-
1
-
-
0019596893
-
Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi
-
Docampo R., Moreno S.N.J., Turrens J.F., Katzin A.M., Gonzales-Cappa S.M., Stoppani A.O.M. Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi. Mol. Biochem. Parasitol. 3:1981;169-180.
-
(1981)
Mol. Biochem. Parasitol.
, vol.3
, pp. 169-180
-
-
Docampo, R.1
Moreno, S.N.J.2
Turrens, J.F.3
Katzin, A.M.4
Gonzales-Cappa, S.M.5
Stoppani, A.O.M.6
-
2
-
-
0022497077
-
Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi
-
Beach D.H., Goad L.J., Holz G.G. Jr Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi. Biochem. Biophys. Res. Comm. 135:1986;851-856.
-
(1986)
Biochem. Biophys. Res. Comm.
, vol.135
, pp. 851-856
-
-
Beach, D.H.1
Goad, L.J.2
Holz G.G., Jr.3
-
3
-
-
0024202590
-
The activity of ketoconazole and other azoles against Trypanosoma cruzi: Biochemistry and chemotherapeutic action in vitro
-
Goad L.J., Berens R.L., Marr J.J., Beach D.H., Holz G.G. Jr The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro. Mol. Biochem. Parasitol. 32:1989;179-190.
-
(1989)
Mol. Biochem. Parasitol.
, vol.32
, pp. 179-190
-
-
Goad, L.J.1
Berens, R.L.2
Marr, J.J.3
Beach, D.H.4
Holz G.G., Jr.5
-
4
-
-
0024236768
-
Concentration and time dependence of the effects of ketoconazole on growth and sterol biosynthesis in Trypanosoma (Schizotrypanum) cruzi epimastigotes
-
Larralde G., Vivas J., Urbina J.A. Concentration and time dependence of the effects of ketoconazole on growth and sterol biosynthesis in Trypanosoma (Schizotrypanum) cruzi epimastigotes. Acta Cient. Venez. 39:1988;140-146.
-
(1988)
Acta Cient. Venez.
, vol.39
, pp. 140-146
-
-
Larralde, G.1
Vivas, J.2
Urbina, J.A.3
-
5
-
-
0023681312
-
Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
-
Urbina J.A., Lazardi K., Aguirre T., Piras M.M., Piras R. Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother. 32:1988;1237-1242.
-
(1988)
Antimicrob. Agents Chemother.
, vol.32
, pp. 1237-1242
-
-
Urbina, J.A.1
Lazardi, K.2
Aguirre, T.3
Piras, M.M.4
Piras, R.5
-
6
-
-
0025726299
-
Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
-
Urbina J.A., Lazardi K., Aguirre T., Piras M.M., Piras R. Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother. 35:1991;730-735.
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 730-735
-
-
Urbina, J.A.1
Lazardi, K.2
Aguirre, T.3
Piras, M.M.4
Piras, R.5
-
7
-
-
0027413385
-
Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: In vivo and in vitro studies
-
Urbina J.A., Lazardi K., Marchan E. et al. Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vivo and in vitro studies. Antimicrob. Agents Chemother. 37:1993;580-591.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 580-591
-
-
Urbina, J.A.1
Lazardi, K.2
Marchan, E.3
-
8
-
-
0027274006
-
Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas disease
-
Maldonado R.A., Molina J., Payares G., Urbina J.A. Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas disease. Antimicrob. Agents Chemother. 37:1993;1353-1359.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1353-1359
-
-
Maldonado, R.A.1
Molina, J.2
Payares, G.3
Urbina, J.A.4
-
11
-
-
9444291409
-
Cure of short- And long-term experimental Chagas disease using D0870
-
Urbina J.A., Payares G., Molina J. et al. Cure of short- and long-term experimental Chagas disease using D0870. Science. 273:1996;969-971.
-
(1996)
Science
, vol.273
, pp. 969-971
-
-
Urbina, J.A.1
Payares, G.2
Molina, J.3
-
12
-
-
0031941787
-
Antiproliferative effects and mechanism of action of D0870 and its S(-) enantiomer against Trypanosoma cruzi
-
Liendo A., Lazardi K., Urbina J.A. Antiproliferative effects and mechanism of action of D0870 and its S(-) enantiomer against Trypanosoma cruzi. J. Antimicrob. Chemother. 41:1998;197-205.
-
(1998)
J. Antimicrob. Chemother.
, vol.41
, pp. 197-205
-
-
Liendo, A.1
Lazardi, K.2
Urbina, J.A.3
-
13
-
-
0030921232
-
Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites
-
Urbina J.A. Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites. Parasitol. 117:1997;S91-S99.
-
(1997)
Parasitol
, vol.117
-
-
Urbina, J.A.1
-
14
-
-
0031807492
-
Antiproliferative effects and mechanism of action of SCH 56592 against Trypanosoma (Schizotrypanum) cruzi: In vitro and in vivo studies
-
Urbina J.A., Payares G., Contreras L.M. et al. Antiproliferative effects and mechanism of action of SCH 56592 against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies. Antimicrob. Agents Chemother. 42:1998;1771-1777.
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 1771-1777
-
-
Urbina, J.A.1
Payares, G.2
Contreras, L.M.3
-
15
-
-
0001870628
-
Rationally designed inhibitors of sterol biosynthesis
-
J. Sutcliffe, & N.H. Georgopapadakou. New York and London: Chapman and Hall
-
Oehlschlager A.C., Czyzewska E. Rationally designed inhibitors of sterol biosynthesis. Sutcliffe J., Georgopapadakou N.H. Emerging Targets in Antibacterial and Antifungal Chemotherapy. 1992;437-475 Chapman and Hall, New York and London.
-
(1992)
Emerging Targets in Antibacterial and Antifungal Chemotherapy
, pp. 437-475
-
-
Oehlschlager, A.C.1
Czyzewska, E.2
-
16
-
-
0027756211
-
Inhibitors of sterol biosynthesis and their applications
-
Mercer E.I. Inhibitors of sterol biosynthesis and their applications. Prog. Lipid Res. 32:1993;357-416.
-
(1993)
Prog. Lipid Res.
, vol.32
, pp. 357-416
-
-
Mercer, E.I.1
-
19
-
-
0024235435
-
Failure of ketoconazole to cure chronic murine Chagas disease
-
McCabe R.E. Failure of ketoconazole to cure chronic murine Chagas disease. J. Infect. Dis. 158:1988;1408-1409.
-
(1988)
J. Infect. Dis.
, vol.158
, pp. 1408-1409
-
-
McCabe, R.E.1
-
20
-
-
0026754232
-
Avaliacão da atividade terapêutica do itraconazol nas infecçoes crônicas, experimental e humana, pelo Trypanosoma cruzi
-
Moreira A.A.B., DeSouza H.B.W.T., Amato Neto V., Matsubara L., Pinto P.L.S., Tolezano J.E., Nunes E.V., Okumura M. Avaliacão da atividade terapêutica do itraconazol nas infecçoes crônicas, experimental e humana, pelo Trypanosoma cruzi. Rev. Inst. Med. Trop. Sao Paulo. 34:1992;177-180.
-
(1992)
Rev. Inst. Med. Trop. Sao Paulo
, vol.34
, pp. 177-180
-
-
Moreira, A.A.B.1
Desouza, H.B.W.T.2
Amato Neto, V.3
Matsubara, L.4
Pinto, P.L.S.5
Tolezano, J.E.6
Nunes, E.V.7
Okumura, M.8
-
21
-
-
0027484860
-
An experimental and clinical assay with ketoconazole in the treatment of Chagas disease
-
Brener Z., Cançado J.R., Galvão L.M., da Luz Z.M.P., Filardi L.dS., Pereira M.E.S., Santos L.M.T., Cançado C.B. An experimental and clinical assay with ketoconazole in the treatment of Chagas disease. Mem. Inst. Oswaldo Cruz. 88:1993;149-153.
-
(1993)
Mem. Inst. Oswaldo Cruz.
, vol.88
, pp. 149-153
-
-
Brener, Z.1
Cançado, J.R.2
Galvão, L.M.3
Da Luz, Z.M.P.4
Filardi, L.ds.5
Pereira, M.E.S.6
Santos, L.M.T.7
Cançado, C.B.8
-
22
-
-
0033003357
-
Chemotherapy of Chagas' disease: The how and the why
-
Urbina J.A. Chemotherapy of Chagas' disease: the how and the why. J. Mol. Med. 77:1999;332-338.
-
(1999)
J. Mol. Med.
, vol.77
, pp. 332-338
-
-
Urbina, J.A.1
-
23
-
-
0021150439
-
Ketoconazole inhibition of intracellular multiplication of Trypanosoma cruzi and protection against a lethal infection with the organism
-
McCabe R.E., Remington J.S., Araujo F.G. Ketoconazole inhibition of intracellular multiplication of Trypanosoma cruzi and protection against a lethal infection with the organism. J. Infect. Dis. 150:1984;594-601.
-
(1984)
J. Infect. Dis.
, vol.150
, pp. 594-601
-
-
McCabe, R.E.1
Remington, J.S.2
Araujo, F.G.3
-
24
-
-
0022541328
-
In vitro and in vivo effects of itraconazole against Trypanosoma cruzi
-
McCabe R.E., Remington J.S., Araujo F.G. In vitro and in vivo effects of itraconazole against Trypanosoma cruzi. Am. J. Trop. Med. Hyg. 35:1986;280-284.
-
(1986)
Am. J. Trop. Med. Hyg.
, vol.35
, pp. 280-284
-
-
McCabe, R.E.1
Remington, J.S.2
Araujo, F.G.3
-
25
-
-
0025872450
-
Ultrastructural alterations induced by ICI 195,739, a bis triazole with strong antiproliferative action against Trypanosma (Schizotrypanum) cruzi
-
Lazardi K., Urbina J.A., DeSouza W. Ultrastructural alterations induced by ICI 195,739, a bis triazole with strong antiproliferative action against Trypanosma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother. 35:1991;736-740.
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 736-740
-
-
Lazardi, K.1
Urbina, J.A.2
Desouza, W.3
-
26
-
-
0025114817
-
Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
-
Lazardi K., Urbina J.A., DeSouza W. Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother. 34:1990;2097-2105.
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 2097-2105
-
-
Lazardi, K.1
Urbina, J.A.2
Desouza, W.3
-
27
-
-
0030973599
-
Altered lipid composition and enzyme activities of plasma membranes from Trypanosoma (Schizotrypanum) cruzi epimastigotes grown in the presence of sterol biosynthesis inhibitors
-
Contreras L.M., Vivas J., Urbina J.A. Altered lipid composition and enzyme activities of plasma membranes from Trypanosoma (Schizotrypanum) cruzi epimastigotes grown in the presence of sterol biosynthesis inhibitors. Biochem. Pharmacol. 53:1997;697-704.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 697-704
-
-
Contreras, L.M.1
Vivas, J.2
Urbina, J.A.3
-
28
-
-
0021663835
-
Trypanosoma (Schizotrypanum) cruzi: Terminal oxidases in two growth phases in vitro
-
De Maio A., Urbina J.A. Trypanosoma (Schizotrypanum) cruzi: terminal oxidases in two growth phases in vitro. Acta Cient. Venez. 35:1984;136-141.
-
(1984)
Acta Cient. Venez.
, vol.35
, pp. 136-141
-
-
De Maio, A.1
Urbina, J.A.2
-
30
-
-
0001894935
-
Drug discovery: A chemist approach
-
J.F. Ryley. Berlin and New York: Springer Verlag
-
Boyle F.T. Drug discovery: a chemist approach. Ryley J.F. Chemotherapy of Fungal Infections. 1990;3-30 Springer Verlag, Berlin and New York.
-
(1990)
Chemotherapy of Fungal Infections
, pp. 3-30
-
-
Boyle, F.T.1
-
31
-
-
0002051693
-
Biochemical aspects of ergosterol biosynthesis inhibition
-
J. Sutcliffe, & N.H. Georgopapadakou. New York and London: Chapman and Hall
-
Barrett-Bee K., Ryder N.S. Biochemical aspects of ergosterol biosynthesis inhibition. Sutcliffe J., Georgopapadakou N.H. Emerging Targets in Antibacterial and Antifungal Chemotherapy. 1992;410-436 Chapman and Hall, New York and London.
-
(1992)
Emerging Targets in Antibacterial and Antifungal Chemotherapy
, pp. 410-436
-
-
Barrett-Bee, K.1
Ryder, N.S.2
-
32
-
-
0001150457
-
Synthesis of new epiminoisopentenoids
-
Parish E.J., Nes W.D. Synthesis of new epiminoisopentenoids. Synthet. Comm. 18:1988;221-226.
-
(1988)
Synthet. Comm.
, vol.18
, pp. 221-226
-
-
Parish, E.J.1
Nes, W.D.2
-
33
-
-
0028302446
-
Occurrence of specific sterols in Pneumocystis carinii
-
Florin-Christensen M., Florin-Christensen J., Wu Y.-P., Zhou L., Gupta A., Rudney H., Kaneshiro E.S. Occurrence of specific sterols in Pneumocystis carinii. Biochem. Biophys. Res. Comm. 198:1994;236-242.
-
(1994)
Biochem. Biophys. Res. Comm.
, vol.198
, pp. 236-242
-
-
Florin-Christensen, M.1
Florin-Christensen, J.2
Wu, Y.-P.3
Zhou, L.4
Gupta, A.5
Rudney, H.6
Kaneshiro, E.S.7
-
34
-
-
0028056625
-
Evidence for the presence of 'metabolic sterols' Pneumocystis: Identification and initial characterization of Pneumocystis carinii sterols
-
Kaneshiro E.S., Ellis J.E., Jayasimhulu K., Beach D.H. Evidence for the presence of 'metabolic sterols' Pneumocystis: identification and initial characterization of Pneumocystis carinii sterols. J. Euk. Microbiol. 41:1994;78-85.
-
(1994)
J. Euk. Microbiol.
, vol.41
, pp. 78-85
-
-
Kaneshiro, E.S.1
Ellis, J.E.2
Jayasimhulu, K.3
Beach, D.H.4
-
38
-
-
0011377276
-
Inhibition of sterol biosynthesis in higher plants by analogues of high energy carbocationic intermediates
-
P.J. Kuhn, A.P.J. Trinci, M.J. Jung, M.W. Goosey, & L.G. Copping. Berlin and Heidelberg: Springer Verlag
-
Rahier A., Taton M., Benveniste P. Inhibition of sterol biosynthesis in higher plants by analogues of high energy carbocationic intermediates. Kuhn P.J., Trinci A.P.J., Jung M.J., Goosey M.W., Copping L.G. Biochemistry of Cell Walls and Membranes in Fungi. 1990;205-221 Springer Verlag, Berlin and Heidelberg.
-
(1990)
Biochemistry of Cell Walls and Membranes in Fungi
, pp. 205-221
-
-
Rahier, A.1
Taton, M.2
Benveniste, P.3
-
39
-
-
0000574197
-
8,14-sterols in suspensions of cultures of bramble cells cultured with an azasterol antimycotic agent (A25822B)
-
8,14-sterols in suspensions of cultures of bramble cells cultured with an azasterol antimycotic agent (A25822B). Phytochem. 19:1980;525-530.
-
(1980)
Phytochem
, vol.19
, pp. 525-530
-
-
Schmitt, P.1
Scheid, F.2
Benveniste, P.3
-
40
-
-
0001673524
-
5α-stigmata-9(11)-en-3β-ol, a sterol from Costus speciosus roots
-
Gupta M.N., Lal R.N., Shukla Y.N. 5α-stigmata-9(11)-en-3β-ol, a sterol from Costus speciosus roots. Phytochem. 20:1981;2557-2559.
-
(1981)
Phytochem
, vol.20
, pp. 2557-2559
-
-
Gupta, M.N.1
Lal, R.N.2
Shukla, Y.N.3
-
41
-
-
0022992801
-
Effects of ketoconazole on sterol biosynthesis by Leishmania mexicana mexicana amastigotes in murine macrophage tumor cells
-
Berman J.D., Goad L.J., Beach D.H., Holz G.G. Jr Effects of ketoconazole on sterol biosynthesis by Leishmania mexicana mexicana amastigotes in murine macrophage tumor cells. Mol. Biochem. Parasitol. 20:1986;85-92.
-
(1986)
Mol. Biochem. Parasitol.
, vol.20
, pp. 85-92
-
-
Berman, J.D.1
Goad, L.J.2
Beach, D.H.3
Holz G.G., Jr.4
-
42
-
-
0024512892
-
Inhibition of cholesterol syntesis and cell growth by 24(R,S),25-epiminolanosterol and triparanol in cultured rat hepatoma cells
-
Popják G., Meenan A., Parish E.J., Nes W.D. Inhibition of cholesterol syntesis and cell growth by 24(R,S),25-epiminolanosterol and triparanol in cultured rat hepatoma cells. J. Biol. Chem. 264:1989;6230-6238.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 6230-6238
-
-
Popják, G.1
Meenan, A.2
Parish, E.J.3
Nes, W.D.4
|