-
1
-
-
26444489119
-
Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis
-
Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Maurer U and Green DR (2005) Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis. Science 310: 66-67.
-
(2005)
Science
, vol.310
, pp. 66-67
-
-
Spierings, D.1
McStay, G.2
Saleh, M.3
Bender, C.4
Chipuk, J.5
Maurer, U.6
Green, D.R.7
-
2
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN and Korsmeyer SJ (2004) Cell death: Critical control points. Cell 116: 205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
3
-
-
0034520872
-
The 'harmless' release of cytochrome c
-
Von Ahsen O, Waterhouse NJ, Kuwana T, Newmeyer DD and Green DR (2000) The 'harmless' release of cytochrome c. Cell Death Differ. 7: 1192-1199.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1192-1199
-
-
Von Ahsen, O.1
Waterhouse, N.J.2
Kuwana, T.3
Newmeyer, D.D.4
Green, D.R.5
-
4
-
-
14644412456
-
Do inducers of apoptosis trigger caspase-independent cell death?
-
Chipuk JE and Green DR (2005) Do inducers of apoptosis trigger caspase-independent cell death? Nat. Rev. Mol. Cell. Biol. 6: 268-275.
-
(2005)
Nat. Rev. Mol. Cell. Biol.
, vol.6
, pp. 268-275
-
-
Chipuk, J.E.1
Green, D.R.2
-
5
-
-
0038146907
-
Mitochondrial functions during cell death, a complex (I-V) dilemma
-
Ricci JE, Waterhouse N and Green DR (2003) Mitochondrial functions during cell death, a complex (I-V) dilemma. Cell Death Differ. 10: 488-492.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 488-492
-
-
Ricci, J.E.1
Waterhouse, N.2
Green, D.R.3
-
6
-
-
0345276414
-
Bcl-2-family proteins and the role of mitochondria in apoptosis
-
Kuwana T and Newmeyer DD (2003) Bcl-2-family proteins and the role of mitochondria in apoptosis. Curr. Opin. Cell. Biol. 15: 691-699.
-
(2003)
Curr. Opin. Cell. Biol.
, vol.15
, pp. 691-699
-
-
Kuwana, T.1
Newmeyer, D.D.2
-
7
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S and Korsmeyer SJ (2002) Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell. 2: 183-192.
-
(2002)
Cancer Cell.
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
8
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R, Green DR and Newmeyer DD (2002) Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 111: 331-342.
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
Green, D.R.7
Newmeyer, D.D.8
-
9
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ (2001) Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
10
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T and Thompson CB (2005) Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120: 237-248.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
11
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR and Newmeyer DD (2005) BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol. Cell 17: 525-535.
-
(2005)
Mol. Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
Newmeyer, D.D.7
-
12
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL Adams JM and Huang DC (2005) Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell 17: 393-403.
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
13
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P and Moll UM (2003) p53 has a direct apoptogenic role at the mitochondria. Mol. Cell 11: 577-590.
-
(2003)
Mol. Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
14
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M and Green DR (2004) Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
15
-
-
33646826684
-
WTp53 but not tumor-derived mutants bind to BCL2 via the DNA binding domain and induce mitochondrial permeabilization
-
Tomita Y, Marchenko N, Erster S, Nemajerova A, Dehner A, Klein C, Pan H, Kessler H, Pancoska P and Moll UM (2006) WTp53 but not tumor-derived mutants bind to BCL2 via the DNA binding domain and induce mitochondrial permeabilization. J. Biol. Chem. 281: 8600-8606.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 8600-8606
-
-
Tomita, Y.1
Marchenko, N.2
Erster, S.3
Nemajerova, A.4
Dehner, A.5
Klein, C.6
Pan, H.7
Kessler, H.8
Pancoska, P.9
Moll, U.M.10
-
16
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C and Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
17
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ and Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
18
-
-
33745739717
-
Caspase-2-induced apoptosis requires bid cleavage: A physiological role for bid in heat shock-induced death
-
Bonzon C, Bouchier-Hayes L, Pagliari W, Green DR and Newmeyer DD (2006) Caspase-2-induced apoptosis requires bid cleavage: A physiological role for bid in heat shock-induced death. Mol. Biol. Cell. 17: 2150-2157.
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 2150-2157
-
-
Bonzon, C.1
Bouchier-Hayes, L.2
Pagliari, W.3
Green, D.R.4
Newmeyer, D.D.5
-
19
-
-
0034694083
-
Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax
-
Heibein JA, Goping IS, Barry M, Pinkoski MJ, Shore GC, Green DR and Bleackley RC (2000) Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax J. Exp. Med. 192: 1391-1402.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1391-1402
-
-
Heibein, J.A.1
Goping, I.S.2
Barry, M.3
Pinkoski, M.J.4
Shore, G.C.5
Green, D.R.6
Bleackley, R.C.7
-
20
-
-
0034107096
-
Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid
-
Barry M, Heibein JA, Pinkoski MJ, Lee SF, Moyer RW, Green DR and Bleackley RC (2000) Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid. Mol. Cell. Biol. 20: 3781-3794.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3781-3794
-
-
Barry, M.1
Heibein, J.A.2
Pinkoski, M.J.3
Lee, S.F.4
Moyer, R.W.5
Green, D.R.6
Bleackley, R.C.7
-
21
-
-
30344459150
-
In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis
-
Tu S, McStay GP, Boucher LM, Mak T, Beere HM and Green DR (2006) In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis. Nat. Cell Biol. 8: 72-77.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 72-77
-
-
Tu, S.1
McStay, G.P.2
Boucher, L.M.3
Mak, T.4
Beere, H.M.5
Green, D.R.6
-
22
-
-
0033104996
-
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
Puthalakath H, Huang DC, O'Reilly LA, King SM and Strasser A (1999) The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex Mol. Cell 3: 287-296.
-
(1999)
Mol. Cell
, vol.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.2
O'Reilly, L.A.3
King, S.M.4
Strasser, A.5
-
23
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T and Tanaka N (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
24
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K and Vousden KH (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7: 683-694.
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
25
-
-
0035823238
-
Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC and Strasser A (2001) Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 293: 1829-1832.
-
(2001)
Science
, vol.293
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
Huang, D.C.7
Strasser, A.8
-
27
-
-
27644597606
-
Mitochondrial permeability transition in apoptosis and necrosis
-
Zamzami N, Larochette N and Kroemer G (2005) Mitochondrial permeability transition in apoptosis and necrosis. Cell Death Differ. 12 (Suppl 2): 1478-1480.
-
(2005)
Cell Death Differ.
, vol.12
, Issue.SUPPL. 2
, pp. 1478-1480
-
-
Zamzami, N.1
Larochette, N.2
Kroemer, G.3
-
29
-
-
0033781027
-
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
-
Goldstein JC, Waterhouse NJ, Juin P, Evan GI and Green DR (2000) The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant Nat. Cell Biol. 2: 156-162.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 156-162
-
-
Goldstein, J.C.1
Waterhouse, N.J.2
Juin, P.3
Evan, G.I.4
Green, D.R.5
-
30
-
-
18644362771
-
Cytochrome c is released in a single step during apoptosis
-
Goldstein JC, Munoz-Pinedo C, Ricci JE, Adams SR, Kelekar A, Schuler M, Tsien RY and Green DR (2005) Cytochrome c is released in a single step during apoptosis. Cell Death Differ. 12: 453-462.
-
(2005)
Cell Death Differ.
, vol.12
, pp. 453-462
-
-
Goldstein, J.C.1
Munoz-Pinedo, C.2
Ricci, J.E.3
Adams, S.R.4
Kelekar, A.5
Schuler, M.6
Tsien, R.Y.7
Green, D.R.8
-
31
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA, Dorn GW, Robbins J and Molkentin JD (2005) Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434: 658-662.
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
Robbins, J.11
Molkentin, J.D.12
-
32
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T and Tsujimoto Y (2005) Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434: 652-658.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
33
-
-
0842307483
-
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
-
Kokoszka JE, Waymire KG, Levy SE, Sligh JE, Cai J, Jones DP, MacGregor GR and Wallace DC (2004) The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427: 461-465.
-
(2004)
Nature
, vol.427
, pp. 461-465
-
-
Kokoszka, J.E.1
Waymire, K.G.2
Levy, S.E.3
Sligh, J.E.4
Cai, J.5
Jones, D.P.6
MacGregor, G.R.7
Wallace, D.C.8
-
34
-
-
0037421221
-
Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis
-
Ricci JE, Gottlieb RA and Green DR (2003) Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J. Cell Biol. 160: 65-75.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 65-75
-
-
Ricci, J.E.1
Gottlieb, R.A.2
Green, D.R.3
-
35
-
-
2942581328
-
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
-
Ricci JE, Munoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH and Green DR (2004) Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117: 773-786.
-
(2004)
Cell
, vol.117
, pp. 773-786
-
-
Ricci, J.E.1
Munoz-Pinedo, C.2
Fitzgerald, P.3
Bailly-Maitre, B.4
Perkins, G.A.5
Yadava, N.6
Scheffler, I.E.7
Ellisman, M.H.8
Green, D.R.9
-
36
-
-
0035897408
-
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
-
Waterhouse NJ, Goldstein JC, von Ahsen O, Schuler M, Newmeyer DD and Green DR (2001) Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J. Cell Biol. 153: 319-328.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 319-328
-
-
Waterhouse, N.J.1
Goldstein, J.C.2
von Ahsen, O.3
Schuler, M.4
Newmeyer, D.D.5
Green, D.R.6
-
37
-
-
0345832111
-
Cardiolipin is not required for Bax-mediated cytochrome c release from yeast mitochondria
-
Iverson SL, Enoksson M, Gogvadze V, Ott M and Orrenius S (2004) Cardiolipin is not required for Bax-mediated cytochrome c release from yeast mitochondria. J. Biol. Chem. 279: 1100-1107.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1100-1107
-
-
Iverson, S.L.1
Enoksson, M.2
Gogvadze, V.3
Ott, M.4
Orrenius, S.5
-
38
-
-
18744374204
-
The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
-
Lutter M, Perkins GA and Wang X (2001) The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites. BMC Cell Biol. 2: 22.
-
(2001)
BMC Cell Biol.
, vol.2
, pp. 22
-
-
Lutter, M.1
Perkins, G.A.2
Wang, X.3
-
39
-
-
0034306169
-
Cardiolipin provides specificity for targeting of tBid to mitochondria
-
Lutter M, Fang M, Luo X, Nishijima M, Xie X and Wang X (2000) Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat. Cell Biol. 2: 754-761.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 754-761
-
-
Lutter, M.1
Fang, M.2
Luo, X.3
Nishijima, M.4
Xie, X.5
Wang, X.6
-
40
-
-
0034681110
-
Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity
-
Shimizu S and Tsujimoto Y (2000) Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity. Proc. Natl. Acad. Sci. USA 97: 577-582.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 577-582
-
-
Shimizu, S.1
Tsujimoto, Y.2
-
41
-
-
0034676090
-
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: Role of mitochondria and caspases
-
Ferri KF, Jacotot E, Blanco J, Este JA, Zamzami N, Susin SA, Xie Z, Brothers G, Reed JC, Penninger JM and Kroemer G (2000) Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases. J. Exp. Med. 192: 1081-1092.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1081-1092
-
-
Ferri, K.F.1
Jacotot, E.2
Blanco, J.3
Este, J.A.4
Zamzami, N.5
Susin, S.A.6
Xie, Z.7
Brothers, G.8
Reed, J.C.9
Penninger, J.M.10
Kroemer, G.11
-
42
-
-
0035380462
-
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
-
Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB and Colombini M (2001) Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J. Biol. Chem. 276: 19414-19419.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19414-19419
-
-
Vander Heiden, M.G.1
Li, X.X.2
Gottleib, E.3
Hill, R.B.4
Thompson, C.B.5
Colombini, M.6
-
43
-
-
0034712944
-
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
-
Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M and Thompson CB (2000) Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proc. Natl. Acad. Sci. USA 97: 4666-4671.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4666-4671
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Li, X.X.3
Schumacker, P.T.4
Colombini, M.5
Thompson, C.B.6
-
44
-
-
0043204996
-
VDAC2 inhibits BAK activation and mitochondrial apoptosis
-
Cheng EH, Sheiko TV, Fisher JK, Craigen WJ and Korsmeyer SJ (2003) VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science 301: 513-517.
-
(2003)
Science
, vol.301
, pp. 513-517
-
-
Cheng, E.H.1
Sheiko, T.V.2
Fisher, J.K.3
Craigen, W.J.4
Korsmeyer, S.J.5
-
45
-
-
0034921466
-
Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis
-
Stoebner PE, Carayon P, Casellas P, Portier M, Lavabre-Bertrand T, Cuq P, Cano JP, Meynadier J and Meunier L (2001) Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis. Cell Death Differ. 8: 747-753.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 747-753
-
-
Stoebner, P.E.1
Carayon, P.2
Casellas, P.3
Portier, M.4
Lavabre-Bertrand, T.5
Cuq, P.6
Cano, J.P.7
Meynadier, J.8
Meunier, L.9
-
46
-
-
0037020863
-
Mitochondrial apoptosis and the peripheral benzodiazepine receptor: A novel target for viral and pharmacological manipulation
-
Castedo M, Perfettini JL and Kroemer G (2002) Mitochondrial apoptosis and the peripheral benzodiazepine receptor: A novel target for viral and pharmacological manipulation. J. Exp. Med. 196: 1121-1125.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1121-1125
-
-
Castedo, M.1
Perfettini, J.L.2
Kroemer, G.3
-
47
-
-
9744221185
-
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
-
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB and Hay N (2004) Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol. Cell 16: 819-830.
-
(2004)
Mol. Cell
, vol.16
, pp. 819-830
-
-
Majewski, N.1
Nogueira, V.2
Bhaskar, P.3
Coy, P.E.4
Skeen, J.E.5
Gottlob, K.6
Chandel, N.S.7
Thompson, C.B.8
Robey, R.B.9
Hay, N.10
-
48
-
-
0141863388
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
-
Rathmell JC, Fox CJ, Plas DR, Hammerman PS, Cinalli RM and Thompson CB (2003) Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol. Cell. Biol. 23: 7315-7328.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
Hammerman, P.S.4
Cinalli, R.M.5
Thompson, C.B.6
-
49
-
-
27744491193
-
Emerging functions of mammalian mitochondrial fusion and fission
-
(Spec. no. 2)
-
Chen H and Chan DC (2005) Emerging functions of mammalian mitochondrial fusion and fission. Hum. Mol. Genet 14 (Spec. no. 2): R283-R289.
-
(2005)
Hum. Mol. Genet
, vol.14
-
-
Chen, H.1
Chan, D.C.2
-
50
-
-
16844377411
-
Mitochondrial fusion and fission in the control of apoptosis
-
Perfettini JL, Roumier T and Kroemer G (2005) Mitochondrial fusion and fission in the control of apoptosis. Trends Cell Biol. 15: 179-183.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 179-183
-
-
Perfettini, J.L.1
Roumier, T.2
Kroemer, G.3
-
51
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, Smith CL and Youle RJ (2001) The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev. Cell 1: 515-525.
-
(2001)
Dev. Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
52
-
-
0037164813
-
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
-
Karbowski M, Lee YJ, Gaume B, Jeong SY, Frank S, Nechushtan A, Santel A, Fuller M, Smith CL and Youle RJ (2002) Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J. Cell Biol. 159: 931-938.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 931-938
-
-
Karbowski, M.1
Lee, Y.J.2
Gaume, B.3
Jeong, S.Y.4
Frank, S.5
Nechushtan, A.6
Santel, A.7
Fuller, M.8
Smith, C.L.9
Youle, R.J.10
-
53
-
-
0035844867
-
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
-
Nechushtan A, Smith CL, Lamensdorf I, Yoon SH and Youle RJ (2001) Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J. Cell Biol. 153: 1265-1276.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1265-1276
-
-
Nechushtan, A.1
Smith, C.L.2
Lamensdorf, I.3
Yoon, S.H.4
Youle, R.J.5
-
54
-
-
33644859410
-
Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
-
Delivani P, Adrain C, Taylor RC, Duriez PJ and Martin SJ (2006) Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Mol. Cell 21: 761-773.
-
(2006)
Mol. Cell
, vol.21
, pp. 761-773
-
-
Delivani, P.1
Adrain, C.2
Taylor, R.C.3
Duriez, P.J.4
Martin, S.J.5
-
55
-
-
0035827622
-
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax
-
Cuddeback SM, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C, Singh S and Wang HG (2001) Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J. Biol. Chem. 276: 20559-20565.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20559-20565
-
-
Cuddeback, S.M.1
Yamaguchi, H.2
Komatsu, K.3
Miyashita, T.4
Yamada, M.5
Wu, C.6
Singh, S.7
Wang, H.G.8
-
56
-
-
4644242944
-
Endophilin B1 is required for the maintenance of mitochondrial morphology
-
Karbowski M, Jeong SY and Youle RJ (2004) Endophilin B1 is required for the maintenance of mitochondrial morphology. J. Cell Biol. 166: 1027-1039.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 1027-1039
-
-
Karbowski, M.1
Jeong, S.Y.2
Youle, R.J.3
-
57
-
-
0038490977
-
Microscopic photosensitization: A new tool to investigate the role of mitochondria in cell death
-
Lum MG, Minamikawa T and Nagley P (2002) Microscopic photosensitization: a new tool to investigate the role of mitochondria in cell death. Sci. World J. 2: 1198-1208.
-
(2002)
Sci. World J.
, vol.2
, pp. 1198-1208
-
-
Lum, M.G.1
Minamikawa, T.2
Nagley, P.3
-
58
-
-
0035957969
-
The mitochondrion: Is it central to apoptosis?
-
Finkel E (2001) The mitochondrion: Is it central to apoptosis? Science 292: 624-626.
-
(2001)
Science
, vol.292
, pp. 624-626
-
-
Finkel, E.1
-
59
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
60
-
-
32444434664
-
Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis
-
Lakhani SA, Masud A, Kuida K, Porter Jr GA, Booth CJ, Mehal WZ, Inayat I and Flavell RA (2006) Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis. Science 311: 847-851.
-
(2006)
Science
, vol.311
, pp. 847-851
-
-
Lakhani, S.A.1
Masud, A.2
Kuida, K.3
Porter Jr, G.A.4
Booth, C.J.5
Mehal, W.Z.6
Inayat, I.7
Flavell, R.A.8
-
61
-
-
0033603889
-
Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 calls
-
Finucane DM, Waterhouse NJ, Amarante-Mendes GP, Cotter TG and Green DR (1999) Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 calls. Exp. Cell Res. 251: 166-174.
-
(1999)
Exp. Cell Res.
, vol.251
, pp. 166-174
-
-
Finucane, D.M.1
Waterhouse, N.J.2
Amarante-Mendes, G.P.3
Cotter, T.G.4
Green, D.R.5
-
62
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel E, Newmeyer DD and Green DR (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17: 37-49.
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
|