Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-β-mediated cortical synaptic dysfunction

Journal of Neuroscience

Volumn 28, Issue 13, 2008, Pages 3521-3530

  Origlia, Nicola ^a   Righi, Massimo ^b   Capsoni, Simona ^c   Cattaneo, Antonino ^d   Fang, Fang ^e   Stern, David M ^f   Chen, John Xi ^g   Schmidt, Ann Marie ^e   Arancio, Ottavio ^e   Shi, Du Yan ^e   Domenici, Luciano ^a,h  

^a CNR   (Italy)

^b SISSA   (Italy)

^c Lay Line Genomics SpA   (Italy)

^d EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^e Howard Hughes Medical Institute   (United States)

^f UNIVERSITY OF CINCINNATI   (United States)

^g Harvey Cushing Institutes of Neuroscience   (United States)

^h UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

Alzheimer's disease; Amyloid ; Entorhinal cortex; LTP; p38 MAPK; Protein; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN; BLOCKING ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGOMER; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENTORHINAL CORTEX; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; AMYLOID BETA-PROTEIN; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ENTORHINAL CORTEX; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LONG-TERM POTENTIATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL INHIBITION; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; RECEPTORS, IMMUNOLOGIC; SYNAPSES;

EID: 41549089757     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0204-08.2008     Document Type: Article

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