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Volumn 14, Issue 3, 2014, Pages 241-258

Novel insights into the role of microRNA in lung cancer resistance to treatment and targeted therapy

Author keywords

Drug resistance; Metabolism; MicroRNA; Polymorphism; Targeted therapy

Indexed keywords

BIOLOGICAL MARKER; CELL NUCLEUS RECEPTOR; CISPLATIN; CYTOCHROME P450; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; MICRORNA; MICRORNA 1; MICRORNA 126; MICRORNA 130; MICRORNA 145; MICRORNA 155; MICRORNA 16; MICRORNA 17; MICRORNA 199; MICRORNA 205; MICRORNA 21; MICRORNA 221; MICRORNA 222; MICRORNA 29; MICRORNA 31; MICRORNA 34; MICRORNA 92; SUNITINIB; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANDETANIB; TUMOR MARKER;

EID: 84903714377     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/1568009614666140305104845     Document Type: Review
Times cited : (16)

References (166)
  • 3
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116 (2), 281-297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 84862211160 scopus 로고    scopus 로고
    • Role of microRNAs in lung cancer: MicroRNA signatures in cancer prognosis
    • Boeri, M.; Pastorino, U.; Sozzi, G. Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis. Cancer J. 2012, 18 (3), 268-274.
    • (2012) Cancer J , vol.18 , Issue.3 , pp. 268-274
    • Boeri, M.1    Pastorino, U.2    Sozzi, G.3
  • 7
    • 84865062501 scopus 로고    scopus 로고
    • Molecular pathways: MicroRNAs as cancer therapeutics
    • Melo, S.A.; Kalluri, R. Molecular pathways: microRNAs as cancer therapeutics. Clin. Cancer Res. 2012 18 (16), 4234-4239.
    • (2012) Clin. Cancer Res , vol.18 , Issue.16 , pp. 4234-4239
    • Melo, S.A.1    Kalluri, R.2
  • 12
    • 84876546221 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the role of microRNAs in resistance to epidermal growth factor receptor-targeted agents and novel therapeutic strategies for treatment of non-small-cell lung cancer
    • Maftouh, M.; Avan, A.; Galvani, E.; Peters, G.J.; Giovannetti, E. Molecular mechanisms underlying the role of microRNAs in resistance to epidermal growth factor receptor-targeted agents and novel therapeutic strategies for treatment of non-small-cell lung cancer. Crit. Rev. Oncog. 2013, 18 (4), 317-326.
    • (2013) Crit. Rev. Oncog , vol.18 , Issue.4 , pp. 317-326
    • Maftouh, M.1    Avan, A.2    Galvani, E.3    Peters, G.J.4    Giovannetti, E.5
  • 14
    • 0029759985 scopus 로고    scopus 로고
    • Molecular mechanisms of multidrug resistance in cancer chemotherapy
    • Nooter, K.; Stoter, G. Molecular mechanisms of multidrug resistance in cancer chemotherapy. Pathol Res. Pract. 1996, 192 (7), 768-780.
    • (1996) Pathol Res. Pract. , vol.192 , Issue.7 , pp. 768-780
    • Nooter, K.1    Stoter, G.2
  • 15
    • 0033799839 scopus 로고    scopus 로고
    • Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
    • Krishna, R.; Mayer, L.D. Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur. J. Pharm. Sci. 2000, 11 (4), 265-283.
    • (2000) Eur. J. Pharm. Sci , vol.11 , Issue.4 , pp. 265-283
    • Krishna, R.1    Mayer, L.D.2
  • 16
    • 73449126570 scopus 로고    scopus 로고
    • Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review
    • Liu, F.S. Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review. Taiwan J. Obstet. Gynecol. 2009, 48 (3), 239-244.
    • (2009) Taiwan J. Obstet. Gynecol , vol.48 , Issue.3 , pp. 239-244
    • Liu, F.S.1
  • 17
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman, M.M. Mechanisms of cancer drug resistance. Annu. Rev. Med. 2002, 53, 615-627.
    • (2002) Annu. Rev. Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 19
    • 0642374221 scopus 로고    scopus 로고
    • The role of glutathione-S-transferase in anti-cancer drug resistance
    • Townsend, D.M.; Tew, K.D. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 2003, 22 (47), 7369-7375.
    • (2003) Oncogene , vol.22 , Issue.47 , pp. 7369-7375
    • Townsend, D.M.1    Tew, K.D.2
  • 20
    • 0023718434 scopus 로고
    • Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II)
    • Eastman, A.; Schulte, N. Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II). Biochemistry 1988, 27 (13), 4730-4734.
    • (1988) Biochemistry , vol.27 , Issue.13 , pp. 4730-4734
    • Eastman, A.1    Schulte, N.2
  • 21
    • 0030931827 scopus 로고    scopus 로고
    • Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific betatubulin isotypes
    • Kavallaris, M.; Kuo, D.Y.; Burkhart, C.A.; Regl, D.L.; Norris, M.D.; Haber, M.; Horwitz, S.B. Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific betatubulin isotypes. J. Clin. Invest. 1997, 100 (5), 1282-1293.
    • (1997) J. Clin. Invest , vol.100 , Issue.5 , pp. 1282-1293
    • Kavallaris, M.1    Kuo, D.Y.2    Burkhart, C.A.3    Regl, D.L.4    Norris, M.D.5    Haber, M.6    Horwitz, S.B.7
  • 22
    • 0033032317 scopus 로고    scopus 로고
    • Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
    • Sethi, T.; Rintoul, R.C.; Moore, S.M.; MacKinnon, A.C.; Salter, D.; Choo, C.; Chilvers, E.R.; Dransfield, I.; Donnelly, S.C.; Strieter, R.; Haslett, C. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat. Med. 1999, 5 (6), 662-668.
    • (1999) Nat. Med , vol.5 , Issue.6 , pp. 662-668
    • Sethi, T.1    Rintoul, R.C.2    Moore, S.M.3    Mackinnon, A.C.4    Salter, D.5    Choo, C.6    Chilvers, E.R.7    Dransfield, I.8    Donnelly, S.C.9    Strieter, R.10    Haslett, C.11
  • 23
    • 0141520276 scopus 로고    scopus 로고
    • Drug resistance and the microenvironment: Nature and nurture
    • Morin, P.J. Drug resistance and the microenvironment: nature and nurture. Drug Resist. Updat. 2003, 6 (4), 169-172.
    • (2003) Drug Resist. Updat , vol.6 , Issue.4 , pp. 169-172
    • Morin, P.J.1
  • 24
    • 0033012394 scopus 로고    scopus 로고
    • Adhesion-dependent multicellular drug resistance
    • Green, S.K.; Frankel, A.; Kerbel, R.S. Adhesion-dependent multicellular drug resistance. Anticancer Drug Des. 1999, 14 (2), 153-168.
    • (1999) Anticancer Drug Des , vol.14 , Issue.2 , pp. 153-168
    • Green, S.K.1    Frankel, A.2    Kerbel, R.S.3
  • 30
    • 84863229381 scopus 로고    scopus 로고
    • MiRNA-21: A biomarker predictive for platinum-based adjuvant chemotherapy response in patients with non-small cell lung cancer
    • Gao, W.; Lu, X.; Liu, L.; Xu, J.; Feng, D.; Shu, Y. MiRNA-21: a biomarker predictive for platinum-based adjuvant chemotherapy response in patients with non-small cell lung cancer. Cancer Biol. Ther. 2012, 13 (5), 330-340.
    • (2012) Cancer Biol. Ther , vol.13 , Issue.5 , pp. 330-340
    • Gao, W.1    Lu, X.2    Liu, L.3    Xu, J.4    Feng, D.5    Shu, Y.6
  • 33
    • 77956921020 scopus 로고    scopus 로고
    • MicroRNA-21: From cancer to cardiovascular disease
    • Jazbutyte, V.; Thum, T. MicroRNA-21: from cancer to cardiovascular disease. Curr. Drug Targets 2010, 11 (8), 926-935.
    • (2010) Curr. Drug Targets , vol.11 , Issue.8 , pp. 926-935
    • Jazbutyte, V.1    Thum, T.2
  • 34
    • 84866743135 scopus 로고    scopus 로고
    • miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer
    • Zhong, Z.; Dong, Z.; Yang, L.; Gong, Z. miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer. J. Cancer Res. Clin. Oncol. 2012, 138 (10), 1781-1788.
    • (2012) J. Cancer Res. Clin. Oncol , vol.138 , Issue.10 , pp. 1781-1788
    • Zhong, Z.1    Dong, Z.2    Yang, L.3    Gong, Z.4
  • 35
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • Zhang, J.G.; Wang, J.J.; Zhao, F.; Liu, Q.; Jiang, K.; Yang, G.H. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin. Chim. Acta 2010, 411 (11-12), 846-852.
    • (2010) Clin. Chim. Acta , vol.411 , Issue.11-12 , pp. 846-852
    • Zhang, J.G.1    Wang, J.J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5    Yang, G.H.6
  • 37
    • 54049115558 scopus 로고    scopus 로고
    • Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR
    • Markou, A.; Tsaroucha, E.G.; Kaklamanis, L.; Fotinou, M.; Georgoulias, V.; Lianidou, E.S. Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR. Clin. Chem. 2008, 54 (10), 1696-1704.
    • (2008) Clin. Chem , vol.54 , Issue.10 , pp. 1696-1704
    • Markou, A.1    Tsaroucha, E.G.2    Kaklamanis, L.3    Fotinou, M.4    Georgoulias, V.5    Lianidou, E.S.6
  • 39
    • 47549109566 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • Lu, Z.; Liu, M.; Stribinskis, V.; Klinge, C.M.; Ramos, K.S.; Colburn, N.H.; Li, Y. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008, 27 (31), 4373-4379.
    • (2008) Oncogene , vol.27 , Issue.31 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3    Klinge, C.M.4    Ramos, K.S.5    Colburn, N.H.6    Li, Y.7
  • 42
    • 59649105246 scopus 로고    scopus 로고
    • MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis
    • Navarro, A.; Marrades, R.M.; Viñolas, N.; Quera, A.; Agustí, C.; Huerta, A.; Ramirez, J.; Torres, A.; Monzo, M. MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis. Oncology 2009, 76 (3), 162-169.
    • (2009) Oncology , vol.76 , Issue.3 , pp. 162-169
    • Navarro, A.1    Marrades, R.M.2    Viñolas, N.3    Quera, A.4    Agustí, C.5    Huerta, A.6    Ramirez, J.7    Torres, A.8    Monzo, M.9
  • 44
    • 77951026718 scopus 로고    scopus 로고
    • MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene
    • Jiang, S.; Zhang, H.W.; Lu, M.H.; He, X.H.; Li, Y.; Gu, H.; Liu, M.F.; Wang, E.D. MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Cancer Res. 2010, 70 (8), 3119-3127.
    • (2010) Cancer Res , vol.70 , Issue.8 , pp. 3119-3127
    • Jiang, S.1    Zhang, H.W.2    Lu, M.H.3    He, X.H.4    Li, Y.5    Gu, H.6    Liu, M.F.7    Wang, E.D.8
  • 47
    • 70349464806 scopus 로고    scopus 로고
    • Takahashi, T.Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers
    • Ebi, H.; Sato, T.; Sugito, N.; Hosono, Y.; Yatabe, Y.; Matsuyama, Y.; Yamaguchi, T.; Osada, H.; Suzuki, M.; Takahashi, T.Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers. Oncogene 2009, 28 (38), 3371-3379.
    • (2009) Oncogene , vol.28 , Issue.38 , pp. 3371-3379
    • Ebi, H.1    Sato, T.2    Sugito, N.3    Hosono, Y.4    Yatabe, Y.5    Matsuyama, Y.6    Yamaguchi, T.7    Osada, H.8    Suzuki, M.9
  • 49
    • 84878685640 scopus 로고    scopus 로고
    • MicroRNA-31- 5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells
    • Zhong, Z.; Dong, Z.; Yang, L.; Chen, X.; Gong, Z. MicroRNA-31- 5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells. Tumour Biol. 2013, 34 (3), 1959-1965.
    • (2013) Tumour Biol , vol.34 , Issue.3 , pp. 1959-1965
    • Zhong, Z.1    Dong, Z.2    Yang, L.3    Chen, X.4    Gong, Z.5
  • 50
    • 84891829677 scopus 로고    scopus 로고
    • MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9
    • Dong, Z.; Zhong, Z.; Yang, L.; Wang, S.; Gong, Z. MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9. Cancer Lett. 2014, 343 (2), 249-257.
    • (2014) Cancer Lett , vol.343 , Issue.2 , pp. 249-257
    • Dong, Z.1    Zhong, Z.2    Yang, L.3    Wang, S.4    Gong, Z.5
  • 51
    • 67651002796 scopus 로고    scopus 로고
    • MicroRNA classifiers for predicting prognosis of squamous cell lung cancer
    • Raponi, M.; Dossey, L.; Jatkoe, T.; Wu, X.; Chen, G.; Fan, H.; Beer, D.G. MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res. 2009, 69 (14), 5776-5783.
    • (2009) Cancer Res , vol.69 , Issue.14 , pp. 5776-5783
    • Raponi, M.1    Dossey, L.2    Jatkoe, T.3    Wu, X.4    Chen, G.5    Fan, H.6    Beer, D.G.7
  • 52
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee, Y.S.; Dutta, A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 2007, 21 (9), 1025-1030.
    • (2007) Genes Dev , vol.21 , Issue.9 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 55
    • 55549127406 scopus 로고    scopus 로고
    • Let-7 regulates Dicer expression and constitutes a negative feedback loop
    • Tokumaru, S.; Suzuki, M.; Yamada, H.; Nagino, M.; Takahashi, T. let-7 regulates Dicer expression and constitutes a negative feedback loop. Carcinogenesis 2008, 29 (11), 2073-2077.
    • (2008) Carcinogenesis , vol.29 , Issue.11 , pp. 2073-2077
    • Tokumaru, S.1    Suzuki, M.2    Yamada, H.3    Nagino, M.4    Takahashi, T.5
  • 60
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1- arrest
    • Tarasov, V.; Jung, P.; Verdoodt, B.; Lodygin, D.; Epanchintsev, A.; Menssen, A.; Meister, G.; Hermeking, H. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1- arrest. Cell Cycle 2007, 6 (13), 1586-1593.
    • (2007) Cell Cycle , vol.6 , Issue.13 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 62
    • 79959673368 scopus 로고    scopus 로고
    • Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer
    • Mudduluru, G.; Ceppi, P.; Kumarswamy, R.; Scagliotti, G.V.; Papotti, M.; Allgayer, H. Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer. Oncogene 2011, 30 (25), 2888-2899.
    • (2011) Oncogene , vol.30 , Issue.25 , pp. 2888-2899
    • Mudduluru, G.1    Ceppi, P.2    Kumarswamy, R.3    Scagliotti, G.V.4    Papotti, M.5    Allgayer, H.6
  • 65
    • 67650422613 scopus 로고    scopus 로고
    • miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer
    • Bandi, N.; Zbinden, S.; Gugger, M.; Arnold, M.; Kocher, V.; Hasan, L.; Kappeler, A.; Brunner, T.; Vassella, E. miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer Res. 2009, 69 (13), 5553-5559.
    • (2009) Cancer Res , vol.69 , Issue.13 , pp. 5553-5559
    • Bandi, N.1    Zbinden, S.2    Gugger, M.3    Arnold, M.4    Kocher, V.5    Hasan, L.6    Kappeler, A.7    Brunner, T.8    Vassella, E.9
  • 66
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
    • Nasser, M.W.; Datta, J.; Nuovo, G.; Kutay, H.; Motiwala, T.; Majumder, S.; Wang, B.; Suster, S.; Jacob, S.T.; Ghoshal, K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J. Biol. Chem. 2008, 283 (48), 33394-33405.
    • (2008) J. Biol. Chem , vol.283 , Issue.48 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3    Kutay, H.4    Motiwala, T.5    Majumder, S.6    Wang, B.7    Suster, S.8    Jacob, S.T.9    Ghoshal, K.10
  • 67
    • 77958193337 scopus 로고    scopus 로고
    • National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): Design, intent, and availability of specimens for validation of lung cancer biomarkers
    • Patz, E.F. Jr.; Caporaso, N.E.; Dubinett, S.M.; Massion, P.P.; Hirsch, F.R.; Minna, J.D.; Gatsonis, C.; Duan, F.; Adams, A.; Apgar, C.; Medina, R.M.; Aberle, D.R. National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers. J. Thorac. Oncol. 2010, 5 (10), 1502-1506.
    • (2010) J. Thorac. Oncol , vol.5 , Issue.10 , pp. 1502-1506
    • Patz Jr., E.F.1    Caporaso, N.E.2    Dubinett, S.M.3    Massion, P.P.4    Hirsch, F.R.5    Minna, J.D.6    Gatsonis, C.7    Duan, F.8    Adams, A.9    Apgar, C.10    Medina, R.M.11    Aberle, D.R.12
  • 69
    • 67650520139 scopus 로고    scopus 로고
    • Detection of cancer with serum miRNAs on an oligonucleotide microarray
    • Lodes, M.J.; Caraballo, M.; Suciu, D.; Munro, S.; Kumar, A.; Anderson, B. Detection of cancer with serum miRNAs on an oligonucleotide microarray. PLoS One 2009, 4 (7), e6229.
    • (2009) PLoS One , vol.4 , Issue.7
    • Lodes, M.J.1    Caraballo, M.2    Suciu, D.3    Munro, S.4    Kumar, A.5    Anderson, B.6
  • 70
    • 79957452077 scopus 로고    scopus 로고
    • Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer
    • Roth, C.; Kasimir-Bauer, S.; Pantel, K.; Schwarzenbach, H. Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer. Mol. Oncol. 2011, 5 (3), 281-291.
    • (2011) Mol. Oncol , vol.5 , Issue.3 , pp. 281-291
    • Roth, C.1    Kasimir-Bauer, S.2    Pantel, K.3    Schwarzenbach, H.4
  • 74
    • 48649100900 scopus 로고    scopus 로고
    • The genomic analysis of erythrocyte microRNA expression in sickle cell diseases
    • Chen, S.Y.; Wang, Y.; Telen, M.J.; Chi, J.T. The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. PLoS One 2008, 3 (6), e2360.
    • (2008) PLoS One , vol.3 , Issue.6
    • Chen, S.Y.1    Wang, Y.2    Telen, M.J.3    Chi, J.T.4
  • 76
    • 77955175327 scopus 로고    scopus 로고
    • Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers
    • Xing, L.; Todd, N.W.; Yu, L.; Fang, H.; Jiang, F. Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers. Mod. Pathol. 2010, 23 (8), 1157-1164.
    • (2010) Mod. Pathol , vol.23 , Issue.8 , pp. 1157-1164
    • Xing, L.1    Todd, N.W.2    Yu, L.3    Fang, H.4    Jiang, F.5
  • 80
    • 75149130928 scopus 로고    scopus 로고
    • Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection
    • Patnaik, S.K.; Kannisto, E.; Knudsen, S.; Yendamuri, S. Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection. Cancer Res. 2010, 70 (1), 36-45.
    • (2010) Cancer Res , vol.70 , Issue.1 , pp. 36-45
    • Patnaik, S.K.1    Kannisto, E.2    Knudsen, S.3    Yendamuri, S.4
  • 82
    • 77954315239 scopus 로고    scopus 로고
    • Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    • Gao, W.; Yu, Y.; Cao, H.; Shen, H.; Li, X.; Pan, S.; Shu, Y. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed. Pharmacother. 2010, 64 (6), 399-408.
    • (2010) Biomed. Pharmacother , vol.64 , Issue.6 , pp. 399-408
    • Gao, W.1    Yu, Y.2    Cao, H.3    Shen, H.4    Li, X.5    Pan, S.6    Shu, Y.7
  • 83
    • 77950498821 scopus 로고    scopus 로고
    • Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
    • Hu, Z.; Chen, X.; Zhao, Y.; Tian, T.; Jin, G.; Shu, Y.; Chen, Y.; Xu, L.; Zen, K.; Zhang, C.; Shen, H. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J. Clin. Oncol. 2010, 28 (10), 1721-1726.
    • (2010) J. Clin. Oncol , vol.28 , Issue.10 , pp. 1721-1726
    • Hu, Z.1    Chen, X.2    Zhao, Y.3    Tian, T.4    Jin, G.5    Shu, Y.6    Chen, Y.7    Xu, L.8    Zen, K.9    Zhang, C.10    Shen, H.11
  • 86
    • 55849092497 scopus 로고    scopus 로고
    • Inhibitory effects of antimiRNA oligonucleotides (AMOs) on A549 cell growth
    • Fei, J.; Lan, F.; Guo, M.; Li, Y.; Liu, Y. Inhibitory effects of antimiRNA oligonucleotides (AMOs) on A549 cell growth. J. Drug Target 2008, 16 (9), 688-693.
    • (2008) J. Drug Target , vol.16 , Issue.9 , pp. 688-693
    • Fei, J.1    Lan, F.2    Guo, M.3    Li, Y.4    Liu, Y.5
  • 88
    • 34047270440 scopus 로고    scopus 로고
    • Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    • Gaur, A.; Jewell, D.A.; Liang, Y.; Ridzon, D.; Moore, J.H.; Chen, C.; Ambros, V.R.; Israel, M.A. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res. 2007, 67 (6), 2456-2468.
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2456-2468
    • Gaur, A.1    Jewell, D.A.2    Liang, Y.3    Ridzon, D.4    Moore, J.H.5    Chen, C.6    Ambros, V.R.7    Israel, M.A.8
  • 90
    • 77952944048 scopus 로고    scopus 로고
    • MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
    • Kong, W.; He, L.; Coppola, M.; Guo, J.; Esposito, N.N.; Coppola, D.; Cheng, J.Q. MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J. Biol. Chem. 2010, 285 (23), 17869-17879.
    • (2010) J. Biol. Chem , vol.285 , Issue.23 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3    Guo, J.4    Esposito, N.N.5    Coppola, D.6    Cheng, J.Q.7
  • 92
    • 77958607336 scopus 로고    scopus 로고
    • Cell-free miRNAs may indicate diagnosis and docetaxel sensitivity of tumor cells in malignant effusions
    • Xie, L.; Chen, X.; Wang, L.; Qian, X.; Wang, T.; Wei, J.; Yu, L.; Ding, Y.; Zhang, C.; Liu, B. Cell-free miRNAs may indicate diagnosis and docetaxel sensitivity of tumor cells in malignant effusions. BMC Cancer 2010, 10, 591.
    • (2010) BMC Cancer , vol.10 , pp. 591
    • Xie, L.1    Chen, X.2    Wang, L.3    Qian, X.4    Wang, T.5    Wei, J.6    Yu, L.7    Ding, Y.8    Zhang, C.9    Liu, B.10
  • 93
    • 77949773251 scopus 로고    scopus 로고
    • MicroRNAs contribute to the chemoresistance of cisplatin in tongue squamous cell carcinoma lines
    • Yu, Z.W.; Zhong, L.P.; Ji, T.; Zhang, P.; Chen, W.T.; Zhang, C.P. MicroRNAs contribute to the chemoresistance of cisplatin in tongue squamous cell carcinoma lines. Oral Oncol. 2010, 46 (4), 317-322.
    • (2010) Oral Oncol , vol.46 , Issue.4 , pp. 317-322
    • Yu, Z.W.1    Zhong, L.P.2    Ji, T.3    Zhang, P.4    Chen, W.T.5    Zhang, C.P.6
  • 94
    • 77955093873 scopus 로고    scopus 로고
    • MicroRNA 92a-2*: A biomarker predictive for chemoresistance and prognostic for survival in patients with small cell lung cancer
    • Ranade, A.R.; Cherba, D.; Sridhar, S.; Richardson, P.; Webb, C.; Paripati, A.; Bowles, B.; Weiss, G.J. MicroRNA 92a-2*: a biomarker predictive for chemoresistance and prognostic for survival in patients with small cell lung cancer. J. Thorac. Oncol. 2010, 5 (8), 1273-1278.
    • (2010) J. Thorac. Oncol , vol.5 , Issue.8 , pp. 1273-1278
    • Ranade, A.R.1    Cherba, D.2    Sridhar, S.3    Richardson, P.4    Webb, C.5    Paripati, A.6    Bowles, B.7    Weiss, G.J.8
  • 96
    • 65649138698 scopus 로고    scopus 로고
    • MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and individualized medicine
    • Mishra, P.J.; Bertino, J.R. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics 2009, 10 (3), 399-416.
    • (2009) Pharmacogenomics , vol.10 , Issue.3 , pp. 399-416
    • Mishra, P.J.1    Bertino, J.R.2
  • 97
    • 37749027621 scopus 로고    scopus 로고
    • Pharmacogenomics of microRNA: A miRSNP towards individualized therapy
    • Bertino, J.R.; Banerjee, D.; Mishra, P.J. Pharmacogenomics of microRNA: a miRSNP towards individualized therapy. Pharmacogenomics 2007, 8 (12), 1625-1627.
    • (2007) Pharmacogenomics , vol.8 , Issue.12 , pp. 1625-1627
    • Bertino, J.R.1    Banerjee, D.2    Mishra, P.J.3
  • 98
    • 42449110323 scopus 로고    scopus 로고
    • MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics
    • Mishra, P.J.; Mishra, P.J.; Banerjee, D.; Bertino, J.R. MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics. Cell Cycle 2008, 7 (7), 853-858.
    • (2008) Cell Cycle , vol.7 , Issue.7 , pp. 853-858
    • Mishra, P.J.1    Mishra, P.J.2    Banerjee, D.3    Bertino, J.R.4
  • 100
    • 74949118645 scopus 로고    scopus 로고
    • Expression of MRP1, BCRP, LRP, and ERCC1 in advanced non-small-cell lung cancer: Correlation with response to chemotherapy and survival
    • Li, J.; Li, Z.N.; Du, Y.J.; Li, X.Q.; Bao, Q.L.; Chen, P. Expression of MRP1, BCRP, LRP, and ERCC1 in advanced non-small-cell lung cancer: correlation with response to chemotherapy and survival. Clin. Lung Cancer 2009, 10 (6), 414-421.
    • (2009) Clin. Lung Cancer , vol.10 , Issue.6 , pp. 414-421
    • Li, J.1    Li, Z.N.2    Du, Y.J.3    Li, X.Q.4    Bao, Q.L.5    Chen, P.6
  • 101
    • 69949162040 scopus 로고    scopus 로고
    • Gene polymorphisms and chemotherapy in non-small cell lung cancer
    • Osawa, K. Gene polymorphisms and chemotherapy in non-small cell lung cancer. Zhongguo Fei Ai Za Zhi 2009, 12 (8), 837-840.
    • (2009) Zhongguo Fei Ai Za Zhi , vol.12 , Issue.8 , pp. 837-840
    • Osawa, K.1
  • 102
    • 33845399708 scopus 로고    scopus 로고
    • Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing
    • Narvaiza, I.; Aparicio, O.; Vera, M.; Razquin, N.; Bortolanza, S.; Prieto, J.; Fortes, P. Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing. J. Virol. 2006, 80 (24), 12236-12247.
    • (2006) J. Virol , vol.80 , Issue.24 , pp. 12236-12247
    • Narvaiza, I.1    Aparicio, O.2    Vera, M.3    Razquin, N.4    Bortolanza, S.5    Prieto, J.6    Fortes, P.7
  • 103
    • 49149114863 scopus 로고    scopus 로고
    • Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
    • Zhu, H.; Wu, H.; Liu, X.; Evans, B.R.; Medina, D.J.; Liu, C.G.; Yang, J.M. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem. Pharmacol. 2008, 76 (5), 582-588.
    • (2008) Biochem. Pharmacol , vol.76 , Issue.5 , pp. 582-588
    • Zhu, H.1    Wu, H.2    Liu, X.3    Evans, B.R.4    Medina, D.J.5    Liu, C.G.6    Yang, J.M.7
  • 104
    • 50249188925 scopus 로고    scopus 로고
    • Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line
    • To, K.K.; Zhan, Z.; Litman, T.; Bates, S.E. Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line. Mol. Cell Biol. 2008, 28 (17), 5147-5161.
    • (2008) Mol. Cell Biol , vol.28 , Issue.17 , pp. 5147-5161
    • To, K.K.1    Zhan, Z.2    Litman, T.3    Bates, S.E.4
  • 105
    • 66849113786 scopus 로고    scopus 로고
    • MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
    • Pan, Y.Z.; Morris, M.E.; Yu, A.M. MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. Mol. Pharmacol. 2009, 75 (6), 1374-1379.
    • (2009) Mol. Pharmacol , vol.75 , Issue.6 , pp. 1374-1379
    • Pan, Y.Z.1    Morris, M.E.2    Yu, A.M.3
  • 106
    • 44349182094 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4
    • Takagi, S.; Nakajima, M.; Mohri, T.; Yokoi, T. Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4. J. Biol. Chem. 2008, 283 (15), 9674-9680.
    • (2008) J. Biol. Chem , vol.283 , Issue.15 , pp. 9674-9680
    • Takagi, S.1    Nakajima, M.2    Mohri, T.3    Yokoi, T.4
  • 107
    • 33749487425 scopus 로고    scopus 로고
    • MicroRNA regulates the expression of human cytochrome P450 1B1
    • Tsuchiya, Y.; Nakajima, M.; Takagi, S.; Taniya, T.; Yokoi, T. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res. 2006, 66 (18), 9090-9098.
    • (2006) Cancer Res , vol.66 , Issue.18 , pp. 9090-9098
    • Tsuchiya, Y.1    Nakajima, M.2    Takagi, S.3    Taniya, T.4    Yokoi, T.5
  • 108
    • 35348908290 scopus 로고    scopus 로고
    • Small interfering RNA in drug metabolism and transport
    • Yu, AM. Small interfering RNA in drug metabolism and transport. Curr. Drug Metab. 2007, 8 (7), 700-708.
    • (2007) Curr. Drug Metab , vol.8 , Issue.7 , pp. 700-708
    • Yu, A.M.1
  • 109
    • 33751520430 scopus 로고    scopus 로고
    • Natural selection on human microRNA binding sites inferred from SNP data
    • Chen, K.; Rajewsky, N. Natural selection on human microRNA binding sites inferred from SNP data. Nat. Genet. 2006, 38 (12), 1452-1456.
    • (2006) Nat. Genet. , vol.38 , Issue.12 , pp. 1452-1456
    • Chen, K.1    Rajewsky, N.2
  • 110
    • 33847665108 scopus 로고    scopus 로고
    • Human polymorphism at microRNAs and microRNA target sites
    • Saunders, M.A.; Liang, H.; Li, W.H. Human polymorphism at microRNAs and microRNA target sites. Proc. Natl. Acad. Sci. U. S. A. 2007, 104 (9), 3300-3305.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.104 , Issue.9 , pp. 3300-3305
    • Saunders, M.A.1    Liang, H.2    Li, W.H.3
  • 111
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • Kertesz, M.; Iovino, N.; Unnerstall, U.; Gaul, U.; Segal, E. The role of site accessibility in microRNA target recognition. Nat. Genet. 2007, 39 (10), 1278-1284.
    • (2007) Nat. Genet , vol.39 , Issue.10 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3    Gaul, U.4    Segal, E.5
  • 112
    • 34748927204 scopus 로고    scopus 로고
    • The micro RNA target paradigm: A fundamental and polymorphic control layer of cellular expression
    • Barnes, M.R.; Deharo, S.; Grocock, R.J.; Brown, J.R.; Sanseau, P. The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression. Expert Opin. Biol.Ther. 2007, 7 (9), 1387-1399.
    • (2007) Expert Opin. Biol.Ther , vol.7 , Issue.9 , pp. 1387-1399
    • Barnes, M.R.1    Deharo, S.2    Grocock, R.J.3    Brown, J.R.4    Sanseau, P.5
  • 114
    • 67650365554 scopus 로고    scopus 로고
    • Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation
    • Cho, W.C.; Chow, A.S.; Au, J.S. Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur. J. Cancer 2009, 45 (12), 2197-2206.
    • (2009) Eur. J. Cancer , vol.45 , Issue.12 , pp. 2197-2206
    • Cho, W.C.1    Chow, A.S.2    Au, J.S.3
  • 117
    • 84855359334 scopus 로고    scopus 로고
    • A microRNA gene expression signature predicts response to erlotinib in epithelial cancer cell lines and targets EMT
    • Bryant, J.L.; Britson, J.; Balko, J.M.; Willian, M.; Timmons, R.; Frolov, A.; Black, E.P. A microRNA gene expression signature predicts response to erlotinib in epithelial cancer cell lines and targets EMT. Br. J. Cancer 2012, 106 (1), 148-156.
    • (2012) Br. J. Cancer , vol.106 , Issue.1 , pp. 148-156
    • Bryant, J.L.1    Britson, J.2    Balko, J.M.3    Willian, M.4    Timmons, R.5    Frolov, A.6    Black, E.P.7
  • 118
    • 84864865233 scopus 로고    scopus 로고
    • MicroRNA-214 regulates the acquired resistance to gefitinib via the PTEN/AKT pathway in EGFR-mutant cell lines
    • Wang, Y.S.; Wang, Y.H.; Xia, H.P.; Zhou, S.W.; Schmid-Bindert, G.; Zhou, C.C. MicroRNA-214 regulates the acquired resistance to gefitinib via the PTEN/AKT pathway in EGFR-mutant cell lines. Asian Pac. J. Cancer Prev. 2012, 13 (1), 255-260.
    • (2012) Asian Pac. J. Cancer Prev , vol.13 , Issue.1 , pp. 255-260
    • Wang, Y.S.1    Wang, Y.H.2    Xia, H.P.3    Zhou, S.W.4    Schmid-Bindert, G.5    Zhou, C.C.6
  • 119
    • 80052698948 scopus 로고    scopus 로고
    • Liposomal delivery of MicroRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells
    • Rai, K.; Takigawa, N.; Ito, S.; Kashihara, H.; Ichihara, E.; Yasuda, T.; Shimizu, K.; Tanimoto, M.; Kiura, K. Liposomal delivery of MicroRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells. Mol. Cancer Ther. 2011, 10 (9), 1720-1727.
    • (2011) Mol. Cancer Ther , vol.10 , Issue.9 , pp. 1720-1727
    • Rai, K.1    Takigawa, N.2    Ito, S.3    Kashihara, H.4    Ichihara, E.5    Yasuda, T.6    Shimizu, K.7    Tanimoto, M.8    Kiura, K.9
  • 121
    • 34547819299 scopus 로고    scopus 로고
    • The promise of TRAIL-- potential and risks of a novel anticancer therapy
    • Koschny, R.; Walczak, H.; Ganten, T.M. The promise of TRAIL-- potential and risks of a novel anticancer therapy. J. Mol. Med. (Berl). 2007, 85 (9), 923-935.
    • (2007) J. Mol. Med. (Berl) , vol.85 , Issue.9 , pp. 923-935
    • Koschny, R.1    Walczak, H.2    Ganten, T.M.3
  • 123
    • 77951716642 scopus 로고    scopus 로고
    • miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED
    • Incoronato, M.; Garofalo, M.; Urso, L.; Romano, G.; Quintavalle, C.; Zanca, C.; Iaboni, M.; Nuovo, G.; Croce, C.M.; Condorelli, G. miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED. Cancer Res. 2010, 70 (9), 3638-3646.
    • (2010) Cancer Res , vol.70 , Issue.9 , pp. 3638-3646
    • Incoronato, M.1    Garofalo, M.2    Urso, L.3    Romano, G.4    Quintavalle, C.5    Zanca, C.6    Iaboni, M.7    Nuovo, G.8    Croce, C.M.9    Condorelli, G.10
  • 124
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • Garzon, R.; Marcucci, G.; Croce, C.M. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug Discov. 2010, 9 (10), 775-789.
    • (2010) Nat. Rev. Drug Discov , vol.9 , Issue.10 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 126
    • 84869120708 scopus 로고    scopus 로고
    • Discovering the first microRNAtargeted drug
    • Lindow, M.; Kauppinen, S. Discovering the first microRNAtargeted drug. J. Cell Biol. 2012, 199 (3), 407-412.
    • (2012) J. Cell Biol , vol.199 , Issue.3 , pp. 407-412
    • Lindow, M.1    Kauppinen, S.2
  • 127
    • 84871225984 scopus 로고    scopus 로고
    • TLRs as miRNA receptors
    • Fabbri, M. TLRs as miRNA receptors. Cancer Res. 2012, 72 (24), 6333-6337.
    • (2012) Cancer Res , vol.72 , Issue.24 , pp. 6333-6337
    • Fabbri, M.1
  • 128
    • 78650491562 scopus 로고    scopus 로고
    • Resistance may not be futile: MicroRNA biomarkers for chemoresistance and potential therapeutics
    • Allen, K.E.; Weiss, G.J. Resistance may not be futile: microRNA biomarkers for chemoresistance and potential therapeutics. Mol. Cancer Ther. 2010, 9 (12), 3126-3136.
    • (2010) Mol. Cancer Ther , vol.9 , Issue.12 , pp. 3126-3136
    • Allen, K.E.1    Weiss, G.J.2
  • 131
    • 79957900919 scopus 로고    scopus 로고
    • Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
    • Trang, P.; Wiggins, J.F.; Daige, C.L.; Cho, C.; Omotola, M.; Brown, D.; Weidhaas, J.B.; Bader, A.G.; Slack, F.J. Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther. 2011, 19 (6), 1116-1122.
    • (2011) Mol Ther , vol.19 , Issue.6 , pp. 1116-1122
    • Trang, P.1    Wiggins, J.F.2    Daige, C.L.3    Cho, C.4    Omotola, M.5    Brown, D.6    Weidhaas, J.B.7    Bader, A.G.8    Slack, F.J.9
  • 133
    • 77955022405 scopus 로고    scopus 로고
    • Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
    • Wiggins, J.F.; Ruffino, L.; Kelnar, K.; Omotola, M.; Patrawala, L.; Brown, D.; Bader, A.G. Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 2010, 70 (14), 5923-5930.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5923-5930
    • Wiggins, J.F.1    Ruffino, L.2    Kelnar, K.3    Omotola, M.4    Patrawala, L.5    Brown, D.6    Bader, A.G.7
  • 134
    • 70350596499 scopus 로고    scopus 로고
    • MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines
    • Muniyappa, M.K.; Dowling, P.; Henry, M.; Meleady, P.; Doolan, P.; Gammell, P.; Clynes, M.; Barron, N. MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur. J. Cancer 2009, 45 (17), 3104-3118.
    • (2009) Eur. J. Cancer , vol.45 , Issue.17 , pp. 3104-3118
    • Muniyappa, M.K.1    Dowling, P.2    Henry, M.3    Meleady, P.4    Doolan, P.5    Gammell, P.6    Clynes, M.7    Barron, N.8
  • 137
    • 77953022034 scopus 로고    scopus 로고
    • Implication of microRNAs in drug resistance for designing novel cancer therapy
    • Sarkar, F.H.; Li, Y.; Wang, Z.; Kong, D.; Ali, S. Implication of microRNAs in drug resistance for designing novel cancer therapy. Drug Resist. Updat. 2010, 13 (3), 57-66.
    • (2010) Drug Resist. Updat , vol.13 , Issue.3 , pp. 57-66
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4    Ali, S.5
  • 138
    • 77952583481 scopus 로고    scopus 로고
    • Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis
    • Guo, L.; Liu, Y.; Bai, Y.; Sun, Y.; Xiao, F.; Guo, Y. Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis. Eur. J. Cancer 2010, 46 (9), 1692-1702.
    • (2010) Eur. J. Cancer , vol.46 , Issue.9 , pp. 1692-1702
    • Guo, L.1    Liu, Y.2    Bai, Y.3    Sun, Y.4    Xiao, F.5    Guo, Y.6
  • 139
    • 77955619456 scopus 로고    scopus 로고
    • miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
    • Zhu, W.; Shan, X.; Wang, T.; Shu, Y.; Liu, P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int. J. Cancer 2010, 127 (11), 2520-2529.
    • (2010) Int. J. Cancer , vol.127 , Issue.11 , pp. 2520-2529
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 141
    • 80052660944 scopus 로고    scopus 로고
    • miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway
    • Zhang, S.; Zhang, C.; Li, Y.; Wang, P.; Yue, Z.; Xie, S. miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway. Biomed. Pharmacother. 2011, 65 (6), 436-442.
    • (2011) Biomed. Pharmacother , vol.65 , Issue.6 , pp. 436-442
    • Zhang, S.1    Zhang, C.2    Li, Y.3    Wang, P.4    Yue, Z.5    Xie, S.6
  • 142
    • 84855380396 scopus 로고    scopus 로고
    • MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol
    • Han, Z.; Yang, Q.; Liu, B.; Wu, J.; Li, Y.; Yang, C.; Jiang, Y. MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol. Carcinogenesis 2012, 33 (1), 131-139.
    • (2012) Carcinogenesis , vol.33 , Issue.1 , pp. 131-139
    • Han, Z.1    Yang, Q.2    Liu, B.3    Wu, J.4    Li, Y.5    Yang, C.6    Jiang, Y.7
  • 143
    • 84856595853 scopus 로고    scopus 로고
    • MiR-100 resensitizes docetaxelresistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1
    • Feng, B.; Wang, R.; Chen, L.B. MiR-100 resensitizes docetaxelresistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1. Cancer Lett. 2012, 317 (2), 184-191.
    • (2012) Cancer Lett , vol.317 , Issue.2 , pp. 184-191
    • Feng, B.1    Wang, R.2    Chen, L.B.3
  • 144
    • 84862519692 scopus 로고    scopus 로고
    • MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3
    • Feng, B.; Wang, R.; Song, H.Z.; Chen, L.B. MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3. Cancer 2012, 118 (13), 3365-3376.
    • (2012) Cancer , vol.118 , Issue.13 , pp. 3365-3376
    • Feng, B.1    Wang, R.2    Song, H.Z.3    Chen, L.B.4
  • 145
    • 84861878901 scopus 로고    scopus 로고
    • miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A
    • Zhu, X.; Li, H.; Long, L.; Hui, L.; Chen, H.; Wang, X.; Shen, H.; Xu, W. miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A. Acta Biochim. Biophys. Sin (Shanghai). 2012, 44 (6), 519-526.
    • (2012) Acta Biochim. Biophys. Sin (Shanghai) , vol.44 , Issue.6 , pp. 519-526
    • Zhu, X.1    Li, H.2    Long, L.3    Hui, L.4    Chen, H.5    Wang, X.6    Shen, H.7    Xu, W.8
  • 146
    • 84865173199 scopus 로고    scopus 로고
    • miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1
    • Zhang, X.; Zhu, J.; Xing, R.; Tie, Y.; Fu, H.; Zheng, X.; Yu, B. miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. Lung Cancer 2012, 77 (3), 488-494.
    • (2012) Lung Cancer , vol.77 , Issue.3 , pp. 488-494
    • Zhang, X.1    Zhu, J.2    Xing, R.3    Tie, Y.4    Fu, H.5    Zheng, X.6    Yu, B.7
  • 147
    • 84873532679 scopus 로고    scopus 로고
    • Serum microRNA 125b as a diagnostic or prognostic biomarker for advanced NSCLC patients receiving cisplatin-based chemotherapy
    • Cui, E.H.; Li, H.J.; Hua, F.; Wang, B.; Mao, W.; Feng, X.R.; Li, J.Y.; Wang, X. Serum microRNA 125b as a diagnostic or prognostic biomarker for advanced NSCLC patients receiving cisplatin-based chemotherapy. Acta Pharmacol. Sin. 2013, 34 (2), 309-313.
    • (2013) Acta Pharmacol. Sin , vol.34 , Issue.2 , pp. 309-313
    • Cui, E.H.1    Li, H.J.2    Hua, F.3    Wang, B.4    Mao, W.5    Feng, X.R.6    Li, J.Y.7    Wang, X.8
  • 148
    • 84890703452 scopus 로고    scopus 로고
    • Circulating miR-22, miR- 24 and miR-34a as novel predictive biomarkers to pemetrexedbased chemotherapy in advanced non small cell lung cancer
    • Franchina T, Amodeo V, Bronte G, et al. Circulating miR-22, miR- 24 and miR-34a as novel predictive biomarkers to pemetrexedbased chemotherapy in advanced non small cell lung cancer. J. Cell. Physiol. 2014, 229 (1), 97-99.
    • (2014) J. Cell. Physiol , vol.229 , Issue.1 , pp. 97-99
    • Franchina, T.1    Amodeo, V.2    Bronte, G.3
  • 149
    • 72049101611 scopus 로고    scopus 로고
    • Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras
    • Oh, J.S.; Kim, J.J.; Byun, J.Y.; Kim, I.A. Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras. Int. J. Radiat. Oncol. Biol. Phys. 2010, 76 (1), 5-8.
    • (2010) Int. J. Radiat. Oncol. Biol. Phys , vol.76 , Issue.1 , pp. 5-8
    • Oh, J.S.1    Kim, J.J.2    Byun, J.Y.3    Kim, I.A.4
  • 151
    • 79958835291 scopus 로고    scopus 로고
    • miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1
    • Arora, H.; Qureshi, R.; Jin, S.; Park, A.K.; Park, W.Y. miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1. Exp. Mol. Med. 2011, 43 (5), 298-304.
    • (2011) Exp. Mol. Med , vol.43 , Issue.5 , pp. 298-304
    • Arora, H.1    Qureshi, R.2    Jin, S.3    Park, A.K.4    Park, W.Y.5
  • 152
    • 81855193960 scopus 로고    scopus 로고
    • Radiosensitizing effects of ectopic miR-101 on non-small-cell lung cancer cells depend on the endogenous miR-101 level
    • Chen, S.; Wang, H.; Ng, W.L.; Curran, W.J.; Wang, Y. Radiosensitizing effects of ectopic miR-101 on non-small-cell lung cancer cells depend on the endogenous miR-101 level. Int. J. Radiat. Oncol. Biol. Phys. 2011, 81 (5), 1524-1529.
    • (2011) Int. J. Radiat. Oncol. Biol. Phys , vol.81 , Issue.5 , pp. 1524-1529
    • Chen, S.1    Wang, H.2    Ng, W.L.3    Curran, W.J.4    Wang, Y.5
  • 154
    • 84867401163 scopus 로고    scopus 로고
    • miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence
    • Salim, H.; Akbar, N.S.; Zong, D.; Vaculova, A.H.; Lewensohn, R.; Moshfegh, A.; Viktorsson, K.; Zhivotovsky, B. miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence. Br. J. Cancer 2012, 107 (8), 1361-1373.
    • (2012) Br. J. Cancer , vol.107 , Issue.8 , pp. 1361-1373
    • Salim, H.1    Akbar, N.S.2    Zong, D.3    Vaculova, A.H.4    Lewensohn, R.5    Moshfegh, A.6    Viktorsson, K.7    Zhivotovsky, B.8
  • 156
    • 77957028147 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets for lung cancer
    • Cho, W.C. MicroRNAs as therapeutic targets for lung cancer. Expert Opin. Ther. Targets 2010, 14 (10), 1005-1008.
    • (2010) Expert Opin. Ther. Targets , vol.14 , Issue.10 , pp. 1005-1008
    • Cho, W.C.1
  • 157
    • 77956746299 scopus 로고    scopus 로고
    • Conquering cancer through discovery research
    • Cho, W.C. Conquering cancer through discovery research. IUBMB Life 2010, 62 (9), 655-659.
    • (2010) IUBMB Life , vol.62 , Issue.9 , pp. 655-659
    • Cho, W.C.1
  • 158
    • 77953312157 scopus 로고    scopus 로고
    • Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma
    • Young, D.D.; Connelly, C.M.; Grohmann, C.; Deiters, A. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J. Am. Chem. Soc. 2010, 132 (23), 7976-7981.
    • (2010) J. Am. Chem. Soc , vol.132 , Issue.23 , pp. 7976-7981
    • Young, D.D.1    Connelly, C.M.2    Grohmann, C.3    Deiters, A.4
  • 159
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert, M.S.; Neilson, J.R.; Sharp, P.A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 2007, 4 (9), 721-726.
    • (2007) Nat. Methods , vol.4 , Issue.9 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 160
    • 77956160758 scopus 로고    scopus 로고
    • Durable correction of inherited metabolic liver disorders requires preventing transgene off-targeting from gene therapy vectors: The value of microRNAs
    • Gonzalez-Aseguinolaza, G.; Prieto, J. Durable correction of inherited metabolic liver disorders requires preventing transgene off-targeting from gene therapy vectors: the value of microRNAs. Gastroenterology 2010, 139 (3), 726-729.
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 726-729
    • Gonzalez-Aseguinolaza, G.1    Prieto, J.2
  • 162
    • 77953484176 scopus 로고    scopus 로고
    • Small non-coding RNAs as novel therapeutics
    • Rossbach, M. Small non-coding RNAs as novel therapeutics. Curr. Mol. Med. 2010, 10 (4), 361-368.
    • (2010) Curr. Mol. Med , vol.10 , Issue.4 , pp. 361-368
    • Rossbach, M.1
  • 163
    • 77954386183 scopus 로고    scopus 로고
    • The road toward microRNA therapeutics
    • Seto, A.G. The road toward microRNA therapeutics. Int. J. Biochem. Cell Biol. 2010, 42 (8), 1298-1305.
    • (2010) Int. J. Biochem. Cell Biol , vol.42 , Issue.8 , pp. 1298-1305
    • Seto, A.G.1
  • 164
    • 77956476392 scopus 로고    scopus 로고
    • MicroRNAs: Synthesis, mechanism, function, and recent clinical trials
    • Wahid, F.; Shehzad, A.; Khan, T.; Kim, Y.Y. MicroRNAs: synthesis, mechanism, function, and recent clinical trials. Biochim. Biophys. Acta 2010, 1803 (11), 1231-1243.
    • (2010) Biochim. Biophys. Acta , vol.1803 , Issue.11 , pp. 1231-1243
    • Wahid, F.1    Shehzad, A.2    Khan, T.3    Kim, Y.Y.4
  • 165
    • 84871346487 scopus 로고    scopus 로고
    • Clinical applications for microRNAs in cancer
    • Nana-Sinkam, S.P.; Croce, C.M. Clinical applications for microRNAs in cancer. Clin. Pharmacol. Ther. 2013, 93 (1), 98-104.
    • (2013) Clin. Pharmacol. Ther , vol.93 , Issue.1 , pp. 98-104
    • Nana-Sinkam, S.P.1    Croce, C.M.2
  • 166
    • 84878630603 scopus 로고    scopus 로고
    • RNAi therapeutics and applications of MicroRNAs in cancer treatment
    • Uchino, K.; Ochiya, T.; Takeshita, F. RNAi therapeutics and applications of MicroRNAs in cancer treatment. Jpn. J. Clin. Oncol. 2013, 43 (6), 596-607.
    • (2013) Jpn. J. Clin. Oncol , vol.43 , Issue.6 , pp. 596-607
    • Uchino, K.1    Ochiya, T.2    Takeshita, F.3


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