메뉴 건너뛰기




Volumn 34, Issue 26, 2014, Pages 8749-8760

RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environment

Author keywords

Entorhinal cortex; Interleukin1 beta; Jnk; Neuroinflammation; p38mapk; Synaptic transmission

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 84903202395     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0141-14.2014     Document Type: Article
Times cited : (46)

References (84)
  • 2
    • 77953608972 scopus 로고    scopus 로고
    • JNK inhibition and inflammation after cerebral ischemia
    • CrossRef Medline
    • Benakis C., Bonny C, Hirt L (2010) JNK inhibition and inflammation after cerebral ischemia. Brain Behav Immun 24:800-811. CrossRef Medline
    • (2010) Brain Behav Immun , vol.24 , pp. 800-811
    • Benakis, C.1    Bonny, C.2    Hirt, L.3
  • 3
    • 0026134421 scopus 로고
    • Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections
    • Medline
    • Braak H., Braak E (1991) Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections. Brain Pathol 1:213-216. Medline
    • (1991) Brain Pathol , vol.1 , pp. 213-216
    • Braak, H.1    Braak, E.2
  • 4
  • 5
    • 38349143353 scopus 로고    scopus 로고
    • RAGE: A potential target for Abeta-mediated cellular perturbation in Alzheimer's disease
    • CrossRef Medline
    • Chen X., Walker DG, Schmidt AM, Arancio O, Lue LF, Yan SD (2007) RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease. Curr Mol Med 7:735-742. CrossRef Medline
    • (2007) Curr Mol Med , vol.7 , pp. 735-742
    • Chen, X.1    Walker, D.G.2    Schmidt, A.M.3    Arancio, O.4    Lue, L.F.5    Yan, S.D.6
  • 7
    • 34848893886 scopus 로고    scopus 로고
    • Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats
    • CrossRef Medline
    • Clarke J., Thornell A, Corbett D, Soininen H, Hiltunen M, Jolkkonen J (2007) Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats. Eur J Neurosci 26:1845-1852. CrossRef Medline
    • (2007) Eur J Neurosci , vol.26 , pp. 1845-1852
    • Clarke, J.1    Thornell, A.2    Corbett, D.3    Soininen, H.4    Hiltunen, M.5    Jolkkonen, J.6
  • 8
    • 0033057788 scopus 로고    scopus 로고
    • The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro
    • CrossRef Medline
    • Coogan A. N, O'Neill LA, O'Connor JJ (1999) The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro. Neuroscience 93:57-69. CrossRef Medline
    • (1999) Neuroscience , vol.93 , pp. 57-69
    • Coogan, A.N.1    O'Neill, L.A.2    O'Connor, J.J.3
  • 9
    • 0030809128 scopus 로고    scopus 로고
    • Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments
    • CrossRef Medline
    • Cullen W. K, Suh YH, Anwyl R, Rowan MJ (1997) Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments. Neuroreport 8:3213-3217. CrossRef Medline
    • (1997) Neuroreport , vol.8 , pp. 3213-3217
    • Cullen, W.K.1    Suh, Y.H.2    Anwyl, R.3    Rowan, M.J.4
  • 10
    • 0037426609 scopus 로고    scopus 로고
    • A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitro
    • CrossRef Medline
    • Curran B. P, Murray HJ, O'Connor JJ (2003) A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1beta and long-term depression in the rat dentate gyrus in vitro. Neuroscience 118:347-357. CrossRef Medline
    • (2003) Neuroscience , vol.118 , pp. 347-357
    • Curran, B.P.1    Murray, H.J.2    O'Connor, J.J.3
  • 11
    • 20444430784 scopus 로고    scopus 로고
    • Is Alzheimer's disease preceded by neurodegeneration or cerebral hypoperfusion?
    • CrossRef Medline
    • de la Torre J. C (2005) Is Alzheimer's disease preceded by neurodegeneration or cerebral hypoperfusion? Ann Neurol 57:783-784. CrossRef Medline
    • (2005) Ann Neurol , vol.57 , pp. 783-784
    • de la Torre, J.C.1
  • 12
    • 47849112648 scopus 로고    scopus 로고
    • Alzheimer's disease prevalence can be lowered with non-invasive testing
    • Medline
    • de la Torre J. C (2008) Alzheimer's disease prevalence can be lowered with non-invasive testing. J Alzheimers Dis 14:353-359. Medline
    • (2008) J Alzheimers Dis , vol.14 , pp. 353-359
    • de la Torre, J.C.1
  • 14
    • 0000920292 scopus 로고    scopus 로고
    • Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
    • CrossRef Medline
    • Du Yan S., Zhu H, Fu J, Yan SF, Roher A, Tourtellotte WW, Rajavashisth T, Chen X., Godman GC, Stern D, Schmidt AM (1997) Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease. Proc Natl Acad Sci U S A 94: 5296-5301. CrossRef Medline
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5296-5301
    • Du Yan, S.1    Zhu, H.2    Fu, J.3    Yan, S.F.4    Roher, A.5    Tourtellotte, W.W.6    Rajavashisth, T.7    Chen, X.8    Godman, G.C.9    Stern, D.10    Schmidt, A.M.11
  • 15
    • 77951647591 scopus 로고    scopus 로고
    • RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
    • CrossRef Medline
    • Fang F., Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS (2010) RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J 24:1043-1055. CrossRef Medline
    • (2010) FASEB J , vol.24 , pp. 1043-1055
    • Fang, F.1    Lue, L.F.2    Yan, S.3    Xu, H.4    Luddy, J.S.5    Chen, D.6    Walker, D.G.7    Stern, D.M.8    Yan, S.9    Schmidt, A.M.10    Chen, J.X.11    Yan, S.S.12
  • 16
    • 0038584865 scopus 로고    scopus 로고
    • A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neurons
    • CrossRef Medline
    • Fogarty M. P, Downer EJ, Campbell V (2003) A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neurons. Biochem J 371:789-798. CrossRef Medline
    • (2003) Biochem J , vol.371 , pp. 789-798
    • Fogarty, M.P.1    Downer, E.J.2    Campbell, V.3
  • 17
    • 33644649803 scopus 로고    scopus 로고
    • Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
    • CrossRef Medline
    • Girouard H., Iadecola C (2006) Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 100: 328-335. CrossRef Medline
    • (2006) J Appl Physiol , vol.100 , pp. 328-335
    • Girouard, H.1    Iadecola, C.2
  • 18
    • 80052400687 scopus 로고    scopus 로고
    • Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American Stroke Association
    • American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia. CrossRef Medline
    • Gorelick P. B, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer L. J, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C., Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson P. M, Roman GC, et al.; American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia (2011) Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 42:2672-2713. CrossRef Medline
    • (2011) Stroke , vol.42 , pp. 2672-2713
    • Gorelick, P.B.1    Scuteri, A.2    Black, S.E.3    Decarli, C.4    Greenberg, S.M.5    Iadecola, C.6    Launer, L.J.7    Laurent, S.8    Lopez, O.L.9    Nyenhuis, D.10    Petersen, R.C.11    Schneider, J.A.12    Tzourio, C.13    Arnett, D.K.14    Bennett, D.A.15    Chui, H.C.16    Higashida, R.T.17    Lindquist, R.18    Nilsson, P.M.19    Roman, G.C.20    more..
  • 20
    • 76849087262 scopus 로고    scopus 로고
    • Mechanism of S100b release from rat cortical slices determined under basal and stimulated conditions
    • CrossRef Medline
    • Gürsoy M., Büyükuysal RL (2010) Mechanism of S100b release from rat cortical slices determined under basal and stimulated conditions. Neurochem Res 35:429-436. CrossRef Medline
    • (2010) Neurochem Res , vol.35 , pp. 429-436
    • Gürsoy, M.1    Büyükuysal, R.L.2
  • 22
    • 84856457578 scopus 로고    scopus 로고
    • Ischemic cerebral damage: An appraisal of synaptic failure
    • CrossRef Medline
    • Hofmeijer J., van Putten MJ (2012) Ischemic cerebral damage: an appraisal of synaptic failure. Stroke 43:607-615. CrossRef Medline
    • (2012) Stroke , vol.43 , pp. 607-615
    • Hofmeijer, J.1    van Putten, M.J.2
  • 23
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
    • CrossRef Medline
    • Hsieh H., Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R (2006) AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52:831-843. CrossRef Medline
    • (2006) Neuron , vol.52 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 24
    • 0037207531 scopus 로고    scopus 로고
    • Interleukin-1beta abrogates long-term depression of hippocampal CA1 synaptic transmission
    • CrossRef Medline
    • Ikegaya Y., Delcroix I, Iwakura Y, Matsuki N, Nishiyama N (2003) Interleukin-1beta abrogates long-term depression of hippocampal CA1 synaptic transmission. Synapse 47:54-57. CrossRef Medline
    • (2003) Synapse , vol.47 , pp. 54-57
    • Ikegaya, Y.1    Delcroix, I.2    Iwakura, Y.3    Matsuki, N.4    Nishiyama, N.5
  • 25
    • 0036959437 scopus 로고    scopus 로고
    • beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase
    • CrossRef Medline
    • Jang J. H, Surh YJ (2002) beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase. Ann N Y Acad Sci 973:228-236. CrossRef Medline
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 228-236
    • Jang, J.H.1    Surh, Y.J.2
  • 26
    • 0038482127 scopus 로고    scopus 로고
    • Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus
    • CrossRef Medline
    • Kelly A., Vereker E, Nolan Y, Brady M, Barry C, Loscher CE, Mills KH, Lynch MA (2003) Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus. J Biol Chem 278:19453-19462. CrossRef Medline
    • (2003) J Biol Chem , vol.278 , pp. 19453-19462
    • Kelly, A.1    Vereker, E.2    Nolan, Y.3    Brady, M.4    Barry, C.5    Loscher, C.E.6    Mills, K.H.7    Lynch, M.A.8
  • 27
    • 84872176512 scopus 로고    scopus 로고
    • Microglia: New roles for the synaptic stripper
    • CrossRef Medline
    • Kettenmann H., Kirchhoff F, Verkhratsky A (2013) Microglia: new roles for the synaptic stripper. Neuron 77:10-18. CrossRef Medline
    • (2013) Neuron , vol.77 , pp. 10-18
    • Kettenmann, H.1    Kirchhoff, F.2    Verkhratsky, A.3
  • 32
    • 74449093355 scopus 로고    scopus 로고
    • Possible involvement of NO/NOS signaling in hippocampal amyloid-beta production induced by transient focal cerebral ischemia in aged rats
    • CrossRef Medline
    • Li S., Wang W, Wang C, Tang YY (2010) Possible involvement of NO/NOS signaling in hippocampal amyloid-beta production induced by transient focal cerebral ischemia in aged rats. Neurosci Lett 470:106-110. CrossRef Medline
    • (2010) Neurosci Lett , vol.470 , pp. 106-110
    • Li, S.1    Wang, W.2    Wang, C.3    Tang, Y.Y.4
  • 34
    • 79851509606 scopus 로고    scopus 로고
    • Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: Involvement of anti-oxidation and anti-inflammation through nuclear transcription factor kappaappaB signaling pathway
    • CrossRef Medline
    • Liu R., Zhang L, Lan X, Li L, Zhang TT, Sun JH, DuGH (2011) Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor kappaappaB signaling pathway. Neuroscience 176:408-419. CrossRef Medline
    • (2011) Neuroscience , vol.176 , pp. 408-419
    • Liu, R.1    Zhang, L.2    Lan, X.3    Li, L.4    Zhang, T.T.5    Sun, J.H.6    Du, G.H.7
  • 36
    • 0034840664 scopus 로고    scopus 로고
    • Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: Identification of a cellular activation mechanism
    • CrossRef Medline
    • Lue L. F, Walker DG, Brachova L, Beach TG, Rogers J, Schmidt AM, Stern DM, Yan S. D (2001) Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp Neurol 171:29-45. CrossRef Medline
    • (2001) Exp Neurol , vol.171 , pp. 29-45
    • Lue, L.F.1    Walker, D.G.2    Brachova, L.3    Beach, T.G.4    Rogers, J.5    Schmidt, A.M.6    Stern, D.M.7    Yan, S.D.8
  • 37
    • 59649092943 scopus 로고    scopus 로고
    • Intracellular Zn2+accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia
    • CrossRef Medline
    • Medvedeva Y. V, Lin B, Shuttleworth CW, Weiss JH (2009) Intracellular Zn2+accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia. J Neurosci 29:1105-1114. CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 1105-1114
    • Medvedeva, Y.V.1    Lin, B.2    Shuttleworth, C.W.3    Weiss, J.H.4
  • 38
    • 0041344592 scopus 로고    scopus 로고
    • Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: A role for interleukin-1beta?
    • CrossRef Medline
    • Minogue A. M, Schmid AW, Fogarty MP, Moore AC, Campbell VA, Herron CE, Lynch MA (2003) Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta? J Biol Chem 278:27971-27980. CrossRef Medline
    • (2003) J Biol Chem , vol.278 , pp. 27971-27980
    • Minogue, A.M.1    Schmid, A.W.2    Fogarty, M.P.3    Moore, A.C.4    Campbell, V.A.5    Herron, C.E.6    Lynch, M.A.7
  • 39
    • 0035478618 scopus 로고    scopus 로고
    • Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand
    • Medline
    • Morishima Y., Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, Davis RJ, Shirasaki Y., Greenberg ME (2001) Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. J Neurosci 21:7551-7560. Medline
    • (2001) J Neurosci , vol.21 , pp. 7551-7560
    • Morishima, Y.1    Gotoh, Y.2    Zieg, J.3    Barrett, T.4    Takano, H.5    Flavell, R.6    Davis, R.J.7    Shirasaki, Y.8    Greenberg, M.E.9
  • 40
    • 84859157336 scopus 로고    scopus 로고
    • A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays
    • CrossRef Medline
    • Mozes E., Hunya A, Posa A, Penke B, Datki Z (2012) A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays. Brain Res Bull 87:521-525. CrossRef Medline
    • (2012) Brain Res Bull , vol.87 , pp. 521-525
    • Mozes, E.1    Hunya, A.2    Posa, A.3    Penke, B.4    Datki, Z.5
  • 41
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • Medline
    • Mucke L., Masliah E, Yu GQ, Mallory M, Rockenstein EM, Tatsuno G, Hu K, Kholodenko D., Johnson-Wood K, McConlogue L (2000) High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci 20:4050-4058. Medline
    • (2000) J Neurosci , vol.20 , pp. 4050-4058
    • Mucke, L.1    Masliah, E.2    Yu, G.Q.3    Mallory, M.4    Rockenstein, E.M.5    Tatsuno, G.6    Hu, K.7    Kholodenko, D.8    Johnson-Wood, K.9    McConlogue, L.10
  • 43
    • 41549089757 scopus 로고    scopus 로고
    • Receptor for advanced glycation end product-dependent activation of p38 mitogenactivated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction
    • CrossRef Medline
    • Origlia N., Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt A. M, Arancio O, Yan SD, Domenici L (2008) Receptor for advanced glycation end product-dependent activation of p38 mitogenactivated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. J Neurosci 28:3521-3530. CrossRef Medline
    • (2008) J Neurosci , vol.28 , pp. 3521-3530
    • Origlia, N.1    Righi, M.2    Capsoni, S.3    Cattaneo, A.4    Fang, F.5    Stern, D.M.6    Chen, J.X.7    Schmidt, A.M.8    Arancio, O.9    Yan, S.D.10    Domenici, L.11
  • 44
    • 67650882249 scopus 로고    scopus 로고
    • Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: The role of RAGE
    • CrossRef Medline
    • Origlia N., Capsoni S, Cattaneo A, Fang F, Arancio O, Yan SD, Domenici L (2009a) Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE. J Alzheimers Dis 17:59-68. CrossRef Medline
    • (2009) J Alzheimers Dis , vol.17 , pp. 59-68
    • Origlia, N.1    Capsoni, S.2    Cattaneo, A.3    Fang, F.4    Arancio, O.5    Yan, S.D.6    Domenici, L.7
  • 45
    • 70849085456 scopus 로고    scopus 로고
    • MAPK, beta-amyloid and synaptic dysfunction: The role of RAGE
    • CrossRef Medline
    • Origlia N., Arancio O, Domenici L, Yan SS (2009b) MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE. Expert Rev Neurother 9:1635-1645. CrossRef Medline
    • (2009) Expert Rev Neurother , vol.9 , pp. 1635-1645
    • Origlia, N.1    Arancio, O.2    Domenici, L.3    Yan, S.S.4
  • 46
    • 77956104594 scopus 로고    scopus 로고
    • Microglial receptor for advanced glycation end productdependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex
    • CrossRef Medline
    • Origlia N., Bonadonna C, Rosellini A, Leznik E, Arancio O, Yan SS, Domenici L (2010) Microglial receptor for advanced glycation end productdependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex. J Neurosci 30:11414-11425. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 11414-11425
    • Origlia, N.1    Bonadonna, C.2    Rosellini, A.3    Leznik, E.4    Arancio, O.5    Yan, S.S.6    Domenici, L.7
  • 48
    • 13844299709 scopus 로고    scopus 로고
    • Presenilin attenuates receptor-mediated signaling and synaptic function
    • CrossRef Medline
    • Parent A. T, Barnes NY, Taniguchi Y, Thinakaran G, Sisodia SS (2005) Presenilin attenuates receptor-mediated signaling and synaptic function. J Neurosci 25:1540-1549. CrossRef Medline
    • (2005) J Neurosci , vol.25 , pp. 1540-1549
    • Parent, A.T.1    Barnes, N.Y.2    Taniguchi, Y.3    Thinakaran, G.4    Sisodia, S.S.5
  • 50
    • 37549011413 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia
    • CrossRef Medline
    • Pichiule P., Chavez JC, Schmidt AM, Vannucci SJ (2007) Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia. J Biol Chem 282: 36330-36340. CrossRef Medline
    • (2007) J Biol Chem , vol.282 , pp. 36330-36340
    • Pichiule, P.1    Chavez, J.C.2    Schmidt, A.M.3    Vannucci, S.J.4
  • 51
    • 84870493605 scopus 로고    scopus 로고
    • Effects of mild chronic cerebral hypoperfusion and early amyloid pathology on spatial learning and the cellular innate immune response in mice
    • CrossRef Medline
    • Pimentel-Coelho P. M, Michaud JP, Rivest S (2013) Effects of mild chronic cerebral hypoperfusion and early amyloid pathology on spatial learning and the cellular innate immune response in mice. Neurobiol Aging 34: 679-693. CrossRef Medline
    • (2013) Neurobiol Aging , vol.34 , pp. 679-693
    • Pimentel-Coelho, P.M.1    Michaud, J.P.2    Rivest, S.3
  • 54
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • CrossRef Medline
    • Schmidt A. M, Yan SD, Yan SF, Stern DM (2001) The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 108:949-955. CrossRef Medline
    • (2001) J Clin Invest , vol.108 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 56
    • 34249900204 scopus 로고    scopus 로고
    • Retinoic acids acting through retinoid receptors protect hippocampal neurons from oxygen-glucose deprivation-mediated cell death by inhibition of c-jun-N-terminal kinase and p38 mitogen-activated protein kinase
    • CrossRef Medline
    • Shinozaki Y., Sato Y, Koizumi S, Ohno Y, Nagao T, Inoue K (2007) Retinoic acids acting through retinoid receptors protect hippocampal neurons from oxygen-glucose deprivation-mediated cell death by inhibition of c-jun-N-terminal kinase and p38 mitogen-activated protein kinase. Neuroscience 147:153-163. CrossRef Medline
    • (2007) Neuroscience , vol.147 , pp. 153-163
    • Shinozaki, Y.1    Sato, Y.2    Koizumi, S.3    Ohno, Y.4    Nagao, T.5    Inoue, K.6
  • 58
    • 1342286733 scopus 로고    scopus 로고
    • Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction
    • CrossRef Medline
    • Simm A., Casselmann C, Schubert A, Hofmann S, Reimann A, Silber RE (2004) Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction. Exp Gerontol 39:407-413. CrossRef Medline
    • (2004) Exp Gerontol , vol.39 , pp. 407-413
    • Simm, A.1    Casselmann, C.2    Schubert, A.3    Hofmann, S.4    Reimann, A.5    Silber, R.E.6
  • 67
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • CrossRef Medline
    • Vitolo O. V, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M (2002) Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc Natl Acad Sci U S A 99:13217-13221. CrossRef Medline
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 68
    • 65249157852 scopus 로고    scopus 로고
    • Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
    • CrossRef Medline
    • Wake H., Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci 29:3974-3980. CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 3974-3980
    • Wake, H.1    Moorhouse, A.J.2    Jinno, S.3    Kohsaka, S.4    Nabekura, J.5
  • 69
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
    • CrossRef Medline
    • Walsh D. M, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ (2002) Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416:535-539. CrossRef Medline
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 70
    • 1842610852 scopus 로고    scopus 로고
    • Block of longterm potentiation by naturally secreted and synthetic amyloid betapeptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogenactivated protein kinase as well as metabotropic glutamate receptor type 5
    • Medline
    • Wang Q., Walsh DM, Rowan MJ, Selkoe DJ, Anwyl R (2004) Block of longterm potentiation by naturally secreted and synthetic amyloid betapeptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogenactivated protein kinase as well as metabotropic glutamate receptor type 5. J Neurosci 24:3370-3378. Medline
    • (2004) J Neurosci , vol.24 , pp. 3370-3378
    • Wang, Q.1    Walsh, D.M.2    Rowan, M.J.3    Selkoe, D.J.4    Anwyl, R.5
  • 71
    • 3042798841 scopus 로고    scopus 로고
    • Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
    • CrossRef Medline
    • Wang Q., Rowan MJ, AnwylR (2004b) Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J Neurosci 24:6049-6056. CrossRef Medline
    • (2004) J Neurosci , vol.24 , pp. 6049-6056
    • Wang, Q.1    Rowan, M.J.2    Anwyl, R.3
  • 73
    • 0036707528 scopus 로고    scopus 로고
    • Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis
    • CrossRef Medline
    • Wei W., Norton DD, Wang X, Kusiak JW (2002) Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis. Brain 125:2036-2043. CrossRef Medline
    • (2002) Brain , vol.125 , pp. 2036-2043
    • Wei, W.1    Norton, D.D.2    Wang, X.3    Kusiak, J.W.4
  • 74
    • 0024398259 scopus 로고
    • Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region
    • CrossRef Medline
    • Witter M. P, Groenewegen HJ, Lopes da Silva FH, Lohman AH (1989) Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region. Prog Neurobiol 33:161-253. CrossRef Medline
    • (1989) Prog Neurobiol , vol.33 , pp. 161-253
    • Witter, M.P.1    Groenewegen, H.J.2    da Silva Lopes, F.H.3    Lohman, A.H.4
  • 75
    • 0029076397 scopus 로고
    • Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide
    • CrossRef Medline
    • Yan S. D, Yan SF, Chen X, Fu J, Chen M, Kuppusamy P, Smith MA, Perry G, Godman G. C, Nawroth P, et al. (1995) Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat Med 1:693-699. CrossRef Medline
    • (1995) Nat Med , vol.1 , pp. 693-699
    • Yan, S.D.1    Yan, S.F.2    Chen, X.3    Fu, J.4    Chen, M.5    Kuppusamy, P.6    Smith, M.A.7    Perry, G.8    Godman, G.C.9    Nawroth, P.10
  • 77
    • 33847051684 scopus 로고    scopus 로고
    • Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Abeta interaction
    • CrossRef Medline
    • Yan Y., Liu Y, Sorci M, Belfort G, Lustbader JW, Yan SS, Wang C (2007) Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Abeta interaction. Biochemistry 46:1724-1731. CrossRef Medline
    • (2007) Biochemistry , vol.46 , pp. 1724-1731
    • Yan, Y.1    Liu, Y.2    Sorci, M.3    Belfort, G.4    Lustbader, J.W.5    Yan, S.S.6    Wang, C.7
  • 78
    • 0033582341 scopus 로고    scopus 로고
    • Effects of an interleukin-1beta analogue [Lys-D-Pro-Thr], on incomplete cerebral ischemia-induced inhibition of long-term potentiation in rat hippocampal neurons in vivo
    • CrossRef Medline
    • Yoshioka M., Itoh Y, Mori K, Ueno K, Matsumoto M, Togashi H (1999) Effects of an interleukin-1beta analogue [Lys-D-Pro-Thr], on incomplete cerebral ischemia-induced inhibition of long-term potentiation in rat hippocampal neurons in vivo. Neurosci Lett 261:171-174. CrossRef Medline
    • (1999) Neurosci Lett , vol.261 , pp. 171-174
    • Yoshioka, M.1    Itoh, Y.2    Mori, K.3    Ueno, K.4    Matsumoto, M.5    Togashi, H.6
  • 80
    • 0030848729 scopus 로고    scopus 로고
    • Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein
    • Medline
    • Zhang F., Eckman C, Younkin S, Hsiao KK, Iadecola C (1997) Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein. J Neurosci 17:7655-7661. Medline
    • (1997) J Neurosci , vol.17 , pp. 7655-7661
    • Zhang, F.1    Eckman, C.2    Younkin, S.3    Hsiao, K.K.4    Iadecola, C.5
  • 81
    • 84897401619 scopus 로고    scopus 로고
    • Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase
    • CrossRef Medline
    • Zhang J., Malik A, Choi HB, Ko RW, Dissing-Olesen L, MacVicar BA (2014) Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase. Neuron 82:195-207. CrossRef Medline
    • (2014) Neuron , vol.82 , pp. 195-207
    • Zhang, J.1    Malik, A.2    Choi, H.B.3    Ko, R.W.4    Dissing-Olesen, L.5    McVicar, B.A.6
  • 82
    • 84896718185 scopus 로고    scopus 로고
    • Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model
    • CrossRef Medline
    • Zhang T., Wang H, Li Q, Huang J, Sun X (2014) Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model. Neuroscience 263:130-137. CrossRef Medline
    • (2014) Neuroscience , vol.263 , pp. 130-137
    • Zhang, T.1    Wang, H.2    Li, Q.3    Huang, J.4    Sun, X.5
  • 83
    • 34249727115 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation
    • CrossRef Medline
    • Zhang X., Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW (2007) Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. J Biol Chem 282:10873-10880. CrossRef Medline
    • (2007) J Biol Chem , vol.282 , pp. 10873-10880
    • Zhang, X.1    Zhou, K.2    Wang, R.3    Cui, J.4    Lipton, S.A.5    Liao, F.F.6    Xu, H.7    Zhang, Y.W.8
  • 84
    • 67349164281 scopus 로고    scopus 로고
    • Upregulation of BACE1 and beta-amyloid protein mediated by chronic cerebral hypoperfusion contributes to cognitive impairment and pathogenesis of Alzheimer's disease
    • CrossRef Medline
    • Zhiyou C., Yong Y, Shanquan S, Jun Z, Liangguo H, Ling Y, Jieying L (2009) Upregulation of BACE1 and beta-amyloid protein mediated by chronic cerebral hypoperfusion contributes to cognitive impairment and pathogenesis of Alzheimer's disease. Neurochem Res 34:1226-1235. CrossRef Medline
    • (2009) Neurochem Res , vol.34 , pp. 1226-1235
    • Zhiyou, C.1    Yong, Y.2    Shanquan, S.3    Jun, Z.4    Liangguo, H.5    Ling, Y.6    Jieying, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.