Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes

Osteoarthritis and Cartilage

Volumn 18, Issue 11, 2010, Pages 1518-1527

  Finnson, K W ^a   Parker, W L ^a   Chi, Y ^a   Hoemann, C D ^b   Goldring, M B ^c   Antoniou, J ^a   Philip, A ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Chondrocyte; Dedifferentiation; Endoglin; Osteoarthritis; Smad; TGF beta

Indexed keywords

ENDOGLIN; LUCIFERASE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ASSAY; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTIGENS, CD; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; PHOSPHORYLATION; RECEPTORS, CELL SURFACE; SMAD PROTEINS, RECEPTOR-REGULATED; TRANSFORMING GROWTH FACTOR BETA;

EID: 78149413779     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.09.002     Document Type: Article

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