메뉴 건너뛰기




Volumn 6, Issue 7, 2013, Pages e201303019-

The role of mitochondria in the development and progression of lung cancer

Author keywords

Apoptosis; Mitochondrial dynamics; Mitochondrial dysfunction; Non small cell lung cancer; Tumorigenesis

Indexed keywords


EID: 84902176690     PISSN: None     EISSN: 20010370     Source Type: Journal    
DOI: 10.5936/csbj.201303019     Document Type: Conference Paper
Times cited : (34)

References (147)
  • 1
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A Review of Programmed Cell Death
    • DOI 10.1080/01926230701320337, PII 779478428
    • Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35:495-516. (Pubitemid 46911891)
    • (2007) Toxicologic Pathology , vol.35 , Issue.4 , pp. 495-516
    • Elmore, S.1
  • 2
    • 79955374410 scopus 로고    scopus 로고
    • Organization WH, editor
    • (2013) Cancer Fact Sheet N.297. In: Organization WH, editor.
    • (2013) Cancer Fact Sheet N.297
  • 4
    • 77953175143 scopus 로고    scopus 로고
    • Institute NC, editor: U. S. National Institutes of Health
    • (2010) SEER Cancer Statistics Review, 1975-2010. In: Institute NC, editor: U. S. National Institutes of Health.
    • (2010) SEER Cancer Statistics Review, 1975-2010
  • 5
    • 84902151707 scopus 로고    scopus 로고
    • Institute NC, editor: U. S. National Institutes of Health
    • (2011) A Snapshot of Lung Cancer. In: Institute NC, editor: U. S. National Institutes of Health.
    • (2011) A Snapshot of Lung Cancer
  • 7
    • 84863123131 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation
    • Dasgupta S, Soudry E, Mukhopadhyay N, Shao C, Yee J, et al. (2012) Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation. J Cell Physiol 227:2451-2460.
    • (2012) J Cell Physiol , vol.227 , pp. 2451-2460
    • Dasgupta, S.1    Soudry, E.2    Mukhopadhyay, N.3    Shao, C.4    Yee, J.5
  • 8
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • Warburg O (1956) On respiratory impairment in cancer cells. Science 124:269-270.
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 9
    • 27844526600 scopus 로고    scopus 로고
    • Akt-dependent transformation: There is more to growth than just surviving
    • DOI 10.1038/sj.onc.1209097, PII 1209097
    • Plas DR, Thompson CB (2005) Akt-dependent transformation: there is more to growth than just surviving. Oncogene 24:7435-7442. (Pubitemid 41637983)
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7435-7442
    • Plas, D.R.1    Thompson, C.B.2
  • 12
    • 77953500851 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases and cancer
    • de Moura MB, dos Santos LS, Van Houten B (2010) Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen 51:391-405.
    • (2010) Environ Mol Mutagen , vol.51 , pp. 391-405
    • De Moura, M.B.1    Dos Santos, L.S.2    Van Houten, B.3
  • 16
    • 58149136865 scopus 로고    scopus 로고
    • Roles of p53, MYC and HIF-1 in regulating glycolysis - The seventh hallmark of cancer
    • Yeung SJ, Pan J, Lee MH (2008) Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer. Cell Mol Life Sci 65:3981-3999.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3981-3999
    • Yeung, S.J.1    Pan, J.2    Lee, M.H.3
  • 18
    • 0037634018 scopus 로고    scopus 로고
    • AMPK-β1 subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression
    • DOI 10.1093/carcin/bgg032
    • Li J, Jiang P, Robinson M, Lawrence TS, Sun Y (2003) AMPK-betal subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression. Carcinogenesis 24:827-834. (Pubitemid 36748898)
    • (2003) Carcinogenesis , vol.24 , Issue.5 , pp. 827-834
    • Li, J.1    Jiang, P.2    Robinson, M.3    Lawrence, T.S.4    Sun, Y.5
  • 19
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
    • Shackelford DB, Shaw RJ (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 9:563-575.
    • (2009) Nat Rev Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 20
    • 37349070024 scopus 로고    scopus 로고
    • An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death
    • DOI 10.1016/j.ccr.2007.11.031, PII S1535610807003704
    • Hallstrom TC, Mori S, Nevins JR (2008) An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell 13:11-22. (Pubitemid 350309738)
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 11-22
    • Hallstrom, T.C.1    Mori, S.2    Nevins, J.R.3
  • 21
    • 53149109725 scopus 로고    scopus 로고
    • C-Myc: Linking transformation and genomic instability
    • Prochownik EV (2008) c-Myc: linking transformation and genomic instability. Curr Mol Med 8:446-458.
    • (2008) Curr Mol Med , vol.8 , pp. 446-458
    • Prochownik, E.V.1
  • 22
    • 0032905924 scopus 로고    scopus 로고
    • C-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV (1999) c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 19:1-11. (Pubitemid 29018404)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.1 , pp. 1-11
    • Dang, C.V.1
  • 23
    • 43549098260 scopus 로고    scopus 로고
    • The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry
    • Morrish F, Neretti N, Sedivy JM, Hockenbery DM (2008) The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle 7:1054-1066.
    • (2008) Cell Cycle , vol.7 , pp. 1054-1066
    • Morrish, F.1    Neretti, N.2    Sedivy, J.M.3    Hockenbery, D.M.4
  • 25
    • 33846948971 scopus 로고    scopus 로고
    • The regulation of energy generating metabolic pathways by p53
    • Corcoran CA, Huang Y, Sheikh MS (2006) The regulation of energy generating metabolic pathways by p53. Cancer Biol Ther 5:1610-1613.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1610-1613
    • Corcoran, C.A.1    Huang, Y.2    Sheikh, M.S.3
  • 27
    • 56849118516 scopus 로고    scopus 로고
    • Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
    • Nogueira V, Park Y, Chen CC, Xu PZ, Chen ML, et al. (2008) Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14:458-470.
    • (2008) Cancer Cell , vol.14 , pp. 458-470
    • Nogueira, V.1    Park, Y.2    Chen, C.C.3    Xu, P.Z.4    Chen, M.L.5
  • 34
    • 43049102429 scopus 로고    scopus 로고
    • Alteration of APE1/ref-1 expression in non-small cell lung cancer: The implications of impaired extracellular superoxide dismutase and catalase antioxidant systems
    • DOI 10.1016/j.lungcan.2007.10.015, PII S0169500207006125
    • Yoo DG, Song YJ, Cho EJ, Lee SK, Park JB, et al. (2008) Alteration of APEl/ref-1 expression in non-small cell lung cancer: the implications of impaired extracellular superoxide dismutase and catalase antioxidant systems. Lung Cancer 60:277-284. (Pubitemid 351622081)
    • (2008) Lung Cancer , vol.60 , Issue.2 , pp. 277-284
    • Yoo, D.G.1    Song, Y.J.2    Cho, E.J.3    Lee, S.K.4    Park, J.B.5    Yu, J.H.6    Lim, S.P.7    Kim, J.M.8    Jeon, B.H.9
  • 35
  • 36
    • 0030925951 scopus 로고    scopus 로고
    • Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis
    • DOI 10.1002/elps.1150180504
    • Alonso A, Martin P, Albarran C, Aquilera B, Garcia O, et al. (1997) Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis. Electrophoresis 18:682-685. (Pubitemid 27226964)
    • (1997) Electrophoresis , vol.18 , Issue.5 , pp. 682-685
    • Alonso, A.1    Martin, P.2    Albarran, C.3    Aguilera, B.4    Garcia, O.5    Guzman, A.6    Oliva, H.7    Sancho, M.8
  • 38
    • 0039250954 scopus 로고    scopus 로고
    • Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
    • DOI 10.1126/science.287.5460.2017
    • Fliss MS, Usadel H, Caballero OL, Wu L, Buta MR, et al. (2000) Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287:2017-2019. (Pubitemid 30158678)
    • (2000) Science , vol.287 , Issue.5460 , pp. 2017-2019
    • Fliss, M.S.1    Usadel, H.2    Caballero, O.L.3    Wu, L.4    Buta, M.R.5    Eleff, S.M.6    Jen, J.7    Sidransky, D.8
  • 39
    • 0034109860 scopus 로고    scopus 로고
    • Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma
    • Habano W, Sugai T, Nakamura SI, Uesugi N, Yoshida T, et al. (2000) Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma. Gastroenterology 118:835-841. (Pubitemid 30243746)
    • (2000) Gastroenterology , vol.118 , Issue.5 , pp. 835-841
    • Habano, W.1    Sugai, T.2    Nakamura, S.3    Uesugi, N.4    Yoshida, T.5    Sasou, S.6
  • 40
    • 0032729633 scopus 로고    scopus 로고
    • Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
    • DOI 10.1002/(SICI)1097-0215(19991126)83:5<625: :AID-IJC10>3.0.CO;2- N
    • Habano W, Sugai T, Yoshida T, Nakamura S (1999) Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int J Cancer 83:625-629. (Pubitemid 29508041)
    • (1999) International Journal of Cancer , vol.83 , Issue.5 , pp. 625-629
    • Habano, W.1    Sugai, T.2    Yoshida, T.3    Nakamura, S.-I.4
  • 43
    • 84877584494 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in exhaled breath condensate of patients with lung cancer
    • Yang Ai SS, Hsu K, Herbert C, Cheng Z, Hunt J, et al. (2013) Mitochondrial DNA mutations in exhaled breath condensate of patients with lung cancer. Respir Med 107:911-918.
    • (2013) Respir Med , vol.107 , pp. 911-918
    • Yang Ai, S.S.1    Hsu, K.2    Herbert, C.3    Cheng, Z.4    Hunt, J.5
  • 44
    • 59449084794 scopus 로고    scopus 로고
    • Mitochondrial DNA content and lung cancer risk in Xuan Wei, China
    • Bonner MR, Shen M, Liu CS, Divita M, He X, et al. (2009) Mitochondrial DNA content and lung cancer risk in Xuan Wei, China. Lung Cancer 63:331-334.
    • (2009) Lung Cancer , vol.63 , pp. 331-334
    • Bonner, M.R.1    Shen, M.2    Liu, C.S.3    Divita, M.4    He, X.5
  • 45
  • 48
    • 66349123690 scopus 로고    scopus 로고
    • Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1
    • Thomas KJ, Sandebring A, Beilina A, van der Brug M, Cleland MM, et al. (2009) Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. PLoS One 4:e5701.
    • (2009) PLoS One , vol.4
    • Thomas, K.J.1    Sandebring, A.2    Beilina, A.3    Van Der Brug, M.4    Cleland, M.M.5
  • 49
    • 0034525413 scopus 로고    scopus 로고
    • VDAC regulation by the Bcl-2 family of proteins
    • DOI 10.1038/sj.cdd.4400780
    • Tsujimoto Y, Shimizu S (2000) VDAC regulation by the Bcl-2 family of proteins. Cell Death Differ 7:1174-1181. (Pubitemid 32042224)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.12 , pp. 1174-1181
    • Tsujimoto, Y.1    Shimizu, S.2
  • 51
    • 16444386967 scopus 로고    scopus 로고
    • Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis
    • DOI 10.1158/0008-5472.CAN-04-2012
    • Shidara Y, Yamagata K, Kanamori T, Nakano K, Kwong JQ, et al. (2005) Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res 65:1655-1663. (Pubitemid 40478589)
    • (2005) Cancer Research , vol.65 , Issue.5 , pp. 1655-1663
    • Shidara, Y.1    Yamagata, K.2    Kanamori, T.3    Nakano, K.4    Kwong, J.Q.5    Manfredi, G.6    Oda, H.7    Ohta, S.8
  • 53
    • 0035942505 scopus 로고    scopus 로고
    • Defective caspase-3 relocalization in non-small cell lung carcinoma
    • DOI 10.1038/sj.onc.1204402
    • Joseph B, Ekedahl J, Lewensohn R, Marchetti P, Formstecher P, et al. (2001) Defective caspase-3 relocalization in non-small cell lung carcinoma. Oncogene 20:2877-2888. (Pubitemid 33027755)
    • (2001) Oncogene , vol.20 , Issue.23 , pp. 2877-2888
    • Joseph, B.1    Ekedahl, J.2    Lewensohn, R.3    Marchetti, P.4    Formstecher, P.5    Zhivotovsky, B.6
  • 54
    • 0035523826 scopus 로고    scopus 로고
    • How melanoma cells evade trail-induced apoptosis
    • Hersey P, Zhang XD (2001) How melanoma cells evade trailinduced apoptosis. Nat Rev Cancer 1:142-150. (Pubitemid 33741889)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.2 , pp. 142-150
    • Hersey, P.1    Zhang, X.D.2
  • 55
    • 0032191676 scopus 로고    scopus 로고
    • Higher spontaneous apoptotic index in small cell compared with non-small cell lung carcinoma cell lines; lack of correlation with Bcl-2/Bax
    • DOI 10.1016/S0169-5002(98)00066-X, PII S016950029800066X
    • Sirzen F, Zhivotovsky B, Nilsson A, Bergh J, Lewensohn R (1998) Higher spontaneous apoptotic index in small cell compared with non-small cell lung carcinoma cell lines; lack of correlation with Bcl-2/Bax. Lung Cancer 22:1-13. (Pubitemid 28526438)
    • (1998) Lung Cancer , vol.22 , Issue.1 , pp. 1-13
    • Sirzen, F.1    Zhivotovsky, B.2    Nilsson, A.3    Bergh, J.4    Lewensohn, R.5
  • 57
    • 0032403126 scopus 로고    scopus 로고
    • IAP-family protein Survivin inhibits caspase activity and apoptosis induced by Fas (CD95), bax, caspases, and anticancer drugs
    • Tamm I, Wang Y, Sausville E, Scudiero DA, Vigna N, et al. (1998) IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 58:5315-5320. (Pubitemid 28551107)
    • (1998) Cancer Research , vol.58 , Issue.23 , pp. 5315-5320
    • Tamm, I.1    Wang, Y.2    Sausville, E.3    Scudiero, D.A.4    Vigna, N.5    Oltersdorf, T.6    Reed, J.C.7
  • 60
    • 0032080378 scopus 로고    scopus 로고
    • Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas
    • Lu CD, Altieri DC, Tanigawa N (1998) Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res 58:1808-1812. (Pubitemid 28217451)
    • (1998) Cancer Research , vol.58 , Issue.9 , pp. 1808-1812
    • Lu, C.-D.1    Altieri, D.C.2    Tanigawa, N.3
  • 61
    • 0342657718 scopus 로고    scopus 로고
    • A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
    • Olie RA, Simoes-Wust AP, Baumann B, Leech SH, Fabbro D, et al. (2000) A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res 60:2805-2809. (Pubitemid 30395796)
    • (2000) Cancer Research , vol.60 , Issue.11 , pp. 2805-2809
    • Olie, R.A.1    Simoes-Wust, A.P.2    Baumann, B.3    Leech, S.H.4    Fabbro, D.5    Stahel, R.A.6    Zangemeister-Wittke, U.7
  • 62
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • DOI 10.1038/35048073
    • Zamzami N, Kroemer G (2001) The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2:67-71. (Pubitemid 33676964)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.1 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 63
    • 77249119762 scopus 로고    scopus 로고
    • The landscape of somatic copy-number alteration across human cancers
    • Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, et al. (2010) The landscape of somatic copy-number alteration across human cancers. Nature 463:899-905.
    • (2010) Nature , vol.463 , pp. 899-905
    • Beroukhim, R.1    Mermel, C.H.2    Porter, D.3    Wei, G.4    Raychaudhuri, S.5
  • 64
    • 33846964621 scopus 로고    scopus 로고
    • Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
    • Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, et al. (2007) Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315:856-859.
    • (2007) Science , vol.315 , pp. 856-859
    • Willis, S.N.1    Fletcher, J.I.2    Kaufmann, T.3    Van Delft, M.F.4    Chen, L.5
  • 65
    • 78649700978 scopus 로고    scopus 로고
    • BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program
    • Ren D, Tu HC, Kim H, Wang GX, Bean GR, et al. (2010) BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program. Science 330:1390-1393.
    • (2010) Science , vol.330 , pp. 1390-1393
    • Ren, D.1    Tu, H.C.2    Kim, H.3    Wang, G.X.4    Bean, G.R.5
  • 67
    • 0033754569 scopus 로고    scopus 로고
    • Expression of p21 in non small cell lung cancer relationship with PCNA
    • Groeger AM, Caputi M, Esposito V, Baldi A, Rossiello R, et al. (2000) Expression of p21 in non small cell lung cancer relationship with PCNA Anticancer Res 20:3301-3305.
    • (2000) Anticancer Res , vol.20 , pp. 3301-3305
    • Groeger, A.M.1    Caputi, M.2    Esposito, V.3    Baldi, A.4    Rossiello, R.5
  • 68
    • 0033025610 scopus 로고    scopus 로고
    • Survival in small cell lung carcinoma is independent of bcl-2 expression
    • DOI 10.1016/S0046-8177(99)90099-0
    • Maitra A, Amirkhan RH, Saboorian MH, Frawley WH, Ashfaq R (1999) Survival in small cell lung carcinoma is independent of Bcl-2 expression. Hum Pathol 30:712-717. (Pubitemid 29266733)
    • (1999) Human Pathology , vol.30 , Issue.6 , pp. 712-717
    • Maitra, A.1    Amirkhan, R.H.2    Saboorian, M.H.3    Frawley, W.H.4    Ashfaq, R.5
  • 71
    • 0036187036 scopus 로고    scopus 로고
    • Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
    • DOI 10.1016/S1097-2765(02)00442-2
    • Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, et al. (2002) Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell 9:423-432. (Pubitemid 34195566)
    • (2002) Molecular Cell , vol.9 , Issue.2 , pp. 423-432
    • Acehan, D.1    Jiang, X.2    Morgan, D.G.3    Heuser, J.E.4    Wang, X.5    Akey, C.W.6
  • 72
    • 0034740463 scopus 로고    scopus 로고
    • Expression of the prothymosin-α gene as a prognostic factor in lung cancer
    • DOI 10.1007/s005950170040
    • Sasaki H, Nonaka M, Fujii Y, Yamakawa Y, Fukai I, et al. (2001) Expression of the prothymosin-a gene as a prognostic factor in lung cancer. Surg Today 31:936-938. (Pubitemid 33036173)
    • (2001) Surgery Today , vol.31 , Issue.10 , pp. 936-938
    • Sasaki, H.1    Nonaka, M.2    Fujii, Y.3    Yamakawa, Y.4    Fukai, I.5    Kiriyama, M.6    Sasaki, M.7
  • 73
    • 0031708908 scopus 로고    scopus 로고
    • Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy
    • DOI 10.1002/(SICI)1097-0215(19981023)79:5<468: :AID-IJC4>3.0.CO;2-Z
    • Vargas-Roig LM, Gago FE, Tello O, Aznar JC, Ciocca DR (1998) Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy. Int J Cancer 79:468-475. (Pubitemid 28445267)
    • (1998) International Journal of Cancer , vol.79 , Issue.5 , pp. 468-475
    • Vargas-Roig, L.M.1    Gago, F.E.2    Tello, O.3    Aznar, J.C.4    Ciocca, D.R.5
  • 77
    • 12344292783 scopus 로고    scopus 로고
    • Origins and selection of p53 mutations in lung carcinogenesis
    • DOI 10.1016/j.semcancer.2004.08.005, PII S1044579X04000732, Microenvironmental Regulation of Tumor Development
    • Rodin SN, Rodin AS (2005) Origins and selection of p53 mutations in lung carcinogenesis. Semin Cancer Biol 15:103-112. (Pubitemid 40126241)
    • (2005) Seminars in Cancer Biology , vol.15 , Issue.2 , pp. 103-112
    • Rodin, S.N.1    Rodin, A.S.2
  • 78
    • 0028363282 scopus 로고
    • Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens
    • Dowell SP, Wilson PO, Derias NW, Lane DP, Hall PA (1994) Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens. Cancer Res 54:2914-2918. (Pubitemid 24187772)
    • (1994) Cancer Research , vol.54 , Issue.11 , pp. 2914-2918
    • Dowell, S.P.1    Wilson, P.O.G.2    Derias, N.W.3    Lane, D.P.4    Hall, P.A.5
  • 81
    • 80052664208 scopus 로고    scopus 로고
    • Recent advances in p53 research and cancer treatment
    • Suzuki K, Matsubara H (2011) Recent advances in p53 research and cancer treatment. J Biomed Biotechnol 2011:978312.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 978312
    • Suzuki, K.1    Matsubara, H.2
  • 82
    • 56149109528 scopus 로고    scopus 로고
    • A small molecule that disrupts Mdm2-p53 binding activates p53, induces apoptosis and sensitizes lung cancer cells to chemotherapy
    • Sun SH, Zheng M, Ding K, Wang S, Sun Y (2008) A small molecule that disrupts Mdm2-p53 binding activates p53, induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Biol Ther 7:845-852.
    • (2008) Cancer Biol Ther , vol.7 , pp. 845-852
    • Sun, S.H.1    Zheng, M.2    Ding, K.3    Wang, S.4    Sun, Y.5
  • 83
    • 33745872296 scopus 로고    scopus 로고
    • Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins
    • DOI 10.1038/sj.cdd.4401937, PII 4401937
    • Zhai D, Jin C, Satterthwait AC, Reed JC (2006) Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins. Cell Death Differ 13:1419-1421. (Pubitemid 44057478)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1419-1421
    • Zhai, D.1    Jin, C.2    Satterthwait, A.C.3    Reed, J.C.4
  • 84
    • 22244432513 scopus 로고    scopus 로고
    • Killing cancer cells by flipping the Bcl-2/Bax switch
    • DOI 10.1016/j.ccr.2005.06.012, PII S1535610805001984
    • Cory S, Adams JM (2005) Killing cancer cells by flipping the Bcl-2/Bax switch. Cancer Cell 8:5-6. (Pubitemid 40991809)
    • (2005) Cancer Cell , vol.8 , Issue.1 , pp. 5-6
    • Cory, S.1    Adams, J.M.2
  • 87
    • 79952291173 scopus 로고    scopus 로고
    • Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors
    • Gandhi L, Camidge DR, Ribeiro de Oliveira M, Bonomi P, Gandara D, et al. (2011) Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors. J Clin Oncol 29:909-916.
    • (2011) J Clin Oncol , vol.29 , pp. 909-916
    • Gandhi, L.1    Camidge, D.R.2    Ribeiro De Oliveira, M.3    Bonomi, P.4    Gandara, D.5
  • 88
    • 3543048837 scopus 로고    scopus 로고
    • Targeted lung cancer therapies
    • Farmer G (2004) Targeted lung cancer therapies. Nat Rev Drug Discov 3:547-548. (Pubitemid 39022978)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.7 , pp. 547-548
    • Farmer, G.1
  • 90
    • 34447294826 scopus 로고    scopus 로고
    • TRAIL therapy in non-small cell lung cancer cells: Sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib
    • DOI 10.1158/1535-7163.MCT-07-0167
    • Voortman J, Resende TP, Abou El Hassan MA, Giaccone G, Kruyt FA (2007) TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib. Mol Cancer Ther 6:2103-2112. (Pubitemid 47052501)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.7 , pp. 2103-2112
    • Voortman, J.1    Resende, T.P.2    Abou El Hassan, M.A.3    Giaccone, G.4    Kruyt, F.A.E.5
  • 91
    • 33645822558 scopus 로고    scopus 로고
    • Tumour suppressor PTEN regulates cell cycle and protein kinase B/Akt pathway in breast cancer cells
    • Hlobilkova A, Knillova J, Svachova M, Skypalova P, Krystof V, et al. (2006) Tumour suppressor PTEN regulates cell cycle and protein kinase B/Akt pathway in breast cancer cells. Anticancer Res 26:1015-1022.
    • (2006) Anticancer Res , vol.26 , pp. 1015-1022
    • Hlobilkova, A.1    Knillova, J.2    Svachova, M.3    Skypalova, P.4    Krystof, V.5
  • 93
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: Dynamic Organelles in Disease, Aging, and Development
    • DOI 10.1016/j.cell.2006.06.010, PII S0092867406007689
    • Chan DC (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125:1241-1252. (Pubitemid 43929096)
    • (2006) Cell , vol.125 , Issue.7 , pp. 1241-1252
    • Chan, D.C.1
  • 94
    • 84875906572 scopus 로고    scopus 로고
    • Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure
    • Liesa M, Shirihai OS (2013) Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab 17:491-506.
    • (2013) Cell Metab , vol.17 , pp. 491-506
    • Liesa, M.1    Shirihai, O.S.2
  • 95
    • 80055078418 scopus 로고    scopus 로고
    • The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention
    • Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, et al. (2011) The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Curr Pharm Des 17:3374-3380.
    • (2011) Curr Pharm Des , vol.17 , pp. 3374-3380
    • Bonda, D.J.1    Smith, M.A.2    Perry, G.3    Lee, H.G.4    Wang, X.5
  • 96
    • 33749846225 scopus 로고    scopus 로고
    • Role of Bax and Bak in mitochondrial morphogenesis
    • DOI 10.1038/nature05111, PII NATURE05111
    • Karbowski M, Norris KL, Cleland MM, Jeong SY, Youle RJ (2006) Role of Bax and Bak in mitochondrial morphogenesis. Nature 443:658-662. (Pubitemid 44564703)
    • (2006) Nature , vol.443 , Issue.7112 , pp. 658-662
    • Karbowski, M.1    Norris, K.L.2    Cleland, M.M.3    Jeong, S.-Y.4    Youle, R.J.5
  • 97
    • 33745026786 scopus 로고    scopus 로고
    • GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission
    • DOI 10.1038/nature04718, PII NATURE04718
    • Roux A, Uyhazi K, Frost A, De Camilli P (2006) GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature 441:528-531. (Pubitemid 44050156)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 528-531
    • Roux, A.1    Uyhazi, K.2    Frost, A.3    De Camilli, P.4
  • 98
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • DOI 10.1083/jcb.200211046
    • Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, et al. (2003) Mitofusins Mfnl and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160:189-200. (Pubitemid 36254953)
    • (2003) Journal of Cell Biology , vol.160 , Issue.2 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 100
    • 34548313686 scopus 로고    scopus 로고
    • Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
    • DOI 10.1083/jcb.200704112
    • Griparic L, Kanazawa T, van der Bliek AM (2007) Regulation of the mitochondrial dynamin-like protein Opal by proteolytic cleavage. J Cell Biol 178:757-764. (Pubitemid 47347361)
    • (2007) Journal of Cell Biology , vol.178 , Issue.5 , pp. 757-764
    • Griparic, L.1    Kanazawa, T.2    Van Der Bliek, A.M.3
  • 101
    • 0037417334 scopus 로고    scopus 로고
    • Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
    • DOI 10.1083/jcb.200212059
    • Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC (2003) Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol 160:1115-1127. (Pubitemid 36443879)
    • (2003) Journal of Cell Biology , vol.160 , Issue.7 , pp. 1115-1127
    • Breckenridge, D.G.1    Stojanovic, M.2    Marcellus, R.C.3    Shore, G.C.4
  • 102
    • 34249019899 scopus 로고    scopus 로고
    • Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
    • DOI 10.1038/sj.cdd.4402107, PII 4402107
    • Estaquier J, Arnoult D (2007) Inhibiting Drpl-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis. Cell Death Differ 14:1086-1094. (Pubitemid 46785100)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.6 , pp. 1086-1094
    • Estaquier, J.1    Arnoult, D.2
  • 103
    • 84871309844 scopus 로고    scopus 로고
    • Inactivation of MARCH 5 prevents mitochondrial fragmentation and interferes with cell death in a neuronal cell model
    • Fang L, Hemion C, Goldblum D, Meyer P, Orgul S, et al. (2012) Inactivation of MARCH 5 prevents mitochondrial fragmentation and interferes with cell death in a neuronal cell model. PLoS One 7:e52637.
    • (2012) PLoS One , vol.7
    • Fang, L.1    Hemion, C.2    Goldblum, D.3    Meyer, P.4    Orgul, S.5
  • 104
    • 4644242944 scopus 로고    scopus 로고
    • Endophilin B1 is required for the maintenance of mitochondrial morphology
    • DOI 10.1083/jcb.200407046
    • Karbowski M, Jeong SY, Youle RJ (2004) Endophilin Bl is required for the maintenance of mitochondrial morphology. J Cell Biol 166:1027-1039. (Pubitemid 39304766)
    • (2004) Journal of Cell Biology , vol.166 , Issue.7 , pp. 1027-1039
    • Karbowski, M.1    Jeong, S.-Y.2    Youle, R.J.3
  • 105
    • 27144477744 scopus 로고    scopus 로고
    • Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1
    • DOI 10.1242/jcs.02537
    • Yu T, Fox RJ, Burwell LS, Yoon Y (2005) Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFisl. J Cell Sci 118:4141-4151. (Pubitemid 41488953)
    • (2005) Journal of Cell Science , vol.118 , Issue.18 , pp. 4141-4151
    • Yu, T.1    Fox, R.J.2    Burwell, L.S.3    Yoon, Y.4
  • 106
    • 27444446030 scopus 로고    scopus 로고
    • Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation
    • DOI 10.1074/jbc.M505970200
    • Arnoult D, Grodet A, Lee YJ, Estaquier J, Blackstone C (2005) Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation. J Biol Chem 280:35742-35750. (Pubitemid 41532767)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.42 , pp. 35742-35750
    • Arnoult, D.1    Grodet, A.2    Lee, Y.-J.3    Estaquier, J.4    Blackstone, C.5
  • 108
    • 34248182897 scopus 로고    scopus 로고
    • Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
    • DOI 10.1083/jcb.200610042
    • Wasiak S, Zunino R, McBride HM (2007) Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol 177:439-450. (Pubitemid 46718273)
    • (2007) Journal of Cell Biology , vol.177 , Issue.3 , pp. 439-450
    • Wasiak, S.1    Zunino, R.2    McBride, H.M.3
  • 110
    • 18444400187 scopus 로고    scopus 로고
    • Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis
    • DOI 10.1038/sj.emboj.7600592
    • Germain M, Mathai JP, McBride HM, Shore GC (2005) Endoplasmic reticulum BIK initiates DRPl-regulated remodelling of mitochondrial cristae during apoptosis. Embo J 24:1546-1556. (Pubitemid 40646445)
    • (2005) EMBO Journal , vol.24 , Issue.8 , pp. 1546-1556
    • Germain, M.1    Mathai, J.P.2    McBride, H.M.3    Shore, G.C.4
  • 111
    • 6344274848 scopus 로고    scopus 로고
    • Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, Opa1 in apoptosis
    • DOI 10.1091/mbc.E04-04-0294
    • Lee YJ, Jeong SY, Karbowski M, Smith CL, Youle RJ (2004) Roles of the mammalian mitochondrial fission and fusion mediators Fisl, Drpl, and Opal in apoptosis. Mol Biol Cell 15:5001-5011. (Pubitemid 39392214)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.11 , pp. 5001-5011
    • Lee, Y.-J.1    Jeong, S.-Y.2    Karbowski, M.3    Smith, C.L.4    Youle, R.J.5
  • 112
    • 84866641257 scopus 로고    scopus 로고
    • Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model
    • Thomas KJ, Jacobson MR (2012) Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model. PLoS One 7:e45319.
    • (2012) PLoS One , vol.7
    • Thomas, K.J.1    Jacobson, M.R.2
  • 113
    • 52449134835 scopus 로고    scopus 로고
    • Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA
    • Parone PA, Da Cruz S, Tondera D, Mattenberger Y, James DI, et al. (2008) Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA. PLoS One 3:e3257.
    • (2008) PLoS One , vol.3
    • Parone, P.A.1    Da Cruz, S.2    Tondera, D.3    Mattenberger, Y.4    James, D.I.5
  • 114
    • 84874694989 scopus 로고    scopus 로고
    • Mitochondrial hyperfusion induced by loss of the fission protein Drpl causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress
    • Qian W, Choi S, Gibson GA, Watkins SC, Bakkenist CJ, et al. (2012) Mitochondrial hyperfusion induced by loss of the fission protein Drpl causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci 125:5745-5757.
    • (2012) J Cell Sci , vol.125 , pp. 5745-5757
    • Qian, W.1    Choi, S.2    Gibson, G.A.3    Watkins, S.C.4    Bakkenist, C.J.5
  • 115
    • 45349094984 scopus 로고    scopus 로고
    • Mitochondrial dynamics and apoptosis
    • DOI 10.1101/gad.1658508
    • Suen DF, Norris KL, Youle RJ (2008) Mitochondrial dynamics and apoptosis. Genes Dev 22:1577-1590. (Pubitemid 351846838)
    • (2008) Genes and Development , vol.22 , Issue.12 , pp. 1577-1590
    • Suen, D.-F.1    Norris, K.L.2    Youle, R.J.3
  • 116
    • 79954569219 scopus 로고    scopus 로고
    • Regulation of mitochondrial morphology by APC/CCdhlmediated control of Drpl stability
    • Horn SR, Thomenius MJ, Johnson ES, Freel CD, Wu JQ, et al. (2011) Regulation of mitochondrial morphology by APC/CCdhlmediated control of Drpl stability. Mol Biol Cell 22:1207-1216.
    • (2011) Mol Biol Cell , vol.22 , pp. 1207-1216
    • Horn, S.R.1    Thomenius, M.J.2    Johnson, E.S.3    Freel, C.D.4    Wu, J.Q.5
  • 117
    • 77955431941 scopus 로고    scopus 로고
    • S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease
    • Bossy B, Petrilli A, Klinglmayr E, Chen J, Lutz-Meindl U, et al. (2010) S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis 20 Suppl2:S513-526.
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 2
    • Bossy, B.1    Petrilli, A.2    Klinglmayr, E.3    Chen, J.4    Lutz-Meindl, U.5
  • 118
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • DOI 10.1074/jbc.M607279200
    • Taguchi N, Ishihara N, Jofuku A, Oka T, Mihara K (2007) Mitotic phosphorylation of dynamin-related GTPase Drpl participates in mitochondrial fission. J Biol Chem 282:11521-11529. (Pubitemid 47100787)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.15 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 119
    • 34547611925 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
    • DOI 10.1074/jbc.C700083200
    • Chang CR, Blackstone C (2007) Cyclic AMP-dependent protein kinase phosphorylation of Drpl regulates its GTPase activity and mitochondrial morphology. J Biol Chem 282:21583-21587. (Pubitemid 47195725)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.30 , pp. 21583-21587
    • Chang, C.-R.1    Blackstone, C.2
  • 120
    • 0033870724 scopus 로고    scopus 로고
    • Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication
    • Soria JC, Jang SJ, Khuri FR, Hassan K, Liu D, et al. (2000) Overexpression of cyclin Bl in early-stage non-small cell lung cancer and its clinical implication. Cancer Res 60:4000-4004. (Pubitemid 30636572)
    • (2000) Cancer Research , vol.60 , Issue.15 , pp. 4000-4004
    • Soria, J.-C.1    Se Jin Jang2    Khuri, F.R.3    Hassan, K.4    Liu, D.5    Waun Ki Hong6    Mao, L.7
  • 121
    • 79960297569 scopus 로고    scopus 로고
    • Cdkl/cyclin Bl controls Fas-mediated apoptosis by regulating caspase-8 activity
    • Matthess Y, Raab M, Sanhaji M, Lavrik IN, Strebhardt K (2010) Cdkl/cyclin Bl controls Fas-mediated apoptosis by regulating caspase-8 activity. Mol Cell Biol 30:5726-5740.
    • (2010) Mol Cell Biol , vol.30 , pp. 5726-5740
    • Matthess, Y.1    Raab, M.2    Sanhaji, M.3    Lavrik, I.N.4    Strebhardt, K.5
  • 122
    • 77953149881 scopus 로고    scopus 로고
    • Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling
    • Feldmann G, Mishra A, Hong SM, Bisht S, Strock CJ, et al. (2010) Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling. Cancer Res 70:4460-4469.
    • (2010) Cancer Res , vol.70 , pp. 4460-4469
    • Feldmann, G.1    Mishra, A.2    Hong, S.M.3    Bisht, S.4    Strock, C.J.5
  • 124
    • 56949087771 scopus 로고    scopus 로고
    • Viral and cellular MARCH ubiquitin ligases and cancer
    • Wang X, Herr RA, Hansen T (2008) Viral and cellular MARCH ubiquitin ligases and cancer. Semin Cancer Biol 18:441-450.
    • (2008) Semin Cancer Biol , vol.18 , pp. 441-450
    • Wang, X.1    Herr, R.A.2    Hansen, T.3
  • 125
    • 34347398050 scopus 로고    scopus 로고
    • The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
    • DOI 10.1083/jcb.200611064
    • Karbowski M, Neutzner A, Youle RJ (2007) The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drpl dependent mitochondrial division. J Cell Biol 178:71-84. (Pubitemid 47026403)
    • (2007) Journal of Cell Biology , vol.178 , Issue.1 , pp. 71-84
    • Karbowski, M.1    Neutzner, A.2    Youle, R.J.3
  • 126
    • 0035827622 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax
    • Cuddeback SM, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, et al. (2001) Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem 276:20559-20565.
    • (2001) J Biol Chem , vol.276 , pp. 20559-20565
    • Cuddeback, S.M.1    Yamaguchi, H.2    Komatsu, K.3    Miyashita, T.4    Yamada, M.5
  • 127
    • 0035889088 scopus 로고    scopus 로고
    • Generation of high curvature membranes mediated by direct endophilin bilayer interactions
    • DOI 10.1083/jcb.200107075
    • Farsad K, Ringstad N, Takei K, Floyd SR, Rose K, et al. (2001) Generation of high curvature membranes mediated by direct endophilin bilayer interactions. J Cell Biol 155:193-200. (Pubitemid 34289294)
    • (2001) Journal of Cell Biology , vol.155 , Issue.2 , pp. 193-200
    • Farsad, K.1    Ringstad, N.2    Takei, K.3    Floyd, S.R.4    Rose, K.5    De Camilli, P.6
  • 128
    • 0035862577 scopus 로고    scopus 로고
    • SH3GLB, a new endophilin-related protein family featuring an SH3 domain
    • DOI 10.1006/geno.2000.6378
    • Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, et al. (2001) SH3GLB, a new endophilin-related protein family featuring an SH3 domain. Genomics 71:222-234. (Pubitemid 32165089)
    • (2001) Genomics , vol.71 , Issue.2 , pp. 222-234
    • Pierrat, B.1    Simonen, M.2    Cueto, M.3    Mestan, J.4    Ferrigno, P.5    Heim, J.6
  • 131
    • 10644296253 scopus 로고    scopus 로고
    • Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
    • DOI 10.1074/jbc.M408910200
    • Sugioka R, Shimizu S, Tsujimoto Y (2004) Fzol, a protein involved in mitochondrial fusion, inhibits apoptosis. J Biol Chem 279:52726-52734. (Pubitemid 39656648)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.50 , pp. 52726-52734
    • Sugioka, R.1    Shimizu, S.2    Tsujimoto, Y.3
  • 132
    • 67650868959 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammalian health and disease
    • Liesa M, Palacin M, Zorzano A (2009) Mitochondrial dynamics in mammalian health and disease. Physiol Rev 89:799-845.
    • (2009) Physiol Rev , vol.89 , pp. 799-845
    • Liesa, M.1    Palacin, M.2    Zorzano, A.3
  • 133
    • 0035893566 scopus 로고    scopus 로고
    • Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display
    • Chung JG, Yeh KT, Wu SL, Hsu NY, Chen GW, et al. (2001) Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display. Cancer Res 61:8873-8879.
    • (2001) Cancer Res , vol.61 , pp. 8873-8879
    • Chung, J.G.1    Yeh, K.T.2    Wu, S.L.3    Hsu, N.Y.4    Chen, G.W.5
  • 136
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • DOI 10.1074/jbc.C200677200
    • Olichon A, Baricault L, Gas N, Guillou E, Valette A, et al. (2003) Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 278:7743-7746. (Pubitemid 36800505)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6    Lenaers, G.7
  • 137
    • 83055173020 scopus 로고    scopus 로고
    • Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells
    • Fang HY, Chen CY, Chiou SH, Wang YT, Lin TY, et al. (2012) Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells. Hum Pathol 43:105-114.
    • (2012) Hum Pathol , vol.43 , pp. 105-114
    • Fang, H.Y.1    Chen, C.Y.2    Chiou, S.H.3    Wang, Y.T.4    Lin, T.Y.5
  • 138
    • 21644455319 scopus 로고    scopus 로고
    • Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization
    • DOI 10.1074/jbc.M501599200
    • Neuspiel M, Zunino R, Gangaraju S, Rippstein P, McBride H (2005) Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization. J Biol Chem 280:25060-25070. (Pubitemid 40934597)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.26 , pp. 25060-25070
    • Neuspiel, M.1    Zunino, R.2    Gangaraju, S.3    Rippstein, P.4    McBride, H.5
  • 139
    • 33745699393 scopus 로고    scopus 로고
    • OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
    • Frezza C, Cipolat S, Martins de Brito O, Micaroni M, Beznoussenko GV, et al. (2006) OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell 126:177-189.
    • (2006) Cell , vol.126 , pp. 177-189
    • Frezza, C.1    Cipolat, S.2    Martins De Brito, O.3    Micaroni, M.4    Beznoussenko, G.V.5
  • 140
    • 33745950626 scopus 로고    scopus 로고
    • Mitochondrial outer membrane permeabilization during apoptosis: The innocent bystander scenario
    • DOI 10.1038/sj.cdd.4401963, PII 4401963
    • Chipuk JE, Bouchier-Hayes L, Green DR (2006) Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ 13:1396-1402. (Pubitemid 44057475)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1396-1402
    • Chipuk, J.E.1    Bouchier-Hayes, L.2    Green, D.R.3
  • 143
    • 28444476999 scopus 로고    scopus 로고
    • Membrane curvature and mechanisms of dynamic cell membrane remodelling
    • DOI 10.1038/nature04396
    • McMahon HT, Gallop JL (2005) Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 438:590-596. (Pubitemid 41740562)
    • (2005) Nature , vol.438 , Issue.7068 , pp. 590-596
    • McMahon, H.T.1    Gallop, J.L.2
  • 145
    • 0019888247 scopus 로고
    • Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes
    • Bernardi P, Azzone GF (1981) Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes. J Biol Chem 256:7187-7192.
    • (1981) J Biol Chem , vol.256 , pp. 7187-7192
    • Bernardi, P.1    Azzone, G.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.