefanutti A., et al. Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes 2011, 60:3121-3131.
-
(2011)
Diabetes
, vol.60
, pp. 3121-3131
-
-
Mutel, E.1
Gautier-Stein, A.2
Abdul-Wahed, A.3
Amigó-Correig, M.4
Zitoun, C.5
Stefanutti, A.6
-
21
-
-
79951672283
-
Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas
-
Mutel E., Abdul-Wahed A., Ramamonjisoa N., Stefanutti A., Houberdon I., Cavassila S., et al. Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas. Journal of Hepatology 2011, 54:529-537.
-
(2011)
Journal of Hepatology
, vol.54
, pp. 529-537
-
-
Mutel, E.1
Abdul-Wahed, A.2
Ramamonjisoa, N.3
Stefanutti, A.4
Houberdon, I.5
Cavassila, S.6
-
22
-
-
67649823642
-
FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
-
Potthoff M.J., Inagaki T., Satapati S., Ding X., He T., Goetz R., et al. FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:10853-10858.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 10853-10858
-
-
Potthoff, M.J.1
Inagaki, T.2
Satapati, S.3
Ding, X.4
He, T.5
Goetz, R.6
-
24
-
-
84908829517
-
Glycogen: determination with amyloglucosidase
-
Bergmeyer HU, Deerfield Beach, FL, US
-
Pfleiderer G. Glycogen: determination with amyloglucosidase. Methods enzym. anal. 1974, 59-62. Bergmeyer HU, Deerfield Beach, FL, US. 2nd ed.
-
(1974)
Methods enzym. anal.
, pp. 59-62
-
-
Pfleiderer, G.1
-
25
-
-
34247372650
-
Immunocytochemical localization of glucose 6-phosphatase and cytosolic phosphoenolpyruvate carboxykinase in gluconeogenic tissues reveals unsuspected metabolic zonation
-
Rajas F., Jourdan-Pineau H., Stefanutti A., Mrad E.A., Iynedjian P.B., Mithieux G. Immunocytochemical localization of glucose 6-phosphatase and cytosolic phosphoenolpyruvate carboxykinase in gluconeogenic tissues reveals unsuspected metabolic zonation. Histochemistry and Cell Biology 2007, 127:555-565.
-
(2007)
Histochemistry and Cell Biology
, vol.127
, pp. 555-565
-
-
Rajas, F.1
Jourdan-Pineau, H.2
Stefanutti, A.3
Mrad, E.A.4
Iynedjian, P.B.5
Mithieux, G.6
-
26
-
-
0642303113
-
Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability
-
Luquet S., Lopez-Soriano J., Holst D., Fredenrich A., Melki J., Rassoulzadegan M., et al. Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 2003, 17:2299-2301.
-
(2003)
FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
, vol.17
, pp. 2299-2301
-
-
Luquet, S.1
Lopez-Soriano, J.2
Holst, D.3
Fredenrich, A.4
Melki, J.5
Rassoulzadegan, M.6
-
27
-
-
31744444102
-
Contribution of intestine and kidney to glucose fluxes in different nutritional states in rat
-
Mithieux G., Gautier-Stein A., Rajas F., Zitoun C. Contribution of intestine and kidney to glucose fluxes in different nutritional states in rat. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 2006, 143:195-200.
-
(2006)
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
, vol.143
, pp. 195-200
-
-
Mithieux, G.1
Gautier-Stein, A.2
Rajas, F.3
Zitoun, C.4
-
28
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
-
Postic C., Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. The Journal of Clinical Investigation 2008, 118:829-838.
-
(2008)
The Journal of Clinical Investigation
, vol.118
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
29
-
-
84878987408
-
Invivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a
-
Ramamonjisoa N., Ratiney H., Mutel E., Guillou H., Mithieux G., Pilleul F., et al. Invivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a. Journal of Lipid Research 2013, 54:2010-2022.
-
(2013)
Journal of Lipid Research
, vol.54
, pp. 2010-2022
-
-
Ramamonjisoa, N.1
Ratiney, H.2
Mutel, E.3
Guillou, H.4
Mithieux, G.5
Pilleul, F.6
-
30
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell B.B., Spiegelman B.M. Towards a molecular understanding of adaptive thermogenesis. Nature 2000, 404:652-660.
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
32
-
-
70949087409
-
P38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice
-
Pogozelski A.R., Geng T., Li P., Yin X., Lira V.A., Zhang M., et al. p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice. PloS One 2009, 4:e7934.
-
(2009)
PloS One
, vol.4
-
-
Pogozelski, A.R.1
Geng, T.2
Li, P.3
Yin, X.4
Lira, V.A.5
Zhang, M.6
-
33
-
-
63849085094
-
Targeting the AMPK pathway for the treatment of type 2 diabetes
-
Viollet B., Lantier L., Devin-Leclerc J., Hebrard S., Amouyal C., Mounier R., et al. Targeting the AMPK pathway for the treatment of type 2 diabetes. Frontiers in Bioscience (Landmark Edition) 2009, 14:3380-3400.
-
(2009)
Frontiers in Bioscience (Landmark Edition)
, vol.14
, pp. 3380-3400
-
-
Viollet, B.1
Lantier, L.2
Devin-Leclerc, J.3
Hebrard, S.4
Amouyal, C.5
Mounier, R.6
-
34
-
-
70349664475
-
Regulation of skeletal muscle physiology and metabolism by peroxisome proliferator-activated receptor delta
-
Ehrenborg E., Krook A. Regulation of skeletal muscle physiology and metabolism by peroxisome proliferator-activated receptor delta. Pharmacological Reviews 2009, 61:373-393.
-
(2009)
Pharmacological Reviews
, vol.61
, pp. 373-393
-
-
Ehrenborg, E.1
Krook, A.2
-
36
-
-
56749171368
-
Regulation of pancreatic beta cell mass by neuronal signals from the liver
-
Imai J., Katagiri H., Yamada T., Ishigaki Y., Suzuki T., Kudo H., et al. Regulation of pancreatic beta cell mass by neuronal signals from the liver. Science 2008, 322:1250-1254.
-
(2008)
Science
, vol.322
, pp. 1250-1254
-
-
Imai, J.1
Katagiri, H.2
Yamada, T.3
Ishigaki, Y.4
Suzuki, T.5
Kudo, H.6
-
37
-
-
33745151403
-
Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity
-
Uno K., Katagiri H., Yamada T., Ishigaki Y., Ogihara T., Imai J., et al. Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity. Science 2006, 312:1656-1659.
-
(2006)
Science
, vol.312
, pp. 1656-1659
-
-
Uno, K.1
Katagiri, H.2
Yamada, T.3
Ishigaki, Y.4
Ogihara, T.5
Imai, J.6
-
38
-
-
50049119700
-
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice
-
Troy S., Soty M., Ribeiro L., Laval L., Migrenne S., Fioramonti X., et al. Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metabolism 2008, 8:201-211.
-
(2008)
Cell Metabolism
, vol.8
, pp. 201-211
-
-
Troy, S.1
Soty, M.2
Ribeiro, L.3
Laval, L.4
Migrenne, S.5
Fioramonti, X.6
-
39
-
-
26244448038
-
Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy
-
Oike Y., Akao M., Kubota Y., Suda T. Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy. Trends in Molecular Medicine 2005, 11:473-479.
-
(2005)
Trends in Molecular Medicine
, vol.11
, pp. 473-479
-
-
Oike, Y.1
Akao, M.2
Kubota, Y.3
Suda, T.4
-
40
-
-
56449125471
-
Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism
-
Kumar K.G., Trevaskis J.L., Lam D.D., Sutton G.M., Koza R.A., Chouljenko V.N., et al. Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metabolism 2008, 8:468-481.
-
(2008)
Cell Metabolism
, vol.8
, pp. 468-481
-
-
Kumar, K.G.1
Trevaskis, J.L.2
Lam, D.D.3
Sutton, G.M.4
Koza, R.A.5
Chouljenko, V.N.6
-
41
-
-
46649121742
-
Hepatocyte growth factor is a novel stimulator of glucose uptake and metabolism in skeletal muscle cells
-
Perdomo G., Martinez-Brocca M.A., Bhatt B.A., Brown N.F., O'Doherty R.M., Garcia-Ocaña A. Hepatocyte growth factor is a novel stimulator of glucose uptake and metabolism in skeletal muscle cells. The Journal of Biological Chemistry 2008, 283:13700-13706.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 13700-13706
-
-
Perdomo, G.1
Martinez-Brocca, M.A.2
Bhatt, B.A.3
Brown, N.F.4
O'Doherty, R.M.5
Garcia-Ocaña, A.6
-
42
-
-
84878433548
-
Circulating fetuin-A and free fatty acidsinteract to predict insulin resistance in humans
-
Stefan N., Häring H.-U. Circulating fetuin-A and free fatty acidsinteract to predict insulin resistance in humans. Nature Medicine 2013, 19:394-395.
-
(2013)
Nature Medicine
, vol.19
, pp. 394-395
-
-
Stefan, N.1
Häring, H.-U.2
-
43
-
-
84876542381
-
Fibroblast growth factor 21 mediates specific glucagon actions
-
Habegger K.M., Stemmer K., Cheng C., Muller T.D., Heppner K.M., Ottaway N., et al. Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes 2013, 62:1453-1463.
-
(2013)
Diabetes
, vol.62
, pp. 1453-1463
-
-
Habegger, K.M.1
Stemmer, K.2
Cheng, C.3
Muller, T.D.4
Heppner, K.M.5
Ottaway, N.6
-
44
-
-
34249711964
-
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states
-
Badman M.K., Pissios P., Kennedy A.R., Koukos G., Flier J.S., Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metabolism 2007, 5:426-437.
-
(2007)
Cell Metabolism
, vol.5
, pp. 426-437
-
-
Badman, M.K.1
Pissios, P.2
Kennedy, A.R.3
Koukos, G.4
Flier, J.S.5
Maratos-Flier, E.6
-
46
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
Kharitonenkov A., Shiyanova T.L., Koester A., Ford A.M., Micanovic R., Galbreath E.J., et al. FGF-21 as a novel metabolic regulator. The Journal of Clinical Investigation 2005, 115:1627-1635.
-
(2005)
The Journal of Clinical Investigation
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
-
47
-
-
69249093921
-
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity
-
Berglund E.D., Li C.Y., Bina H.A., Lynes S.E., Michael M.D., Shanafelt A.B., et al. Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity. Endocrinology 2009, 150:4084-4093.
-
(2009)
Endocrinology
, vol.150
, pp. 4084-4093
-
-
Berglund, E.D.1
Li, C.Y.2
Bina, H.A.3
Lynes, S.E.4
Michael, M.D.5
Shanafelt, A.B.6
-
48
-
-
57349098220
-
Fibroblast growth factor 21 corrects obesity in mice
-
Coskun T., Bina H.A., Schneider M.A., Dunbar J.D., Hu C.C., Chen Y., et al. Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 2008, 149:6018-6027.
-
(2008)
Endocrinology
, vol.149
, pp. 6018-6027
-
-
Coskun, T.1
Bina, H.A.2
Schneider, M.A.3
Dunbar, J.D.4
Hu, C.C.5
Chen, Y.6
-
49
-
-
84892721345
-
Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance inmice by inducing fibroblast growth factor 21
-
Li Y., Wong K., Giles A., Jiang J., Lee J.W., Adams A.C., et al. Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance inmice by inducing fibroblast growth factor 21. Gastroenterology 2014, 146:539-549.
-
(2014)
Gastroenterology
, vol.146
, pp. 539-549
-
-
Li, Y.1
Wong, K.2
Giles, A.3
Jiang, J.4
Lee, J.W.5
Adams, A.C.6
-
50
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
Xu J., Lloyd D.J., Hale C., Stanislaus S., Chen M., Sivits G., et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 2009, 58:250-259.
-
(2009)
Diabetes
, vol.58
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
Stanislaus, S.4
Chen, M.5
Sivits, G.6
-
51
-
-
20244380182
-
Angiopoietin-related growth factor antagonizes obesity and insulin resistance
-
Oike Y., Akao M., Yasunaga K., Yamauchi T., Morisada T., Ito Y., et al. Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nature Medicine 2005, 11:400-408.
-
(2005)
Nature Medicine
, vol.11
, pp. 400-408
-
-
Oike, Y.1
Akao, M.2
Yasunaga, K.3
Yamauchi, T.4
Morisada, T.5
Ito, Y.6
-
52
-
-
79960947880
-
Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?
-
Uebanso T., Taketani Y., Yamamoto H., Amo K., Ominami H., Arai H., et al. Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?. PloS One 2011, 6:e22976.
-
(2011)
PloS One
, vol.6
-
-
Uebanso, T.1
Taketani, Y.2
Yamamoto, H.3
Amo, K.4
Ominami, H.5
Arai, H.6
-
53
-
-
84876998618
-
Novel insights into ChREBP regulation and function
-
Filhoulaud G., Guilmeau S., Dentin R., Girard J., Postic C. Novel insights into ChREBP regulation and function. Trends in Endocrinology & Metabolism (TEM) 2013, 24:257-268.
-
(2013)
Trends in Endocrinology & Metabolism (TEM)
, vol.24
, pp. 257-268
-
-
Filhoulaud, G.1
Guilmeau, S.2
Dentin, R.3
Girard, J.4
Postic, C.5
-
54
-
-
83555160898
-
Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver
-
Dentin R., Tomas-Cobos L., Foufelle F., Leopold J., Girard J., Postic C., et al. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver. Journal of Hepatology 2012, 56:199-209.
-
(2012)
Journal of Hepatology
, vol.56
, pp. 199-209
-
-
Dentin, R.1
Tomas-Cobos, L.2
Foufelle, F.3
Leopold, J.4
Girard, J.5
Postic, C.6
-
55
-
-
84859921736
-
Anovel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
-
Herman M.A., Peroni O.D., Villoria J., Schön M.R., Abumrad N.A., Blüher M., et al. Anovel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 2012, 484:333-338.
-
(2012)
Nature
, vol.484
, pp. 333-338
-
-
Herman, M.A.1
Peroni, O.D.2
Villoria, J.3
Schön, M.R.4
Abumrad, N.A.5
Blüher, M.6
-
56
-
-
0346849699
-
The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells
-
Dressel U., Allen T.L., Pippal J.B., Rohde P.R., Lau P., Muscat G.E.O. The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Molecular Endocrinology 2003, 17:2477-2493.
-
(2003)
Molecular Endocrinology
, vol.17
, pp. 2477-2493
-
-
Dressel, U.1
Allen, T.L.2
Pippal, J.B.3
Rohde, P.R.4
Lau, P.5
Muscat, G.E.O.6
-
57
-
-
9144271149
-
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome
-
Tanaka T., Yamamoto J., Iwasaki S., Asaba H., Hamura H., Ikeda Y., et al. Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:15924-15929.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 15924-15929
-
-
Tanaka, T.1
Yamamoto, J.2
Iwasaki, S.3
Asaba, H.4
Hamura, H.5
Ikeda, Y.6
-
58
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
Wang Y.-X., Lee C.-H., Tiep S., Yu R.T., Ham J., Kang H., et al. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 2003, 113:159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.-X.1
Lee, C.-H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
-
60
-
-
44349161745
-
Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle
-
Taylor E.B., An D., Kramer H.F., Yu H., Fujii N.L., Roeckl K.S.C., et al. Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle. The Journal of Biological Chemistry 2008, 283:9787-9796.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 9787-9796
-
-
Taylor, E.B.1
An, D.2
Kramer, H.F.3
Yu, H.4
Fujii, N.L.5
Roeckl, K.S.C.6
-
61
-
-
0035798668
-
Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase
-
Xi X., Han J., Zhang J.Z. Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase. The Journal of Biological Chemistry 2001, 276:41029-41034.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 41029-41034
-
-
Xi, X.1
Han, J.2
Zhang, J.Z.3
-
62
-
-
0036097775
-
Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet
-
Mithieux G., Guignot L., Bordet J.-C., Wiernsperger N. Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet. Diabetes 2002, 51:139-143.
-
(2002)
Diabetes
, vol.51
, pp. 139-143
-
-
Mithieux, G.1
Guignot, L.2
Bordet, J.-C.3
Wiernsperger, N.4
-
63
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi N., Hirshman M.F., Nygren J., Svanfeldt M., Bavenholm P., Rooyackers O., et al. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 2002, 51:2074-2081.
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
-
64
-
-
84904312483
-
Metformin and the gut function
-
Transworld Research Network, Kerala, India
-
Mithieux G. Metformin and the gut function. Metformin mech. insights new appl. 2008, 31-40. Transworld Research Network, Kerala, India.
-
(2008)
Metformin mech. insights new appl.
, pp. 31-40
-
-
Mithieux, G.1
-
65
-
-
78649582182
-
Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1
-
Grefhorst A., Schreurs M., Oosterveer M.H., Cortés V.A., Havinga R., Herling A.W., et al. Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1. The Biochemical Journal 2010, 432:249-254.
-
(2010)
The Biochemical Journal
, vol.432
, pp. 249-254
-
-
Grefhorst, A.1
Schreurs, M.2
Oosterveer, M.H.3
Cortés, V.A.4
Havinga, R.5
Herling, A.W.6
-
67
-
-
84862025421
-
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
-
Sun Z., Miller R.A., Patel R.T., Chen J., Dhir R., Wang H., et al. Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nature Medicine 2012, 18:934-942.
-
(2012)
Nature Medicine
, vol.18
, pp. 934-942
-
-
Sun, Z.1
Miller, R.A.2
Patel, R.T.3
Chen, J.4
Dhir, R.5
Wang, H.6
-
68
-
-
84863012022
-
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
-
Fisher F.M., Kleiner S., Douris N., Fox E.C., Mepani R.J., Verdeguer F., et al. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes & Development 2012, 26:271-281.
-
(2012)
Genes & Development
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
-
69
-
-
80053428117
-
Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes
-
Ge X., Chen C., Hui X., Wang Y., Lam K.S.L., Xu A. Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes. The Journal of Biological Chemistry 2011, 286:34533-34541.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 34533-34541
-
-
Ge, X.1
Chen, C.2
Hui, X.3
Wang, Y.4
Lam, K.S.L.5
Xu, A.6
-
71
-
-
84883481988
-
The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes
-
Gaich G., Chien J.Y., Fu H., Glass L.C., Deeg M.A., Holland W.L., et al. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes. Cell Metabolism 2013, 18:333-340.
-
(2013)
Cell Metabolism
, vol.18
, pp. 333-340
-
-
Gaich, G.1
Chien, J.Y.2
Fu, H.3
Glass, L.C.4
Deeg, M.A.5
Holland, W.L.6
-
72
-
-
84880426480
-
Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody
-
Huang J., Ishino T., Chen G., Rolzin P., Osothprarop T.F., Retting K., et al. Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody. Journal of Pharmacology and Experimental Therapeutics 2013, 346:270-280.
-
(2013)
Journal of Pharmacology and Experimental Therapeutics
, vol.346
, pp. 270-280
-
-
Huang, J.1
Ishino, T.2
Chen, G.3
Rolzin, P.4
Osothprarop, T.F.5
Retting, K.6
-
73
-
-
85027936258
-
Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
-
Müller T.D., Sullivan L.M., Habegger K., Yi C.-X., Kabra D., Grant E., et al. Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21. Journal of Peptide Science: An Official Publication of the European Peptide Society 2012, 18:383-393.
-
(2012)
Journal of Peptide Science: An Official Publication of the European Peptide Society
, vol.18
, pp. 383-393
-
-
Müller, T.D.1
Sullivan, L.M.2
Habegger, K.3
Yi, C.-X.4
Kabra, D.5
Grant, E.6
-
74
-
-
84861890043
-
Outstanding scientific achievement award lecture 2011: defeating diabesity: the case for personalized combinatorial therapies
-
Tschöp M.H., DiMarchi R.D. Outstanding scientific achievement award lecture 2011: defeating diabesity: the case for personalized combinatorial therapies. Diabetes 2012, 61:1309-1314.
-
(2012)
Diabetes
, vol.61
, pp. 1309-1314
-
-
Tschöp, M.H.1
DiMarchi, R.D.2
|