Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis

Trends in Pharmacological Sciences

Volumn 35, Issue 5, 2014, Pages 227-236

  Zhen, Gehua ^a   Cao, Xu ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

articular cartilage; osteoarthritis; subchondral bone; TGF

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICULAR CARTILAGE; BONE REMODELING; BONE STRESS; CELL DIFFERENTIATION; DRUG MECHANISM; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HUMAN; MICROENVIRONMENT; NONHUMAN; OSTEOARTHRITIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

ARTICULAR CARTILAGE; OSTEOARTHRITIS; SUBCHONDRAL BONE; TGFΒ;

ANIMALS; BONE AND BONES; BONE REMODELING; CARTILAGE, ARTICULAR; CELLULAR MICROENVIRONMENT; HOMEOSTASIS; HUMANS; OSTEOARTHRITIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899651687     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2014.03.005     Document Type: Review

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