Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans

Neurobiology of Disease

Volumn 37, Issue 3, 2010, Pages 747-755

  Molteni, Raffaella ^a   Cattaneo, Annamaria ^b   Calabrese, Francesca ^a   Macchi, Flavia ^a   Olivier, Jocelien D A ^c   Racagni, Giorgio ^a,b   Ellenbroek, Bart A ^d   Gennarelli, Massimo ^b,e   Riva, Marco A ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d Evotec Technologies GmbH   (Germany)

^e UNIVERSITY OF BRESCIA   (Italy)

Author keywords

BDNF; Depression; Epigenetic mechanism; Gene expression; Mutant rat; SERT

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; SEROTONIN TRANSPORTER;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE PREDISPOSITION; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; EXON; GENE DELETION; GENE EXPRESSION; GENOTYPE; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; LEUKOCYTE; NONHUMAN; NORMAL HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROMOTER REGION; RAT;

ADULT; AGED; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; DOWN-REGULATION; EPIGENESIS, GENETIC; EXONS; FEMALE; GENE FREQUENCY; GENE KNOCKOUT TECHNIQUES; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOTYPE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RATS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 75949110071     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.12.014     Document Type: Article

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