Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

Journal of Biological Chemistry

Volumn 275, Issue 39, 2000, Pages 30610-30617

  Pandit, Jayvardhan ^a   Danley, Dennis E ^a   Schulte, Gayle K ^a   Mazzalupo, Stacy ^a,b   Pauly, Thomas A ^a   Hayward, Cheryl M ^a   Hamanaka, Ernest S ^a   Thompson, John F ^a   Harwood Jr , H James ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; SQUALENE SYNTHASE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CHOLESTEROL SYNTHESIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITOR COMPLEX; PRIORITY JOURNAL;

EID: 0034730724     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004132200     Document Type: Article

References (37)