-
1
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
1:CAS:528:DC%2BD2sXmtFKjsro%3D 17512414
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K (2007) High-resolution profiling of histone methylations in the human genome. Cell 129:823-837
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
2
-
-
77958481159
-
Nucleosome-interacting proteins regulated by DNA and histone methylation
-
1:CAS:528:DC%2BC3cXhtlKhs7rO 3640253 21029866
-
Bartke T, Vermeulen M, Xhemalce B, Robson SC, Mann M, Kouzarides T (2010) Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 143:470-484
-
(2010)
Cell
, vol.143
, pp. 470-484
-
-
Bartke, T.1
Vermeulen, M.2
Xhemalce, B.3
Robson, S.C.4
Mann, M.5
Kouzarides, T.6
-
3
-
-
76049084596
-
Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma
-
1:CAS:528:DC%2BC3cXltlKgtA%3D%3D 2793312 20018718
-
Berdasco M, Ropero S, Setien F, Fraga MF, Lapunzina P, Losson R, Alaminos M, Cheung NK, Rahman N, Esteller M (2009) Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma. Proc Natl Acad Sci USA 106:21830-21835
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21830-21835
-
-
Berdasco, M.1
Ropero, S.2
Setien, F.3
Fraga, M.F.4
Lapunzina, P.5
Losson, R.6
Alaminos, M.7
Cheung, N.K.8
Rahman, N.9
Esteller, M.10
-
5
-
-
19944430797
-
Genomic maps and comparative analysis of histone modifications in human and mouse
-
1:CAS:528:DC%2BD2MXht1emtbc%3D 15680324
-
Bernstein BE, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey DK, Huebert DJ, McMahon S, Karlsson EK, Kulbokas EJ 3rd, Gingeras TR, Schreiber SL, Lander ES (2005) Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 120:169-181
-
(2005)
Cell
, vol.120
, pp. 169-181
-
-
Bernstein, B.E.1
Kamal, M.2
Lindblad-Toh, K.3
Bekiranov, S.4
Bailey, D.K.5
Huebert, D.J.6
McMahon, S.7
-
6
-
-
84886808164
-
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer
-
10.1093/nar/gkt601
-
Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A (2013) Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Res. doi: 10.1093/nar/gkt601
-
(2013)
Nucleic Acids Res
-
-
Bhattacharyya, S.1
Yu, Y.2
Suzuki, M.3
Campbell, N.4
Mazdo, J.5
Vasanthakumar, A.6
Bhagat, T.D.7
Nischal, S.8
Christopeit, M.9
Parekh, S.10
Steidl, U.11
Godley, L.12
Maitra, A.13
Greally, J.M.14
Verma, A.15
-
7
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
1:CAS:528:DC%2BD38Xos1ehsQ%3D%3D 11782440
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16:6-21
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
8
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
1:CAS:528:DC%2BD28XptVCltrY%3D 16955068
-
Bolden JE, Peart MJ, Johnstone RW (2006) Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov 5:769-784
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
9
-
-
19944432566
-
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia
-
1:CAS:528:DC%2BD2MXhtFCgsLo%3D 15466934
-
Byrd JC, Marcucci G, Parthun MR, Xiao JJ, Klisovic RB, Moran M, Lin TS, Liu S, Sklenar AR, Davis ME, Lucas DM, Fischer B, Shank R, Tejaswi SL, Binkley P, Wright J, Chan KK, Grever MR (2005) A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia. Blood 105:959-967
-
(2005)
Blood
, vol.105
, pp. 959-967
-
-
Byrd, J.C.1
Marcucci, G.2
Parthun, M.R.3
Xiao, J.J.4
Klisovic, R.B.5
Moran, M.6
Lin, T.S.7
Liu, S.8
Sklenar, A.R.9
Davis, M.E.10
Lucas, D.M.11
Fischer, B.12
Shank, R.13
Tejaswi, S.L.14
Binkley, P.15
Wright, J.16
Chan, K.K.17
Grever, M.R.18
-
10
-
-
79953056443
-
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
-
1:CAS:528:DC%2BC3MXjvVOhtLs%3D 3348545 21430779
-
Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI (2011) The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature 471:513-517
-
(2011)
Nature
, vol.471
, pp. 513-517
-
-
Ceol, C.J.1
Houvras, Y.2
Jane-Valbuena, J.3
Bilodeau, S.4
Orlando, D.A.5
Battisti, V.6
Fritsch, L.7
Lin, W.M.8
Hollmann, T.J.9
Ferre, F.10
Bourque, C.11
Burke, C.J.12
Turner, L.13
Uong, A.14
Johnson, L.A.15
Beroukhim, R.16
Mermel, C.H.17
Loda, M.18
Ait-Si-Ali, S.19
Garraway, L.A.20
Young, R.A.21
Zon, L.I.22
more..
-
11
-
-
84877097843
-
Inhibition of BET bromodomain targets genetically diverse glioblastoma
-
1:CAS:528:DC%2BC3sXlsVCmsLo%3D 23403638
-
Cheng Z, Gong Y, Ma Y, Lu K, Lu X, Pierce LA, Thompson RC, Muller S, Knapp S, Wang J (2013) Inhibition of BET bromodomain targets genetically diverse glioblastoma. Clin Cancer Res 19:1748-1759
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1748-1759
-
-
Cheng, Z.1
Gong, Y.2
Ma, Y.3
Lu, K.4
Lu, X.5
Pierce, L.A.6
Thompson, R.C.7
Muller, S.8
Knapp, S.9
Wang, J.10
-
12
-
-
79952395270
-
Cancer genomics: From discovery science to personalized medicine
-
1:CAS:528:DC%2BC3MXivVGnsLw%3D 21383744
-
Chin L, Andersen JN, Futreal PA (2011) Cancer genomics: from discovery science to personalized medicine. Nat Med 17:297-303
-
(2011)
Nat Med
, vol.17
, pp. 297-303
-
-
Chin, L.1
Andersen, J.N.2
Futreal, P.A.3
-
13
-
-
84863413030
-
Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma
-
1:CAS:528:DC%2BC38XksFGrsL8%3D 3302822 22428052
-
Christians A, Hartmann C, Benner A, Meyer J, von Deimling A, Weller M, Wick W, Weiler M (2012) Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma. PLoS One 7:e33449
-
(2012)
PLoS One
, vol.7
, pp. 33449
-
-
Christians, A.1
Hartmann, C.2
Benner, A.3
Meyer, J.4
Von Deimling, A.5
Weller, M.6
Wick, W.7
Weiler, M.8
-
14
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
1:CAS:528:DC%2BD1MXos1Ghtbg%3D 19355820
-
Clapier CR, Cairns BR (2009) The biology of chromatin remodeling complexes. Annu Rev Biochem 78:273-304
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 273-304
-
-
Clapier, C.R.1
Cairns, B.R.2
-
15
-
-
0028096611
-
High sensitivity mapping of methylated cytosines
-
1:CAS:528:DyaK2cXlvFOjsL4%3D 310266 8065911
-
Clark SJ, Harrison J, Paul CL, Frommer M (1994) High sensitivity mapping of methylated cytosines. Nucleic Acids Res 22:2990-2997
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2990-2997
-
-
Clark, S.J.1
Harrison, J.2
Paul, C.L.3
Frommer, M.4
-
16
-
-
80054788317
-
Histone modifiers in cancer: Friends or foes?
-
1:CAS:528:DC%2BC3MXhtlCgu7jO 3174261 21941619
-
Cohen I, Porȩba E, Kamieniarz K, Schneider R (2011) Histone modifiers in cancer: friends or foes? Genes Cancer 2(6):631-647
-
(2011)
Genes Cancer
, vol.2
, Issue.6
, pp. 631-647
-
-
Cohen, I.1
Porȩba, E.2
Kamieniarz, K.3
Schneider, R.4
-
17
-
-
58149171661
-
The ING gene family in the regulation of cell growth and tumorigenesis
-
1:CAS:528:DC%2BD1cXhsFahsbbO 2872195 18780289
-
Coles AH, Jones SN (2009) The ING gene family in the regulation of cell growth and tumorigenesis. J Cell Physiol 218:45-57
-
(2009)
J Cell Physiol
, vol.218
, pp. 45-57
-
-
Coles, A.H.1
Jones, S.N.2
-
18
-
-
84866544635
-
Mutations and deletions of ARID1A in breast tumors
-
1:CAS:528:DC%2BC38XhtlKrt7%2FI 22249247
-
Cornen S, Adelaide J, Bertucci F, Finetti P, Guille A, Birnbaum DJ, Birnbaum D, Chaffanet M (2012) Mutations and deletions of ARID1A in breast tumors. Oncogene 31:4255-4256
-
(2012)
Oncogene
, vol.31
, pp. 4255-4256
-
-
Cornen, S.1
Adelaide, J.2
Bertucci, F.3
Finetti, P.4
Guille, A.5
Birnbaum, D.J.6
Birnbaum, D.7
Chaffanet, M.8
-
19
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
1:CAS:528:DC%2BD3cXhtFCgsb0%3D 10655057
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C (2000) Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24:132-138
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
20
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
1:CAS:528:DC%2BD1MXhtFCqurjE 3467096 19763153
-
Croce CM (2009) Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10:704-714
-
(2009)
Nat Rev Genet
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
21
-
-
84863621527
-
Cancer epigenetics: From mechanism to therapy
-
1:CAS:528:DC%2BC38XpvFGjsLg%3D 22770212
-
Dawson MA, Kouzarides T (2012) Cancer epigenetics: from mechanism to therapy. Cell 150:12-27
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
22
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
19474426
-
Delhommeau F, Dupont S, Della Valle V, James C, Trannoy S, Masse A, Kosmider O, Le Couedic JP, Robert F, Alberdi A, Lecluse Y, Plo I, Dreyfus FJ, Marzac C, Casadevall N, Lacombe C, Romana SP, Dessen P, Soulier J, Viguie F, Fontenay M, Vainchenker W, Bernard OA (2009) Mutation in TET2 in myeloid cancers. N Engl J Med 360:2289-2301
-
(2009)
N Engl J Med
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della Valle, V.3
James, C.4
Trannoy, S.5
Masse, A.6
Kosmider, O.7
Le Couedic, J.P.8
Robert, F.9
Alberdi, A.10
Lecluse, Y.11
Plo, I.12
Dreyfus, F.J.13
Marzac, C.14
Casadevall, N.15
Lacombe, C.16
Romana, S.P.17
Dessen, P.18
Soulier, J.19
Viguie, F.20
Fontenay, M.21
Vainchenker, W.22
Bernard, O.A.23
more..
-
23
-
-
0034654669
-
MethyLight: A high-throughput assay to measure DNA methylation
-
1:CAS:528:DC%2BD3cXmtlGgsLk%3D 102836 10734209
-
Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, Danenberg PV, Laird PW (2000) MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 28:E32
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 32
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Blake, C.5
Shibata, D.6
Danenberg, P.V.7
Laird, P.W.8
-
24
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
1:CAS:528:DC%2BD2sXivVGktbk%3D 17339880
-
Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8:286-298
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
25
-
-
40849139208
-
Epigenetics in cancer
-
1:CAS:528:DC%2BD1cXjt1ahs7Y%3D 18337604
-
Esteller M (2008) Epigenetics in cancer. N Engl J Med 358:1148-1159
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
26
-
-
81355142141
-
Non-coding RNAs in human disease
-
1:CAS:528:DC%2BC3MXhsVyktrfL 22094949
-
Esteller M (2011) Non-coding RNAs in human disease. Nat Rev Genet 12:861-874
-
(2011)
Nat Rev Genet
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
27
-
-
23744457857
-
How epigenetics integrates nuclear functions. Workshop on epigenetics and chromatin: Transcriptional regulation and beyond
-
1:CAS:528:DC%2BD2MXlslWgtL0%3D 1369115 15976819
-
Esteller M, Almouzni G (2005) How epigenetics integrates nuclear functions. Workshop on epigenetics and chromatin: transcriptional regulation and beyond. EMBO Rep 6:624-628
-
(2005)
EMBO Rep
, vol.6
, pp. 624-628
-
-
Esteller, M.1
Almouzni, G.2
-
28
-
-
84869062853
-
Epigenetic regulation of miRNAs in cancer
-
1:CAS:528:DC%2BC3sXhvVais7jO 22956499
-
Fabbri M, Calore F, Paone A, Galli R, Calin GA (2013) Epigenetic regulation of miRNAs in cancer. Adv Exp Med Biol 754:137-148
-
(2013)
Adv Exp Med Biol
, vol.754
, pp. 137-148
-
-
Fabbri, M.1
Calore, F.2
Paone, A.3
Galli, R.4
Calin, G.A.5
-
29
-
-
68949213578
-
Insights from genomic profiling of transcription factors
-
1:CAS:528:DC%2BD1MXhtVWhsLzM 2846386 19668247
-
Farnham PJ (2009) Insights from genomic profiling of transcription factors. Nat Rev Genet 10:605-616
-
(2009)
Nat Rev Genet
, vol.10
, pp. 605-616
-
-
Farnham, P.J.1
-
30
-
-
1042278765
-
The history of cancer epigenetics
-
1:CAS:528:DC%2BD2cXks1CktA%3D%3D 14732866
-
Feinberg AP, Tycko B (2004) The history of cancer epigenetics. Nat Rev Cancer 4:143-153
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
31
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
1:CAS:528:DC%2BC3MXotlGmtA%3D%3D 3010259 20871596
-
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE (2010) Selective inhibition of BET bromodomains. Nature 468:1067-1073
-
(2010)
Nature
, vol.468
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
Morse, E.M.7
Keates, T.8
Hickman, T.T.9
Felletar, I.10
Philpott, M.11
Munro, S.12
McKeown, M.R.13
Wang, Y.14
Christie, A.L.15
West, N.16
Cameron, M.J.17
Schwartz, B.18
Heightman, T.D.19
La Thangue, N.20
French, C.A.21
Wiest, O.22
Kung, A.L.23
Knapp, S.24
Bradner, J.E.25
more..
-
32
-
-
0036753290
-
DNA methylation: A profile of methods and applications
-
634,636-49
-
Fraga MF, Esteller M (2002) DNA methylation: a profile of methods and applications. Biotechniques 33:632,634,636-49
-
(2002)
Biotechniques
, vol.33
, pp. 632
-
-
Fraga, M.F.1
Esteller, M.2
-
33
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
1:CAS:528:DC%2BD2MXislCmurg%3D 15765097
-
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Perez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37:391-400
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
Bonaldi, T.7
Haydon, C.8
Ropero, S.9
Petrie, K.10
Iyer, N.G.11
Perez-Rosado, A.12
Calvo, E.13
Lopez, J.A.14
Cano, A.15
Calasanz, M.J.16
Colomer, D.17
Piris, M.A.18
Ahn, N.19
Imhof, A.20
Caldas, C.21
Jenuwein, T.22
Esteller, M.23
more..
-
34
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
1:CAS:528:DC%2BD1MXptFWjuw%3D%3D 2612969 18955434
-
Friedman RC, Farh KK, Burge CB, Bartel DP (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19:92-105
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
35
-
-
18844465619
-
Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS)
-
101852 11917034
-
Frigola J, Ribas M, Risques RA, Peinado MA (2002) Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS). Nucleic Acids Res 30:e28
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 28
-
-
Frigola, J.1
Ribas, M.2
Risques, R.A.3
Peinado, M.A.4
-
36
-
-
84872856095
-
Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations
-
1:CAS:528:DC%2BC3sXit1Cgsrk%3D 3554679 23359823
-
Gao X, Huang M, Liu L, He Y, Yu Q, Zhao H, Zhou C, Zhang J, Zhu Z, Wan J, Jiang X, Gao Y (2013) Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations. PLoS One 8:e55169
-
(2013)
PLoS One
, vol.8
, pp. 55169
-
-
Gao, X.1
Huang, M.2
Liu, L.3
He, Y.4
Yu, Q.5
Zhao, H.6
Zhou, C.7
Zhang, J.8
Zhu, Z.9
Wan, J.10
Jiang, X.11
Gao, Y.12
-
37
-
-
77953393113
-
An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes
-
1:CAS:528:DC%2BC3cXjtVKhurw%3D
-
Garcia JS, Jain N, Godley LA (2010) An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes. Oncol Target Ther 3:1-13
-
(2010)
Oncol Target Ther
, vol.3
, pp. 1-13
-
-
Garcia, J.S.1
Jain, N.2
Godley, L.A.3
-
38
-
-
84875758730
-
Lessons from the cancer genome
-
1:CAS:528:DC%2BC3sXltVensb0%3D 23540688
-
Garraway LA, Lander ES (2013) Lessons from the cancer genome. Cell 153:17-37
-
(2013)
Cell
, vol.153
, pp. 17-37
-
-
Garraway, L.A.1
Lander, E.S.2
-
39
-
-
34548312368
-
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response
-
1:CAS:528:DC%2BD2sXps12ns7c%3D 17728759
-
Gorrini C, Squatrito M, Luise C, Syed N, Perna D, Wark L, Martinato F, Sardella D, Verrecchia A, Bennett S, Confalonieri S, Cesaroni M, Marchesi F, Gasco M, Scanziani E, Capra M, Mai S, Nuciforo P, Crook T, Lough J, Amati B (2007) Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature 448:1063-1067
-
(2007)
Nature
, vol.448
, pp. 1063-1067
-
-
Gorrini, C.1
Squatrito, M.2
Luise, C.3
Syed, N.4
Perna, D.5
Wark, L.6
Martinato, F.7
Sardella, D.8
Verrecchia, A.9
Bennett, S.10
Confalonieri, S.11
Cesaroni, M.12
Marchesi, F.13
Gasco, M.14
Scanziani, E.15
Capra, M.16
Mai, S.17
Nuciforo, P.18
Crook, T.19
Lough, J.20
Amati, B.21
more..
-
40
-
-
84863718299
-
Intronic RNAs mediate EZH2 regulation of epigenetic targets
-
1:CAS:528:DC%2BC38XnvVyrsLs%3D 22659877
-
Guil S, Soler M, Portela A, Carrere J, Fonalleras E, Gomez A, Villanueva A, Esteller M (2012) Intronic RNAs mediate EZH2 regulation of epigenetic targets. Nat Struct Mol Biol 19:664-670
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 664-670
-
-
Guil, S.1
Soler, M.2
Portela, A.3
Carrere, J.4
Fonalleras, E.5
Gomez, A.6
Villanueva, A.7
Esteller, M.8
-
41
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
1:CAS:528:DC%2BC3cXkslaru7w%3D 3049919 20393566
-
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464:1071-1076
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
Tsai, M.C.7
Hung, T.8
Argani, P.9
Rinn, J.L.10
Wang, Y.11
Brzoska, P.12
Kong, B.13
Li, R.14
West, R.B.15
Van De Vijver, M.J.16
Sukumar, S.17
Chang, H.Y.18
-
42
-
-
4143074854
-
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
-
1:CAS:528:DC%2BD2cXmtlOqt70%3D 15235609
-
Hamamoto R, Furukawa Y, Morita M, Iimura Y, Silva FP, Li M, Yagyu R, Nakamura Y (2004) SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nat Cell Biol 6:731-740
-
(2004)
Nat Cell Biol
, vol.6
, pp. 731-740
-
-
Hamamoto, R.1
Furukawa, Y.2
Morita, M.3
Iimura, Y.4
Silva, F.P.5
Li, M.6
Yagyu, R.7
Nakamura, Y.8
-
43
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352:9971003
-
(2005)
N Engl J Med
, vol.352
, pp. 9971003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
44
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
1:CAS:528:DC%2BD2sXitVOksbc%3D 17277777
-
Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, Hawkins RD, Barrera LO, Van Calcar S, Qu C, Ching KA, Wang W, Weng Z, Green RD, Crawford GE, Ren B (2007) Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 39:311-318
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.4
Ching, C.W.5
Hawkins, R.D.6
Barrera, L.O.7
Van Calcar, S.8
Qu, C.9
Ching, K.A.10
Wang, W.11
Weng, Z.12
Green, R.D.13
Crawford, G.E.14
Ren, B.15
-
45
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
1:CAS:528:DyaK28XlsFeht7Y%3D 38513 8790415
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93:9821-9826
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
46
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
1:CAS:528:DC%2BC38XhtFWgt7nJ 3387108 22689993
-
Heyn H, Li N, Ferreira HJ, Moran S, Pisano DG, Gomez A, Diez J, Sanchez-Mut JV, Setien F, Carmona FJ, Puca AA, Sayols S, Pujana MA, Serra-Musach J, Iglesias-Platas I, Formiga F, Fernandez AF, Fraga MF, Heath SC, Valencia A, Gut IG, Wang J, Esteller M (2012) Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci USA 109:10522-10527
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10522-10527
-
-
Heyn, H.1
Li, N.2
Ferreira, H.J.3
Moran, S.4
Pisano, D.G.5
Gomez, A.6
Diez, J.7
Sanchez-Mut, J.V.8
Setien, F.9
Carmona, F.J.10
Puca, A.A.11
Sayols, S.12
Pujana, M.A.13
Serra-Musach, J.14
Iglesias-Platas, I.15
Formiga, F.16
Fernandez, A.F.17
Fraga, M.F.18
Heath, S.C.19
Valencia, A.20
Gut, I.G.21
Wang, J.22
Esteller, M.23
more..
-
47
-
-
67749129007
-
DICER1 mutations in familial pleuropulmonary blastoma
-
1:CAS:528:DC%2BD1MXhtValsr3L 3098036 19556464
-
Hill DA, Ivanovich J, Priest JR, Gurnett CA, Dehner LP, Desruisseau D, Jarzembowski JA, Wikenheiser-Brokamp KA, Suarez BK, Whelan AJ, Williams G, Bracamontes D, Messinger Y, Goodfellow PJ (2009) DICER1 mutations in familial pleuropulmonary blastoma. Science 325:965
-
(2009)
Science
, vol.325
, pp. 965
-
-
Hill, D.A.1
Ivanovich, J.2
Priest, J.R.3
Gurnett, C.A.4
Dehner, L.P.5
Desruisseau, D.6
Jarzembowski, J.A.7
Wikenheiser-Brokamp, K.A.8
Suarez, B.K.9
Whelan, A.J.10
Williams, G.11
Bracamontes, D.12
Messinger, Y.13
Goodfellow, P.J.14
-
48
-
-
0033047813
-
Methylation profiling of CpG islands in human breast cancer cells
-
1:CAS:528:DyaK1MXhslKlsrc%3D 9949205
-
Huang TH, Perry MR, Laux DE (1999) Methylation profiling of CpG islands in human breast cancer cells. Hum Mol Genet 8:459-470
-
(1999)
Hum Mol Genet
, vol.8
, pp. 459-470
-
-
Huang, T.H.1
Perry, M.R.2
Laux, D.E.3
-
49
-
-
19944385935
-
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
-
1:CAS:528:DC%2BD2MXktVanug%3D%3D 15607963
-
Huntly BJ, Shigematsu H, Deguchi K, Lee BH, Mizuno S, Duclos N, Rowan R, Amaral S, Curley D, Williams IR, Akashi K, Gilliland DG (2004) MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell 6:587-596
-
(2004)
Cancer Cell
, vol.6
, pp. 587-596
-
-
Huntly, B.J.1
Shigematsu, H.2
Deguchi, K.3
Lee, B.H.4
Mizuno, S.5
Duclos, N.6
Rowan, R.7
Amaral, S.8
Curley, D.9
Williams, I.R.10
Akashi, K.11
Gilliland, D.G.12
-
50
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
1:CAS:528:DC%2BC38XhtlKrsL7M 3557932 22980975
-
Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansen S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Janne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M (2012) Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 150:1107-1120
-
(2012)
Cell
, vol.150
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
Hernandez, B.4
Pugh, T.J.5
Hodis, E.6
Cho, J.7
Suh, J.8
Capelletti, M.9
Sivachenko, A.10
Sougnez, C.11
Auclair, D.12
Lawrence, M.S.13
Stojanov, P.14
Cibulskis, K.15
Choi, K.16
De Waal, L.17
Sharifnia, T.18
Brooks, A.19
Greulich, H.20
Banerji, S.21
Zander, T.22
Seidel, D.23
Leenders, F.24
Ansen, S.25
Ludwig, C.26
Engel-Riedel, W.27
Stoelben, E.28
Wolf, J.29
Goparju, C.30
Thompson, K.31
Winckler, W.32
Kwiatkowski, D.33
Johnson, B.E.34
Janne, P.A.35
Miller, V.A.36
Pao, W.37
Travis, W.D.38
Pass, H.I.39
Gabriel, S.B.40
Lander, E.S.41
Thomas, R.K.42
Garraway, L.A.43
Getz, G.44
Meyerson, M.45
more..
-
51
-
-
34548746977
-
MicroRNA signatures in human ovarian cancer
-
1:CAS:528:DC%2BD2sXhtVCit7vN 17875710
-
Iorio MV, Visone R, Di Leva G, Donati V, Petrocca F, Casalini P, Taccioli C, Volinia S, Liu CG, Alder H, Calin GA, Menard S, Croce CM (2007) MicroRNA signatures in human ovarian cancer. Cancer Res 67:8699-8707
-
(2007)
Cancer Res
, vol.67
, pp. 8699-8707
-
-
Iorio, M.V.1
Visone, R.2
Di Leva, G.3
Donati, V.4
Petrocca, F.5
Casalini, P.6
Taccioli, C.7
Volinia, S.8
Liu, C.G.9
Alder, H.10
Calin, G.A.11
Menard, S.12
Croce, C.M.13
-
52
-
-
63549132021
-
Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors
-
1:CAS:528:DC%2BD1MXjtF2rsLk%3D 2668138 19276269
-
Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR, Tooke L, Perin JC, Xie H, Shaikh TH, Biegel JA (2009) Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. Clin Cancer Res 15:1923-1930
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1923-1930
-
-
Jackson, E.M.1
Sievert, A.J.2
Gai, X.3
Hakonarson, H.4
Judkins, A.R.5
Tooke, L.6
Perin, J.C.7
Xie, H.8
Shaikh, T.H.9
Biegel, J.A.10
-
53
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
1:CAS:528:DC%2BD2sXmtFSjtrg%3D 17540862
-
Johnson DS, Mortazavi A, Myers RM, Wold B (2007) Genome-wide mapping of in vivo protein-DNA interactions. Science 316:1497-1502
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
54
-
-
33744753061
-
DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset
-
1:CAS:528:DC%2BD28XksFeiur0%3D 16702365
-
Jones JS, Amos CI, Pande M, Gu X, Chen J, Campos IM, Wei Q, Rodriguez-Bigas M, Lynch PM, Frazier ML (2006) DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset. Cancer Epidemiol Biomarkers Prev 15:886-891
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 886-891
-
-
Jones, J.S.1
Amos, C.I.2
Pande, M.3
Gu, X.4
Chen, J.5
Campos, I.M.6
Wei, Q.7
Rodriguez-Bigas, M.8
Lynch, P.M.9
Frazier, M.L.10
-
55
-
-
77957731999
-
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
-
1:CAS:528:DC%2BC3cXht1Cgt77N 3076894 20826764
-
Jones S, Wang TL, Shih Ie M, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA Jr, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N (2010) Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 330:228-231
-
(2010)
Science
, vol.330
, pp. 228-231
-
-
Jones, S.1
Wang, T.L.2
Shih Ie, M.3
Mao, T.L.4
Nakayama, K.5
Roden, R.6
Glas, R.7
Slamon, D.8
Diaz, Jr.L.A.9
Vogelstein, B.10
Kinzler, K.W.11
Velculescu, V.E.12
Papadopoulos, N.13
-
56
-
-
29244447111
-
Loss of imprinting of IGF2: A common epigenetic modifier of intestinal tumor risk
-
1:CAS:528:DC%2BD2MXhtlWiurfK 16357124
-
Kaneda A, Feinberg AP (2005) Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk. Cancer Res 65:11236-11240
-
(2005)
Cancer Res
, vol.65
, pp. 11236-11240
-
-
Kaneda, A.1
Feinberg, A.P.2
-
57
-
-
32344450824
-
Genomic DNA methylation: The mark and its mediators
-
1:CAS:528:DC%2BD28XhsFKqsL8%3D 16403636
-
Klose RJ, Bird AP (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31:89-97
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
58
-
-
79955468280
-
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
-
1:CAS:528:DC%2BC3cXhsFGgtrrP 3230933 21151178
-
Kotake Y, Nakagawa T, Kitagawa K, Suzuki S, Liu N, Kitagawa M, Xiong Y (2011) Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene 30:1956-1962
-
(2011)
Oncogene
, vol.30
, pp. 1956-1962
-
-
Kotake, Y.1
Nakagawa, T.2
Kitagawa, K.3
Suzuki, S.4
Liu, N.5
Kitagawa, M.6
Xiong, Y.7
-
59
-
-
33847076849
-
Chromatin modifications and their function
-
1:CAS:528:DC%2BD2sXis12ju7Y%3D 17320507
-
Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693-705
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
60
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
1:CAS:528:DC%2BD2sXht1Wgsb%2FJ 17957188
-
Krivtsov AV, Armstrong SA (2007) MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7:823-833
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
61
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
1:CAS:528:DC%2BD3MXhsFCjtLc%3D 11237011
-
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J, Raymond C, Rosetti M, Santos R, Sheridan A, Sougnez C, Stange-Thomann N, Stojanovic N, Subramanian A, Wyman D, Rogers J, Sulston J, Ainscough R, Beck S, Bentley D, Burton J, Clee C, Carter N, Coulson A, Deadman R, Deloukas P, Dunham A, Dunham I, Durbin R, French L, Grafham D, Gregory S, Hubbard T, Humphray S, Hunt A, Jones M, Lloyd C, McMurray A, Matthews L, Mercer S, Milne S, Mullikin JC, Mungall A, Plumb R, Ross M, Shownkeen R, Sims S, Waterston RH, Wilson RK, Hillier LW, McPherson JD, Marra MA, Mardis ER, Fulton LA, Chinwalla AT, Pepin KH, Gish WR, Chissoe SL, Wendl MC, Delehaunty KD, Miner TL, Delehaunty A, Kramer JB, Cook LL, Fulton RS, Johnson DL, Minx PJ, Clifton SW, Hawkins T, Branscomb E, Predki P, Richardson P, Wenning S, Slezak T, Doggett N, Cheng JF, Olsen A, Lucas S, Elkin C, Uberbacher E, Frazier M et al (2001) Initial sequencing and analysis of the human genome. Nature 409:860-921
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
Levine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
Stange-Thomann, N.31
Stojanovic, N.32
Subramanian, A.33
Wyman, D.34
Rogers, J.35
Sulston, J.36
Ainscough, R.37
Beck, S.38
Bentley, D.39
Burton, J.40
Clee, C.41
Carter, N.42
Coulson, A.43
Deadman, R.44
Deloukas, P.45
Dunham, A.46
Dunham, I.47
Durbin, R.48
French, L.49
Grafham, D.50
Gregory, S.51
Hubbard, T.52
Humphray, S.53
Hunt, A.54
Jones, M.55
Lloyd, C.56
McMurray, A.57
Matthews, L.58
Mercer, S.59
Milne, S.60
Mullikin, J.C.61
Mungall, A.62
Plumb, R.63
Ross, M.64
Shownkeen, R.65
Sims, S.66
Waterston, R.H.67
Wilson, R.K.68
Hillier, L.W.69
McPherson, J.D.70
Marra, M.A.71
Mardis, E.R.72
Fulton, L.A.73
Chinwalla, A.T.74
Pepin, K.H.75
Gish, W.R.76
Chissoe, S.L.77
Wendl, M.C.78
Delehaunty, K.D.79
Miner, T.L.80
Delehaunty, A.81
Kramer, J.B.82
Cook, L.L.83
Fulton, R.S.84
Johnson, D.L.85
Minx, P.J.86
Clifton, S.W.87
Hawkins, T.88
Branscomb, E.89
Predki, P.90
Richardson, P.91
Wenning, S.92
Slezak, T.93
Doggett, N.94
Cheng, J.F.95
Olsen, A.96
Lucas, S.97
Elkin, C.98
Uberbacher, E.99
more..
-
62
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
1:CAS:528:DC%2BD1MXms1alu7s%3D 19483684
-
Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH (2009) Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet 41:838-842
-
(2009)
Nat Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
Massop, M.6
Stevens-Linders, E.7
Van Hoogen, P.8
Van Kessel, A.G.9
Raymakers, R.A.10
Kamping, E.J.11
Verhoef, G.E.12
Verburgh, E.13
Hagemeijer, A.14
Vandenberghe, P.15
De Witte, T.16
Van Der Reijden, B.A.17
Jansen, J.H.18
-
63
-
-
77956153243
-
The language of histone crosstalk
-
1:CAS:528:DC%2BC3cXhtFals7%2FO 3711869 20813257
-
Lee JS, Smith E, Shilatifard A (2010) The language of histone crosstalk. Cell 142:682-685
-
(2010)
Cell
, vol.142
, pp. 682-685
-
-
Lee, J.S.1
Smith, E.2
Shilatifard, A.3
-
64
-
-
38049044753
-
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer
-
1:CAS:528:DC%2BD1cXhtlynu7g%3D 17948228
-
Lehmann U, Hasemeier B, Christgen M, Muller M, Romermann D, Langer F, Kreipe H (2008) Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol 214:17-24
-
(2008)
J Pathol
, vol.214
, pp. 17-24
-
-
Lehmann, U.1
Hasemeier, B.2
Christgen, M.3
Muller, M.4
Romermann, D.5
Langer, F.6
Kreipe, H.7
-
65
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
1:CAS:528:DC%2BC3cXhsF2ltb7K 3201818 21067377
-
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, Osborne JR, Lin L, O'Laughlin M, McMichael JF, Delehaunty KD, McGrath SD, Fulton LA, Magrini VJ, Vickery TL, Hundal J, Cook LL, Conyers JJ, Swift GW, Reed JP, Alldredge PA, Wylie T, Walker J, Kalicki J, Watson MA, Heath S, Shannon WD, Varghese N, Nagarajan R, Westervelt P, Tomasson MH, Link DC, Graubert TA, DiPersio JF, Mardis ER, Wilson RK (2010) DNMT3A mutations in acute myeloid leukemia. N Engl J Med 363:2424-2433
-
(2010)
N Engl J Med
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
McLellan, M.D.4
Lamprecht, T.5
Larson, D.E.6
Kandoth, C.7
Payton, J.E.8
Baty, J.9
Welch, J.10
Harris, C.C.11
Lichti, C.F.12
Townsend, R.R.13
Fulton, R.S.14
Dooling, D.J.15
Koboldt, D.C.16
Schmidt, H.17
Zhang, Q.18
Osborne, J.R.19
Lin, L.20
O'Laughlin, M.21
McMichael, J.F.22
Delehaunty, K.D.23
McGrath, S.D.24
Fulton, L.A.25
Magrini, V.J.26
Vickery, T.L.27
Hundal, J.28
Cook, L.L.29
Conyers, J.J.30
Swift, G.W.31
Reed, J.P.32
Alldredge, P.A.33
Wylie, T.34
Walker, J.35
Kalicki, J.36
Watson, M.A.37
Heath, S.38
Shannon, W.D.39
Varghese, N.40
Nagarajan, R.41
Westervelt, P.42
Tomasson, M.H.43
Link, D.C.44
Graubert, T.A.45
Dipersio, J.F.46
Mardis, E.R.47
Wilson, R.K.48
more..
-
66
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
1:CAS:528:DyaK38XksVGgsr0%3D 1606615
-
Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
67
-
-
33847070442
-
The role of chromatin during transcription
-
1:CAS:528:DC%2BD2sXis12ju7c%3D 17320508
-
Li B, Carey M, Workman JL (2007) The role of chromatin during transcription. Cell 128:707-719
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
68
-
-
84868320535
-
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
-
1:CAS:528:DC%2BC38Xhs1eksbfJ 3483541 23028188
-
Liang H, Cheung LW, Li J, Ju Z, Yu S, Stemke-Hale K, Dogruluk T, Lu Y, Liu X, Gu C, Guo W, Scherer SE, Carter H, Westin SN, Dyer MD, Verhaak RG, Zhang F, Karchin R, Liu CG, Lu KH, Broaddus RR, Scott KL, Hennessy BT, Mills GB (2012) Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res 22:2120-2129
-
(2012)
Genome Res
, vol.22
, pp. 2120-2129
-
-
Liang, H.1
Cheung, L.W.2
Li, J.3
Ju, Z.4
Yu, S.5
Stemke-Hale, K.6
Dogruluk, T.7
Lu, Y.8
Liu, X.9
Gu, C.10
Guo, W.11
Scherer, S.E.12
Carter, H.13
Westin, S.N.14
Dyer, M.D.15
Verhaak, R.G.16
Zhang, F.17
Karchin, R.18
Liu, C.G.19
Lu, K.H.20
Broaddus, R.R.21
Scott, K.L.22
Hennessy, B.T.23
Mills, G.B.24
more..
-
69
-
-
70350231924
-
Loss of SNF5 expression correlates with poor patient survival in melanoma
-
1:CAS:528:DC%2BD1MXhtlyqsb%2FO 19808872
-
Lin H, Wong RP, Martinka M, Li G (2009) Loss of SNF5 expression correlates with poor patient survival in melanoma. Clin Cancer Res 15:6404-6411
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6404-6411
-
-
Lin, H.1
Wong, R.P.2
Martinka, M.3
Li, G.4
-
70
-
-
0037350661
-
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
-
1:CAS:528:DC%2BD3sXitFentbY%3D 12646957
-
Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing JR (2003) TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 17:637-641
-
(2003)
Leukemia
, vol.17
, pp. 637-641
-
-
Lorsbach, R.B.1
Moore, J.2
Mathew, S.3
Raimondi, S.C.4
Mukatira, S.T.5
Downing, J.R.6
-
71
-
-
84864869260
-
Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia
-
1:CAS:528:DC%2BC38XhtFOkt77J 22377896
-
Mar BG, Bullinger L, Basu E, Schlis K, Silverman LB, Dohner K, Armstrong SA (2012) Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia. Leukemia 26:1881-1883
-
(2012)
Leukemia
, vol.26
, pp. 1881-1883
-
-
Mar, B.G.1
Bullinger, L.2
Basu, E.3
Schlis, K.4
Silverman, L.B.5
Dohner, K.6
Armstrong, S.A.7
-
72
-
-
78751662908
-
The polycomb complex PRC2 and its mark in life
-
1:CAS:528:DC%2BC3MXnvVOisA%3D%3D 3760771 21248841
-
Margueron R, Reinberg D (2011) The polycomb complex PRC2 and its mark in life. Nature 469:343-349
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
73
-
-
84873720537
-
Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features
-
1:CAS:528:DC%2BC3sXitlWhtbk%3D 23163725
-
Matsubara D, Kishaba Y, Ishikawa S, Sakatani T, Oguni S, Tamura T, Hoshino H, Sugiyama Y, Endo S, Murakami Y, Aburatani H, Fukayama M, Niki T (2013) Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features. Cancer Sci 104:266-273
-
(2013)
Cancer Sci
, vol.104
, pp. 266-273
-
-
Matsubara, D.1
Kishaba, Y.2
Ishikawa, S.3
Sakatani, T.4
Oguni, S.5
Tamura, T.6
Hoshino, H.7
Sugiyama, Y.8
Endo, S.9
Murakami, Y.10
Aburatani, H.11
Fukayama, M.12
Niki, T.13
-
74
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
1:CAS:528:DC%2BD1MXhvFKjur0%3D 19219043
-
Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, Rossi S, Fernandez AF, Carneiro F, Oliveira C, Ferreira B, Liu CG, Villanueva A, Capella G, Schwartz S Jr, Shiekhattar R, Esteller M (2009) A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet 41:365-370
-
(2009)
Nat Genet
, vol.41
, pp. 365-370
-
-
Melo, S.A.1
Ropero, S.2
Moutinho, C.3
Aaltonen, L.A.4
Yamamoto, H.5
Calin, G.A.6
Rossi, S.7
Fernandez, A.F.8
Carneiro, F.9
Oliveira, C.10
Ferreira, B.11
Liu, C.G.12
Villanueva, A.13
Capella, G.14
Schwartz, Jr.S.15
Shiekhattar, R.16
Esteller, M.17
-
75
-
-
77957940475
-
A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells
-
1:CAS:528:DC%2BC3cXhtlSnu77I 20951941
-
Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S Jr, Esteller M (2010) A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 18:303-315
-
(2010)
Cancer Cell
, vol.18
, pp. 303-315
-
-
Melo, S.A.1
Moutinho, C.2
Ropero, S.3
Calin, G.A.4
Rossi, S.5
Spizzo, R.6
Fernandez, A.F.7
Davalos, V.8
Villanueva, A.9
Montoya, G.10
Yamamoto, H.11
Schwartz, Jr.S.12
Esteller, M.13
-
76
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
1:CAS:528:DC%2BC3cXntVGitQ%3D%3D 2850970 20081860
-
Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D, Humphries RK, Griffith OL, Shah S, Zhu H, Kimbara M, Shashkin P, Charlot JF, Tcherpakov M, Corbett R, Tam A, Varhol R, Smailus D, Moksa M, Zhao Y, Delaney A, Qian H, Birol I, Schein J, Moore R, Holt R, Horsman DE, Connors JM, Jones S, Aparicio S, Hirst M, Gascoyne RD, Marra MA (2010) Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 42:181-185
-
(2010)
Nat Genet
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
Paul, J.E.7
Boyle, M.8
Woolcock, B.W.9
Kuchenbauer, F.10
Yap, D.11
Humphries, R.K.12
Griffith, O.L.13
Shah, S.14
Zhu, H.15
Kimbara, M.16
Shashkin, P.17
Charlot, J.F.18
Tcherpakov, M.19
Corbett, R.20
Tam, A.21
Varhol, R.22
Smailus, D.23
Moksa, M.24
Zhao, Y.25
Delaney, A.26
Qian, H.27
Birol, I.28
Schein, J.29
Moore, R.30
Holt, R.31
Horsman, D.E.32
Connors, J.M.33
Jones, S.34
Aparicio, S.35
Hirst, M.36
Gascoyne, R.D.37
Marra, M.A.38
more..
-
77
-
-
77953644347
-
Reversal of histone methylation: Biochemical and molecular mechanisms of histone demethylases
-
1:CAS:528:DC%2BC3cXpslShsbk%3D 20373914
-
Mosammaparast N, Shi Y (2010) Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu Rev Biochem 79:155-179
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 155-179
-
-
Mosammaparast, N.1
Shi, Y.2
-
78
-
-
84856955226
-
The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
-
1:CAS:528:DC%2BC3MXotlCmu7k%3D 21725364
-
Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q, Yang H (2012) The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene 31:776-786
-
(2012)
Oncogene
, vol.31
, pp. 776-786
-
-
Niu, X.1
Zhang, T.2
Liao, L.3
Zhou, L.4
Lindner, D.J.5
Zhou, M.6
Rini, B.7
Yan, Q.8
Yang, H.9
-
79
-
-
33644836549
-
Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies
-
16330674
-
O'Connor OA, Heaney ML, Schwartz L, Richardson S, Willim R, MacGregor-Cortelli B, Curly T, Moskowitz C, Portlock C, Horwitz S, Zelenetz AD, Frankel S, Richon V, Marks P, Kelly WK (2006) Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies. J Clin Oncol 24:166-173
-
(2006)
J Clin Oncol
, vol.24
, pp. 166-173
-
-
O'Connor, O.A.1
Heaney, M.L.2
Schwartz, L.3
Richardson, S.4
Willim, R.5
Macgregor-Cortelli, B.6
Curly, T.7
Moskowitz, C.8
Portlock, C.9
Horwitz, S.10
Zelenetz, A.D.11
Frankel, S.12
Richon, V.13
Marks, P.14
Kelly, W.K.15
-
80
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
1:CAS:528:DyaK1MXnt1Gqsrc%3D 10555141
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
81
-
-
0041668072
-
Immunoprecipitation of native chromatin: NChIP
-
12893176
-
O'Neill LP, Turner BM (2003) Immunoprecipitation of native chromatin: NChIP. Methods 31:76-82
-
(2003)
Methods
, vol.31
, pp. 76-82
-
-
O'Neill, L.P.1
Turner, B.M.2
-
82
-
-
79251629946
-
The genetic landscape of the childhood cancer medulloblastoma
-
1:CAS:528:DC%2BC3MXpsF2lsw%3D%3D 3110744 21163964
-
Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE (2011) The genetic landscape of the childhood cancer medulloblastoma. Science 331:435-439
-
(2011)
Science
, vol.331
, pp. 435-439
-
-
Parsons, D.W.1
Li, M.2
Zhang, X.3
Jones, S.4
Leary, R.J.5
Lin, J.C.6
Boca, S.M.7
Carter, H.8
Samayoa, J.9
Bettegowda, C.10
Gallia, G.L.11
Jallo, G.I.12
Binder, Z.A.13
Nikolsky, Y.14
Hartigan, J.15
Smith, D.R.16
Gerhard, D.S.17
Fults, D.W.18
Vandenberg, S.19
Berger, M.S.20
Marie, S.K.21
Shinjo, S.M.22
Clara, C.23
Phillips, P.C.24
Minturn, J.E.25
Biegel, J.A.26
Judkins, A.R.27
Resnick, A.C.28
Storm, P.B.29
Curran, T.30
He, Y.31
Rasheed, B.A.32
Friedman, H.S.33
Keir, S.T.34
McLendon, R.35
Northcott, P.A.36
Taylor, M.D.37
Burger, P.C.38
Riggins, G.J.39
Karchin, R.40
Parmigiani, G.41
Bigner, D.D.42
Yan, H.43
Papadopoulos, N.44
Vogelstein, B.45
Kinzler, K.W.46
Velculescu, V.E.47
more..
-
83
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
1:CAS:528:DC%2BC3MXivFyqt7w%3D 3271441 21390126
-
Pasqualucci L, Dominguez-Sola D, Chiarenza A, Fabbri G, Grunn A, Trifonov V, Kasper LH, Lerach S, Tang H, Ma J, Rossi D, Chadburn A, Murty VV, Mullighan CG, Gaidano G, Rabadan R, Brindle PK, Dalla-Favera R (2011) Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature 471:189-195
-
(2011)
Nature
, vol.471
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
Fabbri, G.4
Grunn, A.5
Trifonov, V.6
Kasper, L.H.7
Lerach, S.8
Tang, H.9
Ma, J.10
Rossi, D.11
Chadburn, A.12
Murty, V.V.13
Mullighan, C.G.14
Gaidano, G.15
Rabadan, R.16
Brindle, P.K.17
Dalla-Favera, R.18
-
84
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
1:CAS:528:DC%2BC38XktlCqtLs%3D 3545649 22417203
-
Patel JP, Gonen M, Figueroa ME, Fernandez H, Sun Z, Racevskis J, Van Vlierberghe P, Dolgalev I, Thomas S, Aminova O, Huberman K, Cheng J, Viale A, Socci ND, Heguy A, Cherry A, Vance G, Higgins RR, Ketterling RP, Gallagher RE, Litzow M, van den Brink MR, Lazarus HM, Rowe JM, Luger S, Ferrando A, Paietta E, Tallman MS, Melnick A, Abdel-Wahab O, Levine RL (2012) Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med 366:1079-1089
-
(2012)
N Engl J Med
, vol.366
, pp. 1079-1089
-
-
Patel, J.P.1
Gonen, M.2
Figueroa, M.E.3
Fernandez, H.4
Sun, Z.5
Racevskis, J.6
Van Vlierberghe, P.7
Dolgalev, I.8
Thomas, S.9
Aminova, O.10
Huberman, K.11
Cheng, J.12
Viale, A.13
Socci, N.D.14
Heguy, A.15
Cherry, A.16
Vance, G.17
Higgins, R.R.18
Ketterling, R.P.19
Gallagher, R.E.20
Litzow, M.21
Van Den Brink, M.R.22
Lazarus, H.M.23
Rowe, J.M.24
Luger, S.25
Ferrando, A.26
Paietta, E.27
Tallman, M.S.28
Melnick, A.29
Abdel-Wahab, O.30
Levine, R.L.31
more..
-
85
-
-
73949149251
-
Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma
-
1:CAS:528:DC%2BD1MXhsFKkt7vO 2773225 19826128
-
Piekarz RL, Frye R, Turner M, Wright JJ, Allen SL, Kirschbaum MH, Zain J, Prince HM, Leonard JP, Geskin LJ, Reeder C, Joske D, Figg WD, Gardner ER, Steinberg SM, Jaffe ES, Stetler-Stevenson M, Lade S, Fojo AT, Bates SE (2009) Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma. J Clin Oncol 27:5410-5417
-
(2009)
J Clin Oncol
, vol.27
, pp. 5410-5417
-
-
Piekarz, R.L.1
Frye, R.2
Turner, M.3
Wright, J.J.4
Allen, S.L.5
Kirschbaum, M.H.6
Zain, J.7
Prince, H.M.8
Leonard, J.P.9
Geskin, L.J.10
Reeder, C.11
Joske, D.12
Figg, W.D.13
Gardner, E.R.14
Steinberg, S.M.15
Jaffe, E.S.16
Stetler-Stevenson, M.17
Lade, S.18
Fojo, A.T.19
Bates, S.E.20
more..
-
86
-
-
67650711140
-
Genome-wide views of chromatin structure
-
1:CAS:528:DC%2BD1MXos1Ghtbs%3D 2811691 19317649
-
Rando OJ, Chang HY (2009) Genome-wide views of chromatin structure. Annu Rev Biochem 78:245-271
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 245-271
-
-
Rando, O.J.1
Chang, H.Y.2
-
87
-
-
17744391429
-
Co-evolution of X-chromosome inactivation and imprinting in mammals
-
1:CAS:528:DC%2BD2MXjs1OksLo%3D 15818385
-
Reik W, Lewis A (2005) Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat Rev Genet 6:403-410
-
(2005)
Nat Rev Genet
, vol.6
, pp. 403-410
-
-
Reik, W.1
Lewis, A.2
-
88
-
-
79551572835
-
Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors
-
1:CAS:528:DC%2BC3MXktVGntr4%3D 21280140
-
Rodriguez-Nieto S, Canada A, Pros E, Pinto AI, Torres-Lanzas J, Lopez-Rios F, Sanchez-Verde L, Pisano DG, Sanchez-Cespedes M (2011) Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors. Hum Mutat 32:E1999-E2017
-
(2011)
Hum Mutat
, vol.32
-
-
Rodriguez-Nieto, S.1
Canada, A.2
Pros, E.3
Pinto, A.I.4
Torres-Lanzas, J.5
Lopez-Rios, F.6
Sanchez-Verde, L.7
Pisano, D.G.8
Sanchez-Cespedes, M.9
-
89
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
1:CAS:528:DC%2BC3MXivVGgtb8%3D 21386836
-
Rodriguez-Paredes M, Esteller M (2011) Cancer epigenetics reaches mainstream oncology. Nat Med 17:330-339
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
90
-
-
84901508481
-
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
-
doi: 10.1038/onc.2013.239
-
Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo PA, Carneiro F, Moura CS, Vieira J, Teixeira MR, Esteller M (2013) Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. Oncogene. doi: 10.1038/onc.2013.239
-
(2013)
Oncogene
-
-
Rodriguez-Paredes M, M.1
-
91
-
-
33646354640
-
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
-
1:CAS:528:DC%2BD28XjvVGksbY%3D 16642021
-
Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Boix-Chornet M, Caballero R, Alaminos M, Setien F, Paz MF, Herranz M, Palacios J, Arango D, Orntoft TF, Aaltonen LA, Schwartz S Jr, Esteller M (2006) A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat Genet 38:566-569
-
(2006)
Nat Genet
, vol.38
, pp. 566-569
-
-
Ropero, S.1
Fraga, M.F.2
Ballestar, E.3
Hamelin, R.4
Yamamoto, H.5
Boix-Chornet, M.6
Caballero, R.7
Alaminos, M.8
Setien, F.9
Paz, M.F.10
Herranz, M.11
Palacios, J.12
Arango, D.13
Orntoft, T.F.14
Aaltonen, L.A.15
Schwartz, Jr.S.16
Esteller, M.17
-
92
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
1:CAS:528:DC%2BD28Xmt1eksLY%3D 16766263
-
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9:435-443
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
93
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
1:CAS:528:DC%2BD2sXovFersro%3D 17694089
-
Saunders LR, Verdin E (2007) Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene 26:5489-5504
-
(2007)
Oncogene
, vol.26
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
94
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
1:CAS:528:DC%2BC38XhtlOrsro%3D 22286061
-
Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tonjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jager N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Fruhwald MC, Roggendorf W, Kramm C, Durken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N (2012) Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482:226-231
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.A.9
Tonjes, M.10
Hovestadt, V.11
Albrecht, S.12
Kool, M.13
Nantel, A.14
Konermann, C.15
Lindroth, A.16
Jager, N.17
Rausch, T.18
Ryzhova, M.19
Korbel, J.O.20
Hielscher, T.21
Hauser, P.22
Garami, M.23
Klekner, A.24
Bognar, L.25
Ebinger, M.26
Schuhmann, M.U.27
Scheurlen, W.28
Pekrun, A.29
Fruhwald, M.C.30
Roggendorf, W.31
Kramm, C.32
Durken, M.33
Atkinson, J.34
Lepage, P.35
Montpetit, A.36
Zakrzewska, M.37
Zakrzewski, K.38
Liberski, P.P.39
Dong, Z.40
Siegel, P.41
Kulozik, A.E.42
Zapatka, M.43
Guha, A.44
Malkin, D.45
Felsberg, J.46
Reifenberger, G.47
Von Deimling, A.48
Ichimura, K.49
Collins, V.P.50
Witt, H.51
Milde, T.52
Witt, O.53
Zhang, C.54
Castelo-Branco, P.55
Lichter, P.56
Faury, D.57
Tabori, U.58
Plass, C.59
Majewski, J.60
Pfister, S.M.61
Jabado, N.62
more..
-
95
-
-
67649826220
-
From DNA sequence to transcriptional behaviour: A quantitative approach
-
1:CAS:528:DC%2BD1MXnsVWgtL0%3D 2719885 19506578
-
Segal E, Widom J (2009) From DNA sequence to transcriptional behaviour: a quantitative approach. Nat Rev Genet 10:443-456
-
(2009)
Nat Rev Genet
, vol.10
, pp. 443-456
-
-
Segal, E.1
Widom, J.2
-
96
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
1:CAS:528:DC%2BD2MXls1Ontbg%3D 15988529
-
Seligson DB, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani SK (2005) Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-1266
-
(2005)
Nature
, vol.435
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
97
-
-
0036735345
-
A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer
-
1:CAS:528:DC%2BD38Xmslyksr8%3D 12208751
-
Shen H, Wang L, Spitz MR, Hong WK, Mao L, Wei Q (2002) A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer. Cancer Res 62:4992-4995
-
(2002)
Cancer Res
, vol.62
, pp. 4992-4995
-
-
Shen, H.1
Wang, L.2
Spitz, M.R.3
Hong, W.K.4
Mao, L.5
Wei, Q.6
-
98
-
-
79955648677
-
DNMT3B gene amplification predicts resistance to DNA demethylating drugs
-
1:CAS:528:DC%2BC3MXlslChsbg%3D 21484930
-
Simo-Riudalbas L, Melo SA, Esteller M (2011) DNMT3B gene amplification predicts resistance to DNA demethylating drugs. Genes Chromosom Cancer 50:527-534
-
(2011)
Genes Chromosom Cancer
, vol.50
, pp. 527-534
-
-
Simo-Riudalbas, L.1
Melo, S.A.2
Esteller, M.3
-
99
-
-
78650454078
-
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
-
1:CAS:528:DC%2BC3cXhsFyrsbnF 3000297 21078963
-
Sneeringer CJ, Scott MP, Kuntz KW, Knutson SK, Pollock RM, Richon VM, Copeland RA (2010) Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas. Proc Natl Acad Sci USA 107:20980-20985
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20980-20985
-
-
Sneeringer, C.J.1
Scott, M.P.2
Kuntz, K.W.3
Knutson, S.K.4
Pollock, R.M.5
Richon, V.M.6
Copeland, R.A.7
-
100
-
-
79959237464
-
Towards cracking the epigenetic code using a combination of high-throughput epigenomics and quantitative mass spectrometry-based proteomics
-
1:CAS:528:DC%2BC3MXnsFGqsbo%3D 21607996
-
Stunnenberg HG, Vermeulen M (2011) Towards cracking the epigenetic code using a combination of high-throughput epigenomics and quantitative mass spectrometry-based proteomics. BioEssays 33:547-551
-
(2011)
BioEssays
, vol.33
, pp. 547-551
-
-
Stunnenberg, H.G.1
Vermeulen, M.2
-
101
-
-
84859736577
-
Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer
-
1:CAS:528:DC%2BC3MXhtFWku7vP 3325596 21892211
-
Taniguchi H, Jacinto FV, Villanueva A, Fernandez AF, Yamamoto H, Carmona FJ, Puertas S, Marquez VE, Shinomura Y, Imai K, Esteller M (2012) Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer. Oncogene 31:1988-1994
-
(2012)
Oncogene
, vol.31
, pp. 1988-1994
-
-
Taniguchi, H.1
Jacinto, F.V.2
Villanueva, A.3
Fernandez, A.F.4
Yamamoto, H.5
Carmona, F.J.6
Puertas, S.7
Marquez, V.E.8
Shinomura, Y.9
Imai, K.10
Esteller, M.11
-
102
-
-
49249121155
-
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
-
1:CAS:528:DC%2BD1cXmsFKmtLo%3D 18519671
-
Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T (2008) Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 68:4123-4132
-
(2008)
Cancer Res
, vol.68
, pp. 4123-4132
-
-
Toyota, M.1
Suzuki, H.2
Sasaki, Y.3
Maruyama, R.4
Imai, K.5
Shinomura, Y.6
Tokino, T.7
-
103
-
-
0036962761
-
Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis
-
1:CAS:528:DC%2BD3sXlsVKisA%3D%3D 12481262
-
Uhlmann K, Brinckmann A, Toliat MR, Ritter H, Nurnberg P (2002) Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis 23:4072-4079
-
(2002)
Electrophoresis
, vol.23
, pp. 4072-4079
-
-
Uhlmann, K.1
Brinckmann, A.2
Toliat, M.R.3
Ritter, H.4
Nurnberg, P.5
-
104
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
1:CAS:528:DC%2BC3MXnsFaquw%3D%3D 3030920 21248752
-
Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P, Davies H, Jones D, Lin ML, Teague J, Bignell G, Butler A, Cho J, Dalgliesh GL, Galappaththige D, Greenman C, Hardy C, Jia M, Latimer C, Lau KW, Marshall J, McLaren S, Menzies A, Mudie L, Stebbings L, Largaespada DA, Wessels LF, Richard S, Kahnoski RJ, Anema J, Tuveson DA, Perez-Mancera PA, Mustonen V, Fischer A, Adams DJ, Rust A, Chan-on W, Subimerb C, Dykema K, Furge K, Campbell PJ, Teh BT, Stratton MR, Futreal PA (2011) Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469:539-542
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
Huang, D.4
Ong, C.K.5
Stephens, P.6
Davies, H.7
Jones, D.8
Lin, M.L.9
Teague, J.10
Bignell, G.11
Butler, A.12
Cho, J.13
Dalgliesh, G.L.14
Galappaththige, D.15
Greenman, C.16
Hardy, C.17
Jia, M.18
Latimer, C.19
Lau, K.W.20
Marshall, J.21
McLaren, S.22
Menzies, A.23
Mudie, L.24
Stebbings, L.25
Largaespada, D.A.26
Wessels, L.F.27
Richard, S.28
Kahnoski, R.J.29
Anema, J.30
Tuveson, D.A.31
Perez-Mancera, P.A.32
Mustonen, V.33
Fischer, A.34
Adams, D.J.35
Rust, A.36
Chan-On, W.37
Subimerb, C.38
Dykema, K.39
Furge, K.40
Campbell, P.J.41
Teh, B.T.42
Stratton, M.R.43
Futreal, P.A.44
more..
-
105
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
1:CAS:528:DC%2BD2sXhsVGjsLbK 18048652
-
Vasudevan S, Tong Y, Steitz JA (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318:1931-1934
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
106
-
-
0035895505
-
The sequence of the human genome
-
1:CAS:528:DC%2BD3MXhtlSgsbo%3D 11181995
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C et al (2001) The sequence of the human genome. Science 291:1304-1351
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
Broder, S.26
Clark, A.G.27
Nadeau, J.28
McKusick, V.A.29
Zinder, N.30
Levine, A.J.31
Roberts, R.J.32
Simon, M.33
Slayman, C.34
Hunkapiller, M.35
Bolanos, R.36
Delcher, A.37
Dew, I.38
Fasulo, D.39
Flanigan, M.40
Florea, L.41
Halpern, A.42
Hannenhalli, S.43
Kravitz, S.44
Levy, S.45
Mobarry, C.46
Reinert, K.47
Remington, K.48
Abu-Threideh, J.49
Beasley, E.50
Biddick, K.51
Bonazzi, V.52
Brandon, R.53
Cargill, M.54
Chandramouliswaran, I.55
Charlab, R.56
Chaturvedi, K.57
Deng, Z.58
Di Francesco, V.59
Dunn, P.60
Eilbeck, K.61
Evangelista, C.62
Gabrielian, A.E.63
Gan, W.64
Ge, W.65
Gong, F.66
Gu, Z.67
Guan, P.68
Heiman, T.J.69
Higgins, M.E.70
Ji, R.R.71
Ke, Z.72
Ketchum, K.A.73
Lai, Z.74
Lei, Y.75
Li, Z.76
Li, J.77
Liang, Y.78
Lin, X.79
Lu, F.80
Merkulov, G.V.81
Milshina, N.82
Moore, H.M.83
Naik, A.K.84
Narayan, V.A.85
Neelam, B.86
Nusskern, D.87
Rusch, D.B.88
Salzberg, S.89
Shao, W.90
Shue, B.91
Sun, J.92
Wang, Z.93
Wang, A.94
Wang, X.95
Wang, J.96
Wei, M.97
Wides, R.98
Xiao, C.99
more..
-
107
-
-
2642647094
-
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
-
1:CAS:528:DyaK1cXksFyltr0%3D 9671307
-
Versteege I, Sevenet N, Lange J, Rousseau-Merck MF, Ambros P, Handgretinger R, Aurias A, Delattre O (1998) Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203-206
-
(1998)
Nature
, vol.394
, pp. 203-206
-
-
Versteege, I.1
Sevenet, N.2
Lange, J.3
Rousseau-Merck, M.F.4
Ambros, P.5
Handgretinger, R.6
Aurias, A.7
Delattre, O.8
-
108
-
-
0002947085
-
The epigenotype
-
Waddington CH (1942) The epigenotype. Endeavour 1:18-20
-
(1942)
Endeavour
, vol.1
, pp. 18-20
-
-
Waddington, C.H.1
-
109
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
1:CAS:528:DyaK1cXms1amsLg%3D 9771701
-
Walsh CP, Chaillet JR, Bestor TH (1998) Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet 20:116-117
-
(1998)
Nat Genet
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
110
-
-
13444311619
-
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
-
545811 15635450
-
Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ (2005) Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. EMBO J 24:368-381
-
(2005)
EMBO J
, vol.24
, pp. 368-381
-
-
Wang, J.1
Iwasaki, H.2
Krivtsov, A.3
Febbo, P.G.4
Thorner, A.R.5
Ernst, P.6
Anastasiadou, E.7
Kutok, J.L.8
Kogan, S.C.9
Zinkel, S.S.10
Fisher, J.K.11
Hess, J.L.12
Golub, T.R.13
Armstrong, S.A.14
Akashi, K.15
Korsmeyer, S.J.16
-
111
-
-
34347392874
-
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
-
1:CAS:528:DC%2BD2sXntFemtLg%3D 17589499
-
Wang GG, Cai L, Pasillas MP, Kamps MP (2007) NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nat Cell Biol 9:804-812
-
(2007)
Nat Cell Biol
, vol.9
, pp. 804-812
-
-
Wang, G.G.1
Cai, L.2
Pasillas, M.P.3
Kamps, M.P.4
-
112
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
1:CAS:528:DC%2BD1cXnslKktL0%3D 2769248 18552846
-
Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S, Cui K, Roh TY, Peng W, Zhang MQ, Zhao K (2008) Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 40:897-903
-
(2008)
Nat Genet
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
Roh, T.Y.8
Peng, W.9
Zhang, M.Q.10
Zhao, K.11
-
113
-
-
84877113050
-
Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk
-
Wang JR, Gramling SJ, Goldstein DP, Cheng D, Chen D, Azad AK, Tse A, Hon H, Chen Z, Mirshams M, Simpson C, Huang SH, Marquez S, O'Sullivan B, Liu FF, Roberts H, Xu W, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Reisman DN, Liu G (2013) Association of two BRM promoter polymorphisms with head and neck squamous cell carcinoma risk. Carcinogenesis
-
(2013)
Carcinogenesis
-
-
Wang, J.R.1
Gramling, S.J.2
Goldstein, D.P.3
Cheng, D.4
Chen, D.5
Azad, A.K.6
Tse, A.7
Hon, H.8
Chen, Z.9
Mirshams, M.10
Simpson, C.11
Huang, S.H.12
Marquez, S.13
O'Sullivan, B.14
Liu, F.F.15
Roberts, H.16
Xu, W.17
Brown, D.H.18
Gilbert, R.W.19
Gullane, P.J.20
Irish, J.C.21
Reisman, D.N.22
Liu, G.23
more..
-
114
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
1:CAS:528:DC%2BD2MXmsFKmu7o%3D 16007088
-
Weber M, Davies JJ, Wittig D, Oakeley EJ, Haase M, Lam WL, Schubeler D (2005) Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 37:853-862
-
(2005)
Nat Genet
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
115
-
-
67649671961
-
Long noncoding RNAs: Functional surprises from the RNA world
-
1:CAS:528:DC%2BD1MXos1GitLw%3D 3152381 19571179
-
Wilusz JE, Sunwoo H, Spector DL (2009) Long noncoding RNAs: functional surprises from the RNA world. Genes Dev 23:1494-1504
-
(2009)
Genes Dev
, vol.23
, pp. 1494-1504
-
-
Wilusz, J.E.1
Sunwoo, H.2
Spector, D.L.3
-
116
-
-
0034326257
-
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines
-
1:CAS:528:DC%2BD3cXotV2lsbk%3D 11085541
-
Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, Iliev D, Penn B, Woodland AM, Smith R, Salada G, Carillo A, Laity K, Gupte J, Swedlund B, Tavtigian SV, Teng DH, Lees E (2000) BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 60:6171-6177
-
(2000)
Cancer Res
, vol.60
, pp. 6171-6177
-
-
Wong, A.K.1
Shanahan, F.2
Chen, Y.3
Lian, L.4
Ha, P.5
Hendricks, K.6
Ghaffari, S.7
Iliev, D.8
Penn, B.9
Woodland, A.M.10
Smith, R.11
Salada, G.12
Carillo, A.13
Laity, K.14
Gupte, J.15
Swedlund, B.16
Tavtigian, S.V.17
Teng, D.H.18
Lees, E.19
-
117
-
-
84862777410
-
St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome P, Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
1:CAS:528:DC%2BC38XhtlOlsb4%3D 3288377 22286216
-
Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, Mardis ER, Wilson RK, Downing JR, Ellison DW, Zhang J, Baker SJ (2012) St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome P, Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 44:251-253
-
(2012)
Nat Genet
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
Lu, C.4
Paugh, B.S.5
Becksfort, J.6
Qu, C.7
Ding, L.8
Huether, R.9
Parker, M.10
Zhang, J.11
Gajjar, A.12
Dyer, M.A.13
Mullighan, C.G.14
Gilbertson, R.J.15
Mardis, E.R.16
Wilson, R.K.17
Downing, J.R.18
Ellison, D.W.19
Zhang, J.20
Baker, S.J.21
more..
-
118
-
-
40949111565
-
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer
-
1:CAS:528:DC%2BD1cXjtFOhs74%3D 2915562 18339845
-
Xia W, Nagase S, Montia AG, Kalachikov SM, Keniry M, Su T, Memeo L, Hibshoosh H, Parsons R (2008) BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res 68:1667-1674
-
(2008)
Cancer Res
, vol.68
, pp. 1667-1674
-
-
Xia, W.1
Nagase, S.2
Montia, A.G.3
Kalachikov, S.M.4
Keniry, M.5
Su, T.6
Memeo, L.7
Hibshoosh, H.8
Parsons, R.9
-
119
-
-
35748937338
-
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer
-
1:CAS:528:DC%2BD2sXhtl2nur3F 17996646
-
Yu J, Cao Q, Mehra R, Laxman B, Yu J, Tomlins SA, Creighton CJ, Dhanasekaran SM, Shen R, Chen G, Morris DS, Marquez VE, Shah RB, Ghosh D, Varambally S, Chinnaiyan AM (2007) Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 12:419-431
-
(2007)
Cancer Cell
, vol.12
, pp. 419-431
-
-
Yu, J.1
Cao, Q.2
Mehra, R.3
Laxman, B.4
Yu, J.5
Tomlins, S.A.6
Creighton, C.J.7
Dhanasekaran, S.M.8
Shen, R.9
Chen, G.10
Morris, D.S.11
Marquez, V.E.12
Shah, R.B.13
Ghosh, D.14
Varambally, S.15
Chinnaiyan, A.M.16
-
120
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
1:CAS:528:DC%2BC38XhtVKjsro%3D 3267575 22237106
-
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG (2012) The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481:157-163
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
Wu, G.4
Heatley, S.L.5
Payne-Turner, D.6
Easton, J.7
Chen, X.8
Wang, J.9
Rusch, M.10
Lu, C.11
Chen, S.C.12
Wei, L.13
Collins-Underwood, J.R.14
Ma, J.15
Roberts, K.G.16
Pounds, S.B.17
Ulyanov, A.18
Becksfort, J.19
Gupta, P.20
Huether, R.21
Kriwacki, R.W.22
Parker, M.23
McGoldrick, D.J.24
Zhao, D.25
Alford, D.26
Espy, S.27
Bobba, K.C.28
Song, G.29
Pei, D.30
Cheng, C.31
Roberts, S.32
Barbato, M.I.33
Campana, D.34
Coustan-Smith, E.35
Shurtleff, S.A.36
Raimondi, S.C.37
Kleppe, M.38
Cools, J.39
Shimano, K.A.40
Hermiston, M.L.41
Doulatov, S.42
Eppert, K.43
Laurenti, E.44
Notta, F.45
Dick, J.E.46
Basso, G.47
Hunger, S.P.48
Loh, M.L.49
Devidas, M.50
Wood, B.51
Winter, S.52
Dunsmore, K.P.53
Fulton, R.S.54
Fulton, L.L.55
Hong, X.56
Harris, C.C.57
Dooling58
more..
-
121
-
-
84872653446
-
Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers
-
1:CAS:528:DC%2BC3sXhvFChs74%3D 3549982 23349767
-
Zhang X, Sun Q, Shan M, Niu M, Liu T, Xia B, Liang X, Wei W, Sun S, Zhang Y, Liu XS, Song Q, Yang Y, Ma Y, Liu Y, Yang L, Ren Y, Zhang G, Pang D (2013) Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers. PLoS One 8:e53931
-
(2013)
PLoS One
, vol.8
, pp. 53931
-
-
Zhang, X.1
Sun, Q.2
Shan, M.3
Niu, M.4
Liu, T.5
Xia, B.6
Liang, X.7
Wei, W.8
Sun, S.9
Zhang, Y.10
Liu, X.S.11
Song, Q.12
Yang, Y.13
Ma, Y.14
Liu, Y.15
Yang, L.16
Ren, Y.17
Zhang, G.18
Pang, D.19
-
122
-
-
84859305463
-
Recognition of methylated DNA through methyl-CpG binding domain proteins
-
1:CAS:528:DC%2BC38XkvFOktrw%3D 3315304 22110028
-
Zou X, Ma W, Solov'yov IA, Chipot C, Schulten K (2012) Recognition of methylated DNA through methyl-CpG binding domain proteins. Nucleic Acids Res 40(6):2747-2758
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.6
, pp. 2747-2758
-
-
Zou, X.1
Ma, W.2
Solov'Yov, I.A.3
Chipot, C.4
Schulten, K.5
|