Effects of dairy on metabolic syndrome parameters: A review

Yale Journal of Biology and Medicine

Volumn 87, Issue 2, 2014, Pages 135-147

  Dugan, Christine E ^a   Fernandez, Maria Luz ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Body weight; Calcium; Dairy; Leucine; Metabolic syndrome

Indexed keywords

APOLIPOPROTEIN; BRANCHED CHAIN AMINO ACID; CALCIUM; GLUCOSE; LEUCINE; LIPID; LIPOPROTEIN; MILK PROTEIN; GLUCOSE BLOOD LEVEL;

ARTICLE; BLOOD PRESSURE; CALCIUM INTAKE; DAIRY PRODUCT; DIETARY INTAKE; DYSLIPIDEMIA; FOOD ANALYSIS; FOOD COMPOSITION; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPERTENSION; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; METABOLIC SYNDROME X; MILK; NONHUMAN; NUTRIENT CONCENTRATION; NUTRIENT CONTENT; OBESITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); THERAPY EFFECT; TREATMENT OUTCOME; BLOOD; CHEMICALLY INDUCED; METABOLISM; PATHOPHYSIOLOGY;

ADIPOSITY; BLOOD GLUCOSE; BLOOD PRESSURE; DAIRY PRODUCTS; HUMANS; METABOLIC SYNDROME X; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84902119592     PISSN: 00440086     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (85)

1. Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab. 2007:92(2):399-404.
2. Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Final report. Circulation. 2002;106(25):3143-421.
3. Burton WN, Chen CY, Schultz AB, Edington DW. The prevalence of metabolic syndrome in an employed population and the impact on health and productivity. J Occup Environ Med. 2008;50(10):1139-48.
4. Chen SH, He F, Zhou HL, Wu HR, Xia C, Li YM. Relationship between nonalcoholic fatty liver disease and metabolic syndrome. J Dig Dis. 2011;12(2):125-30.
5. Isomaa B, Almgren P, Tuomi T, Forsen B, Lahti K, Nissen M, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care. 2001;24(4):683-9.
6. Ford ES, Li C, Zhao G. Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US. J Diabetes. 2010;2(3):180-93.
7. Ford ES, Li C, Sattar N. Metabolic syndrome and incident diabetes: Current state of the evidence. Diabetes Care. 2008;31(19):1898-1904.
8. Grundy SM. Does a diagnosis of metabolic syndrome have value in clinical practice? Am J Clin Nutr. 2006;83(6):1248-51.
9. Grundy SM. Metabolic syndrome: A multiplex cardiovascular risk factor. J Clin Endocrinol Metab. 2007;92(2):399-404.
10. Al-Sarraj T, Saadi H, Calle MC, Volek JS, Fernandez ML. Carbohydrate restriction as a first-line dietary intervention therapy effectively reduces the biomarkers of metabolic syndrome in Emirati adults. J Nutrition. 2009;139(9):1667-76.
11. Jones JL, Fernandez ML, McIntosh M, Najm W, Calle MC, Kalynych C, et al. A Mediterranean-style low-glycemic-load diet improves variables of metabolic syndrome in women, and addition of a phytochemical-rich medical food enhances benefits on lipoprotein metabolism. J Clin Lipidol. 2011;5(3):188-96.
12. Klemsdal TO, Holme I, Nerland H, Pedersen TR, Tonstad S. Effects of a low glycemic load diet versus a low-fat diet in subjects with and without the metabolic syndrome. Nutr Metab Cardiovasc Dis. 2010;20(3):195-201.
13. Blesso CN, Andersen CJ, Barona J, Volk B, Volek JS, Fernandez ML. Effects of carbohydrate restriction and dietary cholesterol provided by eggs on clinical risk factors of metabolic syndrome. J Clin Lipidol. 2013;7(5):463-71.
14. Andersen CJ, Fernandez ML. Dietary approaches to improving atheroprotective HDL functions. Food and Function. 2013;14(3):241-54.
15. Volek JS, Phinney SD, Forsythe CE, Quann EE, Wood RJ, Puglisi MJ, et al. Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low fat diet. Lipids. 2009;44(4):297-309.
16. Volek JS, Fernandez ML, Feinman RD, Phinney SD. Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome. Prog Lipid Res. 2008;47(5):307-18.
17. Kesse-Guyot E, Ahluwalia N, Lassale C, Hercberg S, Fezeu L, Lairon D. Adherence to Mediterranean diet reduces the risk of metabolic syndrome: A 6-year prospective study. Nutr Metab Cardiovasc Dis. 2013;23(7):677-83.
18. Blesso CN, Andersen CJ, Barona J, Volek J, Fernandez ML. Whole egg consumption improves lipoprotein profiles and insulin sensitivity in individuals with metabolic syndrome. Metabolism. 2013;62(3):400-10.
19. German JB, Dillard CJ. Composition, structure and absorption of milk lipids: A source of energy, fat-soluble nutrients and bioactive molecules. Crit Rev Food Sci Nutr. 2006;46(1):57-92.
20. Miller G, Jarvis J, McBean L, editors. Handbook of Dairy Foods and Nutrition. Boca Raton, FL: CRC Press LLC; 2000.
21. Molkentin J. Occurrence and biochemical characteristics of natural bioactive substances in bovine milk lipids. Br J Nutr. 2000;84(Suppl 1):S47-53.
22. Dougkas A, Reynolds CK, Givens ID, Elwood PC, Minihane AM. Associations between dairy consumption and body weight: A review of the evidence and underlying mechanisms. Nutr Res Rev. 2011;24(1):72-95.
23. U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2010. 7th edition. Washington, DC: U.S. Government Printing Office; 2010.
24. Fulgoni VL,3rd, Huth PJ, DiRienzo DB, Miller GD. Determination of the optimal number of dairy servings to ensure a low prevalence of inadequate calcium intake in Americans. J Am Coll Nutr. 2004;23(6):651-9.
25. Mangano KM, Walsh SJ, Insogna KL, Kenny AM, Kerstetter JE. Calcium intake in the United States from dietary and supplemental sources across adult age groups: New estimates from the National Health and Nutrition Examination Survey 2003-2006. J Am Diet Assoc. 2011;111(5):687-95.
26. Dietary intakes for adults 20 years of age and older. Centers for Disease Control and Prevention [Internet]. Available from: http://www.cdc.gov/nchs/fastats/diet.htm.
27. McCarron DA, Heaney RP. Estimated healthcare savings associated with adequate dairy food intake. Am J Hypertens. 2004;17(1):88-97.
28. Pereira MA, Jacobs DR Jr., Van Horn L, Slattery ML, Kartashov AI, Ludwig DS. Dairy consumption, obesity, and the insulin resistance syndrome in young adults: The CARDIA Study. JAMA. 2002;287(16):2081-9.
29. Fumeron F, Lamri A, Emery N, Bellili N, Jaziri R, Porchay-Balderelli I, et al. DESIR Study Group: Dairy products and the metabolic syndrome in a prospective study, DESIR. J Am Coll Nutr. 2011;30(5 Suppl 1):454S-63S.
30. Elwood PC, Pickering JE, Fehily AM. Milk and dairy consumption, diabetes and the metabolic syndrome: The Caerphilly prospective study. J Epidemiol Community Health. 2007;61(8):695-98.
31. Tremblay A, Gilbert JA. Milk products, insulin resistance syndrome and type 2 diabetes. J Am Coll Nutr. 2009;28(Suppl 1):91S-102S.
32. Lawlor DA, Ebrahim S, Timpson N, Davey Smith G. Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: Findings from the British Women's Heart and Health Study. Diabet Med. 2005;22(7):808-11.
33. Snijder MB, van der Heijden AA, van Dam RM, Stehouwer CD, Hiddink GJ, Nijpels G, et al. Is higher dairy consumption associated with lower body weight and fewer metabolic disturbances? The Hoorn Study. Am J Clin Nutr. 2007;85(4):989-95.
34. Beydoun MA, Gary TL, Caballero BH, Lawrence RS, Cheskin LJ, Wang Y. Ethnic differences in dairy and related nutrient consumption among US adults and their association with obesity, central obesity, and the metabolic syndrome. Am J Clin Nutr. 2008;87(6):1914-25.
35. Shin H, Yoon YS, Lee Y, Kim CI, Oh SW. Dairy product intake is inversely associated with metabolic syndrome in korean adults: anseong and ansan cohort of the korean genome and epidemiology study. J Korean Med Sci. 2013;28(10):1482-8.
36. Zemel MB, Richards J, Milstead A, Campbell P. Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res. 2005;13(7):1218-25.
37. Dugan CE, Barona J, Fernandez ML. Increased dairy consumption differentially improves metabolic syndrome markers in male and female adult. Met Synd Rel Dis. 2013. Epub ahead of print.
38. van Meijl LE, Mensink RP. Low-fat dairy consumption reduces systolic blood pressure, but does not improve other metabolic risk parameters in overweight and obese subjects. Nutr Metab Cardiovasc Dis. 2011;21(5):355-61.
39. Stancliffe RA, Thorpe T, Zemel MB. Dairy attentuates oxidative and inflammatory stress in metabolic syndrome. Am J Clin Nutr. 2011;94(2):422-30.
40. Van Loan MD, Keim NL, Adams SH, Souza E, Woodhouse LR, Thomas A, et al. Dairy foods in a moderate energy restricted diet do not enhance central fat, weight, and intra-abdominal adipose tissue losses nor reduce adipocyte size or inflammatory markers in overweight and obese adults: A controlled feeding study. J Obes. Epub 2011 Sep 14.
41. Shin MJ, Hyun YJ, Kim OY, Kim JY, Jang Y, Lee JH. Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women. Int J Obes. 2006;30:1529-34.
42. Vaskonen T. Dietary minerals and modification of cardiovascular risk factors. J Nutr Biochem. 2003;14(9):492-506.
43. van Meijl LE, Vrolix R, Mensink RP. Dairy product consumption and the metabolic syndrome. Nutr Res Rev. 2008;21(2):148-57
44. Shils M, Shike M, Ross C, Carballero B, Cousins R, editors. Modern Nutrition in Health and Disease. 10th edition. Baltimore: Lippincott Williams & Wilkins; 2006.
45. Zemel MB. Mechanisms of dairy modulation of adiposity. J Nutr. 2003;133(1):252S-6S.
46. Zemel MB, Shi H, Greer B, Dirienzo D, Zemel PC. Regulation of adiposity by dietary calcium. FASEB J. 2000:14(9):1132-8.
47. Shi H, Norman AW, Okamura WH, Sen A, Zemel MB. 1alpha,25-Dihydroxyvitamin D3 modulates human adipocyte metabolism via nongenomic action. FASEB J. 2001;15(14):2751-3.
48. Bortolotti M, Rudelle S, Schneiter P, Vidal H, Loizon E, Tappy L, et al. Dairy calcium supplementation in overweight or obese persons: Its effect on markers of fat metabolism. Am J Clin Nutr. 2008;88(4):877-85.
49. Parikh SJ, Edelman M, Uwaifo GI, Freedman RJ, Semega-Janneh M, Reynolds J, et al. The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults. J Clin Endocrinol Metab. 2004;89(3):1196-9.
50. Ganji V, Zhang X, Shaikh N, Tangpricha V. Serum 25-hydroxyvitamin D concentrations are associated with prevalence of metabolic syndrome and various cardiometabolic risk factors in US children and adolescents based on assay-adjusted serum 25-hydroxyvitamin D data from NHANES 2001-2006. Am J Clin Nutr. 2011;94(1):225-33.
51. Oosterwerff MM, Eekhoff EM, Heymans MW, Lips P, van Schoor NM. Serum 25-hydroxyvitamin D levels and the metabolic syndrome in older persons: A population-based study. Clin Endocrinol (Oxf). 2011;75(5):608-13.
52. Zemel MB. Calcium modulation of hypertension and obesity: mechanisms and implications. J Am Coll Nutr. 2001;20(5):428S-35S; discussion 440S-42S.
53. Kris-Etherton PM, Grieger JA, Hilpert KF, West SG. Milk products, dietary patterns and blood pressure management. J Am Coll Nutr. 2009;28(Suppl 1):103S-19S.
54. Berne R, Levy M, Koeppen B, Stanton B. Physiology. St. Louis, MI: Mosby; 2004.
55. Brown NJ, Vaughan DE. Angiotensin-converting enzyme inhibitors. Circulation. 1998;97(14):1411-20.
56. Fitzgerald RJ, Meisel H. Milk protein-derived peptide inhibitors of angiotensin-I-converting enzyme. Br J Nutr. 2000;84(Suppl 1):S33-7.
57. Yamamoto N. Antihypertensive peptides derived from food proteins. Biopolymers. 1997;43(5):129-34.
58. Yamasue K, Morikawa N, Mizushima S, Tochikubo O. The blood pressure lowering effect of lactotripeptides and salt intake in 24-h ambulatory blood pressure measurements. Clin Exp Hypertens. 2010;32(4):214-20.
59. van der Zander K, Bots ML, Bak AA, Koning MM, de Leeuw PW. Enzymatically hydrolyzed lactotripeptides do not lower blood pressure in mildly hypertensive subjects. Am J Clin Nutr. 2008;88(6):1697-702.
60. Pal S, Ellis V. The chronic effects of whey proteins on blood pressure, vascular function, and inflammatory markers in overweight individuals. Obesity. 2010;18(7):1354-9.
61. McCarron DA, Reusser ME. Finding consensus in the dietary calcium-blood pressure debate. J Am Coll Nutr. 1999;18(5 Suppl):398S-405S.
62. Ruidavets JB, Bongard V, Simon C, Dallongeville J, Ducimetiere P, Arveiler D, et al. Independent contribution of dairy products and calcium intake to blood pressure variations at a population level. J Hypertens. 2006;24(4):671-81.
63. Ralston RA, Lee JH, Truby H, Palermo CE, Walker KZ. A systematic review and metaanalysis of elevated blood pressure and consumption of dairy foods. J Hum Hypertens. 2012;26(1):3-13.
64. Xu JY, Qin LQ, Wang PY, Li W, Chang C. Effect of milk tripeptides on blood pressure: A meta-analysis of randomized controlled trials. Nutrition. 2008:24(10):933-40.
65. Pripp AH. Effect of peptides derived from food proteins on blood pressure: a metaanalysis of randomized controlled trials. Food Nutr Res. 2008;52.
66. Gannon MC, Nuttall FQ. Amino acid ingestion and glucose metabolism-a review. IUBMB Life. 2010;62(9):660-8.
67. Graf S, Egert S, Heer M. Effects of whey protein supplements on metabolism: evidence from human intervention studies. Curr Opin Clin Nutr Metab Care. 2011;14(6):569-80.
68. Frid AH, Nilsson M, Holst JJ, Bjorck IM. Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects. Am J Clin Nutr. 2005;82(1):69-75.
69. Manders RJ, Wagenmakers AJ, Koopman R, Zorenc AH, Menheere PP, Schaper NC, et al. Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes. Am J Clin Nutr. 2005;82(1):76-83.
70. Layman DK, Shiue H, Sather C, Erickson DJ, Baum J. Increased dietary protein modifies glucose and insulin homeostasis in adult women during weight loss. J Nutr. 2003;133(2):405-10.
71. Layman DK, Boileau RA, Erickson DJ, Painter JE, Shiue H, Sather C, et al. A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. J Nutr. 2003;133(2):411-7.
72. Melnik BC. Leucine signaling in the pathogenesis of type 2 diabetes and obesity. World J Diabetes. 2012;3(3):38-53.
73. Macotela Y, Emanuelli B, Bang AM, Espinoza DO, Boucher J, Beebe K, et al. Dietary leucine-an environmental modifier of insulin resistance acting on multiple levels of metabolism. PLoS One. 2011;6(6):e21187.
74. Siri-Tarino PW, Sun Q, Hu FB, Krauss RM. Saturated fat, carbohydrate, and cardiovascular disease. Am J Clin Nutr. 2010;91(3):502-9.
75. Elwood PC, Pickering JE, Givens DI, Gallacher JE. The consumption of milk and dairy foods and the incidence of vascular disease and diabetes: an overview of the evidence. Lipids. 2010;45(10):925-39.
76. Yacowitz H, Fleischman AI, Bierenbaum ML. Effects of oral calcium upon serum lipids in man. Br Med J. 1965;1(5446):1352-54.
77. Denke MA, Fox MM, Schulte MC. Shortterm dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men. J Nutr. 1993;123(6):1047-53.
78. Govers MJ, Termont DS, Lapre JA, Kleibeuker JH, Vonk RJ, Van der Meer R. Calcium in milk products precipitates intestinal fatty acids and secondary bile acids and thus inhibits colonic cytotoxicity in humans. Cancer Res. 1996;56(14):3270-75.
79. Christensen R, Lorenzen JK, Svith CR, Bartels EM, Melanson EL, Saris WH, et al. Effect of calcium from dairy and dietary supplements on faecal fat excretion: a metaanalysis of randomized controlled trials. Obes Rev. 2009;10(4):475-86.
80. Hunter JE, Zhang J, Kris-Etherton PM. Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review. Am J Clin Nutr. 2010;91(1):46-63.
81. Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr. 2003;77(5):1146-55.
82. Noh SK, Koo SI. Milk sphingomyelin is more effective than egg sphingomyelin in inhibiting intestinal absorption of cholesterol and fat in rats. J Nutr. 2004;134(10):2611-6.
83. Kamili A, Wat E, Chung RW, Tandy S, Weir JM, Meikle PJ, et al. Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids. Nutr Metab (Lond). 2010;7:90.
84. Ballard KD, Mah E, Guo Y, Pei R, Volek JS, Bruno RS. Low-fat milk ingestion prevents postprandial hyperglycemia-mediated impairments in vascular endothelial function in obese individuals with metabolic syndrome. J Nutr. 2013;143(10):1602-10.
85. Kalergis M, Leung Yinko SS, Nedelcu R. Dairy products and prevention of type 2 diabetes: Implications for research and practice. Front Endocrinol (Lausanne). 2013;23(4):90.