Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 21, 2004, Pages 7988-7993

  Arnoult, Damien ^a   Bartle, Laura M ^c   Skaletskaya, Anna ^c   Poncet, Delphine ^b   Zamzami, Naoufal ^b   Park, Peter U ^c   Sharpe, Juanita ^a   Youle, Richard J ^a   Goldmacher, Victor S ^c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c IMMUNOGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS CELL DEATH SUPPRESSOR VMIA PROTEIN; MUTANT PROTEIN; PROTEIN; PROTEIN BAK; PROTEIN BAX; UNCLASSIFIED DRUG; VMIA BAX COMPLEX;

APOPTOSIS; ARTICLE; CELL DEATH; HELA CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MITOCHONDRION TARGETING DOMAIN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE PERMEABILITY; CYTOMEGALOVIRUS; FIBROBLASTS; HELA CELLS; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; VIRAL PROTEINS;

CYTOMEGALOVIRUS;

EID: 2542629734     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0401897101     Document Type: Article

References (48)

1. Goldmacher, V. S., Bartle, L. M., Skaletskaya, A., Dionne, C. A., Kedersha, N. L., Vater, C. A., Han, J. W., Lutz, R. J., Watanabe, S., Cahir McFarland, E. D., et al. (1999) Proc. Natl. Acad. Sci. USA 96, 12536-12541.
2. McCormick, A. L., Skaletskaya, A., Barry, P. A., Mocarski, E. S. & Goldmacher, V. S. (2003) Virology 316, 221-233.
3. Goldmacher, V. S. (2002) Biochimie 84, 177-185.
4. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P. & Wang, X. (1997) Science 275, 1129-1132.
5. Kluck, R. M., Bossy-Wetzel, E., Green, D. R. & Newmeyer, D. D. (1997) Science 275, 1132-1136.
6. Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S. & Korsmeyer, S. J. (2002) Cancer Cell 2, 183-192.
7. Chittenden, T. (2002) Cancer Cell 2, 165-166.
8. Cheng, E. H., Wei, M. C., Weiler, S., Flavell, R. A., Mak, T. W., Lindsten, T. & Korsmeyer, S. J. (2001) Mol. Cell 8, 705-711.
9. Hsu, Y. T. & Youle, R. J. (1997) J. Biol. Chem. 272, 13829-13834.
10. Mikhailov, V., Mikhailova, M., Pulkrabek, D. J., Dong, Z., Venkatachalam, M. A. & Saikumar, P. (2001) J. Biol. Chem. 276, 18361-18374.
11. Simonian, P. L., Grillot, D. A., Merino, R. & Nunez, G. (1996) J. Biol. Chem. 271, 22764-22772.
12. Simonian, P. L., Grillot, D. A. & Nunez, G. (1997) Oncogene 15, 1871-1875.
13. Cheng, E. H., Levine, B., Boise, L. H., Thompson, C. B. & Hardwick, J. M. (1996) Nature 379, 554-556.
14. Zha, H. & Reed, J. C. (1997) J. Biol. Chem. 272, 31482-31488.
15. Wolter, K. G., Hsu, Y. T., Smith, C. L., Nechushtan, A., Xi, X. G. & Youle, R. J. (1997) J. Cell Biol. 139, 1281-1292.
16. Hayajneh, W. A., Colberg-Poley, A. M., Skaletskaya, A., Bartle, L. M., Lesperance, M. M., Contopoulos-Ioannidis, D. G., Kedersha, N. L. & Goldmacher, V. S. (2001) Virology 279, 233-240.
17. Skaletskaya, A., Bartle, L. M., Chittenden, T., McCormick, A. L., Mocarski, E. S. & Goldmacher, V. S. (2001) Proc. Natl. Acad. Sci. USA 98, 7829-7834.
18. Zhang, L., Yu, J., Park, B. H., Kinzler, K. W. & Vogelstein, B. (2000) Science 290, 989-992.
19. Antonsson, B., Montessuit, S., Lauper, S., Eskes, R. & Martinou, J. C. (2000) Biochem. J. 345, 271-278.
20. Suzuki, M., Youle, R. J. & Tjandra, N. (2000) Cell 103, 645-654.
21. Giron-Calle, J., Zwizinski, C. W. & Schmid, H. H. (1994) Arch. Biochem. Biophys. 315, 1-7.
22. Arnoult, D., Parone, P., Martinou, J. C., Antonsson, B., Estaquier, J. & Ameisen, J. C. (2002) J. Cell Biol. 159, 923-929.
23. Arnoult, D., Gaume, B., Karbowski, M., Sharpe, J. C., Cecconi, F. & Youle, R. J. (2003) EMBO J. 22, 4385-4399.
24. Chittenden, T., Harrington, E. A., O'Connor, R., Flemington, C., Lutz, R. J., Evan, G. I. & Guild, B. C. (1995) Nature 374, 733-736.
25. Farrow, S. N., White, J. H., Martinou, I., Raven, T., Pun, K. T., Grinham, C. J., Martinou, J. C. & Brown, R. (1995) Nature 374, 731-733.
26. Wei, M. C., Zong, W. X., Cheng, E. H., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B. & Korsmeyer, S. J. (2001) Science 292, 727-730.
27. Zamzami, N., Marchetti, P., Castedo, M., Decaudin, D., Macho, A., Hirsch, T., Susin, S. A., Petit, P. X., Mignotte, B. & Kroemer, G. (1995) J. Exp. Med. 182, 367-377.
28. Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B. & Martinou, J. C. (1999) J. Cell Biol. 144, 891-901.
29. Wei, M. C., Lindsten, T., Mootha, V. K., Weiler, S., Gross, A., Ashiya, M., Thompson, C. B. & Korsmeyer, S. J. (2000) Genes Dev. 14, 2060-2071.
30. Antonsson, B., Montessuit, S., Sanchez, B. & Martinou, J. C. (2001) J. Biol. Chem. 276, 11615-11623.
31. LeBlanc, H., Lawrence, D., Varfolomeev, E., Totpal, K., Morlan, J., Schow, P., Fong, S., Schwall, R., Sinicropi, D. & Ashkenazi, A. (2002) Nat. Med. 8, 274-281.
32. Gillissen, B., Essmann, F., Graupner, V., Starck, L., Radetzki, S., Dorken, B., Schulze-Osthoff, K. & Daniel, P. T. (2003) EMBO J. 22, 3580-3590.
33. Yamaguchi, H., Bhalla, K. & Wang, H. G. (2003) Cancer Res. 63, 1483-1489.
34. Theodorakis, P., Lomonosova, E. & Chinnadurai, G. (2002) Cancer Res. 62, 3373-3376.
35. He, Q., Montalbano, J., Corcoran, C., Jin, W., Huang, Y. & Sheikh, M. S. (2003) Oncogene 22, 2674-2679.
36. Mahyar-Roemer, M., Kohler, H. & Roemer, K. (2002) BMC Cancer 2, 27-35.
37. Eskes, R., Desagher, S., Antonsson, B. & Martinou, J. C. (2000) Mol. Cell. Biol. 20, 929-935.
38. Mavinakere, M. S. & Colberg-Poley, A. M. (2004) J. Gen. Virol. 85, 323-329.
39. Vieira, H. L., Boya, P., Cohen, I., El Hamel, C., Haouzi, D., Druillenec, S., Belzacq, A. S., Brenner, C., Roques, B. & Kroemer, G. (2002) Oncogene 21, 1963-1977.
40. Mikhailov, V., Mikhailova, M., Degenhardt, K., Venkatachalam, M. A., White, E. & Saikumar, P. (2003) J. Biol. Chem. 278, 5367-5376.
41. Juin, P., Hunt, A., Littlewood, T., Griffiths, B., Swigart, L. B., Korsmeyer, S. & Evan, G. (2002) Mol. Cell. Biol. 22, 6158-6169.
42. Cartron, P. F., Juin, P., Oliver, L., Martin, S., Meflah, K. & Vallette, F. M. (2003) Mol. Cell. Biol. 23, 4701-4712.
43. Cuconati, A., Degenhardt, K., Sundararajan, R., Anschel, A. & White, E. (2002) J. Virol. 76, 4547-4558.
44. Degenhardt, K., Sundararajan, R., Lindsten, T., Thompson, C. & White, E. (2002) J. Biol. Chem. 277, 14127-14134.
45. Scaffidi, C., Fulda, S., Srinivasan, A., Friesen, C., Li, F., Tomaselli, K. J., Debatin, K. M., Krammer, P. H. & Peter, M. E. (1998) EMBO J 17, 1675-1687.
46. Cuconati, A. & White, E. (2002) Genes Dev. 16, 2465-2478.
47. Sundararajan, R., Cuconati, A., Nelson, D. & White, E. (2001) J. Biol. Chem. 276, 45120-45127.
48. Guo, B., Zhai, D., Cabezas, E., Welsh, K., Nouraini, S., Satterthwait, A. C. & Reed, J. C. (2003) Nature 423, 456-461.