Dairy calcium supplementation in overweight or obese persons: Its effect on markers of fat metabolism

American Journal of Clinical Nutrition

Volumn 88, Issue 4, 2008, Pages 877-885

  Bortolotti, Murielle ^a   Rudelle, Servane ^a   Schneiter, Philippe ^a   Vidal, Hubert ^b   Loizon, Emmanuelle ^b   Tappy, Luc ^a   Acheson, Kevin J ^c  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITÉ DE LYON   (France)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BIOLOGICAL MARKER; CAFFEINE; CALCIUM; FATTY ACID; GLYCEROL; LACTOSE; OSTEOCALCIN; PLACEBO;

ABDOMINAL FAT ASPIRATION BIOPSY; ABDOMINAL SUBCUTANEOUS FAT; ADIPOSE TISSUE; ADULT; ARTICLE; CALCIUM EXCRETION; CALCIUM INTAKE; CALCIUM URINE LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIALYSATE LEVEL; DIET SUPPLEMENTATION; ENERGY CONSUMPTION; ENERGY EXPENDITURE; FATTY ACID BLOOD LEVEL; FEMALE; GENE EXPRESSION; GLYCEROL BLOOD LEVEL; HUMAN; LIPID METABOLISM; LIPID OXIDATION; LIPID PEROXIDATION; LIPOGENESIS; LUNG GAS EXCHANGE; MALE; MICRODIALYSIS; OBESITY; RANDOMIZED CONTROLLED TRIAL;

EID: 53849083103     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/88.4.877     Document Type: Article

References (46)

1. Jones BH, Kim JH, Zemel MB, et al. Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity. Am J Physiol 1996;270:E192-6.
2. Xue B, Moustaid N, Wilkison WO, Zemel MB. The agouti gene product inhibits lipolysis in human adipocytes via a Ca2+-dependent mechanism. FASEB J 1998;12:1391-6.
3. Kim JH, Mynatt RL, Moore JW, Woychik RP, Moustaid N, Zemel MB. The effects of calcium channel blockade on agouti-induced obesity. FASEB J 1996;10:1646-52.
4. Kim JH, Kiefer LL, Woychik RP, et al. Agouti regulation of intracellular calcium: role of melanocortin receptors. Am J Physiol 1997;272:E379-84.
5. Shi H, Dirienzo D, Zemel MB. Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2-agouti transgenic mice. FASEB J 2001;15:291-3.
6. Xue B, Greenberg AG, Kraemer FB, Zemel MB. Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes. FASEB J 2001;15:2527-9.
7. Zemel MB, Shi H, Greer B, Dirienzo D, Zemel PC. Regulation of adiposity by dietary calcium. FASEB J 2000;14:1132-8.
8. Zemel MB. Calcium modulation of hypertension and obesity: mechanisms and implications. J Am Coll Nutr 2001;20:428S-35S.
9. Bjomtorp P, Sjostrom L. Carbohydrate storage in man: speculations and some quantitative considerations. Metabolism 1978;27:1853-65.
10. Weiss L, Hoffmann GE, Schreiber R, et al. Fatty-acid biosynthesis in man, a pathway of minor importance. Purification, optimal assay conditions, and organ distribution of fatty-acid synthase. Biol Chem Hoppe Seyler 1986;367:905-12.
11. Angel A, Bray GA. Synthesis of fatty acids and cholesterol by liver, adipose tissue and intestinal mucosa from obese and control patients, Eur J Clin Invest 1979;9:355-62.
12. Hoffmann GE, Andres H, Weiss L, Kreisel C, Sander R. Properties and organ distribution of ATP citrate (pro-3S)-lyase. Biochim Biophys 1980;620:151-8,
13. Mellati AM, Beck JC, Dupre J, Rubinstein D. Conversion of glucose to lipid by human adipose tissue in vitro. Metabolism 1970;19:988-94.
14. Barter PJ, Nestel PJ, Carroll KF. Precursors of plasma triglyceride fatty acid in humans. Effects of glucose consumption, clofibrate administration, and alcoholic fatty liver. Metabolism 1972;21:117-24.
15. Patel MS, Owen OE, Goldman LI, Hanson RW. Fatty acid synthesis by human adipose tissue. Metabolism 1975;24:161-73.
16. Sjostrom L. Carbohydrate-stimulated fatty acid synthesis de novo in human adipose tissue of different cellular types. Acta Med Scand 1973; 194:387-404.
17. Guo ZK, Cella LK, Baum C, Ravussin E, Schoeller DA. De novo lipogenesis in adipose tissue of lean and obese women: application of deuterated water and isotope ratio mass spectrometry. Int J Obes Relat Metab Disord 2000;24:932-7.
18. Xue BZ, Wilkison WO, Mynatt RL, Moustaid N, Goldman M, Zemel MB. The agouti gene product stimulates pancreatic [beta]-cell Ca2+ signaling and insulin release. Physiol Genomics 1999; 1:11-9.
19. Zemel MB. Regulation of adiposity and obesity risk by dietary calcium: mechanisms and implications. J Am Coll Nutr 2002;21:146S-51S.
20. Zemel MB, Thompson W, Milstead A, Moms K, Campbell P. Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 2004; 12:582-90.
21. Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L, Silva E. Dairy augmentation of total and central fat loss in obese subjects. Int I Obes (Lond) 2005;29:391-7.
22. Zemel MB, Richards J, Milstead A, Campbell P. Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res 2005;13:1218-25.
23. Melanson EL, Sharp TA, Schneider I, Donahoo WT, Grunwald GK, Hill JO. Relation between calcium intake and fat oxidation in adult humans. Int J Obes Relat Metab Disord 2003;27:196-203.
24. Shahkhalili Y, Murset C, Meirim I, et al. Calcium supplementation of chocolate: effect on cocoa butter digestibility and blood lipids in humans. Am J Clin Nutr 2001;73:246-52.
25. Denke MA, Fox MM, Schulte MC. Short-term dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men. I Nutr 1993;123:1047-53.
26. Jacobsen R, Lorenzen JK, Toubro S, Krog-Mikkelsen I, Astrup A. Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes (Lond) 2005;29:292-301.
27. Welberg JW, Monkelbaan JF, de Vries EG, et al. Effects of supplemental dietary calcium on quantitative and qualitative fecal fat excretion in man. Ann Nutr Metab 1994;38:185-91.
28. Astrup A, Toubro S, Cannon S, Hein P, Breu m L, Madsen J. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am I Clin Nutr 1990; 51:759-67.
29. Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jequier E. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr 1980;33:989-97.
30. Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr 1989;49:44-50.
31. Ducluzeau PH, Perretti N, Laville M, et al. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 2001;50:1134-42.
32. Henry S, Trueb L, Sartori C, Scherrer U, Jequier E, Tappy L. Effects of a sympathetic activation by a lower body negative pressure on glucose and lipid metabolism. Clin Physiol 1998; 18:562-9.
33. Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr 2004;79: 40-6.
34. Lonnroth P, Jansson PA, Smith U. A microdialysis method allowing characterization of intercellular water space in humans. Am J Physiol 1987;253:E228-31.
35. Livesey G, Elia M. Estimation of energy expenditure, net carbohydrate utilization, and net fat oxidation and synthesis by indirect calorimetry: evaluation of errors with special reference to the detailed composition of fuels. Am J Clin Nutr 1988;47:608-28.
36. Lorenzen JK, Molgaard C, Michaelsen KF, Astrup A. Calcium supplementation for 1 y does not reduce body weight or fat mass in young girls. Am J Clin Nutr 2006;83:18-23.
37. Melanson EL, Donahoo WT, Dong F, Ida T, Zemel MB. Effect of lowand high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res 2005;13:2102-12.
38. Carafoli E. Calcium signaling: a tale for all seasons. Proc Natl Acad Sci USA 2002;99:1115-22.
39. Denton RM, McCormack JG. Ca2+ as a second messenger within mitochondria of the heart and other tissues. Annu Rev Physiol 1990;52: 451-66.
40. Boon N, Hul GB, Stegen JH, et al. An intervention study of the effects of calcium intake on faecal fat excretion, energy metabolism and adipose tissue mRNA expression of lipid-metabolism related proteins. Int J Obes (Lond) 2007;31:1704-12.
41. Boon N, Hul GB, Sicard A, et al. The effects of increasing serum calcitriol on energy and fat metabolism and gene expression. Obesity (Silver Spring) 2006; 14:1739-46.
42. National Library of Medicine. Drug information: calcitriol. Medline Plus: medical encyclopedia. Version current: 19 December 2008. Internet: http://www.nlm.nih.gov/medlineplus/print/druginfo/medmaster/a682335.html (accessed 24 Dec 2007).
43. Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr 2000;72:690-3.
44. Mathieu C, Gysemans C, Giulietti A, Bouillon R. Vitamin D and diabetes. Diabetologia 2005;48:1247-57.
45. Yanoff LB, Parikh SJ, Spitalnik A, et al. The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese black Americans. Clin Endocrinol (Oxf) 2006;64:523-9.
46. Parikh SJ, Edelman M, Uwaifo GI, et al. The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults. J Clin Endocrinol Metab 2004; 89:1196-9.