Expression of a truncated, kinase-defective TGF-β type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

Journal of Cell Biology

Volumn 139, Issue 2, 1997, Pages 541-552

  Serra, Rosa ^a   Johnson, Mahlon ^b   Filvaroff, Ellen H ^c   LaBorde, James ^d   Sheehan, Daniel M ^d   Derynck, Rik ^c   Moses, Harold L ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 10; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; JOINT STIFFNESS; KYPHOSCOLIOSIS; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; BONE AND BONES; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; GENE EXPRESSION; GROWTH PLATE; HEDGEHOG PROTEINS; HUMANS; HYPERTROPHY; JOINTS; MICE; MICE, TRANSGENIC; OSTEOARTHRITIS; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; SYNOVIAL MEMBRANE; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030727351     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.2.541     Document Type: Article

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