Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: Insights in depression

Neuroscience

Volumn 275, Issue , 2014, Pages 455-468

  Ignacio Z M ^a,c   Reus G Z ^a,b   Abelaira, H M ^a   Quevedo, J ^a,b  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSIDADE FEDERAL DA FRONTEIRA SUL   (Brazil)

Author keywords

BDNF; Depression; Epigenetic; Lifelong stress; Polymorphism; Serotonin transporter

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLUOXETINE; GLUCOCORTICOID RECEPTOR; HISTONE DEACETYLASE; HYDROCORTISONE; MESSENGER RNA; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

AGITATION; AMINO ACID SUBSTITUTION; AMYGDALOID NUCLEUS; ANXIETY; BRAIN DERIVED NEUROTROPHIC FACTOR GENE; CHILD ABUSE; CPG ISLAND; DEPRESSION; DNA METHYLATION; DRUG WITHDRAWAL; EARLY LIFE STRESS; ENVIRONMENTAL FACTOR; EPIGENETICS; EPISTASIS; FATIGUE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HETEROZYGOTE; HIPPOCAMPUS; HISTONE ACETYLATION; HOMOZYGOTE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INSOMNIA; LIMBIC SYSTEM; MAJOR DEPRESSION; MENTAL STRESS; NONHUMAN; PHARMACOGENETICS; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; SEROTONIN TRANSPORTER GENE; SOCIAL SUPPORT; SUICIDE; UNSPECIFIED SIDE EFFECT; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSION; EPIGENESIS, GENETIC; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 84904249205     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.06.036     Document Type: Review

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