Defective cholesterol traffic and neuronal differentiation in neural stem cells of Niemann-Pick type C disease improved by valproic acid, a histone deacetylase inhibitor

Biochemical and Biophysical Research Communications

Volumn 360, Issue 3, 2007, Pages 593-599

  Kim, Sun Jung ^a,b   Lee, Bong Hee ^c   Lee, Yong Soon ^a,b   Kang, Kyung Sun ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Gachon University College of Medicine   (South Korea)

Author keywords

A histone deacetylase inhibitor; Neural stem cells; Niemann Pick type C disease; Valproic acids

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL; HISTONE DEACETYLASE INHIBITOR; MANGANESE SUPEROXIDE DISMUTASE; VALPROIC ACID;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRUCTURE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE REPRESSION; HOMEOSTASIS; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELLS, CULTURED; CHOLESTEROL; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HISTONE DEACETYLASES; MICE; NEURONS; NIEMANN-PICK DISEASES; PROTEINS; STEM CELLS; VALPROIC ACID;

MUS;

EID: 34447325642     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.116     Document Type: Article

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