RAGE expression is up-regulated in human cerebral ischemia and pMCAO rats

Neuroscience Letters

Volumn 445, Issue 1, 2008, Pages 117-121

  Zhai, Dong Xu ^a   Kong, Qing Fei ^a   Xu, Wang Shu ^a   Bai, Sha Sha ^a   Peng, Hai Sheng ^a   Zhao, Kai ^a   Li, Guo Zhong ^a   Wang, Dan Dan ^a   Sun, Bo ^a   Wang, Jing Hua ^a   Wang, Guang You ^a   Li, Hu Lun ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Brain ischemia; OGD; PC12 cells; pMCAO; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANTIBODY; GLUCOSE; OXYGEN;

ADULT; AGED; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOPSY TECHNIQUE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DAMAGE; CELL STRAIN; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HEMISPHERE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ADULT; AGED; ANIMALS; BRAIN ISCHEMIA; CELL COUNT; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MIDDLE AGED; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; TIME FACTORS; UP-REGULATION;

EID: 52949154618     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.08.077     Document Type: Article

References (25)

1. Abu Raya S., Trembovler V., Shohami E., and Lazarovici P. A tissue culture ischemic device to study eicosanoid release by pheochromocytoma PC12 cultures. J. Neurosci. Methods 50 (1993) 197-203
2. Brett J., Schmidt A.M., Yan S.D., Zou Y.S., Weidman E., Pinsky D., Nowygrod R., Neeper M., Przysiecki C., Shaw A., Migheli A., and Stern D. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am. J. Pathol. 143 (1993) 1699-1712
3. Deane R., Du Yan S., Submamaryan R.K., LaRue B., Jovanovic S., Hogg E., Welch D., Manness L., Lin C., Yu J., Zhu H., Ghiso J., Frangione B., Stern A., Schmidt A.M., Armstrong D.L., Arnold B., Liliensiek B., Nawroth P., Hofman F., Kindy M., Stern D., and Zlokovic B. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat. Med. 9 (2003) 907-913
4. Foerch C., Otto B., Singer O.C., Neumann-Haefelin T., Yan B., Berkefeld J., Steinmetz H., and Sitzer M. Serum S100B predicts a malignant course of infarction in patients with acute middle cerebral artery occlusion. Stroke 35 (2004) 2160-2164
5. George Paxinos C.W. The Rat Brain in Stereotaxic Coordinates (1997), Academic Press, Sydney
6. Gonzalez-Perez O., Gonzalez-Castaneda R.E., Huerta M., Luquin S., Gomez-Pinedo U., Sanchez-Almaraz E., Navarro-Ruiz A., and Garcia-Estrada J. Beneficial effects of alpha-lipoic acid plus vitamin E on neurological deficit, reactive gliosis and neuronal remodeling in the penumbra of the ischemic rat brain. Neurosci. Lett. 321 (2002) 100-104
7. Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., Avila C., Kambham N., Bierhaus A., Nawroth P., Neurath M.F., Slattery T., Beach D., McClary J., Nagashima M., Morser J., Stern D., and Schmidt A.M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97 (1999) 889-901
8. Hori O., Brett J., Slattery T., Cao R., Zhang J., Chen J., Nagashima M., Lundh E.R., Vijay S., Nitecki D., Morser J., Stern D., and Schmidt A.M. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J. Biol. Chem. 270 (1995) 25752-25761
9. Kim J.B., Sig Choi J., Yu Y.M., Nam K., Piao C.S., Kim S.W., Lee M.H., Han P.L., Park J.S., Lee J.K., and HMGB1. a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J. Neurosci. 26 (2006) 6413-6421
10. Kondo T., Reaume A.G., Huang T.T., Carlson E., Murakami K., Chen S.F., Hoffman E.K., Scott R.W., Epstein C.J., and Chan P.H. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J. Neurosci. 17 (1997) 4180-4189
11. Li G.Z., Zhong D., Yang L.M., Sun B., Zhong Z.H., Yin Y.H., Cheng J., Yan B.B., and Li H.L. Expression of interleukin-17 in ischemic brain tissue. Scand. J. Immunol. 62 (2005) 481-486
12. Lue L.F., Walker D.G., Brachova L., Beach T.G., Rogers J., Schmidt A.M., Stern D.M., and Yan S.D. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp. Neurol. 171 (2001) 29-45
13. Lutterloh E.C., and Opal S.M. Antibodies against RAGE in sepsis and inflammation: implications for therapy. Expert Opin. Pharmacother. 8 (2007) 1193-1196
14. Ma L., Carter R.J., Morton A.J., and Nicholson L.F. RAGE is expressed in pyramidal cells of the hippocampus following moderate hypoxic-ischemic brain injury in rats. Brain Res. 966 (2003) 167-174
15. Neeper M., Schmidt A.M., Brett J., Yan S.D., Wang F., Pan Y.C., Elliston K., Stern D., and Shaw A. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J. Biol. Chem. 267 (1992) 14998-15004
16. Pichiule P., Chavez J.C., Schmidt A.M., and Vannucci S.J. Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia. J. Biol. Chem. 282 (2007) 36330-36340
17. Popa-Wagner A., Schroder E., Walker L.C., and Kessler C. beta-Amyloid precursor protein and ss-amyloid peptide immunoreactivity in the rat brain after middle cerebral artery occlusion: effect of age. Stroke 29 (1998) 2196-2202
18. Riuzzi F., Sorci G., and Donato R. The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in vivo. J. Biol. Chem. 281 (2006) 8242-8253
19. Sorci G., Riuzzi F., Agneletti A.L., Marchetti C., and Donato R. S100B causes apoptosis in a myoblast cell line in a RAGE-independent manner. J. Cell. Physiol. 199 (2004) 274-283
20. Sousa M.M., Du Yan S., Fernandes R., Guimaraes A., Stern D., and Saraiva M.J. Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways. J. Neurosci. 21 (2001) 7576-7586
21. Sparatore B., Pedrazzi M., Passalacqua M., Gaggero D., Patrone M., Pontremoli S., and Melloni E. Stimulation of erythroleukaemia cell differentiation by extracellular high-mobility group-box protein 1 is independent of the receptor for advanced glycation end-products. Biochem. J. 363 (2002) 529-535
22. Wang Q., Tang X.N., and Yenari M.A. The inflammatory response in stroke. J. Neuroimmunol. 184 (2007) 53-68
23. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., and Schmidt A.M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382 (1996) 685-691
24. Yepes M., Sandkvist M., Wong M.K., Coleman T.A., Smith E., Cohan S.L., and Lawrence D.A. Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis. Blood 96 (2000) 569-576
25. Zimmerman G.A., Meistrell 3rd M., Bloom O., Cockroft K.M., Bianchi M., Risucci D., Broome J., Farmer P., Cerami A., and Vlassara H. Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 3744-3748