Alendronate protects against articular cartilage erosion by inhibiting subchondral bone loss in ovariectomized rats

Bone

Volumn 53, Issue 2, 2013, Pages 340-349

  Zhu, Songsong ^a   Chen, Kan ^a   Lan, Yu ^b   Zhang, Nan ^a   Jiang, Rulang ^b   Hu, Jing ^a  

^a SICHUAN UNIVERSITY   (China)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Alendronate; Cartilage; Micro CT; Osteoarthritis; Osteoporosis; Ovariectomy; Subchondral bone

Indexed keywords

ALENDRONIC ACID; COLLAGEN; COLLAGENASE 3; GELATINASE B; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; COLLAGEN DEGRADATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MODEL; EARLY INTERVENTION; FEMALE; HISTOPATHOLOGY; INHIBITION KINETICS; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOARTHRITIS; OSTEOLYSIS; OSTEOPOROSIS; OVARIECTOMY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; UPREGULATION;

ALENDRONATE; ANIMALS; CARTILAGE, ARTICULAR; FEMALE; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84872814281     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.12.044     Document Type: Article

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