-
2
-
-
0036746010
-
The clonal theory of parasitic protozoa: 12 Years on
-
Tibayrenc M, Ayala FJ (2002) The clonal theory of parasitic protozoa: 12 years on. Trends Parasitol 18: 405-410.
-
(2002)
Trends Parasitol
, vol.18
, pp. 405-410
-
-
Tibayrenc, M.1
Ayala, F.J.2
-
3
-
-
84878198590
-
How clonal are Trypanosoma and Leishmania?
-
Tibayrenc M, Ayala FJ (2013) How clonal are Trypanosoma and Leishmania? Trends Parasitol 29: 264-269.
-
(2013)
Trends Parasitol
, vol.29
, pp. 264-269
-
-
Tibayrenc, M.1
Ayala, F.J.2
-
4
-
-
0034071224
-
Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: A multilocus enzyme electrophoresis approach
-
DOI 10.1017/S0031182099005661
-
Barnabé C, Brisse S, Tibayrenc M (2000) Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach. Parasitology 120 (Pt 5): 513-526. (Pubitemid 30261023)
-
(2000)
Parasitology
, vol.120
, Issue.5
, pp. 513-526
-
-
Barnabe, C.1
Brisse, S.2
Tibayrenc, M.3
-
5
-
-
0033954610
-
Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis
-
DOI 10.1016/S0020-7519(99)00168-X, PII S002075199900168X
-
Brisse S, Barnabé C, Tibayrenc M (2000) Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. Int J Parasitol 30: 35-44. (Pubitemid 30089720)
-
(2000)
International Journal for Parasitology
, vol.30
, Issue.1
, pp. 35-44
-
-
Brisse, S.1
Barnabe, C.2
Tibayrenc, M.3
-
6
-
-
84857655347
-
The revised Try-panosoma cruzi subspecific nomenclature: Rationale, epidemiological relevance and research applications
-
Zingales B, Miles MA, Campbell DA, Tibayrenc M, Macedo AM, et al. (2012) The revised Try-panosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infect Genet Evol 12: 240-253.
-
(2012)
Infect Genet Evol
, vol.12
, pp. 240-253
-
-
Zingales, B.1
Miles, M.A.2
Campbell, D.A.3
Tibayrenc, M.4
Macedo, A.M.5
-
8
-
-
31544467265
-
Two hybridization events define the population structure of Trypanosoma cruzi
-
DOI 10.1534/genetics.104.038745
-
Westenberger SJ, Barnabé C, Campbell DA, Sturm NR (2005) Two hybridization events define the population structure of Trypanosoma cruzi. Genetics 171: 527-543. (Pubitemid 43156444)
-
(2005)
Genetics
, vol.171
, Issue.2
, pp. 527-543
-
-
Westenberger, S.J.1
Barnabe, C.2
Campbell, D.A.3
Sturm, N.R.4
-
9
-
-
84855998981
-
Analyses of 32 loci clarify phylogenetic relationships among Trypanosoma cruzi lineages and support a single hybridization prior to human contact
-
Flores López CA, Machado CA (2011) Analyses of 32 loci clarify phylogenetic relationships among Trypanosoma cruzi lineages and support a single hybridization prior to human contact. PLoS Negl Trop Dis 5: e1272.
-
(2011)
PLoS Negl Trop Dis
, vol.5
-
-
Flores López, C.A.1
Machado, C.A.2
-
10
-
-
80055084610
-
Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids
-
Lewis MD, Llewellyn MS, Yeo M, Acosta N, Gaunt MW, et al. (2011) Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids. PLoS Negl Trop Dis 5: e1363.
-
(2011)
PLoS Negl Trop Dis
, vol.5
-
-
Lewis, M.D.1
Llewellyn, M.S.2
Yeo, M.3
Acosta, N.4
Gaunt, M.W.5
-
11
-
-
0038326937
-
Trypanosoma cruzi clonal diversity and the epidemiology of Chagas' disease
-
DOI 10.1016/S1286-4579(03)00050-9
-
Buscaglia CA, Di Noia JM (2003) Trypanosoma cruzi clonal diversity and the epidemiology of Chagas' disease. Microbes Infect 5: 419-427. (Pubitemid 36549184)
-
(2003)
Microbes and Infection
, vol.5
, Issue.5
, pp. 419-427
-
-
Buscaglia, C.A.1
Di, N.J.M.2
-
12
-
-
0033835153
-
Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic chagas disease: Differential distribution of genetic types into diverse organs
-
Vago AR, Andrade LO, Leite AA, d'Avila Reis D, Macedo AM, et al. (2000) Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic Chagas disease: differential distribution of genetic types into diverse organs. Am J Pathol 156: 1805-1809. (Pubitemid 30646718)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.5
, pp. 1805-1809
-
-
Vago, A.R.1
Andrade, L.O.2
Leite, A.A.3
D'Avila, R.D.4
Macedo, A.M.5
Adad, S.J.6
Tostes Jr., S.7
Moreira, M.D.C.V.8
Brasilerio Filho, G.9
Pena, S.D.J.10
-
13
-
-
0032940097
-
Differential tissue distribution of diverse clones of Trypanosoma cruzi in infected mice
-
DOI 10.1016/S0166-6851(99)90035-X, PII S016668519990035X
-
Andrade LO, Machado CR, Chiari E, Pena SD, Macedo AM (1999) Differential tissue distribution of diverse clones of Trypanosoma cruzi in infected mice. Mol Biochem Parasitol 100: 163-172. (Pubitemid 29236027)
-
(1999)
Molecular and Biochemical Parasitology
, vol.100
, Issue.2
, pp. 163-172
-
-
Andrade, L.O.1
Machado, C.R.S.2
Chiari, E.3
Pena, S.D.J.4
Macedo, A.M.5
-
14
-
-
77958010248
-
Differential tissue tropism of Trypanosoma cruzi strains: An in vitro study
-
Andrade LO, Galvão LMC, Meirelles MdNSL, Chiari E, Pena SDJ, et al. (2010) Differential tissue tropism of Trypanosoma cruzi strains: an in vitro study. Mem Inst Oswaldo Cruz 105: 834-837.
-
(2010)
Mem Inst Oswaldo Cruz
, vol.105
, pp. 834-837
-
-
Andrade, L.O.1
Galvão, L.M.C.2
Meirelles, Md.N.S.L.3
Chiari, E.4
Pena, S.D.J.5
-
16
-
-
69049116505
-
Ergosterol biosynthesis and drug development for Chagas disease
-
Urbina JA (2009) Ergosterol biosynthesis and drug development for Chagas disease. Mem Inst Oswaldo Cruz 104 Suppl 1: 311-318.
-
(2009)
Mem Inst Oswaldo Cruz
, vol.104
, Issue.SUPPL. 1
, pp. 311-318
-
-
Urbina, J.A.1
-
17
-
-
84873136488
-
Trypanosoma cruzi response to sterol biosynthesis inhibitors: Morphophysiological alterations leading to cell death
-
Kessler RL, Soares MJ, Probst CM, Krieger MA (2013) Trypanosoma cruzi response to sterol biosynthesis inhibitors: morphophysiological alterations leading to cell death. PLoS One 8: e55497.
-
(2013)
PLoS One
, vol.8
-
-
Kessler, R.L.1
Soares, M.J.2
Probst, C.M.3
Krieger, M.A.4
-
18
-
-
9444291409
-
Cure of short- and long-term experimental Chagas' disease using D0870
-
Urbina JA, Payares G, Molina J, Sanoja C, Liendo A, et al. (1996) Cure of short- and long-term experimental Chagas' disease using D0870. Science 273: 969-971. (Pubitemid 26275176)
-
(1996)
Science
, vol.273
, Issue.5277
, pp. 969-971
-
-
Urbina, J.A.1
Payares, G.2
Molina, J.3
Sanoja, C.4
Liendo, A.5
Lazardi, K.6
Piras, M.M.7
Piras, R.8
Perez, N.9
Wincker, P.10
Ryley, J.F.11
-
19
-
-
0242361260
-
Cloning and analysis of Trypanosoma cruzi lanosterol 14a-demethylase
-
DOI 10.1016/j.molbiopara.2003.07.004
-
Buckner FS, Joubert BM, Boyle SM, Eastman RT, Verlinde CLMJ, et al. (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14a-demethylase. Mol Biochem Parasitol 132: 75-81. (Pubitemid 37352903)
-
(2003)
Molecular and Biochemical Parasitology
, vol.132
, Issue.2
, pp. 75-81
-
-
Buckner, F.S.1
Joubert, B.M.2
Boyle, S.M.3
Eastman, R.T.4
Verlinde, C.L.M.J.5
Matsuda, S.P.T.6
-
20
-
-
33646765351
-
Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors
-
DOI 10.1016/j.ijantimicag.2005.12.012, PII S0924857906000823
-
Silva DT, de Meirelles MdNSL, Almeida D, Urbina JA, Pereira MCS (2006) Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors. Int J Antimicrob Agents 27: 530-537. (Pubitemid 43767077)
-
(2006)
International Journal of Antimicrobial Agents
, vol.27
, Issue.6
, pp. 530-537
-
-
Silva, D.T.1
De Meirelles, M.D.N.S.L.2
Almeida, D.3
Urbina, J.A.4
Pereira, M.C.S.5
-
21
-
-
79960975304
-
Targeting Trypanosoma cruzi sterol 14a-demethylase (CYP51)
-
Lepesheva GI, Villalta F, Waterman MR (2011) Targeting Trypanosoma cruzi sterol 14a-demethylase (CYP51). Adv Parasitol 75: 65-87.
-
(2011)
Adv Parasitol
, vol.75
, pp. 65-87
-
-
Lepesheva, G.I.1
Villalta, F.2
Waterman, M.R.3
-
22
-
-
84871574115
-
Recent Developments in Sterol 14-demethylase Inhibitors for Chagas Disease
-
Buckner FS, Urbina JA (2012) Recent Developments in Sterol 14-demethylase Inhibitors for Chagas Disease. Int J Parasitol Drugs Drug Resist 2: 236-242.
-
(2012)
Int J Parasitol Drugs Drug Resist
, vol.2
, pp. 236-242
-
-
Buckner, F.S.1
Urbina, J.A.2
-
23
-
-
0025020543
-
Inhibition of Trypanosoma cruzi growth and sterol biosynthesis by lovastatin
-
DOI 10.1016/0006-291X(90)91028-Q
-
Florin Christensen M, Florin Christensen J, Garin C, Isola E, Brenner RR, et al. (1990) Inhibition of Trypanosoma cruzi growth and sterol biosynthesis by lovastatin. Biochem Biophys Res Commun 166: 1441-1445. (Pubitemid 20069002)
-
(1990)
Biochemical and Biophysical Research Communications
, vol.166
, Issue.3
, pp. 1441-1445
-
-
Florin-Christensen, M.1
Florin-Christensen, J.2
Garin, C.3
Isola, E.4
Brenner, R.R.5
Rasmussen, L.6
-
24
-
-
0027413385
-
Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: In vitro and in vivo studies
-
Urbina JA, Lazardi K, Marchan E, Visbal G, Aguirre T, et al. (1993) Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies. Antimicrob Agents Chemother 37: 580-591. (Pubitemid 23072606)
-
(1993)
Antimicrobial Agents and Chemotherapy
, vol.37
, Issue.3
, pp. 580-591
-
-
Urbina, J.A.1
Lazardi, K.2
Marchan, E.3
Visbal, G.4
Aguirre, T.5
Piras, M.M.6
Piras, R.7
Maldonado, R.A.8
Payares, G.9
De Souza, W.10
-
25
-
-
0037116593
-
Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase
-
DOI 10.1016/S0014-5793(01)03238-0, PII S0014579301032380
-
Hurtado-Guerrrero R, Peña-Díaz J, Montalvetti A, Ruiz-Pérez LM, González-Pacanowska D (2002) Kinetic properties and inhibition of trypanosoma cruzi 3-hydroxy-3-methylglutaryl coa reductase. FEBS Lett 510: 141-144. (Pubitemid 34093813)
-
(2002)
FEBS Letters
, vol.510
, Issue.3
, pp. 141-144
-
-
Hurtado-Guerrrero, R.1
Pea-Diaz, J.2
Montalvetti, A.3
Ruiz-Perez, L.M.4
Gonzalez-Pacanowska, D.5
-
26
-
-
79953227657
-
Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1- bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
-
Rosso VS, Szajnman SH, Malayil L, Galizzi M, Moreno SNJ, et al. (2011) Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem 19: 2211-2217.
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 2211-2217
-
-
Rosso, V.S.1
Szajnman, S.H.2
Malayil, L.3
Galizzi, M.4
Moreno, S.N.J.5
-
27
-
-
34250162861
-
Kinetic characterization of squalene synthase from Trypanosoma cruzi: Selective inhibition by quinuclidine derivatives
-
DOI 10.1128/AAC.01454-06
-
Sealey-Cardona M, Cammerer S, Jones S, Ruiz-Pérez LM, Brun R, et al. (2007) Kinetic characterization of squalene synthase from trypanosoma cruzi: selective inhibition by quinuclidine derivatives. Antimicrob Agents Chemother 51: 2123-2129. (Pubitemid 46903104)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.6
, pp. 2123-2129
-
-
Sealey-Cardona, M.1
Cammerer, S.2
Jones, S.3
Ruiz-Perez, L.M.4
Brun, R.5
Gilbert, I.H.6
Urbina, J.A.7
Gonzalez-Pacanowska, D.8
-
28
-
-
84864386774
-
2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase
-
Rodrígues Poveda CA, González Pacanowska D, Szajnman SH, Rodríguez JB (2012) 2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase. Antimicrob Agents Chemother 56: 4483-4486.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4483-4486
-
-
Rodrígues Poveda, C.A.1
González Pacanowska, D.2
Szajnman, S.H.3
Rodríguez, J.B.4
-
29
-
-
38049100672
-
Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action
-
Gerpe A, Odreman Nuñez I, Draper P, Boiani L, Urbina JA, et al. (2008) Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action. Bioorg Med Chem 16: 569-577.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 569-577
-
-
Gerpe, A.1
Odreman Nuñez, I.2
Draper, P.3
Boiani, L.4
Urbina, J.A.5
-
30
-
-
73949135846
-
5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene
-
Gerpe A, Alvarez G, Benítez D, Boiani L, Quiroga M, et al. (2009) 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene. Bioorg Med Chem 17: 7500-7509.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 7500-7509
-
-
Gerpe, A.1
Alvarez, G.2
Benítez, D.3
Boiani, L.4
Quiroga, M.5
-
31
-
-
0035076959
-
Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors
-
DOI 10.1128/AAC.45.4.1210-1215.2001
-
Buckner FS, Griffin JH, Wilson AJ, Van Voorhis WC (2001) Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors. Antimicrob Agents Chemother 45: 1210-1215. (Pubitemid 32231002)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.4
, pp. 1210-1215
-
-
Buckner, F.S.1
Griffin, J.H.2
Wilson, A.J.3
Van Voorhis, W.C.4
-
32
-
-
11844279023
-
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii
-
DOI 10.1007/s11745-004-1323-2, L9600
-
Oliaro-Bosso S, Viola F, Matsuda S, Cravotto G, Tagliapietra S, et al. (2004) Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from saccharomyces cerevisiae, trypanosoma cruzi, and pneumocystis carinii. Lipids 39: 1007-1012. (Pubitemid 40095883)
-
(2004)
Lipids
, vol.39
, Issue.10
, pp. 1007-1012
-
-
Oliaro-Bosso, S.1
Viola, F.2
Matsuda, S.3
Cravotto, G.4
Tagliapietra, S.5
Balliano, G.6
-
33
-
-
46649116338
-
Inhibitory effect of umbelliferone aminoalkyl derivatives on oxidosqualene cyclases from S. cerevisiae, T. cruzi, P. carinii, H. sapiens, and A. thaliana: A structure-activity study
-
Oliaro Bosso S, Viola F, Taramino S, Tagliapietra S, Barge A, et al. (2007) Inhibitory effect of umbelliferone aminoalkyl derivatives on oxidosqualene cyclases from S. cerevisiae, T. cruzi, P. carinii, H. sapiens, and A. thaliana: a structure-activity study. ChemMedChem 2: 226-233.
-
(2007)
ChemMedChem
, vol.2
, pp. 226-233
-
-
Oliaro Bosso, S.1
Viola, F.2
Taramino, S.3
Tagliapietra, S.4
Barge, A.5
-
34
-
-
0142124194
-
Azasterols as Inhibitors of Sterol 24-Methyltransferase in Leishmania Species and Trypanosoma cruzi
-
DOI 10.1021/jm021114j
-
Magaraci F, Jimenez Jimenez C, Rodrigues C, Rodrigues JCF, Vianna Braga M, et al. (2003) Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. J Med Chem 46: 4714-4727. (Pubitemid 37271620)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.22
, pp. 4714-4727
-
-
Magaraci, F.1
Jimenez, J.C.2
Rodrigues, C.3
Rodrigues, J.C.F.4
Vianna, B.M.5
Yardley, V.6
De Luca-Fradley, K.7
Croft, S.L.8
De Souza, W.9
Ruiz-Perez, L.M.10
Urbina, J.11
Gonzalez, P.D.12
Gilbert, I.H.13
-
35
-
-
3342962349
-
Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis
-
DOI 10.1128/AAC.48.8.2937-2950.2004
-
Lorente SO, Rodrigues JCF, Jiménez Jiménez C, Joyce Menekse M, Rodrigues C, et al. (2004) Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. Antimicrob Agents Chemother 48: 2937-2950. (Pubitemid 38989159)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.8
, pp. 2937-2950
-
-
Lorente, S.O.1
Rodrigues, J.C.F.2
Jimenez, C.J.3
Joyce-Menekse, M.4
Rodrigues, C.5
Croft, S.L.6
Yardley, V.7
De Luca-Fradley, K.8
Ruiz-Perez, L.M.9
Urbina, J.10
De Souza, W.11
Gonzalez, P.D.12
Gilbert, I.H.13
-
36
-
-
28744437316
-
24(25)-sterol methyl transferase on the ultrastructure of epimastigotes of Trypanosoma cruzi
-
DOI 10.1017/S143192760505035X
-
Braga MV, Magaraci F, Lorente SO, Gilbert I, de Souza W (2005) Effects of inhibitors of Delta24(25)-sterol methyl transferase on the ultrastructure of epimastigotes of Trypanosoma cruzi. Microsc Microanal 11: 506-515. (Pubitemid 41758372)
-
(2005)
Microscopy and Microanalysis
, vol.11
, Issue.6
, pp. 506-515
-
-
Braga, M.V.1
Magaraci, F.2
Lorente, S.O.3
Gilbert, I.4
De Souza, W.5
-
37
-
-
0142227145
-
Specific chemotherapy of Chagas disease: Controversies and advances
-
DOI 10.1016/j.pt.2003.09.001
-
Urbina JA, Docampo R (2003) Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol 19: 495-501. (Pubitemid 37329658)
-
(2003)
Trends in Parasitology
, vol.19
, Issue.11
, pp. 495-501
-
-
Urbina, J.A.1
Docampo, R.2
-
38
-
-
0036156041
-
Molecular basis of resistance to azole antifungals
-
DOI 10.1016/S1471-4914(02)02280-3, PII S147149140102247X
-
Lupetti A, Danesi R, Campa M, Del Tacca M, Kelly S (2002) Molecular basis of resistance to azole antifungals. Trends Mol Med 8: 76-81. (Pubitemid 34094443)
-
(2002)
Trends in Molecular Medicine
, vol.8
, Issue.2
, pp. 76-81
-
-
Lupetti, A.1
Danesi, R.2
Campa, M.3
Tacca, M.D.4
Kelly, S.5
-
39
-
-
77749291956
-
Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: New substitutions and a review of the literature
-
Morio F, Loge C, Besse B, Hennequin C, Le Pape P (2010) Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature. Diagn Microbiol Infect Dis 66: 373-384.
-
(2010)
Diagn Microbiol Infect Dis
, vol.66
, pp. 373-384
-
-
Morio, F.1
Loge, C.2
Besse, B.3
Hennequin, C.4
Le Pape, P.5
-
40
-
-
84858983547
-
KEGG for integration and interpretation of large-scale molecular data sets
-
Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M (2012) KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 40: D109-D114.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Kanehisa, M.1
Goto, S.2
Sato, Y.3
Furumichi, M.4
Tanabe, M.5
-
41
-
-
33644787447
-
OrthoMCL-DB: Querying a comprehensive multi-species collection of ortholog groups
-
Chen F, Mackey AJ, Stoeckert CJ Jr, Roos DS (2006) OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups. Nucleic Acids Res 34: D363-D368.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Chen, F.1
Mackey, A.J.2
Stoeckert Jr., C.J.3
Roos, D.S.4
-
42
-
-
27744577599
-
Biogenesis, molecular regulation and function of plant isoprenoids
-
DOI 10.1016/j.plipres.2005.09.003, PII S0163782705000329
-
Bouvier F, Rahier A, Camara B (2005) Biogenesis, molecular regulation and function of plant isoprenoids. Prog Lipid Res 44: 357-429. (Pubitemid 41608703)
-
(2005)
Progress in Lipid Research
, vol.44
, Issue.6
, pp. 357-429
-
-
Bouvier, F.1
Rahier, A.2
Camara, B.3
-
43
-
-
77949881304
-
Phylogenomics of sterol synthesis: Insights into the origin, evolution, and diversity of a key eukaryotic feature
-
Desmond E, Gribaldo S (2009) Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature. Genome Biol Evol 1: 364-381.
-
(2009)
Genome Biol Evol
, vol.1
, pp. 364-381
-
-
Desmond, E.1
Gribaldo, S.2
-
44
-
-
84876546158
-
A tight link between orthologs and bidirectional best hits in bacterial and archaeal genomes
-
Wolf YI, Koonin EV (2012) A tight link between orthologs and bidirectional best hits in bacterial and archaeal genomes. Genome Biol Evol 4: 1286-1294.
-
(2012)
Genome Biol Evol
, vol.4
, pp. 1286-1294
-
-
Wolf, Y.I.1
Koonin, E.V.2
-
45
-
-
27644472372
-
Orthologs, paralogs, and evolutionary genomics
-
Koonin EV (2005) Orthologs, paralogs, and evolutionary genomics. Annu Rev Genet 39: 309-338.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 309-338
-
-
Koonin, E.V.1
-
47
-
-
84864622808
-
A simple strain typing assay for Trypanosoma cruzi: Discrimination of major evolutionary lineages from a single amplification product
-
Cosentino RO, Agüero F (2012) A simple strain typing assay for Trypanosoma cruzi: discrimination of major evolutionary lineages from a single amplification product. PLoS Negl Trop Dis 6: e1777.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Cosentino, R.O.1
Agüero, F.2
-
48
-
-
0034881536
-
Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages
-
DOI 10.1016/S0020-7519(01)00238-7, PII S0020751901002387
-
Brisse S, Verhoef J, Tibayrenc M (2001) Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol 31: 1218-1226. (Pubitemid 32762992)
-
(2001)
International Journal for Parasitology
, vol.31
, Issue.11
, pp. 1218-1226
-
-
Brisse, S.1
Verhoef, J.2
Tibayrenc, M.3
-
49
-
-
0037297395
-
Evidence for genetic exchange and hybridization in Trypanosoma cruzi based on nucleotide sequences and molecular karyotype
-
DOI 10.1016/S1567-1348(02)00097-7, PII S1567134802000977
-
Brisse S, Henriksson J, Barnabé C, Douzery EJP, Berkvens D, et al. (2003) Evidence for genetic exchange and hybridization in Trypanosoma cruzi based on nucleotide sequences and molecular karyotype. Infect Genet Evol 2: 173-183. (Pubitemid 36347778)
-
(2003)
Infection, Genetics and Evolution
, vol.2
, Issue.3
, pp. 173-183
-
-
Brisse, S.1
Henriksson, J.2
Barnabe, C.3
Douzery, E.J.P.4
Berkvens, D.5
Serrano, M.6
De Carvalho, M.R.C.7
Buck, G.A.8
Dujardin, J.-C.9
Tibayrenc, M.10
-
50
-
-
33645787855
-
Ancestral genomes, sex, and the population structure of Trypanosoma cruzi
-
de Freitas JM, Augusto Pinto L, Pimenta JR, Bastos Rodrigues L, Gonçalves VF, et al. (2006) Ancestral genomes, sex, and the population structure of Trypanosoma cruzi. PLoS Pathog 2: e24.
-
(2006)
PLoS Pathog
, vol.2
-
-
De Freitas, J.M.1
Augusto Pinto, L.2
Pimenta, J.R.3
Bastos Rodrigues, L.4
Gonçalves, V.F.5
-
51
-
-
70449592265
-
Comparative phylogeography of Trypanosoma cruzi TCIIc: New hosts, association with terrestrial ecotopes, and spatial clustering
-
Marcili A, Lima L, Valente VC, Valente SA, Batista JS, et al. (2009) Comparative phylogeography of Trypanosoma cruzi TCIIc: new hosts, association with terrestrial ecotopes, and spatial clustering. Infect Genet Evol 9: 1265-1274.
-
(2009)
Infect Genet Evol
, vol.9
, pp. 1265-1274
-
-
Marcili, A.1
Lima, L.2
Valente, V.C.3
Valente, S.A.4
Batista, J.S.5
-
52
-
-
73949161043
-
Genotyping of Trypanosoma cruzi: Systematic selection of assays allowing rapid and accurate discrimination of all known lineages
-
Lewis MD, Ma J, Yeo M, Carrasco HJ, Llewellyn MS, et al. (2009) Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. Am J Trop Med Hyg 81: 1041-1049.
-
(2009)
Am J Trop Med Hyg
, vol.81
, pp. 1041-1049
-
-
Lewis, M.D.1
Ma, J.2
Yeo, M.3
Carrasco, H.J.4
Llewellyn, M.S.5
-
53
-
-
79959858450
-
Multilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi
-
Yeo M, Mauricio IL, Messenger LA, Lewis MD, Llewellyn MS, et al. (2011) Multilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi. PLoS Negl Trop Dis 5: e1049.
-
(2011)
PLoS Negl Trop Dis
, vol.5
-
-
Yeo, M.1
Mauricio, I.L.2
Messenger, L.A.3
Lewis, M.D.4
Llewellyn, M.S.5
-
54
-
-
84857644998
-
Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: Validation using parasite stocks from the Chaco Region and a set of reference strains
-
Lauthier JJ, Tomasini N, Barnabé C, Monje Rumi MM, Alberti D'Amato AM, et al. (2012) Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: Validation using parasite stocks from the Chaco Region and a set of reference strains. Infect Genet Evol 12: 350-358.
-
(2012)
Infect Genet Evol
, vol.12
, pp. 350-358
-
-
Lauthier, J.J.1
Tomasini, N.2
Barnabé, C.3
Monje Rumi, M.M.4
Alberti D'Amato, A.M.5
-
55
-
-
77952358375
-
Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and uconazole
-
Chen CK, Leung SSF, Guilbert C, Jacobson MP, McKerrow JH, et al. (2010) Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and uconazole. PLoS Negl Trop Dis 4: e651.
-
(2010)
PLoS Negl Trop Dis
, vol.4
-
-
Chen, C.K.1
Leung, S.S.F.2
Guilbert, C.3
Jacobson, M.P.4
McKerrow, J.H.5
-
56
-
-
0032733078
-
Y132H substitution in Candida albicans sterol 14alpha-demethylase confers fluconazole resistance by preventing binding to haem
-
DOI 10.1016/S0378-1097(99)00478-4, PII S0378109799004784
-
Kelly SL, Lamb DC, Kelly DE (1999) Y132H substitution in Candida albicans sterol 14alphademethylase confers uconazole resistance by preventing binding to haem. FEMS Microbiol Lett 180: 171-175. (Pubitemid 29507563)
-
(1999)
FEMS Microbiology Letters
, vol.180
, Issue.2
, pp. 171-175
-
-
Kelly, S.L.1
Lamb, D.C.2
Kelly, D.E.3
-
57
-
-
0042544006
-
A mutation in the 14alpha-Demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor
-
Délye C, Laigret F, Corio Costet MF (1997) A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor. Appl Environ Microbiol 63: 2966-2970. (Pubitemid 27337780)
-
(1997)
Applied and Environmental Microbiology
, vol.63
, Issue.8
, pp. 2966-2970
-
-
Delye, C.1
Laigret, F.2
Corio-Costet, M.-F.3
-
58
-
-
76249100348
-
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections
-
Lepesheva GI, Park HW, Hargrove TY, Vanhollebeke B, Wawrzak Z, et al. (2010) Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections. J Biol Chem 285: 1773-1780.
-
(2010)
J Biol Chem
, vol.285
, pp. 1773-1780
-
-
Lepesheva, G.I.1
Park, H.W.2
Hargrove, T.Y.3
Vanhollebeke, B.4
Wawrzak, Z.5
-
59
-
-
34247137519
-
Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase
-
Sgraja T, Smith TK, Hunter WN (2007) Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. BMC Struct Biol 7: 20.
-
(2007)
BMC Struct Biol
, vol.7
, pp. 20
-
-
Sgraja, T.1
Smith, T.K.2
Hunter, W.N.3
-
60
-
-
0035717513
-
Nonorthologous gene displacement of phosphomevalonate kinase
-
DOI 10.1006/mgme.2000.3133
-
Houten SM, Waterham HR (2001) Nonorthologous gene displacement of phosphomevalonate 665 kinase. Mol Genet Metab 72: 273-276. (Pubitemid 34171447)
-
(2001)
Molecular Genetics and Metabolism
, vol.72
, Issue.3
, pp. 273-276
-
-
Houten, S.M.1
Waterham, H.R.2
-
61
-
-
50849101699
-
Crystal structure of human phosphomevalonate kinase at 1.8 A resolution
-
Chang Q, Yan XX, Gu SY, Liu JF, Liang DC (2008) Crystal structure of human phosphomevalonate kinase at 1.8 A resolution. Proteins 73: 254-258.
-
(2008)
Proteins
, vol.73
, pp. 254-258
-
-
Chang, Q.1
Yan, X.X.2
Gu, S.Y.3
Liu, J.F.4
Liang, D.C.5
-
62
-
-
0037327813
-
Fatty acid and sterol metabolism: Potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa
-
DOI 10.1016/S0166-6851(02)00280-3, PII S0166685102002803
-
Roberts CW, McLeod R, Rice DW, Ginger M, Chance ML, et al. (2003) Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Mol Biochem Parasitol 126: 129-142. (Pubitemid 36255612)
-
(2003)
Molecular and Biochemical Parasitology
, vol.126
, Issue.2
, pp. 129-142
-
-
Roberts, C.W.1
McLeod, R.2
Rice, D.W.3
Ginger, M.4
Chance, M.L.5
Goad, L.J.6
-
63
-
-
0033758773
-
The adaptative mechanisms of Trypanosoma brucei for sterol homeostasis in its different life-cycle environments
-
Coppens I, Courtoy PJ (2000) The adaptative mechanisms of Trypanosoma brucei for sterol homeostasis in its different life-cycle environments. Annu Rev Microbiol 54: 129-156.
-
(2000)
Annu Rev Microbiol
, vol.54
, pp. 129-156
-
-
Coppens, I.1
Courtoy, P.J.2
-
64
-
-
0032730353
-
Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes
-
DOI 10.1016/S0166-6851(99)00129-2, PII S0166685199001292
-
Liendo A, Visbal G, Piras MM, Piras R, Urbina JA (1999) Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes. Mol Biochem Parasitol 104: 81-91. (Pubitemid 29518445)
-
(1999)
Molecular and Biochemical Parasitology
, vol.104
, Issue.1
, pp. 81-91
-
-
Liendo, A.1
Visbal, G.2
Piras, M.M.3
Piras, R.4
Urbina, J.A.5
-
65
-
-
84863345834
-
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms
-
Nes CR, Singha UK, Liu J, Ganapathy K, Villalta F, et al. (2012) Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms. Biochem J 443: 267-277.
-
(2012)
Biochem J
, vol.443
, pp. 267-277
-
-
Nes, C.R.1
Singha, U.K.2
Liu, J.3
Ganapathy, K.4
Villalta, F.5
-
66
-
-
79953791492
-
Shotgun sequencing analysis of Trypanosoma cruzi I Sylvio X10/1 and comparison with T. cruzi VI CL Brener
-
Franzén O, Ochaya S, Sherwood E, Lewis MD, Llewellyn MS, et al. (2011) Shotgun sequencing analysis of Trypanosoma cruzi I Sylvio X10/1 and comparison with T. cruzi VI CL Brener. PLoS Negl Trop Dis 5: e984.
-
(2011)
PLoS Negl Trop Dis
, vol.5
-
-
Franzén, O.1
Ochaya, S.2
Sherwood, E.3
Lewis, M.D.4
Llewellyn, M.S.5
-
67
-
-
75549088870
-
TriTrypDB: A functional genomic resource for the Trypanosomatidae
-
Aslett M, Aurrecoechea C, Berriman M, Brestelli J, Brunk BP, et al. (2010) TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res 38: D457-D462.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Aslett, M.1
Aurrecoechea, C.2
Berriman, M.3
Brestelli, J.4
Brunk, B.P.5
-
68
-
-
84861232488
-
Characterization of bifunctional sphingolipid D 4-desaturases/C4- hydroxylases of trypanosomatids by liquid chromatographyelectrospray tandem mass spectrometry
-
Vacchina P, Tripodi KEJ, Escalante AM, Uttaro AD (2012) Characterization of bifunctional sphingolipid D 4-desaturases/C4-hydroxylases of trypanosomatids by liquid chromatographyelectrospray tandem mass spectrometry. Mol Biochem Parasitol 184: 29-38.
-
(2012)
Mol Biochem Parasitol
, vol.184
, pp. 29-38
-
-
Vacchina, P.1
Tripodi, K.E.J.2
Escalante, A.M.3
Uttaro, A.D.4
-
69
-
-
69049083506
-
The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi
-
Minning TA, Weatherly DB, Atwood J, Orlando R, Tarleton RL (2009) The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi. BMC Genomics 10: 370.
-
(2009)
BMC Genomics
, vol.10
, pp. 370
-
-
Minning, T.A.1
Weatherly, D.B.2
Atwood, J.3
Orlando, R.4
Tarleton, R.L.5
-
70
-
-
0037320283
-
The evolution of desaturases
-
DOI 10.1016/S0952-3278(02)00258-2, PII S0952327802002582
-
Sperling P, Ternes P, Zank TK, Heinz E (2003) The evolution of desaturases. Prostaglandins Leukot Essent Fatty Acids 68: 73-95. (Pubitemid 36216472)
-
(2003)
Prostaglandins Leukotrienes and Essential Fatty Acids
, vol.68
, Issue.2
, pp. 73-95
-
-
Sperling, P.1
Ternes, P.2
Zank, T.K.3
Heinz, E.4
-
72
-
-
79960967240
-
The impact of recombination on dN/dS within recently emerged bacterial clones
-
Castillo Ramírez S, Harris SR, Holden MTG, He M, Parkhill J, et al. (2011) The impact of recombination on dN/dS within recently emerged bacterial clones. PLoS Pathog 7: e1002129.
-
(2011)
PLoS Pathog
, vol.7
-
-
Castillo Ramírez, S.1
Harris, S.R.2
Holden, M.T.G.3
He, M.4
Parkhill, J.5
-
73
-
-
33644630612
-
Comparisons of dN/dS are time dependent for closely related bacterial genomes
-
Rocha EPC, Smith JM, Hurst LD, Holden MTG, Cooper JE, et al. (2006) Comparisons of dN/dS are time dependent for closely related bacterial genomes. J Theor Biol 239: 226-235.
-
(2006)
J Theor Biol
, vol.239
, pp. 226-235
-
-
Rocha, E.P.C.1
Smith, J.M.2
Hurst, L.D.3
Holden, M.T.G.4
Cooper, J.E.5
-
74
-
-
33749257454
-
First report of genetic hybrids between two very divergent Leishmania species: Leishmania infantum and Leishmania major
-
DOI 10.1016/j.ijpara.2006.06.019, PII S0020751906002554
-
Ravel C, Cortes S, Pratlong F, Morio F, Dedet JP, et al. (2006) First report of genetic hybrids between two very divergent Leishmania species: Leishmania infantum and Leishmania major. Int J Parasitol 36: 1383-1388. (Pubitemid 44485650)
-
(2006)
International Journal for Parasitology
, vol.36
, Issue.13
, pp. 1383-1388
-
-
Ravel, C.1
Cortes, S.2
Pratlong, F.3
Morio, F.4
Dedet, J.-P.5
Campino, L.6
-
75
-
-
34447626703
-
Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy
-
DOI 10.1073/pnas.0703678104
-
Lukes J, Mauricio IL, Schönian G, Dujardin JC, Soteriadou K, et al. (2007) Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy. Proc Natl Acad Sci U S A 104: 9375-9380. (Pubitemid 47185787)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.22
, pp. 9375-9380
-
-
Lukes, J.1
Mauricio, I.L.2
Schonian, G.3
Dujardin, J.-C.4
Soteriadou, K.5
Dedet, J.-P.6
Kuhls, K.7
Tintaya, K.W.Q.8
Jirku, M.9
Chocholova, E.10
Haralambous, C.11
Pratlong, F.12
Obornik, M.13
Horak, A.14
Ayala, F.J.15
Miles, M.A.16
-
76
-
-
58549098971
-
Population genetics of Trypanosoma brucei gambiense, the agent of sleeping sickness in Western Africa
-
Koffi M, De MeeÛs T, Bucheton B, Solano P, Camara M, et al. (2009) Population genetics of Trypanosoma brucei gambiense, the agent of sleeping sickness in Western Africa. Proc Natl Acad Sci U S A 106: 209-214.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 209-214
-
-
Koffi, M.1
De MeeÛs, T.2
Bucheton, B.3
Solano, P.4
Camara, M.5
-
77
-
-
84888253753
-
Population genetics of Trypanosoma brucei rhodesiense: Clonality and diversity within and between foci
-
Duffy CW, MacLean L, Sweeney L, Cooper A, Turner MRC, et al. (2013) Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci. PLoS Negl Trop Dis 7: e2526.
-
(2013)
PLoS Negl Trop Dis
, vol.7
-
-
Duffy, C.W.1
MacLean, L.2
Sweeney, L.3
Cooper, A.4
Turner, M.R.C.5
-
78
-
-
0031955518
-
Base-calling of automated sequencer traces using phred. I. Accuracy assessment
-
Ewing B, Hillier L, Wendl MC, Green P (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res 8: 175-185. (Pubitemid 28177229)
-
(1998)
Genome Research
, vol.8
, Issue.3
, pp. 175-185
-
-
Ewing, B.1
Hillier, L.2
Wendl, M.C.3
Green, P.4
-
79
-
-
0031978181
-
Base-calling of automated sequencer traces using phred. II. Error probabilities
-
Ewing B, Green P (1998) Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res 8: 186-194. (Pubitemid 28177230)
-
(1998)
Genome Research
, vol.8
, Issue.3
, pp. 186-194
-
-
Ewing, B.1
Green, P.2
-
80
-
-
0030872838
-
PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
-
DOI 10.1093/nar/25.14.2745
-
Nickerson DA, Tobe VO, Taylor SL (1997) PolyPhred: automating the detection and genotyping of single nucleotide substitutions using uorescence-based resequencing. Nucleic Acids Res 25: 2745-2751. (Pubitemid 27299787)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.14
, pp. 2745-2751
-
-
Nickerson, D.A.1
Tobe, V.O.2
Taylor, S.L.3
-
81
-
-
43349108713
-
Viewing and editing assembled sequences using Consed
-
Chapter 11: Unit11.2
-
Gordon D (2003) Viewing and editing assembled sequences using Consed. Curr Protoc Bioinformatics Chapter 11: Unit11.2.
-
(2003)
Curr Protoc Bioinformatics
-
-
Gordon, D.1
-
82
-
-
22244441812
-
The genome of the African trypanosome Trypanosoma brucei
-
Berriman M, Ghedin E, Hertz Fowler C, Blandin G, Renauld H, et al. (2005) The genome of the African trypanosome Trypanosoma brucei. Science 309: 416-422.
-
(2005)
Science
, vol.309
, pp. 416-422
-
-
Berriman, M.1
Ghedin, E.2
Hertz Fowler, C.3
Blandin, G.4
Renauld, H.5
-
83
-
-
77952329013
-
The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis
-
Jackson AP, Sanders M, Berry A, McQuillan J, Aslett MA, et al. (2010) The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis. PLoS Negl Trop Dis 4: e658.
-
(2010)
PLoS Negl Trop Dis
, vol.4
-
-
Jackson, A.P.1
Sanders, M.2
Berry, A.3
McQuillan, J.4
Aslett, M.A.5
-
84
-
-
84863229666
-
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species
-
Jackson AP, Berry A, Aslett M, Allison HC, Burton P, et al. (2012) Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species. Proc Natl Acad Sci U S A 109: 3416-3421.
-
(2012)
Proc Natl Acad Sci U S a
, vol.109
, pp. 3416-3421
-
-
Jackson, A.P.1
Berry, A.2
Aslett, M.3
Allison, H.C.4
Burton, P.5
-
85
-
-
22244437571
-
The genome of the kinetoplastid parasite, Leishmania major
-
Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, et al. (2005) The genome of the kinetoplastid parasite, Leishmania major. Science 309: 436-442.
-
(2005)
Science
, vol.309
, Issue.5733
, pp. 436-442
-
-
Ivens, A.C.1
Peacock, C.S.2
Worthey, E.A.3
Murphy, L.4
Aggarwal, G.5
-
86
-
-
34347339518
-
Comparative genomic analysis of three Leishmania species that cause diverse human disease
-
DOI 10.1038/ng2053, PII NG2053
-
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, et al. (2007) Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet 39: 839-847. (Pubitemid 47014491)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 839-847
-
-
Peacock, C.S.1
Seeger, K.2
Harris, D.3
Murphy, L.4
Ruiz, J.C.5
Quail, M.A.6
Peters, N.7
Adlem, E.8
Tivey, A.9
Aslett, M.10
Kerhornou, A.11
Ivens, A.12
Fraser, A.13
Rajandream, M.-A.14
Carver, T.15
Norbertczak, H.16
Chillingworth, T.17
Hance, Z.18
Jagels, K.19
Moule, S.20
Ormond, D.21
Rutter, S.22
Squares, R.23
Whitehead, S.24
Rabbinowitsch, E.25
Arrowsmith, C.26
White, B.27
Thurston, S.28
Bringaud, F.29
Baldauf, S.L.30
Faulconbridge, A.31
Jeffares, D.32
Depledge, D.P.33
Oyola, S.O.34
Hilley, J.D.35
Brito, L.O.36
Tosi, L.R.O.37
Barrell, B.38
Cruz, A.K.39
Mottram, J.C.40
Smith, D.F.41
Berriman, M.42
more..
-
87
-
-
83055181962
-
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
-
Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, et al. (2011) Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res 21: 2129-2142.
-
(2011)
Genome Res
, vol.21
, pp. 2129-2142
-
-
Rogers, M.B.1
Hilley, J.D.2
Dickens, N.J.3
Wilkes, J.4
Bates, P.A.5
-
88
-
-
77954272855
-
TranslatorX: Multiple alignment of nucleotide sequences guided by amino acid translations
-
Abascal F, Zardoya R, Telford MJ (2010) TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations. Nucleic Acids Res 38: W7-13.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Abascal, F.1
Zardoya, R.2
Telford, M.J.3
-
89
-
-
3042842589
-
A maximum likelihood method for detecting functional divergence at individual codon sites, with application to gene family evolution
-
Bielawski JP, Yang Z (2004) A maximum likelihood method for detecting functional divergence at individual codon sites, with application to gene family evolution. J Mol Evol 59: 121-132. (Pubitemid 38858437)
-
(2004)
Journal of Molecular Evolution
, vol.59
, Issue.1
, pp. 121-132
-
-
Bielawski, J.P.1
Yang, Z.2
-
91
-
-
32544436601
-
Multiple Alignment of protein structures and sequences for VMD
-
DOI 10.1093/bioinformatics/bti825
-
Eargle J, Wright D, Luthey Schulten Z (2006) Multiple Alignment of protein structures and sequences for VMD. Bioinformatics 22: 504-506. (Pubitemid 43231430)
-
(2006)
Bioinformatics
, vol.22
, Issue.4
, pp. 504-506
-
-
Eargle, J.1
Wright, D.2
Luthey-Schulten, Z.3
-
92
-
-
14144254724
-
High resolution crystal structures of human cytosolic thiolase (CT): A comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I
-
DOI 10.1016/j.jmb.2005.01.018
-
Kursula P, Sikkilä H, Fukao T, Kondo N, Wierenga RK (2005) High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I. J Mol Biol 347: 189-201. (Pubitemid 40283638)
-
(2005)
Journal of Molecular Biology
, vol.347
, Issue.1
, pp. 189-201
-
-
Kursula, P.1
Sikkila, H.2
Fukao, T.3
Kondo, N.4
Wierenga, R.K.5
-
93
-
-
33746835442
-
Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases
-
DOI 10.1073/pnas.0604935103
-
Pojer F, Ferrer JL, Richard SB, Nagegowda DA, Chye ML, et al. (2006) 743 Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc Natl Acad Sci U S A 103: 11491-11496. (Pubitemid 44182479)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.31
, pp. 11491-11496
-
-
Pojer, F.1
Ferrer, J.-L.2
Richard, S.B.3
Nagegowda, D.A.4
Chye, M.-L.5
Bach, T.J.6
Noel, J.P.7
-
94
-
-
38749124743
-
Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors
-
DOI 10.1016/j.bmcl.2007.11.124, PII S0960894X07014357
-
Park WKC, Kennedy RM, Larsen SD, Miller S, Roth BD, et al. (2008) Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. Bioorg Med Chem Lett 18: 1151-1156. (Pubitemid 351179323)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.3
, pp. 1151-1156
-
-
Park, W.K.C.1
Kennedy, R.M.2
Larsen, S.D.3
Miller, S.4
Roth, B.D.5
Song, Y.6
Steinbaugh, B.A.7
Sun, K.8
Tait, B.D.9
Kowala, M.C.10
Trivedi, B.K.11
Auerbach, B.12
Askew, V.13
Dillon, L.14
Hanselman, J.C.15
Lin, Z.16
Lu, G.H.17
Robertson, A.18
Sekerke, C.19
-
95
-
-
34447283565
-
Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity
-
DOI 10.1016/j.jmb.2007.05.094, PII S0022283607007656
-
Byres E, Alphey MS, Smith TK, Hunter WN (2007) Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. J Mol Biol 371: 540-553. (Pubitemid 47048287)
-
(2007)
Journal of Molecular Biology
, vol.371
, Issue.2
, pp. 540-553
-
-
Byres, E.1
Alphey, M.S.2
Smith, T.K.3
Hunter, W.N.4
-
96
-
-
30344437272
-
Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design
-
DOI 10.1002/prot.20754
-
Gabelli SB, McLellan JS, Montalvetti A, Oldfield E, Docampo R, et al. (2006) Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design. Proteins 62: 80-88. (Pubitemid 43063006)
-
(2006)
Proteins: Structure, Function and Genetics
, vol.62
, Issue.1
, pp. 80-88
-
-
Gabelli, S.B.1
McLellan, J.S.2
Montalvetti, A.3
Oldfield, E.4
Docampo, R.5
Amzel, L.M.6
-
97
-
-
0034730724
-
Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis
-
Pandit J, Danley DE, Schulte GK, Mazzalupo S, Pauly TA, et al. (2000) Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis. J Biol Chem 275: 30610-30617.
-
(2000)
J Biol Chem
, vol.275
, pp. 30610-30617
-
-
Pandit, J.1
Danley, D.E.2
Schulte, G.K.3
Mazzalupo, S.4
Pauly, T.A.5
-
98
-
-
8544273685
-
Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase
-
DOI 10.1038/nature02993
-
Thoma R, Schulz Gasch T, D'Arcy B, Benz J, Aebi J, et al. (2004) Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. Nature 432: 118-122. (Pubitemid 39490838)
-
(2004)
Nature
, vol.432
, Issue.7013
, pp. 118-122
-
-
Thoma, R.1
Schulz-Gasen, T.2
D'Arcy, B.3
Benz, J.4
Aebi, J.5
Dehmlow, H.6
Hennig, M.7
Stihle, M.8
Ruf, A.9
-
99
-
-
77955477571
-
Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi
-
Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, et al. (2010) Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. J Biol Chem 285: 25582-25590.
-
(2010)
J Biol Chem
, vol.285
, pp. 25582-25590
-
-
Lepesheva, G.I.1
Hargrove, T.Y.2
Anderson, S.3
Kleshchenko, Y.4
Furtak, V.5
-
100
-
-
33645639221
-
CYP51 from Trypanosoma cruzi: A phyla-specific residue in the B′ helix defines substrate preferences of sterol 14alpha-demethylase
-
DOI 10.1074/jbc.M510317200
-
Lepesheva GI, Zaitseva NG, Nes WD, Zhou W, Arase M, et al. (2006) CYP51 from Trypanosoma cruzi: a phyla-specific residue in the B′ helix defines substrate preferences of sterol 14alphademethylase. J Biol Chem 281: 3577-3585. (Pubitemid 43845975)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.6
, pp. 3577-3585
-
-
Lepesheva, G.I.1
Zaitseva, N.G.2
Nes, W.D.3
Zhou, W.4
Arase, M.5
Liu, J.6
Hill, G.C.7
Waterman, M.R.8
-
101
-
-
78649446542
-
Structural basis for conservation in the CYP51 family
-
Lepesheva GI, Waterman MR (2011) Structural basis for conservation in the CYP51 family. Biochim Biophys Acta 1814: 88-93.
-
(2011)
Biochim Biophys Acta
, vol.1814
, pp. 88-93
-
-
Lepesheva, G.I.1
Waterman, M.R.2
|