Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 8, 2004, Pages 2937-2950

  Lorente, Silvia Orenes ^a   Rodrigues, Juliany C F ^c   Jiménez, Carmen Jiménez ^d   Joyce Menekse, Miranda ^a   Rodrigues, Carlos ^e   Croft, Simon L ^b   Yardley, Vanessa ^b   De Luca Fradley, Kate ^b   Ruiz Pérez, Luis M ^d   Urbina, Julio ^e   De Souza, Wanderley ^c   González Pacanowska, Dolores ^d   Gilbert, Ian H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^e INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; AZASTEROL DERIVATIVE; METHYLTRANSFERASE INHIBITOR; PRODRUG; S ADENOSYLMETHIONINE; S ADENOSYLMETHIONINE:DELTA24 STEROL METHYLTRANSFERASE INHIBITOR; STEROL; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; LEISHMANIA; LEISHMANIASIS; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS; TRYPOMASTIGOTE; ULTRASTRUCTURE;

ANIMALS; ANTIPROTOZOAL AGENTS; AZA COMPOUNDS; HUMANS; KB CELLS; LEISHMANIA DONOVANI; LEISHMANIA MAJOR; LEISHMANIA MEXICANA; LEISHMANIASIS; LIPIDS; METHYLTRANSFERASES; MICROSCOPY, ELECTRON; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

EID: 3342962349     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.8.2937-2950.2004     Document Type: Article

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