Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas

Journal of Hepatology

Volumn 54, Issue 3, 2011, Pages 529-537

  Mutel, Elodie ^a,b,c   Abdul Wahed, Aya ^a,b,c   Ramamonjisoa, Nirilanto ^b,c,d   Stefanutti, Anne ^a,b,c   Houberdon, Isabelle ^a,b,c   Cavassila, Sophie ^b,c,d   Pilleul, Frank ^b,c,d   Beuf, Olivier ^b,c,d   Gautier Stein, Amandine ^a,b,c   Penhoat, Armelle ^a,b,c   Mithieux, Gilles ^a,b,c   Rajas, Fabienne ^a,b,c  

^a INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE   (France)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITÉ LYON 1   (France)

^d UNIVERSITÉ DE LYON   (France)

Author keywords

Endogenous glucose production; Glucose 6 phosphatase; Glycogen storage disease; Hepatic adenomas; Hepatic steatosis

Indexed keywords

GLUCOSE 6 PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY LIVER; GENE DELETION; GLUCOSE BLOOD LEVEL; GLYCOGEN STORAGE DISEASE; HEPATOMEGALY; HYPERLIPIDEMIA; IMMUNOHISTOCHEMISTRY; LACTIC ACIDOSIS; LIVER ADENOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMA, LIVER CELL; ANIMALS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; DNA PRIMERS; FATTY LIVER; FEMALE; GENE KNOCKOUT TECHNIQUES; GENE TARGETING; GLUCOSE-6-PHOSPHATASE; GLYCOGEN STORAGE DISEASE TYPE I; HEPATOMEGALY; HUMANS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 79951672283     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.08.014     Document Type: Article

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