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Volumn 50, Issue 7, 2011, Pages 527-534

DNMT3B gene amplification predicts resistance to DNA demethylating drugs

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTINEOPLASTIC AGENT; AZACITIDINE; DNA METHYLTRANSFERASE 3B; MESSENGER RNA; SGI 1027; UNCLASSIFIED DRUG;

EID: 79955648677     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20877     Document Type: Article
Times cited : (44)

References (40)
  • 1
    • 33746255899 scopus 로고    scopus 로고
    • Gene amplification in cancer
    • Albertson DG. 2006. Gene amplification in cancer. Trends Genet 22: 447-455.
    • (2006) Trends Genet , vol.22 , pp. 447-455
    • Albertson, D.G.1
  • 2
    • 0020614995 scopus 로고
    • Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma
    • Alitalo K, Schwab M, Lin CC, Varmus HE, Bishop JM. 1983. Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci USA 80: 1707-1711.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 1707-1711
    • Alitalo, K.1    Schwab, M.2    Lin, C.C.3    Varmus, H.E.4    Bishop, J.M.5
  • 4
    • 78149478781 scopus 로고    scopus 로고
    • Aberrant epigenetic landscape in cancer: How cellular identity goes awry
    • Berdasco M, Esteller M. 2010. Aberrant epigenetic landscape in cancer: How cellular identity goes awry. Dev Cell 19: 698-711.
    • (2010) Dev Cell , vol.19 , pp. 698-711
    • Berdasco, M.1    Esteller, M.2
  • 5
    • 66249127951 scopus 로고    scopus 로고
    • A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation
    • Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. 2009. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Cancer Res 69: 4277-4285.
    • (2009) Cancer Res , vol.69 , pp. 4277-4285
    • Datta, J.1    Ghoshal, K.2    Denny, W.A.3    Gamage, S.A.4    Brooke, D.G.5    Phiasivongsa, P.6    Redkar, S.7    Jacob, S.T.8
  • 6
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B. 2004. The history of cancer epigenetics. Nat Rev Cancer 4: 143-153.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 8
    • 79952092841 scopus 로고    scopus 로고
    • Hypomethylating agents and other novel strategies in myelodysplastic syndromes
    • Garcia-Manero G, Fenaux P. 2011. Hypomethylating agents and other novel strategies in myelodysplastic syndromes. J Clin Oncol 29: 516-523.
    • (2011) J Clin Oncol , vol.29 , pp. 516-523
    • Garcia-Manero, G.1    Fenaux, P.2
  • 9
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I, Tozlu S, Lidereau R, Bieche I. 2003. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res 9: 4415-4422.
    • (2003) Clin Cancer Res , vol.9 , pp. 4415-4422
    • Girault, I.1    Tozlu, S.2    Lidereau, R.3    Bieche, I.4
  • 15
    • 29644436321 scopus 로고    scopus 로고
    • Molecular enzymology of mammalian DNA methyltransferases
    • Jeltsch A. 2006. Molecular enzymology of mammalian DNA methyltransferases. Curr Top Microbiol Immunol 301: 203-225.
    • (2006) Curr Top Microbiol Immunol , vol.301 , pp. 203-225
    • Jeltsch, A.1
  • 16
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones PA, Taylor SM. 1980. Cellular differentiation, cytidine analogs and DNA methylation. Cell 20: 85-93.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 17
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. 2007. The epigenomics of cancer. Cell 128: 683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 19
    • 78649676706 scopus 로고    scopus 로고
    • Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells
    • Kuck D, Caulfield T, Lyko F, Medina-Franco JL. 2010. Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells. Mol Cancer Ther 9: 3015-3023.
    • (2010) Mol Cancer Ther , vol.9 , pp. 3015-3023
    • Kuck, D.1    Caulfield, T.2    Lyko, F.3    Medina-Franco, J.L.4
  • 25
    • 49049100885 scopus 로고    scopus 로고
    • Advances in the treatment of acute myeloid leukemia: from chromosomal aberrations to biologically targeted therapy
    • Lübbert M, Müller-Tidow C, Hofmann WK, Koeffler HP. 2008. Advances in the treatment of acute myeloid leukemia: from chromosomal aberrations to biologically targeted therapy. J Cell Biochem 104: 2059-2070.
    • (2008) J Cell Biochem , vol.104 , pp. 2059-2070
    • Lübbert, M.1    Müller-Tidow, C.2    Hofmann, W.K.3    Koeffler, H.P.4
  • 26
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 28
    • 58149516930 scopus 로고    scopus 로고
    • Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation
    • Rius M, Stresemann C, Keller D, Brom M, Schirrmacher E, Keppler D, Lyko F. 2009. Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. Mol Cancer Ther 8: 225-231.
    • (2009) Mol Cancer Ther , vol.8 , pp. 225-231
    • Rius, M.1    Stresemann, C.2    Keller, D.3    Brom, M.4    Schirrmacher, E.5    Keppler, D.6    Lyko, F.7
  • 29
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases, and cancer
    • Robertson KD. 2001. DNA methylation, methyltransferases, and cancer. Oncogene 20: 3139-3155.
    • (2001) Oncogene , vol.20 , pp. 3139-3155
    • Robertson, K.D.1
  • 30
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. 1999. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 27: 2291-2298.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6    Jones, P.A.7
  • 31
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • Rodriguez-Paredes M, Esteller M. 2011. Cancer epigenetics reaches mainstream oncology. Nat Med 17: 330-339.
    • (2011) Nat Med , vol.17 , pp. 330-339
    • Rodriguez-Paredes, M.1    Esteller, M.2
  • 32
    • 39649104991 scopus 로고    scopus 로고
    • DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
    • Roll JD, Rivenbark AG, Jones WD, Coleman WB. 2008. DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol Cancer 7: 15.
    • (2008) Mol Cancer , vol.7 , pp. 15
    • Roll, J.D.1    Rivenbark, A.G.2    Jones, W.D.3    Coleman, W.B.4
  • 34
    • 74049130225 scopus 로고    scopus 로고
    • Solving the Dnmt2 enigma
    • Schaefer M, Lyko F. 2010. Solving the Dnmt2 enigma. Chromosoma 119: 35-40.
    • (2010) Chromosoma , vol.119 , pp. 35-40
    • Schaefer, M.1    Lyko, F.2
  • 36
    • 0036735345 scopus 로고    scopus 로고
    • A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer
    • Shen H, Wang L, Spitz MR, Hong WK, Mao L, Wei Q. 2002. A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer. Cancer Res 62: 4992-4995.
    • (2002) Cancer Res , vol.62 , pp. 4992-4995
    • Shen, H.1    Wang, L.2    Spitz, M.R.3    Hong, W.K.4    Mao, L.5    Wei, Q.6
  • 39
    • 0042090217 scopus 로고    scopus 로고
    • DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras
    • Soejima K, Fang W, Rollins BJ. 2003. DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras. Oncogene 22: 4723-4733.
    • (2003) Oncogene , vol.22 , pp. 4723-4733
    • Soejima, K.1    Fang, W.2    Rollins, B.J.3
  • 40
    • 77958150580 scopus 로고    scopus 로고
    • Targeting DNA methylation for epigenetic therapy
    • Yang X, Lay F, Han H, Jones PA. 2010. Targeting DNA methylation for epigenetic therapy. Trends Pharmacol Sci 31: 536-546.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 536-546
    • Yang, X.1    Lay, F.2    Han, H.3    Jones, P.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.