Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation

Journal of Cellular Physiology

Volumn 227, Issue 6, 2012, Pages 2451-2460

  Dasgupta, Santanu ^a,b   Soudry, Ethan ^a   Mukhopadhyay, Nitai ^b   Shao, Chunbo ^a   Yee, John ^c   Lam, Stephan ^c   Lam, Wan ^c   Zhang, Wei ^d   Gazdar, Adi F ^d   Fisher, Paul B ^b   Sidransky, David ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOCHROME C OXIDASE; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; AGED; ARTICLE; ASIAN; CANCER GROWTH; CANCER INVASION; CAUCASIAN; CELL PROLIFERATION; EXON; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; LUNG CANCER; MALE; NEVER SMOKER LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOKING;

AGED; BRITISH COLUMBIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHI-SQUARE DISTRIBUTION; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINEAR MODELS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; MUTATION; NEOPLASM INVASIVENESS; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RISK ASSESSMENT; RISK FACTORS; SMOKING; SUPEROXIDES; TRANSFECTION;

EID: 84863123131     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22980     Document Type: Article

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