-
1
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annual Review of Pharmacology and Toxicology. 1999;39:361-398.
-
(1999)
Annual Review of Pharmacology and Toxicology
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
2
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend DM, Tew KD. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003;22(47):7369-7375.
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
3
-
-
0023718434
-
Enhanced Dna-Repair As A Mechanism of Resistance to Cis-Diamminedichloroplatinum(Ii)
-
Eastman A, Schulte N. Enhanced Dna-Repair As A Mechanism of Resistance to Cis-Diamminedichloroplatinum(Ii). Biochemistry. 1988;27(13):4730-4734.
-
(1988)
Biochemistry
, vol.27
, Issue.13
, pp. 4730-4734
-
-
Eastman, A.1
Schulte, N.2
-
4
-
-
0030931827
-
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes
-
Kavallaris M, Kuo DYS, Burkhart CA, et al. Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes. Journal of Clinical Investigation. 1997;100(5):1282-1293.
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.5
, pp. 1282-1293
-
-
Kavallaris, M.1
Kuo, D.Y.S.2
Burkhart, C.A.3
-
5
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
-
Sethi T, Rintoul RC, Moore SM, et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo. Nature Medicine. 1999;5(6):662-668.
-
(1999)
Nature Medicine
, vol.5
, Issue.6
, pp. 662-668
-
-
Sethi, T.1
Rintoul, R.C.2
Moore, S.M.3
-
6
-
-
0033012394
-
Adhesion-dependent multicellular drug resistance
-
Green SK, Frankel A, Kerbel RS. Adhesion-dependent multicellular drug resistance. Anticancer Drug Des. 1999;14(2):153-168.
-
(1999)
Anticancer Drug Des
, vol.14
, Issue.2
, pp. 153-168
-
-
Green, S.K.1
Frankel, A.2
Kerbel, R.S.3
-
7
-
-
0141520276
-
Drug resistance and the microenvironment: Nature and nurture
-
Morin PJ. Drug resistance and the microenvironment: nature and nurture. Drug Resistance Updates. 2003;6(4):169-172.
-
(2003)
Drug Resistance Updates
, vol.6
, Issue.4
, pp. 169-172
-
-
Morin, P.J.1
-
8
-
-
8044227208
-
P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo
-
Abe Y, Ohnishi Y, Yoshimura M, et al. P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo. British Journal of Cancer. 1996;74(12):1929-1934.
-
(1996)
British Journal of Cancer
, vol.74
, Issue.12
, pp. 1929-1934
-
-
Abe, Y.1
Ohnishi, Y.2
Yoshimura, M.3
-
9
-
-
0025772679
-
Overexpression of P-Glycoprotein and Glutathione-S-Transferase-Pi in Resistant Non-Small-Cell Lung Carcinomas of Smokers
-
Volm M, Mattern J, Samsel B. Overexpression of P-Glycoprotein and Glutathione-S-Transferase-Pi in Resistant Non-Small-Cell Lung Carcinomas of Smokers. British Journal of Cancer. 1991;64(4):700-704.
-
(1991)
British Journal of Cancer
, vol.64
, Issue.4
, pp. 700-704
-
-
Volm, M.1
Mattern, J.2
Samsel, B.3
-
10
-
-
33846576044
-
Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance
-
Yabuki N, Sakata K, Yamasaki T, et al. Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance. Cancer Genetics and Cytogenetics. 2007;173(1):1-9.
-
(2007)
Cancer Genetics and Cytogenetics
, vol.173
, Issue.1
, pp. 1-9
-
-
Yabuki, N.1
Sakata, K.2
Yamasaki, T.3
-
11
-
-
39749135394
-
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)- mediated transport by the orally administered inhibitor, CBT-1 (R)
-
Robey RW, Shukla S, Finley EM, et al. Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)- mediated transport by the orally administered inhibitor, CBT-1 (R). Biochemical Pharmacology. 2008;75(6):1302-1312.
-
(2008)
Biochemical Pharmacology
, vol.75
, Issue.6
, pp. 1302-1312
-
-
Robey, R.W.1
Shukla, S.2
Finley, E.M.3
-
12
-
-
84901175255
-
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
-
In Press, Corrected Proof
-
Patil YB, Swaminathan SK, Sadhukha T, Ma L, Panyam J. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials. In Press, Corrected Proof.
-
Biomaterials
-
-
Patil, Y.B.1
Swaminathan, S.K.2
Sadhukha, T.3
Ma, L.4
Panyam, J.5
-
13
-
-
84901113606
-
648 Expression of MDR-1, MRP and LRP in human lung cancer cell lines from previously treated and untreated patients, chemosensitivity of the cell lines and effects of modulators on sensitivity
-
Helfrich B, Chan D, Helm K, Ashton M, Bunn PA. 648 Expression of MDR-1, MRP and LRP in human lung cancer cell lines from previously treated and untreated patients, chemosensitivity of the cell lines and effects of modulators on sensitivity. Lung Cancer. 1997;18 (Supplement 1):166.
-
(1997)
Lung Cancer
, vol.18
, Issue.SUPPL. 1
, pp. 166
-
-
Helfrich, B.1
Chan, D.2
Helm, K.3
Ashton, M.4
Bunn, P.A.5
-
14
-
-
21044442673
-
Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: Prognostic implications
-
Berger W, Setinek U, Hollaus P, et al. Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications. Journal of Cancer Research and Clinical Oncology. 2005;131(6):355-363.
-
(2005)
Journal of Cancer Research and Clinical Oncology
, vol.131
, Issue.6
, pp. 355-363
-
-
Berger, W.1
Setinek, U.2
Hollaus, P.3
-
15
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: The multidrug resistance-associated proteins. Journal of the National Cancer Institute. 2000;92(16):1295-1302.
-
(2000)
Journal of The National Cancer Institute
, vol.92
, Issue.16
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
16
-
-
0034895918
-
Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: Correlation of protein levels with drug response and messenger RNA levels
-
Young LC, Campling BG, Cole SPC, Deeley RG, Gerlach JH. Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: Correlation of protein levels with drug response and messenger RNA levels. Clinical Cancer Research. 2001;7(6):1798-1804.
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.6
, pp. 1798-1804
-
-
Young, L.C.1
Campling, B.G.2
Cole, S.P.C.3
Deeley, R.G.4
Gerlach, J.H.5
-
17
-
-
61449341856
-
ABCC10/MRP7 is associated with vinorelbine resistance in non-small cell lung cancer
-
Bessho Y, Oguri T, Ozasa H, et al. ABCC10/MRP7 is associated with vinorelbine resistance in non-small cell lung cancer. Oncology Reports. 2009;21(1):263-268.
-
(2009)
Oncology Reports
, vol.21
, Issue.1
, pp. 263-268
-
-
Bessho, Y.1
Oguri, T.2
Ozasa, H.3
-
18
-
-
0042494394
-
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76
-
Awasthi S, Singhal SS, Singhal J, Cheng JH, Zimniak P, Awasthi YC. Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76. International Journal of Oncology. 2003;22(4):713-720.
-
(2003)
International Journal of Oncology
, vol.22
, Issue.4
, pp. 713-720
-
-
Awasthi, S.1
Singhal, S.S.2
Singhal, J.3
Cheng, J.H.4
Zimniak, P.5
Awasthi, Y.C.6
-
19
-
-
0041492605
-
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity
-
Awasthi S, Singhal SS, Singhal J, Yang YS, Zimniak P, Awasthi YC. Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity. International Journal of Oncology. 2003;22(4):721-732.
-
(2003)
International Journal of Oncology
, vol.22
, Issue.4
, pp. 721-732
-
-
Awasthi, S.1
Singhal, S.S.2
Singhal, J.3
Yang, Y.S.4
Zimniak, P.5
Awasthi, Y.C.6
-
20
-
-
13444291026
-
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer
-
Stuckler D, Singhal J, Singhal SS, Yadav S, Awasthi YC, Awasthi S. RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer. Cancer Research. 2005;65(3):991-998.
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 991-998
-
-
Stuckler, D.1
Singhal, J.2
Singhal, S.S.3
Yadav, S.4
Awasthi, Y.C.5
Awasthi, S.6
-
21
-
-
0027466646
-
Overexpression of A M(R) 110,000 Vesicular Protein in Non-P-Glycoprotein-Mediated Multidrug Resistance
-
Scheper RJ, Broxterman HJ, Scheffer GL, et al. Overexpression of A M(R) 110,000 Vesicular Protein in Non-P-Glycoprotein-Mediated Multidrug Resistance. Cancer Research. 1993;53(7):1475-1479.
-
(1993)
Cancer Research
, vol.53
, Issue.7
, pp. 1475-1479
-
-
Scheper, R.J.1
Broxterman, H.J.2
Scheffer, G.L.3
-
22
-
-
0030091652
-
Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors
-
Izquierdo MA, Scheffer GL, Flens MJ, et al. Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors. American Journal of Pathology. 1996;148(3):877-887.
-
(1996)
American Journal of Pathology
, vol.148
, Issue.3
, pp. 877-887
-
-
Izquierdo, M.A.1
Scheffer, G.L.2
Flens, M.J.3
-
23
-
-
0033530286
-
Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells
-
Kitazono M, Sumizawa T, Takebayashi Y, et al. Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells. Journal of the National Cancer Institute. 1999;91(19):1647-1653.
-
(1999)
Journal of The National Cancer Institute
, vol.91
, Issue.19
, pp. 1647-1653
-
-
Kitazono, M.1
Sumizawa, T.2
Takebayashi, Y.3
-
24
-
-
0029818849
-
Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues
-
Dingemans AMC, vanArkOtte J, vanderValk P, et al. Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues. Annals of Oncology. 1996;7(6):625-630.
-
(1996)
Annals of Oncology
, vol.7
, Issue.6
, pp. 625-630
-
-
Dingemans, A.M.C.1
Vanarkotte, J.2
Vandervalk, P.3
-
25
-
-
0025781307
-
Metallothionein Content Correlates with the Sensitivity of Human Small-Cell Lung- Cancer Cell-Lines to Cisplatin
-
Kasahara K, Fujiwara Y, Nishio K, et al. Metallothionein Content Correlates with the Sensitivity of Human Small-Cell Lung- Cancer Cell-Lines to Cisplatin. Cancer Research. 1991;51(12): 3237-3242.
-
(1991)
Cancer Research
, vol.51
, Issue.12
, pp. 3237-3242
-
-
Kasahara, K.1
Fujiwara, Y.2
Nishio, K.3
-
26
-
-
0023696141
-
Overexpression of Metallothionein Confers Resistance to Anticancer Drugs
-
Kelley SL, Basu A, Teicher BA, Hacker MP, Hamer DH, Lazo JS. Overexpression of Metallothionein Confers Resistance to Anticancer Drugs. Science. 1988;241(4874):1813-1815.
-
(1988)
Science
, vol.241
, Issue.4874
, pp. 1813-1815
-
-
Kelley, S.L.1
Basu, A.2
Teicher, B.A.3
Hacker, M.P.4
Hamer, D.H.5
Lazo, J.S.6
-
27
-
-
55249114464
-
Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells
-
Yang M, Chitambar CR. Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells. Free Radical Biology and Medicine. 2008;45(6):763-772.
-
(2008)
Free Radical Biology and Medicine
, vol.45
, Issue.6
, pp. 763-772
-
-
Yang, M.1
Chitambar, C.R.2
-
29
-
-
0030802387
-
Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma
-
Hoey JG, Garrett SH, Sens MA, Todd JH, Sens DA. Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma. Toxicology Letters. 1997;92(2):149-160.
-
(1997)
Toxicology Letters
, vol.92
, Issue.2
, pp. 149-160
-
-
Hoey, J.G.1
Garrett, S.H.2
Sens, M.A.3
Todd, J.H.4
Sens, D.A.5
-
30
-
-
0027994282
-
Metallothionein-Iii Is Expressed in Neurons That Sequester Zinc in Synaptic Vesicles
-
Masters BA, Quaife CJ, Erickson JC, et al. Metallothionein-Iii Is Expressed in Neurons That Sequester Zinc in Synaptic Vesicles. Journal of Neuroscience. 1994;14(10):5844-5857.
-
(1994)
Journal of Neuroscience
, vol.14
, Issue.10
, pp. 5844-5857
-
-
Masters, B.A.1
Quaife, C.J.2
Erickson, J.C.3
-
31
-
-
0028289610
-
Induction of A New Metallothionein Isoform (Mt-Iv) Occurs During Differentiation of Stratified Squamous Epithelia
-
Quaife CJ, Findley SD, Erickson JC, et al. Induction of A New Metallothionein Isoform (Mt-Iv) Occurs During Differentiation of Stratified Squamous Epithelia. Biochemistry. 1994;33(23):7250-7259.
-
(1994)
Biochemistry
, vol.33
, Issue.23
, pp. 7250-7259
-
-
Quaife, C.J.1
Findley, S.D.2
Erickson, J.C.3
-
33
-
-
0034860415
-
Expression of metallothionein in colorectal cancers and synchronous liver metastases
-
Hishikawa Y, Kohno H, Ueda S, et al. Expression of metallothionein in colorectal cancers and synchronous liver metastases. Oncology. 2001;61(2):162-167.
-
(2001)
Oncology
, vol.61
, Issue.2
, pp. 162-167
-
-
Hishikawa, Y.1
Kohno, H.2
Ueda, S.3
-
35
-
-
0032819103
-
Metallothionein expression and nuclear size-in benign, borderline, and malignant serous ovarian tumours
-
Tan Y, Sinniah R, Bay BH, Singh G. Metallothionein expression and nuclear size-in benign, borderline, and malignant serous ovarian tumours. Journal of Pathology. 1999;189(1):60-65.
-
(1999)
Journal of Pathology
, vol.189
, Issue.1
, pp. 60-65
-
-
Tan, Y.1
Sinniah, R.2
Bay, B.H.3
Singh, G.4
-
36
-
-
0032885943
-
Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus
-
Hishikawa Y, Koji T, Dhar DK, Kinugasa S, Yamaguchi M, Nagasue N. Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus. British Journal of Cancer. 1999;81(4):712-720.
-
(1999)
British Journal of Cancer
, vol.81
, Issue.4
, pp. 712-720
-
-
Hishikawa, Y.1
Koji, T.2
Dhar, D.K.3
Kinugasa, S.4
Yamaguchi, M.5
Nagasue, N.6
-
37
-
-
0036284478
-
Prognostic significance of metallothionein in human gastrointestinal cancer
-
Janssen AML, van Duijn W, Kubben FJGM, Griffioen G, Lamers CBHW, van Krieken JHJM, et al. Prognostic significance of metallothionein in human gastrointestinal cancer. Clinical Cancer Research. 2002;8(6):1889-1896.
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.6
, pp. 1889-1896
-
-
Janssen, A.M.L.1
van Duijn, W.2
Kubben, F.J.G.M.3
Griffioen, G.4
Lamers, C.B.H.W.5
van Krieken, J.H.J.M.6
-
38
-
-
0036159956
-
Expression of metallothionein in lung carcinoma: Correlation with histological type and
-
Theocharis S, Karkantaris C, Philipides T, et al. Expression of metallothionein in lung carcinoma: correlation with histological type and. Histopathology. 2002;40(2):143-151.
-
(2002)
Histopathology
, vol.40
, Issue.2
, pp. 143-151
-
-
Theocharis, S.1
Karkantaris, C.2
Philipides, T.3
-
39
-
-
0030917266
-
Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer
-
Hishikawa Y, Abe S, Kinugasa S, et al. Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology. 1997;54(4):342-347.
-
(1997)
Oncology
, vol.54
, Issue.4
, pp. 342-347
-
-
Hishikawa, Y.1
Abe, S.2
Kinugasa, S.3
-
40
-
-
0034685453
-
Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: A specific gene therapy strategy
-
Vandier D, Calvez V, Massade L, et al. Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: a specific gene therapy strategy. Journal of the National Cancer Institute. 2000;92(8):642-647.
-
(2000)
Journal of The National Cancer Institute
, vol.92
, Issue.8
, pp. 642-647
-
-
Vandier, D.1
Calvez, V.2
Massade, L.3
-
41
-
-
0011331810
-
Increased Resistance to Doxorubicin in Human Non-Small-Cell Lung Carcinomas with Metallothionein Expression
-
Mattern J, Volm M. Increased Resistance to Doxorubicin in Human Non-Small-Cell Lung Carcinomas with Metallothionein Expression. International Journal of Oncology. 1992;1(6):687-689.
-
(1992)
International Journal of Oncology
, vol.1
, Issue.6
, pp. 687-689
-
-
Mattern, J.1
Volm, M.2
-
42
-
-
0028106016
-
Glutathione-Associated Enzymes in Anticancer Drug- Resistance
-
Tew KD. Glutathione-Associated Enzymes in Anticancer Drug- Resistance. Cancer Research. 1994;54(16):4313-4320.
-
(1994)
Cancer Research
, vol.54
, Issue.16
, pp. 4313-4320
-
-
Tew, K.D.1
-
43
-
-
0023628442
-
Immunocytochemical Evidence for the Expression of Gst1, Gst2, and Gst3 Gene Loci for Glutathione- S-Transferase in Human-Lung
-
Awasthi YC, Singh SV, Ahmad H, Moller PC. Immunocytochemical Evidence for the Expression of Gst1, Gst2, and Gst3 Gene Loci for Glutathione- S-Transferase in Human-Lung. Lung. 1987;165(6):323-332.
-
(1987)
Lung
, vol.165
, Issue.6
, pp. 323-332
-
-
Awasthi, Y.C.1
Singh, S.V.2
Ahmad, H.3
Moller, P.C.4
-
44
-
-
0023866295
-
Elevation of Glutathione Transferase-Activity in Human-Lung Tumor
-
Diilio C, Delboccio G, Aceto A, Casaccia R, Mucilli F, Federici G. Elevation of Glutathione Transferase-Activity in Human-Lung Tumor. Carcinogenesis. 1988;9(2):335-340.
-
(1988)
Carcinogenesis
, vol.9
, Issue.2
, pp. 335-340
-
-
Diilio, C.1
Delboccio, G.2
Aceto, A.3
Casaccia, R.4
Mucilli, F.5
Federici, G.6
-
45
-
-
0023213749
-
Glutathione S-Transferases in Nitrogen Mustard-Resistant and Mustard-Sensitive Cell-Lines
-
Buller AL, Clapper ML, Tew KD. Glutathione S-Transferases in Nitrogen Mustard-Resistant and Mustard-Sensitive Cell-Lines. Molecular Pharmacology. 1987;31(6):575-578.
-
(1987)
Molecular Pharmacology
, vol.31
, Issue.6
, pp. 575-578
-
-
Buller, A.L.1
Clapper, M.L.2
Tew, K.D.3
-
46
-
-
0025237403
-
Glutathione-S-Transferase-Pi As A Determinant of Drug-Resistance in Transfectant Cell-Lines
-
Nakagawa K, Saijo N, Tsuchida S, et al. Glutathione-S-Transferase-Pi As A Determinant of Drug-Resistance in Transfectant Cell-Lines. Journal of Biological Chemistry. 1990;265(8):4296-4301.
-
(1990)
Journal of Biological Chemistry
, vol.265
, Issue.8
, pp. 4296-4301
-
-
Nakagawa, K.1
Saijo, N.2
Tsuchida, S.3
-
47
-
-
0026594202
-
Levels of Expression of the Mdr1 Gene and Glutathione- S-Transferase Gene-2 and Gene-3 and Response to Chemotherapy in Multiple-Myeloma
-
Linsenmeyer ME, Jefferson S, Wolf M, Matthews JP, Board PG, Woodcock DM. Levels of Expression of the Mdr1 Gene and Glutathione- S-Transferase Gene-2 and Gene-3 and Response to Chemotherapy in Multiple-Myeloma. British Journal of Cancer. 1992;65(3):471-475.
-
(1992)
British Journal of Cancer
, vol.65
, Issue.3
, pp. 471-475
-
-
Linsenmeyer, M.E.1
Jefferson, S.2
Wolf, M.3
Matthews, J.P.4
Board, P.G.5
Woodcock, D.M.6
-
49
-
-
0031930390
-
Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity
-
Kinnula K, Linnainmaa K, Raivio KO, Kinnula VL. Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity. British Journal of Cancer. 1998;77(7):1097-1102.
-
(1998)
British Journal of Cancer
, vol.77
, Issue.7
, pp. 1097-1102
-
-
Kinnula, K.1
Linnainmaa, K.2
Raivio, K.O.3
Kinnula, V.L.4
-
51
-
-
61549087775
-
Cisplatin: A review of toxicities and therapeutic applications
-
Barabas K, Milner R, Lurie D, Adin C. Cisplatin: a review of toxicities and therapeutic applications. Veterinary and Comparative Oncology. 2008;6(1):1-18.
-
(2008)
Veterinary and Comparative Oncology
, vol.6
, Issue.1
, pp. 1-18
-
-
Barabas, K.1
Milner, R.2
Lurie, D.3
Adin, C.4
-
52
-
-
34548398070
-
Current status of excision repair cross complementing-group 1 (ERCC1) in cancer
-
Gossage L, Madhusudan S. Current status of excision repair cross complementing-group 1 (ERCC1) in cancer. Cancer Treatment Reviews. 2007;33(6):565-577.
-
(2007)
Cancer Treatment Reviews
, vol.33
, Issue.6
, pp. 565-577
-
-
Gossage, L.1
Madhusudan, S.2
-
53
-
-
69449090272
-
The Relationship of Platinum Resistance and ERCC1 Protein Expression in Epithelial Ovarian Cancer
-
Steffensen KD, Waldstrom M, Jakobsen A. The Relationship of Platinum Resistance and ERCC1 Protein Expression in Epithelial Ovarian Cancer. International Journal of Gynecological Cancer. 2009;19(5):820-825.
-
(2009)
International Journal of Gynecological Cancer
, vol.19
, Issue.5
, pp. 820-825
-
-
Steffensen, K.D.1
Waldstrom, M.2
Jakobsen, A.3
-
54
-
-
45749108232
-
The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer
-
Schettino C, Bareschino MA, Maione P, Rossi A, Ciardiello F, Gridelli C. The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer. Current Genomics. 2008;9(4):252-262.
-
(2008)
Current Genomics
, vol.9
, Issue.4
, pp. 252-262
-
-
Schettino, C.1
Bareschino, M.A.2
Maione, P.3
Rossi, A.4
Ciardiello, F.5
Gridelli, C.6
-
55
-
-
0036890375
-
DNA repair and cisplatin resistance in non-small-cell lung cancer
-
Rosell R, Lord RVN, Taron M, Reguart N. DNA repair and cisplatin resistance in non-small-cell lung cancer. Lung Cancer. 2002;38(3): 217-227.
-
(2002)
Lung Cancer
, vol.38
, Issue.3
, pp. 217-227
-
-
Rosell, R.1
Lord, R.V.N.2
Taron, M.3
Reguart, N.4
-
56
-
-
0035988959
-
Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer
-
Lord RVN, Brabender J, Gandara D, et al. Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. Clinical Cancer Research. 2002;8(7):2286-2291.
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2286-2291
-
-
Lord, R.V.N.1
Brabender, J.2
Gandara, D.3
-
57
-
-
38049125557
-
Mechanisms and functions of DNA mismatch repair
-
Li GM. Mechanisms and functions of DNA mismatch repair. Cell Research. 2008;18(1):85-98.
-
(2008)
Cell Research
, vol.18
, Issue.1
, pp. 85-98
-
-
Li, G.M.1
-
58
-
-
51849109383
-
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine
-
Liu A, Yoshioka KI, Salerno V, Hsieh P. The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine. Journal of Cellular Biochemistry. 2008;105(1):245-254.
-
(2008)
Journal of Cellular Biochemistry
, vol.105
, Issue.1
, pp. 245-254
-
-
Liu, A.1
Yoshioka, K.I.2
Salerno, V.3
Hsieh, P.4
-
59
-
-
61349196954
-
Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2 '-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs
-
Preston TJ, Henderson JT, McCallum GP, Wells PG. Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2 '-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs. Molecular Cancer Therapeutics. 2009;8(7):2015-2026.
-
(2009)
Molecular Cancer Therapeutics
, vol.8
, Issue.7
, pp. 2015-2026
-
-
Preston, T.J.1
Henderson, J.T.2
McCallum, G.P.3
Wells, P.G.4
-
60
-
-
67649784587
-
Mismatch Repair Protein Deficiency Compromises Cisplatin-induced Apoptotic Signaling
-
Topping RP, Wilkinson JC, Scarpinato KD. Mismatch Repair Protein Deficiency Compromises Cisplatin-induced Apoptotic Signaling. Journal of Biological Chemistry. 2009;284(21):14029-14039.
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.21
, pp. 14029-14039
-
-
Topping, R.P.1
Wilkinson, J.C.2
Scarpinato, K.D.3
-
61
-
-
44449097296
-
Targeting base excision repair for chemosensitization
-
Adhikari S, Choudhury S, Mitra PS, Dubash JJ, Sajankila SP, Roy R. Targeting base excision repair for chemosensitization. Anti-Cancer Agents in Medicinal Chemistry. 2008;8(4):351-357.
-
(2008)
Anti-Cancer Agents In Medicinal Chemistry
, vol.8
, Issue.4
, pp. 351-357
-
-
Adhikari, S.1
Choudhury, S.2
Mitra, P.S.3
Dubash, J.J.4
Sajankila, S.P.5
Roy, R.6
-
62
-
-
62349120246
-
DNA Repair in Mammalian Cells
-
Robertson AB, Klungland A, Rognes T, Leiros I. DNA Repair in Mammalian Cells. Cellular and Molecular Life Sciences. 2009;66(6):981-993.
-
(2009)
Cellular and Molecular Life Sciences
, vol.66
, Issue.6
, pp. 981-993
-
-
Robertson, A.B.1
Klungland, A.2
Rognes, T.3
Leiros, I.4
-
64
-
-
19344370467
-
Mechanism of DNA double-strand break repair by non-homologous end joining
-
Hefferin ML, Tomkinson AE. Mechanism of DNA double-strand break repair by non-homologous end joining. Dna Repair. 2005;4(6): 639-648.
-
(2005)
Dna Repair
, vol.4
, Issue.6
, pp. 639-648
-
-
Hefferin, M.L.1
Tomkinson, A.E.2
-
65
-
-
22144452193
-
Non-homologous DNA end joining repair in normal and leukemic cells depends on the substrate ends
-
Pastwa E, Poplawski T, Czechowska A, Malinowski M, Blasiak J. Non-homologous DNA end joining repair in normal and leukemic cells depends on the substrate ends. Zeitschrift fur Naturforschung C-A Journal of Biosciences. 2005;60(5-6):493-500.
-
(2005)
Zeitschrift Fur Naturforschung C-A Journal of Biosciences
, vol.60
, Issue.5-6
, pp. 493-500
-
-
Pastwa, E.1
Poplawski, T.2
Czechowska, A.3
Malinowski, M.4
Blasiak, J.5
-
66
-
-
34548106910
-
The antipsychotic drug trifluoperazine inhibits DNA repair and sensitizes non-small cell lung carcinoma cells to DNA double-strand break-induced cell death
-
Polischouk AG, Holgersson A, Zong DL, et al. The antipsychotic drug trifluoperazine inhibits DNA repair and sensitizes non-small cell lung carcinoma cells to DNA double-strand break-induced cell death. Molecular Cancer Therapeutics. 2007;6(8):2303-2309.
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.8
, pp. 2303-2309
-
-
Polischouk, A.G.1
Holgersson, A.2
Zong, D.L.3
-
67
-
-
54249169756
-
DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin
-
Friesen C, Uhl M, Pannicke U, Schwarz K, Miltner E, Debatin KM. DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin. Molecular Biology of the Cell. 2008;19(8):3283-3289.
-
(2008)
Molecular Biology of The Cell
, vol.19
, Issue.8
, pp. 3283-3289
-
-
Friesen, C.1
Uhl, M.2
Pannicke, U.3
Schwarz, K.4
Miltner, E.5
Debatin, K.M.6
-
68
-
-
38049155945
-
Regulation of DNA doublestrand break repair pathway choice
-
Shrivastav M, De Haro LP, Nickoloff JA. Regulation of DNA doublestrand break repair pathway choice. Cell Research. 2008;18(1): 134-147.
-
(2008)
Cell Research
, vol.18
, Issue.1
, pp. 134-147
-
-
Shrivastav, M.1
de Haro, L.P.2
Nickoloff, J.A.3
-
69
-
-
38949103346
-
Clinical relevance of the homologous recombination machinery in cancer therapy
-
Miyagawa K. Clinical relevance of the homologous recombination machinery in cancer therapy. Cancer Science. 2008;99(2):187-194.
-
(2008)
Cancer Science
, vol.99
, Issue.2
, pp. 187-194
-
-
Miyagawa, K.1
-
70
-
-
0035890270
-
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells
-
Niedernhofer LJ, Essers J, Weeda G, et al. The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells. Embo Journal. 2001;20(22):6540-6549.
-
(2001)
Embo Journal
, vol.20
, Issue.22
, pp. 6540-6549
-
-
Niedernhofer, L.J.1
Essers, J.2
Weeda, G.3
-
71
-
-
0037986421
-
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer
-
Hansen LT, Lundin C, Spang-Thomsen M, Petersen LN, Helleday T. The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer. International Journal of Cancer. 2003;105(4):472-479.
-
(2003)
International Journal of Cancer
, vol.105
, Issue.4
, pp. 472-479
-
-
Hansen, L.T.1
Lundin, C.2
Spang-Thomsen, M.3
Petersen, L.N.4
Helleday, T.5
-
72
-
-
12444250680
-
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer
-
Hansen LT, Lundin C, Helleday T, et al. DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer. Lung Cancer. 2003;40(2): 157-164.
-
(2003)
Lung Cancer
, vol.40
, Issue.2
, pp. 157-164
-
-
Hansen, L.T.1
Lundin, C.2
Helleday, T.3
-
73
-
-
0041695633
-
Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase over expression
-
Sigmond J, Backus HHJ, Wouters D, Temmink OH, Jansen G, Peters GJ. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase over expression. Biochemical Pharmacology. 2003;66(3):431-438.
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.3
, pp. 431-438
-
-
Sigmond, J.1
Backus, H.H.J.2
Wouters, D.3
Temmink, O.H.4
Jansen, G.5
Peters, G.J.6
-
75
-
-
58049203852
-
Detection of gemcitabine-resistant genes expression in lung cancer cell lines using real-time PCR
-
Lin L, Liu X, Rao Y, Wang W, Wang S, Song S. Detection of gemcitabine-resistant genes expression in lung cancer cell lines using real-time PCR. The Chinese-German Journal of Clinical Oncology. 2008;7(12):682-685.
-
(2008)
The Chinese-German Journal of Clinical Oncology
, vol.7
, Issue.12
, pp. 682-685
-
-
Lin, L.1
Liu, X.2
Rao, Y.3
Wang, W.4
Wang, S.5
Song, S.6
-
76
-
-
0034748021
-
Inhibition of drug-induced Fas ligand transcription and apoptosis by Bcl-X-L
-
Biswas RS, Cha HJ, Hardwick JM, Srivastava RK. Inhibition of drug-induced Fas ligand transcription and apoptosis by Bcl-X-L. Molecular and Cellular Biochemistry. 2001;225(1-2):7-20.
-
(2001)
Molecular and Cellular Biochemistry
, vol.225
, Issue.1-2
, pp. 7-20
-
-
Biswas, R.S.1
Cha, H.J.2
Hardwick, J.M.3
Srivastava, R.K.4
-
77
-
-
0033584231
-
Bcl-2-mediated drug resistance: Inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription
-
Srivastava RK, Sasaki CY, Hardwick JM, Longo DL. Bcl-2-mediated drug resistance: Inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription. Journal of Experimental Medicine. 1999;190(2):253-265.
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.2
, pp. 253-265
-
-
Srivastava, R.K.1
Sasaki, C.Y.2
Hardwick, J.M.3
Longo, D.L.4
-
78
-
-
16244366499
-
Bcl-2 overexpression enhances in vitro sensitivity against docetaxel in non-small cell lung cancer
-
Inoue Y, Gika M, Abiko T, et al. Bcl-2 overexpression enhances in vitro sensitivity against docetaxel in non-small cell lung cancer. Oncology Reports. 2005;13(2):259-264.
-
(2005)
Oncology Reports
, vol.13
, Issue.2
, pp. 259-264
-
-
Inoue, Y.1
Gika, M.2
Abiko, T.3
-
79
-
-
0030762122
-
Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
-
Los M, Herr I, Friesen C, Fulda S, SchulzeOsthoff K, Debatin KM. Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood. 1997;90(8):3118-3129.
-
(1997)
Blood
, vol.90
, Issue.8
, pp. 3118-3129
-
-
Los, M.1
Herr, I.2
Friesen, C.3
Fulda, S.4
Schulzeosthoff, K.5
Debatin, K.M.6
-
80
-
-
0346157019
-
Rescue of death receptor and mitochondrial apoptosis signaling in resistant human NSCLC in vivo
-
Okouoyo S, Herzer K, Ucur E, et al. Rescue of death receptor and mitochondrial apoptosis signaling in resistant human NSCLC in vivo. International Journal of Cancer. 2004;108(4):580-587.
-
(2004)
International Journal of Cancer
, vol.108
, Issue.4
, pp. 580-587
-
-
Okouoyo, S.1
Herzer, K.2
Ucur, E.3
-
81
-
-
0032782809
-
Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas
-
Volm M, Mattern J, Koomagi R. Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas. Anticancer Research. 1999;19(3A):1669-1671.
-
(1999)
Anticancer Research
, vol.19
, Issue.3 A
, pp. 1669-1671
-
-
Volm, M.1
Mattern, J.2
Koomagi, R.3
-
82
-
-
0037442965
-
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide
-
Yang LL, Mashima T, Sato S, et al. Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Research. 2003;63(4):831-837.
-
(2003)
Cancer Research
, vol.63
, Issue.4
, pp. 831-837
-
-
Yang, L.L.1
Mashima, T.2
Sato, S.3
-
83
-
-
0032986544
-
A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers
-
Monzo M, Rosell R, Felip E, et al. A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers. Journal of Clinical Oncology. 1999;17(7):2100-2104.
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.7
, pp. 2100-2104
-
-
Monzo, M.1
Rosell, R.2
Felip, E.3
-
84
-
-
0043025147
-
Survivin gene expression in early-stage non-small cell lung cancer
-
Falleni M, Pellegrini C, Marchetti A, et al. Survivin gene expression in early-stage non-small cell lung cancer. Journal of Pathology. 2003;200(5):620-626.
-
(2003)
Journal of Pathology
, vol.200
, Issue.5
, pp. 620-626
-
-
Falleni, M.1
Pellegrini, C.2
Marchetti, A.3
-
85
-
-
8444253671
-
Expression of survivin mRNA and livin mRNA in non-small-cell lung cancer
-
Tanabe H, Yagihashi A, Tsuji N, Shijubo Y, Abe S, Watanabe N. Expression of survivin mRNA and livin mRNA in non-small-cell lung cancer. Lung Cancer. 2004;46(3):299-304.
-
(2004)
Lung Cancer
, vol.46
, Issue.3
, pp. 299-304
-
-
Tanabe, H.1
Yagihashi, A.2
Tsuji, N.3
Shijubo, Y.4
Abe, S.5
Watanabe, N.6
-
86
-
-
0028955388
-
Epidermal Growth Factor-Related Peptides and Their Receptors in Human Malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal Growth Factor-Related Peptides and Their Receptors in Human Malignancies. Critical Reviews in Oncology/Hematology. 1995;19(3): 183-232.
-
(1995)
Critical Reviews In Oncology/Hematology
, vol.19
, Issue.3
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
87
-
-
0037010087
-
Epidermal growth factor receptor expression, signal pathway, and inhibitors in non-small cell lung cancer
-
Bunn PA, Franklin W. Epidermal growth factor receptor expression, signal pathway, and inhibitors in non-small cell lung cancer. Seminars in Oncology. 2002;29(5):38-44.
-
(2002)
Seminars In Oncology
, vol.29
, Issue.5
, pp. 38-44
-
-
Bunn, P.A.1
Franklin, W.2
-
89
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
Camp ER, Summy J, Bauer TW, Liu WB, Gallick GE, Ellis LM. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clinical Cancer Research. 2005;11(1):397-405.
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.1
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.B.4
Gallick, G.E.5
Ellis, L.M.6
-
90
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science. 2004;304(5676):1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
91
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. New England Journal of Medicine. 2004;350(21):2129-2139.
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
92
-
-
35548962203
-
Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer
-
Mitsudomi T, Yatabe Y. Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer. Cancer Science. 2007;98(12):1817-1824.
-
(2007)
Cancer Science
, vol.98
, Issue.12
, pp. 1817-1824
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
93
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007;316(5827):1039-1043.
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
-
94
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. New England Journal of Medicine. 2005;352(8):786-792.
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.8
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
95
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ, et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. Plos Medicine. 2005;2(1):57-61.
-
(2005)
Plos Medicine
, vol.2
, Issue.1
, pp. 57-61
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
96
-
-
0028957113
-
Molecular and Cellular Aspects of the Insulin-Like Growth-Factor-I Receptor
-
Leroith D, Werner H, Beitnerjohnson D, Roberts CT. Molecular and Cellular Aspects of the Insulin-Like Growth-Factor-I Receptor. Endocrine Reviews. 1995;16(2):143-163.
-
(1995)
Endocrine Reviews
, vol.16
, Issue.2
, pp. 143-163
-
-
Leroith, D.1
Werner, H.2
Beitnerjohnson, D.3
Roberts, C.T.4
-
97
-
-
50849141873
-
Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors
-
Zucali PA, Ruiz MG, Giovannetti E, et al. Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors. Annals of Oncology. 2008;19(9):1605-1612.
-
(2008)
Annals of Oncology
, vol.19
, Issue.9
, pp. 1605-1612
-
-
Zucali, P.A.1
Ruiz, M.G.2
Giovannetti, E.3
-
98
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science. 1998;282(5392): 1318-1321.
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
-
99
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3- kinase AKT pathway
-
Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3- kinase AKT pathway. Proceedings of the National Academy of Sciences of the United States of America. 1999;96(8):4240-4245.
-
(1999)
Proceedings of The National Academy of Sciences of The United States of America
, vol.96
, Issue.8
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
100
-
-
65949086609
-
PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR
-
Sos ML, Koker M, Weir BA, et al. PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR. Cancer Research. 2009;69(8):3256-3261.
-
(2009)
Cancer Research
, vol.69
, Issue.8
, pp. 3256-3261
-
-
Sos, M.L.1
Koker, M.2
Weir, B.A.3
-
101
-
-
70349086575
-
The drugresistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro
-
Zhuang HQ, Wang J, Yuan ZY, Zhao LJ, Wang P, Wang CL. The drugresistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro. Journal of Experimental and Clinical Cancer Research. 2009;28.
-
(2009)
Journal of Experimental and Clinical Cancer Research
, vol.28
-
-
Zhuang, H.Q.1
Wang, J.2
Yuan, Z.Y.3
Zhao, L.J.4
Wang, P.5
Wang, C.L.6
-
102
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis. Cancer Research. 2001;61(13):5090-5101.
-
(2001)
Cancer Research
, vol.61
, Issue.13
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
-
103
-
-
0842289982
-
Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy
-
Ciardiello F, Bianco R, Caputo R, et al. Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. Clinical Cancer Research. 2004;10(2):784-793.
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.2
, pp. 784-793
-
-
Ciardiello, F.1
Bianco, R.2
Caputo, R.3
-
104
-
-
34548443831
-
Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition. Cellular Signalling
-
Holmes K, Roberts OL, Thomas AM, Cross MJ. Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition. Cellular Signalling. 2007;19(10):2003 2012.
-
(2012)
2007;19(10)
, pp. 2003
-
-
Holmes, K.1
Roberts, O.L.2
Thomas, A.M.3
Cross, M.J.4
-
105
-
-
0038010147
-
Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines
-
Lantuejoul S, Constantin B, Drabkin H, Brambilla C, Roche J, Brambilla E. Expression of VEGF, semaphorin SEMA3F, and their common receptors neuropilins NP1 and NP2 in preinvasive bronchial lesions, lung tumours, and cell lines. Journal of Pathology. 2003;200(3):336-347.
-
(2003)
Journal of Pathology
, vol.200
, Issue.3
, pp. 336-347
-
-
Lantuejoul, S.1
Constantin, B.2
Drabkin, H.3
Brambilla, C.4
Roche, J.5
Brambilla, E.6
-
107
-
-
23644434724
-
Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells
-
Wey JS, Gray MJ, Fan F, et al. Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells. British Journal of Cancer. 2005;93(2):233-241.
-
(2005)
British Journal of Cancer
, vol.93
, Issue.2
, pp. 233-241
-
-
Wey, J.S.1
Gray, M.J.2
Fan, F.3
-
109
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 1997;88(3):323-331.
-
(1997)
Cell
, vol.88
, Issue.3
, pp. 323-331
-
-
Levine, A.J.1
-
110
-
-
0028171454
-
P53 Gene-Mutations Are Associated with Decreased Sensitivity of Human Lymphoma-Cells to DnaDamaging Agents
-
Fan SJ, Eldeiry WS, Bae I, et al. P53 Gene-Mutations Are Associated with Decreased Sensitivity of Human Lymphoma-Cells to DnaDamaging Agents. Cancer Research. 1994;54(22):5824-5830.
-
(1994)
Cancer Research
, vol.54
, Issue.22
, pp. 5824-5830
-
-
Fan, S.J.1
Eldeiry, W.S.2
Bae, I.3
-
111
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F, Hwang PM, Torrance C, et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. Journal of Clinical Investigation. 1999;104(3):263-269.
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.3
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
-
112
-
-
0030903281
-
Role of p53 in drug resistance in ovarian cancer
-
Shelling AN. Role of p53 in drug resistance in ovarian cancer. Lancet. 1997;349(9054):744-745.
-
(1997)
Lancet
, vol.349
, Issue.9054
, pp. 744-745
-
-
Shelling, A.N.1
-
113
-
-
0033063875
-
Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations
-
Monzo M, Rosell R, Sanchez JJ, et al. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. Journal of Clinical Oncology. 1999;17(6):1786-1793.
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.6
, pp. 1786-1793
-
-
Monzo, M.1
Rosell, R.2
Sanchez, J.J.3
-
114
-
-
0034078907
-
Modulation of paolitaxel resistance by annexin IV in human cancer cell lines
-
Han EKH, Tahir SK, Cherian SP, Collins N, Ng SC. Modulation of paolitaxel resistance by annexin IV in human cancer cell lines. British Journal of Cancer. 2000;83(1):83-88.
-
(2000)
British Journal of Cancer
, vol.83
, Issue.1
, pp. 83-88
-
-
Han, E.K.H.1
Tahir, S.K.2
Cherian, S.P.3
Collins, N.4
Ng, S.C.5
-
115
-
-
0033817518
-
Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341
-
Frankel A, Man S, Elliott P, Adams J, Kerbel RS. Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341. Clinical Cancer Research. 2000;6(9):3719-3728.
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.9
, pp. 3719-3728
-
-
Frankel, A.1
Man, S.2
Elliott, P.3
Adams, J.4
Kerbel, R.S.5
-
116
-
-
0037342895
-
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines
-
Ling YH, Liebes L, Jiang JD, et al. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. Clinical Cancer Research. 2003;9(3):1145-1154.
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.3
, pp. 1145-1154
-
-
Ling, Y.H.1
Liebes, L.2
Jiang, J.D.3
-
117
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher BA, Ara G, Herbst R, Palombella VJ, Adams J. The proteasome inhibitor PS-341 in cancer therapy. Clinical Cancer Research. 1999;5(9):2638-2645.
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.9
, pp. 2638-2645
-
-
Teicher, B.A.1
Ara, G.2
Herbst, R.3
Palombella, V.J.4
Adams, J.5
-
118
-
-
0035328584
-
Enhanced chemosensitivity to CPT- 11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-kappa B inhibition
-
Cusack JC, Liu R, Houston M, et al. Enhanced chemosensitivity to CPT- 11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-kappa B inhibition. Cancer Research. 2001;61(9):3535-3540.
-
(2001)
Cancer Research
, vol.61
, Issue.9
, pp. 3535-3540
-
-
Cusack, J.C.1
Liu, R.2
Houston, M.3
-
119
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, et al. Proteasome inhibitors: A novel class of potent and effective antitumor agents. Cancer Research. 1999;59(11):2615-2622.
-
(1999)
Cancer Research
, vol.59
, Issue.11
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
-
120
-
-
0034193276
-
Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs
-
Ogiso Y, Tomida A, Lei SH, Omura S, Tsuruo T. Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs. Cancer Research. 2000;60(9):2429-2434.
-
(2000)
Cancer Research
, vol.60
, Issue.9
, pp. 2429-2434
-
-
Ogiso, Y.1
Tomida, A.2
Lei, S.H.3
Omura, S.4
Tsuruo, T.5
-
121
-
-
33947356281
-
Bortezomib-mediated 26S proteasome inhibition causes cell-cycle arrest and induces apoptosis in CD-30(+) anaplastic large cell lymphoma
-
Bonvini P, Zorzi E, Basso G, Rosolen A. Bortezomib-mediated 26S proteasome inhibition causes cell-cycle arrest and induces apoptosis in CD-30(+) anaplastic large cell lymphoma. Leukemia. 2007;21(4): 838-842.
-
(2007)
Leukemia
, vol.21
, Issue.4
, pp. 838-842
-
-
Bonvini, P.1
Zorzi, E.2
Basso, G.3
Rosolen, A.4
-
122
-
-
84901172464
-
Overexpression of proteasome beta 5 subunit increases amount of assembled proteasome and confers ameliorated response to oxidative stress and higher survival rates
-
Chondrogianni N, Gonos ES. Overexpression of proteasome beta 5 subunit increases amount of assembled proteasome and confers ameliorated response to oxidative stress and higher survival rates. Febs Journal. 2005;272:151.
-
(2005)
Febs Journal
, vol.272
, pp. 151
-
-
Chondrogianni, N.1
Gonos, E.S.2
-
123
-
-
0037342895
-
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines
-
Ling YH, Liebes L, Jiang JD, et al. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. Clinical Cancer Research. 2003;9(3):1145-1154.
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.3
, pp. 1145-1154
-
-
Ling, Y.H.1
Liebes, L.2
Jiang, J.D.3
-
124
-
-
47949089799
-
Point mutation of the proteasome beta 5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic lymphoma/leukemia line
-
Lu SQ, Yang JM, Song XM, et al. Point mutation of the proteasome beta 5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic lymphoma/leukemia line. Journal of Pharmacology and Experimental Therapeutics. 2008;326(2):423-431.
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.326
, Issue.2
, pp. 423-431
-
-
Lu, S.Q.1
Yang, J.M.2
Song, X.M.3
-
125
-
-
53049106912
-
Molecular basis of bortezomib resistance: Proteasome subunit beta 5 (PSMB5) gene mutation and overexpression of PSMB5 protein
-
Oerlemans R, Franke NE, Assaraf YG, et al. Molecular basis of bortezomib resistance: proteasome subunit beta 5 (PSMB5) gene mutation and overexpression of PSMB5 protein. Blood. 2008;112(6):2489-2499.
-
(2008)
Blood
, vol.112
, Issue.6
, pp. 2489-2499
-
-
Oerlemans, R.1
Franke, N.E.2
Assaraf, Y.G.3
|